{"id":"https://openalex.org/W2944455294","doi":"https://doi.org/10.1134/s1062359018060122","title":"The Role of the Canonical Wnt-Signaling Pathway in Morphogenesis and Regeneration of the Adrenal Cortex in Rats Exposed to the Endocrine Disruptor Dichlorodiphenyltrichloroethane during Prenatal and Postnatal Development","display_name":"The Role of the Canonical Wnt-Signaling Pathway in Morphogenesis and Regeneration of the Adrenal Cortex in Rats Exposed to the Endocrine Disruptor Dichlorodiphenyltrichloroethane during Prenatal and Postnatal Development","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2944455294","doi":"https://doi.org/10.1134/s1062359018060122","mag":"2944455294"},"language":"en","primary_location":{"id":"doi:10.1134/s1062359018060122","doi":"https://doi.org/10.1134/s1062359018060122","is_oa":false,"landing_page_url":"https://doi.org/10.1134/s1062359018060122","pdf_url":null,"source":{"id":"https://openalex.org/S4210230782","display_name":"Biology Bulletin","issn_l":"1062-3590","issn":["1062-3590","1608-3059"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology Bulletin","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000309293","display_name":"Nataliya Valentinovna Yaglova","orcid":"https://orcid.org/0000-0002-8239-5039","observed_orcids":["https://orcid.org/0000-0002-8239-5039"]},"institutions":[{"id":"https://openalex.org/I4210145101","display_name":"Research Institute of Human Morphology","ror":"https://ror.org/042k8ng80","country_code":"RU","type":"nonprofit","lineage":["https://openalex.org/I4210145101"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"N. V. Yaglova","raw_affiliation_strings":["Research Institute of Human Morphology, 117418, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Human Morphology, 117418, Moscow, Russia","institution_ids":["https://openalex.org/I4210145101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081479231","display_name":"Dibakhan Aslanbekovna Tsomartova","orcid":"https://orcid.org/0000-0002-1381-0200","observed_orcids":["https://orcid.org/0000-0002-1381-0200"]},"institutions":[{"id":"https://openalex.org/I4210145101","display_name":"Research Institute of Human Morphology","ror":"https://ror.org/042k8ng80","country_code":"RU","type":"nonprofit","lineage":["https://openalex.org/I4210145101"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"D. A. Tsomartova","raw_affiliation_strings":["Research Institute of Human Morphology, 117418, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Human Morphology, 117418, Moscow, Russia","institution_ids":["https://openalex.org/I4210145101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018396512","display_name":"Sergey Stanislavovich Obernikhin","orcid":"https://orcid.org/0000-0003-0997-6766","observed_orcids":["https://orcid.org/0000-0003-0997-6766"]},"institutions":[{"id":"https://openalex.org/I4210145101","display_name":"Research Institute of Human Morphology","ror":"https://ror.org/042k8ng80","country_code":"RU","type":"nonprofit","lineage":["https://openalex.org/I4210145101"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"S. S. Obernikhin","raw_affiliation_strings":["Research Institute of Human Morphology, 117418, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Human Morphology, 117418, Moscow, Russia","institution_ids":["https://openalex.org/I4210145101"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034062624","display_name":"Svetlana Vladimirovna Nazimova","orcid":"https://orcid.org/0000-0001-5118-7037","observed_orcids":["https://orcid.org/0000-0001-5118-7037"]},"institutions":[{"id":"https://openalex.org/I4210145101","display_name":"Research Institute of Human Morphology","ror":"https://ror.org/042k8ng80","country_code":"RU","type":"nonprofit","lineage":["https://openalex.org/I4210145101"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"S. V. Nazimova","raw_affiliation_strings":["Research Institute of Human Morphology, 117418, Moscow, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute of Human Morphology, 117418, Moscow, Russia","institution_ids":["https://openalex.org/I4210145101"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5000309293"],"corresponding_institution_ids":["https://openalex.org/I4210145101"],"apc_list":null,"apc_paid":null,"fwci":1.0578,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.69836328,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"46","issue":"1","first_page":"74","last_page":"81"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.7910000085830688,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10686","display_name":"Effects and risks of endocrine disrupting chemicals","score":0.7910000085830688,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10929","display_name":"Wnt/\u03b2-catenin signaling in development and cancer","score":0.15719999372959137,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.005100000184029341,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/wnt-beta-catenin-signaling","display_name":"Wnt/\u03b2-catenin signaling","score":0.8759999871253967},{"id":"https://openalex.org/keywords/ddt","display_name":"DDT","score":0.7609999775886536},{"id":"https://openalex.org/keywords/endocrine-disruptors","display_name":"endocrine disruptors","score":0.9660000205039978},{"id":"https://openalex.org/keywords/adrenal-cortex","display_name":"adrenal cortex","score":0.8519999980926514},{"id":"https://openalex.org/keywords/adrenal-regeneration","display_name":"adrenal regeneration","score":0.9419999718666077},{"id":"https://openalex.org/keywords/zona-glomerulosa","display_name":"zona glomerulosa","score":0.8009999990463257},{"id":"https://openalex.org/keywords/zona-fasciculata","display_name":"zona fasciculata","score":0.9290000200271606},{"id":"https://openalex.org/keywords/zona-reticularis","display_name":"zona reticularis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/adrenal-hypoplasia","display_name":"adrenal hypoplasia","score":0.9359999895095825},{"id":"https://openalex.org/keywords/prenatal-exposure","display_name":"prenatal exposure","score":0.5210000276565552},{"id":"https://openalex.org/keywords/postnatal-development","display_name":"postnatal development","score":0.9860000014305115},{"id":"https://openalex.org/keywords/adrenal-necrosis","display_name":"adrenal necrosis","score":0.6890000104904175},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.871999979019165}],"concepts":[{"id":"https://openalex.org/C137620995","wikidata":"https://www.wikidata.org/wiki/Q155769","display_name":"Wnt signaling pathway","level":3,"score":0.8256420493125916},{"id":"https://openalex.org/C40692019","wikidata":"https://www.wikidata.org/wiki/Q815547","display_name":"Morphogenesis","level":3,"score":0.8037117719650269},{"id":"https://openalex.org/C2777977426","wikidata":"https://www.wikidata.org/wiki/Q19065","display_name":"Adrenal cortex","level":2,"score":0.6782320737838745},{"id":"https://openalex.org/C46699223","wikidata":"https://www.wikidata.org/wiki/Q11078","display_name":"Endocrine system","level":3,"score":0.6370735764503479},{"id":"https://openalex.org/C171056886","wikidata":"https://www.wikidata.org/wiki/Q193119","display_name":"Regeneration (biology)","level":2,"score":0.6311150789260864},{"id":"https://openalex.org/C2780862370","wikidata":"https://www.wikidata.org/wiki/Q1138899","display_name":"Endocrine disruptor","level":4,"score":0.5523369312286377},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5113539099693298},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.4977581799030304},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49161893129348755},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4428275525569916},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.340548574924469},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.33359479904174805},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.25902456045150757},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.15631946921348572},{"id":"https://openalex.org/C71315377","wikidata":"https://www.wikidata.org/wiki/Q11364","display_name":"Hormone","level":2,"score":0.10789954662322998},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.09403127431869507}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1134/s1062359018060122","doi":"https://doi.org/10.1134/s1062359018060122","is_oa":false,"landing_page_url":"https://doi.org/10.1134/s1062359018060122","pdf_url":null,"source":{"id":"https://openalex.org/S4210230782","display_name":"Biology Bulletin","issn_l":"1062-3590","issn":["1062-3590","1608-3059"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320267","host_organization_name":"Pleiades Publishing","host_organization_lineage":["https://openalex.org/P4310320267","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Pleiades Publishing","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biology Bulletin","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.8048999905586243,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":21,"referenced_works":["https://openalex.org/W1967949545","https://openalex.org/W1968378264","https://openalex.org/W1986846926","https://openalex.org/W2007036394","https://openalex.org/W2012008624","https://openalex.org/W2023704290","https://openalex.org/W2027894846","https://openalex.org/W2029992626","https://openalex.org/W2032342884","https://openalex.org/W2053520113","https://openalex.org/W2071364196","https://openalex.org/W2097327668","https://openalex.org/W2100701799","https://openalex.org/W2105080125","https://openalex.org/W2119284420","https://openalex.org/W2122370310","https://openalex.org/W2136061252","https://openalex.org/W2140861044","https://openalex.org/W2141197851","https://openalex.org/W2165700542","https://openalex.org/W2166254889"],"related_works":["https://openalex.org/W2793921861","https://openalex.org/W4312307202","https://openalex.org/W2972250877","https://openalex.org/W4281671621","https://openalex.org/W3097179948","https://openalex.org/W3098241255","https://openalex.org/W3020010924","https://openalex.org/W4318777091","https://openalex.org/W3048720841","https://openalex.org/W3106283568"],"abstract_inverted_index":{"Abstract":[0],"This":[1,56],"study":[2],"is":[3],"focused":[4],"on":[5],"the":[6,9,18,25,37,46,59,62,66,69,75,83,96,99,105,110,121],"role":[7,60],"of":[8,17,36,45,53,61,68,82,89,98,107,109,120,124],"canonical":[10,54,100,111],"Wnt-signaling":[11,63,112],"pathway":[12,64,113],"in":[13,21,65,74,102,126],"morphogenesis":[14],"and":[15,32,86,92],"regeneration":[16],"adrenal":[19,76],"cortex":[20,77],"rats":[22],"exposed":[23],"to":[24,41,79],"endocrine":[26],"disruptor":[27],"dichlorodiphenyltrichloroethane":[28],"(DDT)":[29],"during":[30],"prenatal":[31],"postnatal":[33,127],"development.":[34,128],"Hypoplasia":[35],"zona":[38,47,70,84],"glomerulosa":[39],"and,":[40],"a":[42,118],"greater":[43],"extent,":[44],"reticularis":[48],"was":[49],"associated":[50],"with":[51],"suppression":[52],"Wnt.":[55],"data":[57],"indicates":[58],"development":[67],"reticularis.":[71],"Circulatory":[72],"disorders":[73],"led":[78],"focal":[80],"necrosis":[81],"fasciculata":[85],"subsequent":[87],"activation":[88,108],"cell":[90],"proliferation":[91],"regeneration,":[93],"mediated":[94],"by":[95],"inhibition":[97],"Wnt":[101],"it.":[103],"Thus,":[104],"disturbance":[106],"can":[114],"be":[115],"considered":[116],"as":[117],"mechanism":[119],"disrupting":[122],"effect":[123],"DDT":[125]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":5}],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2019-05-16T00:00:00"}