{"id":"https://openalex.org/W2944447368","doi":"https://doi.org/10.1007/s12640-019-00050-w","title":"Pifithrin-Alpha Reduces Methamphetamine Neurotoxicity in Cultured Dopaminergic Neurons","display_name":"Pifithrin-Alpha Reduces Methamphetamine Neurotoxicity in Cultured Dopaminergic Neurons","publication_year":2019,"publication_date":"2019-05-08","ids":{"openalex":"https://openalex.org/W2944447368","doi":"https://doi.org/10.1007/s12640-019-00050-w","mag":"2944447368","pmid":"https://pubmed.ncbi.nlm.nih.gov/31069753","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/12236268"},"language":"en","primary_location":{"id":"doi:10.1007/s12640-019-00050-w","doi":"https://doi.org/10.1007/s12640-019-00050-w","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12640-019-00050-w","pdf_url":null,"source":{"id":"https://openalex.org/S95346388","display_name":"Neurotoxicity Research","issn_l":"1029-8428","issn":["1029-8428","1476-3524"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurotoxicity Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12236268","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5003294295","display_name":"Yun\u2010Hsiang Chen","orcid":"https://orcid.org/0000-0002-2439-1080","observed_orcids":["https://orcid.org/0000-0002-2439-1080"]},"institutions":[{"id":"https://openalex.org/I114150738","display_name":"Fu Jen Catholic University","ror":"https://ror.org/04je98850","country_code":"TW","type":"education","lineage":["https://openalex.org/I114150738"]},{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Yun-Hsiang Chen","raw_affiliation_strings":["Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan","Department of Life Science, Fu-Jen Catholic University, New Taipei City, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan","institution_ids":["https://openalex.org/I165441096"]},{"raw_affiliation_string":"Department of Life Science, Fu-Jen Catholic University, New Taipei City, Taiwan","institution_ids":["https://openalex.org/I114150738"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082069599","display_name":"Eunkyung Cate Bae","orcid":"https://orcid.org/0000-0002-9169-716X","observed_orcids":["https://orcid.org/0000-0002-9169-716X"]},"institutions":[{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Eunkyung Bae","raw_affiliation_strings":["Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan","institution_ids":["https://openalex.org/I165441096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5023151684","display_name":"Hsi Chen","orcid":"https://orcid.org/0000-0002-6019-7760","observed_orcids":["https://orcid.org/0000-0002-6019-7760"]},"institutions":[{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Hsi Chen","raw_affiliation_strings":["Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan","institution_ids":["https://openalex.org/I165441096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011962611","display_name":"Seong\u2010Jin Yu","orcid":"https://orcid.org/0000-0001-7500-5883","observed_orcids":["https://orcid.org/0000-0001-7500-5883"]},"institutions":[{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]}],"countries":["TW"],"is_corresponding":false,"raw_author_name":"Seong-Jin Yu","raw_affiliation_strings":["Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan","institution_ids":["https://openalex.org/I165441096"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108880617","display_name":"Brandon K. Harvey","orcid":"https://orcid.org/0000-0002-4036-1383","observed_orcids":["https://orcid.org/0000-0002-4036-1383","https://orcid.org/0000-0002-7471-9937"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I1327069482","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I1327069482"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brandon K Harvey","raw_affiliation_strings":["Molecular Mechanisms of Cellular Stress and Inflammation Unit, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Molecular Mechanisms of Cellular Stress and Inflammation Unit, Intramural Research Program, National Institute on Drug Abuse, NIH, Baltimore, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I1327069482"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056649584","display_name":"Nigel H. Greig","orcid":"https://orcid.org/0000-0002-3032-1468","observed_orcids":["https://orcid.org/0000-0002-3032-1468"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210136897","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nigel H Greig","raw_affiliation_strings":["Translational Gerontology Branch, Intramural Research Program, National Institute of Aging, NIH, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Translational Gerontology Branch, Intramural Research Program, National Institute of Aging, NIH, Baltimore, MD, USA","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210136897"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100377600","display_name":"Yun Wang","orcid":"https://orcid.org/0000-0001-7146-8290","observed_orcids":["https://orcid.org/0000-0001-7146-8290"]},"institutions":[{"id":"https://openalex.org/I165441096","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29","country_code":"TW","type":"nonprofit","lineage":["https://openalex.org/I165441096"]}],"countries":["TW"],"is_corresponding":true,"raw_author_name":"Yun Wang","raw_affiliation_strings":["Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan. ywang@nhri.org.tw","Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan. ywang@nhri.org.tw","institution_ids":["https://openalex.org/I165441096"]},{"raw_affiliation_string":"Center for Neuropsychiatric Research, National Health Research Institutes, Zhunan, Taiwan","institution_ids":["https://openalex.org/I165441096"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5100377600"],"corresponding_institution_ids":["https://openalex.org/I165441096"],"apc_list":{"value":3760,"currency":"USD","value_usd":3760},"apc_paid":null,"fwci":1.6868,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.82427462,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":"36","issue":"2","first_page":"347","last_page":"356"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.7113999724388123,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments","score":0.7113999724388123,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11150","display_name":"Endoplasmic Reticulum Stress and Disease","score":0.20999999344348907,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.01759999990463257,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pifithrin-alpha","display_name":"pifithrin-alpha","score":0.9739999771118164},{"id":"https://openalex.org/keywords/methamphetamine","display_name":"methamphetamine","score":0.8159999847412109},{"id":"https://openalex.org/keywords/dopaminergic-neurons","display_name":"dopaminergic neurons","score":0.9210000038146973},{"id":"https://openalex.org/keywords/neuroprotection","display_name":"neuroprotection","score":0.875},{"id":"https://openalex.org/keywords/p53","display_name":"p53","score":0.8880000114440918},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.8799999952316284},{"id":"https://openalex.org/keywords/endoplasmic-reticulum-stress","display_name":"endoplasmic reticulum stress","score":0.9520000219345093},{"id":"https://openalex.org/keywords/thapsigargin","display_name":"thapsigargin","score":0.9359999895095825},{"id":"https://openalex.org/keywords/chop","display_name":"CHOP","score":0.9399999976158142},{"id":"https://openalex.org/keywords/neurodegeneration","display_name":"neurodegeneration","score":0.6819999814033508},{"id":"https://openalex.org/keywords/tyrosine-hydroxylase","display_name":"tyrosine hydroxylase","score":0.8709999918937683},{"id":"https://openalex.org/keywords/sh-sy5y-cells","display_name":"SH-SY5Y cells","score":0.8009999990463257},{"id":"https://openalex.org/keywords/gaussia-luciferase","display_name":"Gaussia luciferase","score":0.7269999980926514}],"concepts":[{"id":"https://openalex.org/C2780114369","wikidata":"https://www.wikidata.org/wiki/Q6823535","display_name":"Meth-","level":5,"score":0.8223927617073059},{"id":"https://openalex.org/C137183658","wikidata":"https://www.wikidata.org/wiki/Q461076","display_name":"Dopaminergic","level":3,"score":0.6811899542808533},{"id":"https://openalex.org/C2780376393","wikidata":"https://www.wikidata.org/wiki/Q191924","display_name":"Methamphetamine","level":2,"score":0.6664140820503235},{"id":"https://openalex.org/C2779491297","wikidata":"https://www.wikidata.org/wiki/Q3338704","display_name":"Neurotoxicity","level":3,"score":0.6491236686706543},{"id":"https://openalex.org/C25498285","wikidata":"https://www.wikidata.org/wiki/Q1981368","display_name":"Neuroprotection","level":2,"score":0.5765314698219299},{"id":"https://openalex.org/C196795494","wikidata":"https://www.wikidata.org/wiki/Q1624817","display_name":"TUNEL assay","level":3,"score":0.48160693049430847},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.46049124002456665},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.45204076170921326},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3695434629917145},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.35149431228637695},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.32275646924972534},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.3189581036567688},{"id":"https://openalex.org/C513476851","wikidata":"https://www.wikidata.org/wiki/Q170304","display_name":"Dopamine","level":2,"score":0.2399366796016693},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19524937868118286},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.10267671942710876},{"id":"https://openalex.org/C2779989194","wikidata":"https://www.wikidata.org/wiki/Q343016","display_name":"Acrylate","level":4,"score":0.0},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C166940927","wikidata":"https://www.wikidata.org/wiki/Q178827","display_name":"Monomer","level":3,"score":0.0}],"mesh":[{"descriptor_ui":"D000697","descriptor_name":"Central Nervous System Stimulants","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002478","descriptor_name":"Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008694","descriptor_name":"Methamphetamine","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014050","descriptor_name":"Toluene","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D014050","descriptor_name":"Toluene","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D052160","descriptor_name":"Benzothiazoles","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D059290","descriptor_name":"Dopaminergic Neurons","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D059290","descriptor_name":"Dopaminergic Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D059290","descriptor_name":"Dopaminergic Neurons","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D059865","descriptor_name":"Endoplasmic Reticulum Stress","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D059865","descriptor_name":"Endoplasmic Reticulum Stress","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1007/s12640-019-00050-w","doi":"https://doi.org/10.1007/s12640-019-00050-w","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s12640-019-00050-w","pdf_url":null,"source":{"id":"https://openalex.org/S95346388","display_name":"Neurotoxicity Research","issn_l":"1029-8428","issn":["1029-8428","1476-3524"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurotoxicity Research","raw_type":"journal-article"},{"id":"pmid:31069753","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31069753","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Neurotoxicity research","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:12236268","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12236268","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Neurotox Res","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:12236268","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/12236268","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Neurotox Res","raw_type":"Text"},"sustainable_development_goals":[{"score":0.98580002784729,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1766269420","display_name":null,"funder_award_id":"105-2320-B-400-012-MY3","funder_id":"https://openalex.org/F4320309618","funder_display_name":"Ministry of Science and Technology"},{"id":"https://openalex.org/G4929521004","display_name":"Neuroprotective and regenerative effects of small molecules and their receptors","funder_award_id":"ZIADA000461","funder_id":"https://openalex.org/F4320337347","funder_display_name":"National Institute on Drug Abuse"},{"id":"https://openalex.org/G5053974381","display_name":"Design And Development Of Experimental Therapeutics","funder_award_id":"Z01AG000311","funder_id":"https://openalex.org/F4320337337","funder_display_name":"National Institute on Aging"},{"id":"https://openalex.org/G6519718130","display_name":null,"funder_award_id":"107-2314-B-030-009","funder_id":"https://openalex.org/F4320309618","funder_display_name":"Ministry of Science and Technology"}],"funders":[{"id":"https://openalex.org/F4320309618","display_name":"Ministry of Science and Technology","ror":"https://ror.org/02b207r52"},{"id":"https://openalex.org/F4320322845","display_name":"National Health Research Institutes","ror":"https://ror.org/02r6fpx29"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","ror":"https://ror.org/049v75w11"},{"id":"https://openalex.org/F4320337347","display_name":"National Institute on Drug Abuse","ror":"https://ror.org/00fq5cm18"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":53,"referenced_works":["https://openalex.org/W1510888814","https://openalex.org/W1596222665","https://openalex.org/W1969455851","https://openalex.org/W1970249544","https://openalex.org/W1975690985","https://openalex.org/W1977340768","https://openalex.org/W1977888667","https://openalex.org/W1979947456","https://openalex.org/W1987742034","https://openalex.org/W1989017430","https://openalex.org/W1989511952","https://openalex.org/W1992549938","https://openalex.org/W1999483432","https://openalex.org/W2003320922","https://openalex.org/W2004994982","https://openalex.org/W2007614811","https://openalex.org/W2009924110","https://openalex.org/W2015620683","https://openalex.org/W2022762621","https://openalex.org/W2030393531","https://openalex.org/W2032338900","https://openalex.org/W2033543666","https://openalex.org/W2034685111","https://openalex.org/W2043313694","https://openalex.org/W2060618478","https://openalex.org/W2060988288","https://openalex.org/W2063131548","https://openalex.org/W2073173679","https://openalex.org/W2087243728","https://openalex.org/W2092416152","https://openalex.org/W2093590078","https://openalex.org/W2100347985","https://openalex.org/W2102367553","https://openalex.org/W2113880766","https://openalex.org/W2126679757","https://openalex.org/W2138274734","https://openalex.org/W2144176813","https://openalex.org/W2144994572","https://openalex.org/W2155353396","https://openalex.org/W2172495856","https://openalex.org/W2327365351","https://openalex.org/W2395446774","https://openalex.org/W2441007921","https://openalex.org/W2527503499","https://openalex.org/W2602473441","https://openalex.org/W2606481626","https://openalex.org/W2625282817","https://openalex.org/W2754599293","https://openalex.org/W2767326431","https://openalex.org/W2781977913","https://openalex.org/W2791073739","https://openalex.org/W2811434135","https://openalex.org/W2900789602"],"related_works":["https://openalex.org/W2602473441","https://openalex.org/W1977888667","https://openalex.org/W1977340768","https://openalex.org/W2130014240","https://openalex.org/W1658677077","https://openalex.org/W2149518951","https://openalex.org/W2069068765","https://openalex.org/W4406353983","https://openalex.org/W3184393216","https://openalex.org/W7132839415"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-05-16T00:00:00"}