{"id":"https://openalex.org/W2942848808","doi":null,"title":"Determination of cytotoxic, genotoxic and oxidative effects of Naringenin","display_name":"Determination of cytotoxic, genotoxic and oxidative effects of Naringenin","publication_year":2019,"publication_date":"2019-04-30","ids":{"openalex":"https://openalex.org/W2942848808","mag":"2942848808"},"language":"en","primary_location":{"id":"pmh:oai:ojs.www.actabiologicaturcica.info:article/276","doi":null,"is_oa":true,"landing_page_url":"https://www.actabiologicaturcica.com/index.php/abt/article/view/276","pdf_url":"https://www.actabiologicaturcica.com/index.php/abt/article/download/276/821","source":{"id":"https://openalex.org/S4306500272","display_name":"Acta biologica turcica","issn_l":"2458-7893","issn":["2458-7893"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2458-7893","raw_type":"info:eu-repo/semantics/article"},"volume":null,"type":"article","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.actabiologicaturcica.com/index.php/abt/article/download/276/821","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5077002190","display_name":"Sel\u00e7uk \u00c7eker","orcid":"https://orcid.org/0000-0002-2795-8863","observed_orcids":["https://orcid.org/0000-0002-2795-8863"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Sel\u00e7uk \u00c7eker","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-2795-8863","affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089692338","display_name":"Furkan Orhan","orcid":"https://orcid.org/0000-0001-6906-6604","observed_orcids":["https://orcid.org/0000-0001-6906-6604"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Furkan Orhan","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6906-6604","affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5032030878","display_name":"G\u00fcleray A\u011far","orcid":"https://orcid.org/0000-0002-8445-5082","observed_orcids":["https://orcid.org/0000-0002-8445-5082"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G\u00fcleray A\u011far","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-8445-5082","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0791,"has_fulltext":true,"cited_by_count":3,"citation_normalized_percentile":{"value":0.33741648,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"32","issue":"3","first_page":"117","last_page":"122"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.7813000082969666,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment","score":0.7813000082969666,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10035","display_name":"Phytochemicals and Antioxidant Activities","score":0.16410000622272491,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12582","display_name":"Flavonoids in Medical Research","score":0.04190000146627426,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/naringenin","display_name":"naringenin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/flavonoids","display_name":"flavonoids","score":0.9850000143051147},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9409999847412109},{"id":"https://openalex.org/keywords/genotoxicity","display_name":"genotoxicity","score":1.0},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.9660000205039978},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.9049999713897705},{"id":"https://openalex.org/keywords/pro-oxidant-effect","display_name":"pro-oxidant activity","score":0.7620000243186951},{"id":"https://openalex.org/keywords/endothelial-cells","display_name":"endothelial cells","score":0.8220000267028809},{"id":"https://openalex.org/keywords/lymphocytes","display_name":"lymphocytes","score":0.9240000247955322},{"id":"https://openalex.org/keywords/carbon-tetrachloride","display_name":"carbon tetrachloride","score":0.8450000286102295},{"id":"https://openalex.org/keywords/micronuclei","display_name":"micronuclei","score":0.718999981880188},{"id":"https://openalex.org/keywords/dna-damage","display_name":"DNA damage","score":0.5740000009536743},{"id":"https://openalex.org/keywords/phenolic-compounds","display_name":"phenolic compounds","score":0.6579999923706055}],"concepts":[{"id":"https://openalex.org/C2776848411","wikidata":"https://www.wikidata.org/wiki/Q418374","display_name":"Naringenin","level":4,"score":0.9608319401741028},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.807650089263916},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.6367229223251343},{"id":"https://openalex.org/C2776151105","wikidata":"https://www.wikidata.org/wiki/Q898814","display_name":"Oxidative stress","level":2,"score":0.6067690253257751},{"id":"https://openalex.org/C2778979269","wikidata":"https://www.wikidata.org/wiki/Q106951292","display_name":"Catalase","level":3,"score":0.572884738445282},{"id":"https://openalex.org/C2778959862","wikidata":"https://www.wikidata.org/wiki/Q1009245","display_name":"Genotoxicity","level":3,"score":0.5551839470863342},{"id":"https://openalex.org/C45080847","wikidata":"https://www.wikidata.org/wiki/Q1658004","display_name":"Micronucleus test","level":3,"score":0.5487565994262695},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.535161554813385},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.5121952891349792},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.4903995990753174},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.47094690799713135},{"id":"https://openalex.org/C2779054382","wikidata":"https://www.wikidata.org/wiki/Q72185287","display_name":"Flavonoid","level":3,"score":0.38229525089263916},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.19143128395080566},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13721534609794617},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.05242833495140076}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:ojs.www.actabiologicaturcica.info:article/276","doi":null,"is_oa":true,"landing_page_url":"https://www.actabiologicaturcica.com/index.php/abt/article/view/276","pdf_url":"https://www.actabiologicaturcica.com/index.php/abt/article/download/276/821","source":{"id":"https://openalex.org/S4306500272","display_name":"Acta biologica turcica","issn_l":"2458-7893","issn":["2458-7893"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2458-7893","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2942848808","doi":null,"is_oa":true,"landing_page_url":"http://www.actabiologicaturcica.com/index.php/abt/article/download/276/764","pdf_url":null,"source":{"id":"https://openalex.org/S4306500272","display_name":"Acta biologica turcica","issn_l":"2458-7893","issn":["2458-7893"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Acta biologica turcica","raw_type":null}],"best_oa_location":{"id":"pmh:oai:ojs.www.actabiologicaturcica.info:article/276","doi":null,"is_oa":true,"landing_page_url":"https://www.actabiologicaturcica.com/index.php/abt/article/view/276","pdf_url":"https://www.actabiologicaturcica.com/index.php/abt/article/download/276/821","source":{"id":"https://openalex.org/S4306500272","display_name":"Acta biologica turcica","issn_l":"2458-7893","issn":["2458-7893"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2458-7893","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2942848808.pdf","grobid_xml":"https://content.openalex.org/works/W2942848808.grobid-xml"},"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1966653494","https://openalex.org/W3136448219","https://openalex.org/W2512403946","https://openalex.org/W2937152975","https://openalex.org/W2730414675","https://openalex.org/W1794813415","https://openalex.org/W4285532441","https://openalex.org/W2037574696","https://openalex.org/W7132396720","https://openalex.org/W4296625576"],"abstract_inverted_index":{"The":[0,174],"phenolic":[1,40],"compounds":[2,21,41,59],"obtained":[3],"from":[4],"plants":[5,45],"are":[6],"responsible":[7],"for":[8,28,185],"the":[9,12,15,29,39,52,66,75,88,121,132,141,215],"protection":[10],"of":[11,18,24,31,57,65,74,78,96,109,143,180],"organism":[13],"against":[14,135],"harmful":[16],"effects":[17,95,150,184],"reactive":[19],"oxygen":[20],"by":[22],"means":[23],"antioxidant":[25,48,183],"activities":[26,56,77],"and":[27,49,55,93,125,147,158,163,171,182,207],"treatment":[30],"disorders":[32],"related":[33],"to":[34,86],"radical":[35],"damage.":[36],"However,":[37],"since":[38],"frequently":[42],"found":[43,100],"in":[44,89,101,104,129,178,214],"may":[46],"have":[47],"prooxidant":[50],"effects,":[51],"chemical":[53],"properties":[54,134,165],"these":[58],"must":[60],"be":[61,195,212],"known.":[62],"Naringenin":[63,110,186,198],"is":[64,84,99],"most":[67,175],"researched":[68],"flavonoid":[69],"members,":[70],"it":[71,83],"possesses":[72],"majority":[73],"biological":[76],"flavonoids.":[79],"In":[80],"this":[81],"work,":[82],"aimed":[85],"investigate":[87],"vitro":[90],"cytotoxic,":[91],"genotoxic":[92,149,164],"oxidative":[94,133],"Naringenin,":[97],"which":[98],"many":[102],"foods":[103],"our":[105],"diet.The":[106],"cytotoxic":[107,162],"effect":[108],"on":[111],"human":[112,130],"umbilical":[113],"cord":[114],"vein":[115],"endothelial":[116],"cells":[117],"were":[118,138,151],"analysed":[119],"with":[120,140,153],"lactate":[122],"dehydrogenase":[123],"release":[124],"cell":[126,155],"proliferation":[127],"methods;":[128],"lymphocytes":[131],"carbon":[136],"tetrachloride":[137],"examined":[139],"measurement":[142],"catalase,":[144],"superoxide":[145],"dismutase":[146],"malondialdehyde;":[148],"investigated":[152],"single":[154],"gel":[156],"electrophoresis":[157],"micronuclei":[159],"methods.Naringenin":[160],"revealed":[161],"especially":[166],"at":[167],"high":[168,204],"concentrations":[169],"(100":[170],"200":[172],"\u03bcM).":[173],"effective":[176],"results":[177],"terms":[179],"antigenotoxic":[181],"was":[187],"observed":[188],"8":[189],"\u03bcM":[190],"concentration.":[191],"Therefore,":[192],"care":[193],"should":[194,211],"taken":[196],"that":[197],"does":[199],"not":[200],"consume":[201],"food":[202],"containing":[203],"levels":[205],"unconsciously,":[206],"individual":[208],"concentration":[209],"adjustments":[210],"made":[213],"treatments":[216],"applied.":[217]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2019-05-09T00:00:00"}