{"id":"https://openalex.org/W2943417756","doi":"https://doi.org/10.1016/j.tice.2019.04.010","title":"Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model","display_name":"Pazopanib regresses a doxorubicin-resistant synovial sarcoma in a patient-derived orthotopic xenograft mouse model","publication_year":2019,"publication_date":"2019-05-03","ids":{"openalex":"https://openalex.org/W2943417756","doi":"https://doi.org/10.1016/j.tice.2019.04.010","mag":"2943417756","pmid":"https://pubmed.ncbi.nlm.nih.gov/31133237"},"language":"en","primary_location":{"id":"doi:10.1016/j.tice.2019.04.010","doi":"https://doi.org/10.1016/j.tice.2019.04.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tice.2019.04.010","pdf_url":null,"source":{"id":"https://openalex.org/S165572755","display_name":"Tissue and Cell","issn_l":"0040-8166","issn":["0040-8166","1532-3072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue and Cell","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5081080411","display_name":"Kentaro Igarashi","orcid":"https://orcid.org/0000-0003-2278-1736","observed_orcids":["https://orcid.org/0000-0003-2278-1736"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210121314","display_name":"AntiCancer (United States)","ror":"https://ror.org/02pp1v282","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121314"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"Kentaro Igarashi","raw_affiliation_strings":["AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA; Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","AntiCancer, Inc., San Diego, CA, USA","Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","Department of Surgery, University of California, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA; Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","institution_ids":["https://openalex.org/I10091056","https://openalex.org/I36258959","https://openalex.org/I4210121314"]},{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA","institution_ids":["https://openalex.org/I4210121314"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","institution_ids":["https://openalex.org/I10091056"]},{"raw_affiliation_string":"Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110514735","display_name":"Kei Kawaguchi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210121314","display_name":"AntiCancer (United States)","ror":"https://ror.org/02pp1v282","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121314"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kei Kawaguchi","raw_affiliation_strings":["AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA","AntiCancer, Inc., San Diego, CA, USA","Department of Surgery, University of California, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959","https://openalex.org/I4210121314"]},{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA","institution_ids":["https://openalex.org/I4210121314"]},{"raw_affiliation_string":"Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017915063","display_name":"Tasuku Kiyuna","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210121314","display_name":"AntiCancer (United States)","ror":"https://ror.org/02pp1v282","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121314"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tasuku Kiyuna","raw_affiliation_strings":["AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA","AntiCancer, Inc., San Diego, CA, USA","Department of Surgery, University of California, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959","https://openalex.org/I4210121314"]},{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA","institution_ids":["https://openalex.org/I4210121314"]},{"raw_affiliation_string":"Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5084841997","display_name":"Kentaro Miyake","orcid":"https://orcid.org/0000-0002-4680-4317","observed_orcids":["https://orcid.org/0000-0002-4680-4317"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210121314","display_name":"AntiCancer (United States)","ror":"https://ror.org/02pp1v282","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121314"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kentaro Miyake","raw_affiliation_strings":["AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA","AntiCancer, Inc., San Diego, CA, USA","Department of Surgery, University of California, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959","https://openalex.org/I4210121314"]},{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA","institution_ids":["https://openalex.org/I4210121314"]},{"raw_affiliation_string":"Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089307192","display_name":"Masuyo Miyake","orcid":"https://orcid.org/0000-0003-4128-732X","observed_orcids":["https://orcid.org/0000-0003-4128-732X"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210121314","display_name":"AntiCancer (United States)","ror":"https://ror.org/02pp1v282","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121314"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Masuyo Miyake","raw_affiliation_strings":["AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA","AntiCancer, Inc., San Diego, CA, USA","Department of Surgery, University of California, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959","https://openalex.org/I4210121314"]},{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA","institution_ids":["https://openalex.org/I4210121314"]},{"raw_affiliation_string":"Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002607014","display_name":"Scott D. Nelson","orcid":"https://orcid.org/0000-0002-8435-5065","observed_orcids":["https://orcid.org/0000-0002-8435-5065"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Scott D. Nelson","raw_affiliation_strings":["Department of Pathology, University of California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047314223","display_name":"Tara A. Russell","orcid":"https://orcid.org/0000-0002-3912-3601","observed_orcids":["https://orcid.org/0000-0002-3912-3601"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tara A. Russell","raw_affiliation_strings":["Division of Surgical Oncology, University of California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Surgical Oncology, University of California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070052371","display_name":"Sarah Dry","orcid":"https://orcid.org/0000-0002-1858-5225","observed_orcids":["https://orcid.org/0000-0002-1858-5225"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sarah M. Dry","raw_affiliation_strings":["Department of Pathology, University of California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100326026","display_name":"Yunfeng Li","orcid":"https://orcid.org/0000-0002-6520-8561","observed_orcids":["https://orcid.org/0000-0002-6520-8561"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yunfeng Li","raw_affiliation_strings":["Department of Pathology, University of California, Los Angeles, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of California, Los Angeles, CA, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032191719","display_name":"Norio Yamamoto","orcid":"https://orcid.org/0000-0002-7250-625X","observed_orcids":["https://orcid.org/0000-0002-7250-625X"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Norio Yamamoto","raw_affiliation_strings":["Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028483263","display_name":"Katsuhiro Hayashi","orcid":"https://orcid.org/0000-0001-8665-2154","observed_orcids":["https://orcid.org/0000-0001-8665-2154"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Katsuhiro Hayashi","raw_affiliation_strings":["Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101523025","display_name":"Hiroaki Kimura","orcid":"https://orcid.org/0000-0003-2145-8726","observed_orcids":["https://orcid.org/0000-0003-2145-8726"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hiroaki Kimura","raw_affiliation_strings":["Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010692199","display_name":"Shinji Miwa","orcid":"https://orcid.org/0000-0002-5962-8287","observed_orcids":["https://orcid.org/0000-0002-5962-8287"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shinji Miwa","raw_affiliation_strings":["Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025137772","display_name":"Takashi Higuchi","orcid":"https://orcid.org/0000-0002-7489-1657","observed_orcids":["https://orcid.org/0000-0002-7489-1657"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]},{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210121314","display_name":"AntiCancer (United States)","ror":"https://ror.org/02pp1v282","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121314"]}],"countries":["JP","US"],"is_corresponding":false,"raw_author_name":"Takashi Higuchi","raw_affiliation_strings":["AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA; Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","AntiCancer, Inc., San Diego, CA, USA","Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","Department of Surgery, University of California, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA; Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","institution_ids":["https://openalex.org/I10091056","https://openalex.org/I36258959","https://openalex.org/I4210121314"]},{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA","institution_ids":["https://openalex.org/I4210121314"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","institution_ids":["https://openalex.org/I10091056"]},{"raw_affiliation_string":"Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059834789","display_name":"Shree Ram Singh","orcid":"https://orcid.org/0000-0001-6545-583X","observed_orcids":["https://orcid.org/0000-0001-6545-583X"]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4210140884","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210140884"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Shree Ram Singh","raw_affiliation_strings":["Basic Research Laboratory, National Cancer Institute, Frederick, MD, USA. Electronic address: singhshr@mail.nih.gov","Basic Research Laboratory, National Cancer Institute, Frederick, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Basic Research Laboratory, National Cancer Institute, Frederick, MD, USA. Electronic address: singhshr@mail.nih.gov","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"raw_affiliation_string":"Basic Research Laboratory, National Cancer Institute, Frederick, MD, USA","institution_ids":["https://openalex.org/I4210140884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056400625","display_name":"Hiroyuki Tsuchiya","orcid":"https://orcid.org/0000-0003-0730-7921","observed_orcids":["https://orcid.org/0000-0003-0730-7921"]},"institutions":[{"id":"https://openalex.org/I10091056","display_name":"Kanazawa University","ror":"https://ror.org/02hwp6a56","country_code":"JP","type":"education","lineage":["https://openalex.org/I10091056"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Hiroyuki Tsuchiya","raw_affiliation_strings":["Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan. Electronic address: tsuchi@med.kanazawa-u.ac.jp","Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan. Electronic address: tsuchi@med.kanazawa-u.ac.jp","institution_ids":["https://openalex.org/I10091056"]},{"raw_affiliation_string":"Department of Orthopaedic Surgery, Kanazawa University, Kanazawa, Japan","institution_ids":["https://openalex.org/I10091056"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040819666","display_name":"Robert M. Hoffman","orcid":"https://orcid.org/0000-0002-0049-0041","observed_orcids":["https://orcid.org/0000-0002-0049-0041"]},"institutions":[{"id":"https://openalex.org/I36258959","display_name":"University of California San Diego","ror":"https://ror.org/0168r3w48","country_code":"US","type":"education","lineage":["https://openalex.org/I36258959"]},{"id":"https://openalex.org/I4210121314","display_name":"AntiCancer (United States)","ror":"https://ror.org/02pp1v282","country_code":"US","type":"company","lineage":["https://openalex.org/I4210121314"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Robert M. Hoffman","raw_affiliation_strings":["AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA. Electronic address: all@anticancer.com","AntiCancer, Inc., San Diego, CA, USA","Department of Surgery, University of California, San Diego, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA; Department of Surgery, University of California, San Diego, CA, USA. Electronic address: all@anticancer.com","institution_ids":["https://openalex.org/I36258959","https://openalex.org/I4210121314"]},{"raw_affiliation_string":"AntiCancer, Inc., San Diego, CA, USA","institution_ids":["https://openalex.org/I4210121314"]},{"raw_affiliation_string":"Department of Surgery, University of California, San Diego, CA, USA","institution_ids":["https://openalex.org/I36258959"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5040819666","https://openalex.org/A5056400625","https://openalex.org/A5059834789"],"corresponding_institution_ids":["https://openalex.org/I10091056","https://openalex.org/I36258959","https://openalex.org/I4210121314","https://openalex.org/I4210130649","https://openalex.org/I4210140884"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.5508,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.6834689,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":95},"biblio":{"volume":"58","issue":null,"first_page":"107","last_page":"111"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11638","display_name":"Cardiac tumors and thrombi","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12278","display_name":"Vascular Tumors and Angiosarcomas","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/synovial-sarcoma","display_name":"synovial sarcoma","score":0.9959999918937683},{"id":"https://openalex.org/keywords/pazopanib","display_name":"pazopanib","score":0.9980000257492065},{"id":"https://openalex.org/keywords/doxorubicin-resistance","display_name":"doxorubicin resistance","score":0.9959999918937683},{"id":"https://openalex.org/keywords/patient-derived-orthotopic-xenograft","display_name":"patient-derived orthotopic xenograft","score":0.9710000157356262},{"id":"https://openalex.org/keywords/soft-tissue-sarcoma","display_name":"soft tissue sarcoma","score":0.9660000205039978},{"id":"https://openalex.org/keywords/temozolomide","display_name":"temozolomide","score":0.8579999804496765},{"id":"https://openalex.org/keywords/gemcitabine","display_name":"gemcitabine","score":0.878000020980835},{"id":"https://openalex.org/keywords/docetaxel","display_name":"docetaxel","score":0.9950000047683716},{"id":"https://openalex.org/keywords/tumor-regression","display_name":"tumor regression","score":0.7490000128746033},{"id":"https://openalex.org/keywords/precision-oncology","display_name":"precision oncology","score":0.5490000247955322},{"id":"https://openalex.org/keywords/lower-extremity-sarcoma","display_name":"lower extremity sarcoma","score":0.6430000066757202}],"concepts":[{"id":"https://openalex.org/C2781303535","wikidata":"https://www.wikidata.org/wiki/Q18936","display_name":"Doxorubicin","level":3,"score":0.689423680305481},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.6181469559669495},{"id":"https://openalex.org/C2776910622","wikidata":"https://www.wikidata.org/wiki/Q2619315","display_name":"Synovial sarcoma","level":3,"score":0.5782095789909363},{"id":"https://openalex.org/C2778439243","wikidata":"https://www.wikidata.org/wiki/Q7157043","display_name":"Pazopanib","level":4,"score":0.5688672661781311},{"id":"https://openalex.org/C2780258809","wikidata":"https://www.wikidata.org/wiki/Q414143","display_name":"Gemcitabine","level":3,"score":0.5352523922920227},{"id":"https://openalex.org/C2778629024","wikidata":"https://www.wikidata.org/wiki/Q720020","display_name":"Soft tissue sarcoma","level":3,"score":0.5058474540710449},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5016329288482666},{"id":"https://openalex.org/C2777389519","wikidata":"https://www.wikidata.org/wiki/Q425088","display_name":"Temozolomide","level":3,"score":0.494247704744339},{"id":"https://openalex.org/C2781190966","wikidata":"https://www.wikidata.org/wiki/Q420436","display_name":"Docetaxel","level":3,"score":0.46434053778648376},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.44577479362487793},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.4217413663864136},{"id":"https://openalex.org/C2776999253","wikidata":"https://www.wikidata.org/wiki/Q1304270","display_name":"Combination therapy","level":2,"score":0.4140288829803467},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39282259345054626},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3867476284503937},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.3826856017112732},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.36683425307273865},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3508634865283966},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.29435479640960693},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.23812273144721985},{"id":"https://openalex.org/C2779490328","wikidata":"https://www.wikidata.org/wiki/Q417542","display_name":"Sunitinib","level":3,"score":0.0932111144065857}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004317","descriptor_name":"Doxorubicin","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007191","descriptor_name":"Indazoles","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011743","descriptor_name":"Pyrimidines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013449","descriptor_name":"Sulfonamides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D013584","descriptor_name":"Sarcoma, Synovial","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D013584","descriptor_name":"Sarcoma, Synovial","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013584","descriptor_name":"Sarcoma, Synovial","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D019008","descriptor_name":"Drug Resistance, Neoplasm","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D023041","descriptor_name":"Xenograft Model Antitumor Assays","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.tice.2019.04.010","doi":"https://doi.org/10.1016/j.tice.2019.04.010","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.tice.2019.04.010","pdf_url":null,"source":{"id":"https://openalex.org/S165572755","display_name":"Tissue and Cell","issn_l":"0040-8166","issn":["0040-8166","1532-3072"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue and Cell","raw_type":"journal-article"},{"id":"pmid:31133237","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31133237","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tissue & cell","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2428545338","display_name":"Investigation for mechanism of metastasis using molecular imaging","funder_award_id":"19K09571","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":46,"referenced_works":["https://openalex.org/W249545773","https://openalex.org/W913293939","https://openalex.org/W1935829965","https://openalex.org/W1964513792","https://openalex.org/W1969705513","https://openalex.org/W1977144004","https://openalex.org/W1988505549","https://openalex.org/W1993570465","https://openalex.org/W1993866317","https://openalex.org/W1998139955","https://openalex.org/W2003278910","https://openalex.org/W2028701135","https://openalex.org/W2035387891","https://openalex.org/W2038208403","https://openalex.org/W2048248253","https://openalex.org/W2052625497","https://openalex.org/W2061292442","https://openalex.org/W2088018126","https://openalex.org/W2101776780","https://openalex.org/W2106478689","https://openalex.org/W2107230638","https://openalex.org/W2211516346","https://openalex.org/W2306887830","https://openalex.org/W2339055665","https://openalex.org/W2342246138","https://openalex.org/W2408339495","https://openalex.org/W2419037363","https://openalex.org/W2550513787","https://openalex.org/W2559651736","https://openalex.org/W2587201730","https://openalex.org/W2606449738","https://openalex.org/W2612978847","https://openalex.org/W2725950961","https://openalex.org/W2744612300","https://openalex.org/W2773499080","https://openalex.org/W2795289331","https://openalex.org/W2796729556","https://openalex.org/W2800991425","https://openalex.org/W2803924465","https://openalex.org/W2804729741","https://openalex.org/W2809668133","https://openalex.org/W2887819312","https://openalex.org/W2889504957","https://openalex.org/W2894042521","https://openalex.org/W2905230616","https://openalex.org/W2921493122"],"related_works":["https://openalex.org/W2587201730","https://openalex.org/W2796729556","https://openalex.org/W6910506488","https://openalex.org/W2800991425","https://openalex.org/W2804729741","https://openalex.org/W2981091896","https://openalex.org/W2972438127","https://openalex.org/W4401514812","https://openalex.org/W3215268933","https://openalex.org/W3170241367"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-05-09T00:00:00"}