{"id":"https://openalex.org/W29430357","doi":null,"title":"Activated skin mast cells are involved in murine hair follicle regression (catagen).","display_name":"Activated skin mast cells are involved in murine hair follicle regression (catagen).","publication_year":1997,"publication_date":"1997-10-01","ids":{"openalex":"https://openalex.org/W29430357","mag":"29430357","pmid":"https://pubmed.ncbi.nlm.nih.gov/9354767"},"language":"en","primary_location":{"id":"pmid:9354767","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9354767","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Laboratory investigation; a journal of technical methods and pathology","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5091156366","display_name":"Marcus Maurer","orcid":"https://orcid.org/0000-0002-4121-481X","observed_orcids":["https://orcid.org/0000-0002-4121-481X"]},"institutions":[{"id":"https://openalex.org/I39343248","display_name":"Humboldt-Universit\u00e4t zu Berlin","ror":"https://ror.org/01hcx6992","country_code":"DE","type":"education","lineage":["https://openalex.org/I39343248"]},{"id":"https://openalex.org/I7877124","display_name":"Charit\u00e9 \u2013 Universit\u00e4tsmedizin Berlin","ror":"https://ror.org/001w7jn25","country_code":"DE","type":"healthcare","lineage":["https://openalex.org/I7877124"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M Maurer","raw_affiliation_strings":["Department of Dermatology, Charit\u00e9, Humboldt-Universit\u00e4t zu Berlin, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Dermatology, Charit\u00e9, Humboldt-Universit\u00e4t zu Berlin, Germany","institution_ids":["https://openalex.org/I39343248","https://openalex.org/I7877124"]}]},{"author_position":"middle","author":{"id":null,"display_name":"E Fischer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E Fischer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003429417","display_name":"Bori Handjiski","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Handjiski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062206937","display_name":"Esther von Stebut","orcid":"https://orcid.org/0000-0001-9802-9642","observed_orcids":["https://orcid.org/0000-0001-9802-9642"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E von Stebut","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5043613086","display_name":"Bernd Algermissen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Algermissen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073623300","display_name":"Assadollah Bavandi","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Bavandi","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5082322510","display_name":"Ralf Paus","orcid":"https://orcid.org/0000-0002-3492-9358","observed_orcids":["https://orcid.org/0000-0002-3492-9358"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Paus","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":3.82,"has_fulltext":false,"cited_by_count":102,"citation_normalized_percentile":{"value":0.92357495,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"77","issue":"4","first_page":"319","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11167","display_name":"Hair Growth and Disorders","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11167","display_name":"Hair Growth and Disorders","score":0.975600004196167,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.02319999970495701,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mast-cells","display_name":"mast cells","score":0.9629999995231628},{"id":"https://openalex.org/keywords/catagen","display_name":"catagen","score":0.8090000152587891},{"id":"https://openalex.org/keywords/hair-follicle-regression","display_name":"hair follicle regression","score":0.9860000014305115},{"id":"https://openalex.org/keywords/hair-cycle","display_name":"hair cycle","score":0.8650000095367432},{"id":"https://openalex.org/keywords/tissue-remodeling","display_name":"tissue remodeling","score":0.6589999794960022},{"id":"https://openalex.org/keywords/mast-cell-degranulation","display_name":"mast cell degranulation","score":0.9629999995231628},{"id":"https://openalex.org/keywords/substance-p","display_name":"substance P","score":0.9620000123977661},{"id":"https://openalex.org/keywords/acth","display_name":"ACTH","score":0.9990000128746033},{"id":"https://openalex.org/keywords/epithelial-cell-apoptosis","display_name":"epithelial apoptosis","score":0.6650000214576721},{"id":"https://openalex.org/keywords/dermal-mast-cells","display_name":"dermal mast cells","score":0.7440000176429749}],"concepts":[{"id":"https://openalex.org/C2777216303","wikidata":"https://www.wikidata.org/wiki/Q866324","display_name":"Hair follicle","level":2,"score":0.7842460870742798},{"id":"https://openalex.org/C2991961867","wikidata":"https://www.wikidata.org/wiki/Q866324","display_name":"Hair cycle","level":3,"score":0.7296130657196045},{"id":"https://openalex.org/C2781409172","wikidata":"https://www.wikidata.org/wiki/Q17056802","display_name":"Involution (esoterism)","level":3,"score":0.6876119375228882},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.5779611468315125},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.576045036315918},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.5725544691085815},{"id":"https://openalex.org/C49802076","wikidata":"https://www.wikidata.org/wiki/Q5251810","display_name":"Degranulation","level":3,"score":0.49858760833740234},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.3881436586380005},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15105947852134705},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.0990302562713623},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.07956761121749878},{"id":"https://openalex.org/C186720457","wikidata":"https://www.wikidata.org/wiki/Q7087","display_name":"Consciousness","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000324","descriptor_name":"Adrenocorticotropic Hormone","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004205","descriptor_name":"Cromolyn Sodium","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007150","descriptor_name":"Immunohistochemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D008407","descriptor_name":"Mast Cells","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008854","descriptor_name":"Microscopy, Electron","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011799","descriptor_name":"Quinazolines","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D012879","descriptor_name":"Skin Physiological Phenomena","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013373","descriptor_name":"Substance P","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018859","descriptor_name":"Hair Follicle","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018859","descriptor_name":"Hair Follicle","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D018859","descriptor_name":"Hair Follicle","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:9354767","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9354767","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Laboratory investigation; a journal of technical methods and pathology","raw_type":"Journal Article"},{"id":"mag:29430357","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/9354767","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.7246000170707703,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1995241596","https://openalex.org/W2615272271","https://openalex.org/W2342608831","https://openalex.org/W2061040342","https://openalex.org/W2937604584","https://openalex.org/W2156458099","https://openalex.org/W7096687282","https://openalex.org/W2007235090","https://openalex.org/W4366182218","https://openalex.org/W2062622837"],"abstract_inverted_index":{"Increasing":[0],"evidence":[1],"supports":[2],"a":[3,29,69,116],"role":[4,60,215],"for":[5,211],"mast":[6],"cells":[7],"(MC)":[8],"in":[9,39,64,127,148,163,175,196,224,229],"the":[10,16,23,41,53,58,93,103,128,135,176,184,197,213],"control":[11,198],"of":[12,22,61,75,99,106,119,130,153,179,199,216,221],"tissue":[13,222],"remodeling.":[14],"Using":[15],"cyclic":[17],"growth":[18,50],"and":[19,71,87,96,139,144,166,193],"regression":[20,67],"activity":[21],"murine":[24],"hair":[25,49,190],"follicle":[26],"(HF)":[27],"as":[28,189,218],"model,":[30],"we":[31,56,90],"have":[32],"previously":[33],"demonstrated":[34],"that":[35,186],"MC":[36,63,101,121,154,187,217],"are":[37,194],"involved":[38,195],"regulating":[40],"HF":[42,66,161,200],"transformation":[43,105],"from":[44],"resting":[45],"(telogen)":[46],"to":[47],"active":[48],"(anagen).":[51],"In":[52,133],"present":[54],"study,":[55],"investigated":[57],"potential":[59],"skin":[62,108],"spontaneous":[65],"(catagen),":[68],"rapid":[70],"highly":[72],"controlled":[73],"process":[74],"organ":[76,230],"involution":[77,231],"characterized":[78],"by":[79,124],"massive":[80],"epithelial":[81],"cell":[82],"apoptosis.":[83],"By":[84],"histochemistry,":[85],"immunohistochemistry,":[86],"electron":[88],"microscopy,":[89],"first":[91],"assessed":[92],"number,":[94],"location,":[95],"granulation":[97],"status":[98],"perifollicular":[100],"during":[102],"anagen-catagen-telogen":[104],"back":[107],"HF.":[109],"Spontaneous":[110],"catagen":[111,146,158,171],"induction":[112],"was":[113,173],"associated":[114],"with":[115],"dramatic":[117],"reduction":[118],"dermal":[120],"numbers,":[122],"preceded":[123],"an":[125,208],"increase":[126],"percentage":[129],"degranulated":[131],"MC.":[132,180],"vivo,":[134],"MC-secretagogues":[136],"substance":[137],"P":[138],"adrenocorticotropic":[140],"hormone":[141],"induced":[142],"premature":[143],"dystrophic":[145],"development":[147,172],"anagen":[149],"HF,":[150],"whereas":[151],"inhibitors":[152],"degranulation":[155],"retarded":[156,174],"normal":[157,168],"development.":[159],"Comparing":[160],"cycling":[162],"MC-deficient":[164],"WBB6F1-KitW/KitWv":[165],"congenic":[167],"(+/+)":[169],"mice,":[170],"virtual":[177],"absence":[178],"These":[181],"data":[182],"support":[183],"notion":[185],"function":[188],"cycle":[191],"regulators":[192],"regression.":[201],"The":[202],"mouse":[203],"model":[204],"employed":[205],"here":[206],"offers":[207],"excellent":[209],"tool":[210],"dissecting":[212],"physiologic":[214],"\"central":[219],"switchboards":[220],"remodeling\"":[223],"developmentally":[225],"regulated":[226],"systems,":[227],"specifically":[228],"processes.":[232]},"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}