{"id":"https://openalex.org/W2941968892","doi":"https://doi.org/10.1038/s41598-019-43057-1","title":"Adoptive transfer of Trichinella spiralis-activated macrophages can ameliorate both Th1- and Th2-activated inflammation in murine models","display_name":"Adoptive transfer of Trichinella spiralis-activated macrophages can ameliorate both Th1- and Th2-activated inflammation in murine models","publication_year":2019,"publication_date":"2019-04-25","ids":{"openalex":"https://openalex.org/W2941968892","doi":"https://doi.org/10.1038/s41598-019-43057-1","mag":"2941968892","pmid":"https://pubmed.ncbi.nlm.nih.gov/31024043","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6484028"},"language":"en","primary_location":{"id":"doi:10.1038/s41598-019-43057-1","doi":"https://doi.org/10.1038/s41598-019-43057-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-43057-1","pdf_url":"https://www.nature.com/articles/s41598-019-43057-1.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.nature.com/articles/s41598-019-43057-1.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5048448756","display_name":"Shin Ae Kang","orcid":"https://orcid.org/0000-0001-9934-9787","observed_orcids":["https://orcid.org/0000-0001-9934-9787"]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Shin Ae Kang","raw_affiliation_strings":["Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0001-9934-9787","affiliations":[{"raw_affiliation_string":"Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103584641","display_name":"Mi-Kyung Park","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Mi-Kyung Park","raw_affiliation_strings":["Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000614964","display_name":"Sang Kyun Park","orcid":"https://orcid.org/0000-0002-0195-3175","observed_orcids":["https://orcid.org/0000-0002-0195-3175"]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Sang Kyun Park","raw_affiliation_strings":["Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100714681","display_name":"Jun Ho Choi","orcid":"https://orcid.org/0000-0002-7416-3377","observed_orcids":["https://orcid.org/0000-0002-7416-3377","https://orcid.org/0009-0004-8583-6129","https://orcid.org/0009-0006-4331-2401"]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Jun Ho Choi","raw_affiliation_strings":["Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea"],"raw_orcid":"https://orcid.org/0000-0002-7416-3377","affiliations":[{"raw_affiliation_string":"Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Da In Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"Da In Lee","raw_affiliation_strings":["Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016789692","display_name":"So Myong Song","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":false,"raw_author_name":"So Myong Song","raw_affiliation_strings":["Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea","institution_ids":["https://openalex.org/I4921948"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5044335175","display_name":"Hak Sun Yu","orcid":"https://orcid.org/0000-0002-6696-7981","observed_orcids":["https://orcid.org/0000-0002-6696-7981"]},"institutions":[{"id":"https://openalex.org/I4921948","display_name":"Pusan National University","ror":"https://ror.org/01an57a31","country_code":"KR","type":"education","lineage":["https://openalex.org/I4921948"]}],"countries":["KR"],"is_corresponding":true,"raw_author_name":"Hak Sun Yu","raw_affiliation_strings":["Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea. hsyu@pusan.ac.kr","Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea. hsyu@pusan.ac.kr","institution_ids":["https://openalex.org/I4921948"]},{"raw_affiliation_string":"Department of Parasitology and Tropical Medicine, School of Medicine, Pusan National University, Yangsan, Gyeongsangnam-do, Republic of Korea","institution_ids":["https://openalex.org/I4921948"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5044335175"],"corresponding_institution_ids":["https://openalex.org/I4921948"],"apc_list":{"value":1790,"currency":"USD","value_usd":1790},"apc_paid":{"value":1790,"currency":"USD","value_usd":1790},"fwci":6.8501,"has_fulltext":true,"cited_by_count":50,"citation_normalized_percentile":{"value":0.98154657,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"9","issue":"1","first_page":"6547","last_page":"6547"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":0.9506999850273132,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10695","display_name":"Parasites and Host Interactions","score":0.9506999850273132,"subfield":{"id":"https://openalex.org/subfields/2405","display_name":"Parasitology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.015699999406933784,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11702","display_name":"Parasitic Diseases Research and Treatment","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/trichinella-spiralis","display_name":"Trichinella spiralis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/m2-macrophages","display_name":"M2 macrophages","score":0.8539999723434448},{"id":"https://openalex.org/keywords/macrophage-polarization","display_name":"macrophage polarization","score":0.8550000190734863},{"id":"https://openalex.org/keywords/adoptive-transfer","display_name":"adoptive transfer","score":0.6959999799728394},{"id":"https://openalex.org/keywords/helminth-immunomodulation","display_name":"helminth immunomodulation","score":0.871999979019165},{"id":"https://openalex.org/keywords/excretory-secretory-proteins","display_name":"excretory-secretory proteins","score":0.8799999952316284},{"id":"https://openalex.org/keywords/th1-inflammation","display_name":"Th1 inflammation","score":0.6710000038146973},{"id":"https://openalex.org/keywords/type-2-inflammation","display_name":"type 2 inflammation","score":0.9869999885559082},{"id":"https://openalex.org/keywords/allergic-airway-inflammation","display_name":"allergic airway inflammation","score":0.8429999947547913},{"id":"https://openalex.org/keywords/colitis","display_name":"colitis","score":0.7009999752044678},{"id":"https://openalex.org/keywords/dss-induced-colitis","display_name":"DSS-induced colitis","score":0.8519999980926514},{"id":"https://openalex.org/keywords/airway-hyperresponsiveness","display_name":"airway hyperresponsiveness","score":0.847000002861023},{"id":"https://openalex.org/keywords/eosinophil-infiltration","display_name":"eosinophil infiltration","score":0.8730000257492065},{"id":"https://openalex.org/keywords/goblet-cell-hyperplasia","display_name":"goblet cell hyperplasia","score":0.921999990940094},{"id":"https://openalex.org/keywords/cd206","display_name":"CD206","score":0.871999979019165},{"id":"https://openalex.org/keywords/arg1","display_name":"Arg1","score":0.7580000162124634}],"concepts":[{"id":"https://openalex.org/C2781320125","wikidata":"https://www.wikidata.org/wiki/Q730937","display_name":"Trichinella spiralis","level":3,"score":0.9195142984390259},{"id":"https://openalex.org/C90375314","wikidata":"https://www.wikidata.org/wiki/Q3537484","display_name":"Adoptive cell transfer","level":4,"score":0.7847944498062134},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.6676114797592163},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4792756736278534},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3309592604637146},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.32245513796806335},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.2787732481956482},{"id":"https://openalex.org/C165901193","wikidata":"https://www.wikidata.org/wiki/Q3129936","display_name":"Helminths","level":2,"score":0.2107502818107605},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.1377112865447998}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003713","descriptor_name":"Dendritic Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004195","descriptor_name":"Disease Models, Animal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007249","descriptor_name":"Inflammation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016212","descriptor_name":"Transforming Growth Factor beta","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016753","descriptor_name":"Interleukin-10","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017160","descriptor_name":"Trichinella spiralis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D018417","descriptor_name":"Th1 Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018418","descriptor_name":"Th2 Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051858","descriptor_name":"Forkhead Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1038/s41598-019-43057-1","doi":"https://doi.org/10.1038/s41598-019-43057-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-43057-1","pdf_url":"https://www.nature.com/articles/s41598-019-43057-1.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5489395","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6484028","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:31024043","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31024043","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific reports","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6484028","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6484028/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Sci Rep","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:8df77d172487482dbcbf62ce1f7ed007","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/8df77d172487482dbcbf62ce1f7ed007","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Scientific Reports, Vol 9, Iss 1, Pp 1-17 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1038/s41598-019-43057-1","doi":"https://doi.org/10.1038/s41598-019-43057-1","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41598-019-43057-1","pdf_url":"https://www.nature.com/articles/s41598-019-43057-1.pdf","source":{"id":"https://openalex.org/S196734849","display_name":"Scientific Reports","issn_l":"2045-2322","issn":["2045-2322"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-class-a","anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319908","host_organization_name":"Nature Portfolio","host_organization_lineage":["https://openalex.org/P4310319908","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Nature Portfolio","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Scientific Reports","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320320671","display_name":"National Research Foundation","ror":"https://ror.org/05s0g1g46"},{"id":"https://openalex.org/F4320322120","display_name":"National Research Foundation of Korea","ror":"https://ror.org/013aysd81"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2941968892.pdf","grobid_xml":"https://content.openalex.org/works/W2941968892.grobid-xml"},"referenced_works_count":99,"referenced_works":["https://openalex.org/W1498639064","https://openalex.org/W1518095394","https://openalex.org/W1554862259","https://openalex.org/W1561018825","https://openalex.org/W1586801024","https://openalex.org/W1604044665","https://openalex.org/W1787590335","https://openalex.org/W1895793844","https://openalex.org/W1905007654","https://openalex.org/W1963651122","https://openalex.org/W1965256830","https://openalex.org/W1967369695","https://openalex.org/W1970838369","https://openalex.org/W1977083682","https://openalex.org/W1977179270","https://openalex.org/W1978990512","https://openalex.org/W1981056356","https://openalex.org/W1983168290","https://openalex.org/W1987052976","https://openalex.org/W1994158191","https://openalex.org/W1995158194","https://openalex.org/W1999315698","https://openalex.org/W1999816171","https://openalex.org/W2002967638","https://openalex.org/W2005361432","https://openalex.org/W2008382341","https://openalex.org/W2012579360","https://openalex.org/W2013565627","https://openalex.org/W2018440551","https://openalex.org/W2018521741","https://openalex.org/W2018996778","https://openalex.org/W2019221616","https://openalex.org/W2027388269","https://openalex.org/W2034000325","https://openalex.org/W2036260707","https://openalex.org/W2048007675","https://openalex.org/W2050040343","https://openalex.org/W2054080213","https://openalex.org/W2055739616","https://openalex.org/W2061123122","https://openalex.org/W2065210647","https://openalex.org/W2065821720","https://openalex.org/W2070855360","https://openalex.org/W2075306666","https://openalex.org/W2077124851","https://openalex.org/W2081810806","https://openalex.org/W2091783404","https://openalex.org/W2092235636","https://openalex.org/W2093705034","https://openalex.org/W2094659815","https://openalex.org/W2099473703","https://openalex.org/W2104909111","https://openalex.org/W2105772739","https://openalex.org/W2105908328","https://openalex.org/W2108323291","https://openalex.org/W2109593516","https://openalex.org/W2113702305","https://openalex.org/W2115907216","https://openalex.org/W2116424088","https://openalex.org/W2121827176","https://openalex.org/W2122591224","https://openalex.org/W2123303185","https://openalex.org/W2123793821","https://openalex.org/W2130529018","https://openalex.org/W2133536768","https://openalex.org/W2136722399","https://openalex.org/W2138930949","https://openalex.org/W2140380746","https://openalex.org/W2140472119","https://openalex.org/W2140737233","https://openalex.org/W2152958432","https://openalex.org/W2154233644","https://openalex.org/W2163175900","https://openalex.org/W2164613235","https://openalex.org/W2176102850","https://openalex.org/W2189019287","https://openalex.org/W2192928441","https://openalex.org/W2206617731","https://openalex.org/W2209250550","https://openalex.org/W2301044272","https://openalex.org/W2342275754","https://openalex.org/W2420226158","https://openalex.org/W2485004164","https://openalex.org/W2534854440","https://openalex.org/W2582576746","https://openalex.org/W2602325668","https://openalex.org/W2605104303","https://openalex.org/W2616838417","https://openalex.org/W2737816390","https://openalex.org/W2764291671","https://openalex.org/W2782691834","https://openalex.org/W2790105026","https://openalex.org/W2790156596","https://openalex.org/W2792517138","https://openalex.org/W2793701608","https://openalex.org/W2795402810","https://openalex.org/W2810580234","https://openalex.org/W2887840888","https://openalex.org/W2905827542"],"related_works":["https://openalex.org/W4389073936","https://openalex.org/W3118636971","https://openalex.org/W2163716475","https://openalex.org/W4220795410","https://openalex.org/W3090744476","https://openalex.org/W2094188996","https://openalex.org/W2895781417","https://openalex.org/W2091783404","https://openalex.org/W2809961294","https://openalex.org/W2954715025"],"abstract_inverted_index":{"cells,":[0],"a":[1,10,93,295],"target":[2],"for":[3,283,297],"immunomodulation":[4],"by":[5,26,83,133,190],"the":[6,17,39,47,85,115,135,151,192,237],"helminth":[7,260,275],"parasite,":[8],"play":[9],"critical":[11],"role":[12],"in":[13,236,247,289],"initiating":[14],"and":[15,51,72,90,104,126,144,157,172,178,206,221,232,251,259,274,285,291],"modulating":[16],"host":[18,30],"immune":[19,31],"response":[20,32],"to":[21],"parasite.":[22],"The":[23,182],"precise":[24],"mechanism":[25],"which":[27,224],"helminths":[28],"modulate":[29],"is":[33,279,292],"not":[34],"fully":[35],"understood.":[36],"To":[37],"determine":[38],"functions":[40],"of":[41,49,61,87,117,137,175,184,194,196,208,268],"parasite-induced":[42],"M2":[43,52,80,264],"macrophages,":[44],"we":[45,96],"compared":[46],"effects":[48],"M1":[50],"macrophages":[53,67,98,109,162,269,278],"obtained":[54,99,270],"from":[55,100,271],"Trichinella":[56],"spiralis-infected":[57,102,155,249],"mice":[58,103,111,156,250,273,290],"with":[59,150],"those":[60],"T.":[62,76,101,105,154,158,248,252],"spiralis":[63,77,106,159,253],"excretory/secretory":[64],"(ES)":[65],"protein-treated":[66,108,161,255],"on":[68],"experimental":[69],"intestinal":[70],"inflammation":[71,187,215],"allergic":[73,185,213,242],"airway":[74,186,198,214,287],"inflammation.":[75],"infection":[78,258],"induced":[79,217],"macrophage":[81],"polarization":[82],"increasing":[84],"expression":[86],"CD206,":[88],"ARG1,":[89],"Fizz2.":[91],"In":[92],"single":[94],"application,":[95],"introduced":[97],"ES":[107,160,254,261,276],"into":[110],"tail":[112],"veins":[113],"before":[114],"induction":[116],"dextran":[118],"sulfate":[119],"sodium":[120],"(DSS)-induced":[121],"colitis,":[122],"ovalbumin":[123],"(OVA)-alum":[124],"sensitization,":[125],"OVA":[127,222],"challenge.":[128],"Colitis":[129],"severity":[130,136,183,193],"was":[131,188,216],"assessed":[132,189],"determining":[134,191],"colitis":[138],"symptoms,":[139],"colon":[140],"length,":[141],"histopathologic":[142,204],"parameters,":[143,205],"Th1-related":[145],"inflammatory":[146,210,299],"cytokine":[147,180,228],"levels.":[148],"Compared":[149],"DSS-colitis":[152],"group,":[153],"showed":[163],"significantly":[164,225,245],"lower":[165],"disease":[166],"activity":[167],"index":[168],"(DAI)":[169],"at":[170],"sacrifice":[171],"smaller":[173],"reductions":[174],"body":[176],"weight":[177],"proinflammatory":[179],"level.":[181],"symptoms":[195,243],"inflammation,":[197],"hyperresponsiveness":[199],"(AHR),":[200],"differential":[201],"cell":[202,234],"counts,":[203],"levels":[207],"Th2-related":[209,227],"cytokines.":[211],"Severe":[212],"after":[218],"OVA-alum":[219],"sensitization":[220],"challenge,":[223],"increased":[226],"levels,":[229],"eosinophil":[230],"infiltration,":[231],"goblet":[233],"hyperplasia":[235],"lung.":[238],"However,":[239],"these":[240],"severe":[241],"were":[244],"decreased":[246],"macrophages.":[256,265],"Helminth":[257],"proteins":[262],"induce":[263],"Adoptive":[266],"transfer":[267],"helminth-infected":[272],"protein-activated":[277],"an":[280],"effective":[281],"treatment":[282],"preventing":[284],"treating":[286,298],"allergy":[288],"promising":[293],"as":[294],"therapeutic":[296],"diseases.":[300]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-05-03T00:00:00"}