{"id":"https://openalex.org/W2943301397","doi":"https://doi.org/10.1016/j.molstruc.2019.04.119","title":"Spectroscopic exploration of binding of new imidazolium-based palladium(II) saldach complexes with CT-DNA as anticancer agents against HER2/neu overexpression","display_name":"Spectroscopic exploration of binding of new imidazolium-based palladium(II) saldach complexes with CT-DNA as anticancer agents against HER2/neu overexpression","publication_year":2019,"publication_date":"2019-04-29","ids":{"openalex":"https://openalex.org/W2943301397","doi":"https://doi.org/10.1016/j.molstruc.2019.04.119","mag":"2943301397"},"language":"en","primary_location":{"id":"doi:10.1016/j.molstruc.2019.04.119","doi":"https://doi.org/10.1016/j.molstruc.2019.04.119","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molstruc.2019.04.119","pdf_url":null,"source":{"id":"https://openalex.org/S203479135","display_name":"Journal of Molecular Structure","issn_l":"0022-2860","issn":["0022-2860","1872-8014"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Structure","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005764434","display_name":"Mohammad Yahya Alfaifi","orcid":"https://orcid.org/0000-0003-4310-3539","observed_orcids":["https://orcid.org/0000-0003-4310-3539"]},"institutions":[{"id":"https://openalex.org/I82952536","display_name":"King Khalid University","ror":"https://ror.org/052kwzs30","country_code":"SA","type":"education","lineage":["https://openalex.org/I82952536"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Mohammad Y. Alfaifi","raw_affiliation_strings":["Biology Department, Faculty of Science, King Khalid University, 9004, Abha, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Faculty of Science, King Khalid University, 9004, Abha, Saudi Arabia","institution_ids":["https://openalex.org/I82952536"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009503447","display_name":"Serag Eldin I. Elbehairi","orcid":"https://orcid.org/0000-0003-4680-3215","observed_orcids":["https://orcid.org/0000-0003-4680-3215"]},"institutions":[{"id":"https://openalex.org/I82952536","display_name":"King Khalid University","ror":"https://ror.org/052kwzs30","country_code":"SA","type":"education","lineage":["https://openalex.org/I82952536"]}],"countries":["SA"],"is_corresponding":false,"raw_author_name":"Serag Eldin I. Elbehairi","raw_affiliation_strings":["Biology Department, Faculty of Science, King Khalid University, 9004, Abha, Saudi Arabia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, Faculty of Science, King Khalid University, 9004, Abha, Saudi Arabia","institution_ids":["https://openalex.org/I82952536"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025888829","display_name":"Hani S. Hafez","orcid":"https://orcid.org/0000-0002-8899-9941","observed_orcids":["https://orcid.org/0000-0002-8899-9941"]},"institutions":[{"id":"https://openalex.org/I130009713","display_name":"Suez University","ror":"https://ror.org/00ndhrx30","country_code":"EG","type":"education","lineage":["https://openalex.org/I130009713"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Hani S. Hafez","raw_affiliation_strings":["Faculty of Science, Zoology Department, Suez University, 43533, Suez, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Science, Zoology Department, Suez University, 43533, Suez, Egypt","institution_ids":["https://openalex.org/I130009713"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5008468578","display_name":"Reda F.M. Elshaarawy","orcid":"https://orcid.org/0000-0003-2100-8928","observed_orcids":["https://orcid.org/0000-0003-2100-8928","https://orcid.org/0000-0002-7654-3234"]},"institutions":[{"id":"https://openalex.org/I130009713","display_name":"Suez University","ror":"https://ror.org/00ndhrx30","country_code":"EG","type":"education","lineage":["https://openalex.org/I130009713"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Reda F.M. Elshaarawy","raw_affiliation_strings":["Faculty of Science, Chemistry Department, Suez University, 43533, Suez, Egypt"],"raw_orcid":"https://orcid.org/0000-0003-2100-8928","affiliations":[{"raw_affiliation_string":"Faculty of Science, Chemistry Department, Suez University, 43533, Suez, Egypt","institution_ids":["https://openalex.org/I130009713"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5008468578"],"corresponding_institution_ids":["https://openalex.org/I130009713"],"apc_list":{"value":2600,"currency":"USD","value_usd":2600},"apc_paid":null,"fwci":1.6849,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.85289227,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":95,"max":98},"biblio":{"volume":"1191","issue":null,"first_page":"118","last_page":"128"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10274","display_name":"Heterocyclic Compound Synthesis and Bioactivity","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11746","display_name":"Inorganic and Organometallic Chemistry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/palladium-ii-complexes","display_name":"palladium(II) complexes","score":0.9819999933242798},{"id":"https://openalex.org/keywords/ct-dna-binding","display_name":"CT-DNA binding","score":0.7990000247955322},{"id":"https://openalex.org/keywords/dna-intercalation","display_name":"DNA intercalation","score":0.8199999928474426},{"id":"https://openalex.org/keywords/anticancer-agents","display_name":"anticancer agents","score":0.8460000157356262},{"id":"https://openalex.org/keywords/her2-overexpression","display_name":"HER2 overexpression","score":0.8870000243186951},{"id":"https://openalex.org/keywords/breast-adenocarcinoma","display_name":"breast adenocarcinoma","score":0.9549999833106995},{"id":"https://openalex.org/keywords/mcf-7-cells","display_name":"MCF-7 cells","score":0.9909999966621399},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8730000257492065},{"id":"https://openalex.org/keywords/p53-expression","display_name":"p53 expression","score":0.7329999804496765},{"id":"https://openalex.org/keywords/tnf-alpha","display_name":"TNF-\u03b1","score":0.8429999947547913},{"id":"https://openalex.org/keywords/dna-replication-inhibition","display_name":"DNA replication inhibition","score":0.41999998688697815},{"id":"https://openalex.org/keywords/covalent-dna-binding","display_name":"covalent DNA binding","score":0.6050000190734863}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.9030908346176147},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.6443887948989868},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.5994331240653992},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5961126685142517},{"id":"https://openalex.org/C137824038","wikidata":"https://www.wikidata.org/wiki/Q175562","display_name":"Intercalation (chemistry)","level":2,"score":0.5656750798225403},{"id":"https://openalex.org/C112887158","wikidata":"https://www.wikidata.org/wiki/Q169324","display_name":"Hydrogen bond","level":3,"score":0.5084092020988464},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.4958740174770355},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.48297253251075745},{"id":"https://openalex.org/C2777752497","wikidata":"https://www.wikidata.org/wiki/Q286779","display_name":"IC50","level":3,"score":0.46679195761680603},{"id":"https://openalex.org/C127561419","wikidata":"https://www.wikidata.org/wiki/Q224527","display_name":"Downregulation and upregulation","level":3,"score":0.4624521732330322},{"id":"https://openalex.org/C502130503","wikidata":"https://www.wikidata.org/wiki/Q1089","display_name":"Palladium","level":3,"score":0.428549587726593},{"id":"https://openalex.org/C17991360","wikidata":"https://www.wikidata.org/wiki/Q21173843","display_name":"Tumor necrosis factor alpha","level":2,"score":0.41875195503234863},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.346067875623703},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.24557074904441833},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2180284559726715},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13254544138908386},{"id":"https://openalex.org/C32909587","wikidata":"https://www.wikidata.org/wiki/Q11369","display_name":"Molecule","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.0},{"id":"https://openalex.org/C179104552","wikidata":"https://www.wikidata.org/wiki/Q11165","display_name":"Inorganic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.molstruc.2019.04.119","doi":"https://doi.org/10.1016/j.molstruc.2019.04.119","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.molstruc.2019.04.119","pdf_url":null,"source":{"id":"https://openalex.org/S203479135","display_name":"Journal of Molecular Structure","issn_l":"0022-2860","issn":["0022-2860","1872-8014"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-d","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Molecular Structure","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8999999761581421,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":71,"referenced_works":["https://openalex.org/W112768673","https://openalex.org/W1596365788","https://openalex.org/W1635322256","https://openalex.org/W1914501114","https://openalex.org/W1965779968","https://openalex.org/W1976608620","https://openalex.org/W1984274637","https://openalex.org/W1987244025","https://openalex.org/W1987993156","https://openalex.org/W1993676677","https://openalex.org/W1997338710","https://openalex.org/W1997803538","https://openalex.org/W2004786678","https://openalex.org/W2005723165","https://openalex.org/W2007251292","https://openalex.org/W2010282657","https://openalex.org/W2010321797","https://openalex.org/W2012572051","https://openalex.org/W2019932858","https://openalex.org/W2023339936","https://openalex.org/W2026908726","https://openalex.org/W2028387622","https://openalex.org/W2033252607","https://openalex.org/W2036098386","https://openalex.org/W2038822441","https://openalex.org/W2043711125","https://openalex.org/W2044545507","https://openalex.org/W2044851985","https://openalex.org/W2051058983","https://openalex.org/W2053849461","https://openalex.org/W2054862649","https://openalex.org/W2058693778","https://openalex.org/W2064047613","https://openalex.org/W2072895129","https://openalex.org/W2074544041","https://openalex.org/W2076951953","https://openalex.org/W2078160716","https://openalex.org/W2081002016","https://openalex.org/W2089096593","https://openalex.org/W2092229345","https://openalex.org/W2095156669","https://openalex.org/W2095454751","https://openalex.org/W2099473254","https://openalex.org/W2099925103","https://openalex.org/W2114918609","https://openalex.org/W2117744900","https://openalex.org/W2120178047","https://openalex.org/W2138885705","https://openalex.org/W2141393790","https://openalex.org/W2144737008","https://openalex.org/W2151273858","https://openalex.org/W2151605875","https://openalex.org/W2156817521","https://openalex.org/W2159363679","https://openalex.org/W2159367197","https://openalex.org/W2394931631","https://openalex.org/W2413369851","https://openalex.org/W2510518458","https://openalex.org/W2579923564","https://openalex.org/W2580018907","https://openalex.org/W2588892681","https://openalex.org/W2591580144","https://openalex.org/W2769071100","https://openalex.org/W2794148927","https://openalex.org/W2802149049","https://openalex.org/W2883340014","https://openalex.org/W2884311287","https://openalex.org/W6604619464","https://openalex.org/W6636859827","https://openalex.org/W6644629458","https://openalex.org/W6682287986"],"related_works":["https://openalex.org/W2729866620","https://openalex.org/W2066105236","https://openalex.org/W6977470174","https://openalex.org/W6939637870","https://openalex.org/W1483279765","https://openalex.org/W2911616405","https://openalex.org/W4411059539","https://openalex.org/W4362465521","https://openalex.org/W4416731019","https://openalex.org/W2550737316"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-05-09T00:00:00"}