{"id":"https://openalex.org/W2941444779","doi":"https://doi.org/10.1101/621920","title":"Super resolution imaging of a distinct chromatin loop in human lymphoblastoid cells","display_name":"Super resolution imaging of a distinct chromatin loop in human lymphoblastoid cells","publication_year":2019,"publication_date":"2019-04-29","ids":{"openalex":"https://openalex.org/W2941444779","doi":"https://doi.org/10.1101/621920","mag":"2941444779"},"language":"en","primary_location":{"id":"doi:10.1101/621920","doi":"https://doi.org/10.1101/621920","is_oa":true,"landing_page_url":"https://doi.org/10.1101/621920","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2019/04/29/621920.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"volume":null,"type":"preprint","indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.biorxiv.org/content/biorxiv/early/2019/04/29/621920.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5089657589","display_name":"Jacqueline Jufen Zhu","orcid":"https://orcid.org/0000-0001-6416-4563","observed_orcids":["https://orcid.org/0000-0001-6416-4563"]},"institutions":[{"id":"https://openalex.org/I4405260184","display_name":"The Jackson Laboratory for Genomic Medicine","ror":"https://ror.org/03cew3973","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256","https://openalex.org/I4405260184"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jacqueline Jufen Zhu","raw_affiliation_strings":["Department of Genetics and Genome Sciences, University of Connecticut Health Center, 400 Farmington Avenue, Farmington, CT 06030, USA;","The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Genetics and Genome Sciences, University of Connecticut Health Center, 400 Farmington Avenue, Farmington, CT 06030, USA;","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USA;","institution_ids":["https://openalex.org/I4405260184"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059710464","display_name":"Zofia Parteka-Tojek","orcid":"https://orcid.org/0000-0002-6573-2988","observed_orcids":["https://orcid.org/0000-0002-6573-2988"]},"institutions":[{"id":"https://openalex.org/I108403487","display_name":"Warsaw University of Technology","ror":"https://ror.org/00y0xnp53","country_code":"PL","type":"education","lineage":["https://openalex.org/I108403487"]},{"id":"https://openalex.org/I4654613","display_name":"University of Warsaw","ror":"https://ror.org/039bjqg32","country_code":"PL","type":"education","lineage":["https://openalex.org/I4654613"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Zofia Parteka","raw_affiliation_strings":["Centre of New Technologies, University of Warsaw, S. Banacha 2c, 02-097 Warsaw, Poland;","Faculty of Mathematics and Information Science, Warsaw University of Technology, Warsaw, Poland;"],"raw_orcid":"https://orcid.org/0000-0002-6573-2988","affiliations":[{"raw_affiliation_string":"Centre of New Technologies, University of Warsaw, S. Banacha 2c, 02-097 Warsaw, Poland;","institution_ids":["https://openalex.org/I4654613"]},{"raw_affiliation_string":"Faculty of Mathematics and Information Science, Warsaw University of Technology, Warsaw, Poland;","institution_ids":["https://openalex.org/I108403487"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030211608","display_name":"Byoungkoo Lee","orcid":"https://orcid.org/0000-0002-0067-9944","observed_orcids":["https://orcid.org/0000-0002-0067-9944"]},"institutions":[{"id":"https://openalex.org/I4405260184","display_name":"The Jackson Laboratory for Genomic Medicine","ror":"https://ror.org/03cew3973","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256","https://openalex.org/I4405260184"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Byoungkoo Lee","raw_affiliation_strings":["The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USA;"],"raw_orcid":"https://orcid.org/0000-0002-0067-9944","affiliations":[{"raw_affiliation_string":"The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USA;","institution_ids":["https://openalex.org/I4405260184"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037907861","display_name":"Przemys\u0142aw Sza\u0142aj","orcid":"https://orcid.org/0000-0003-3569-3735","observed_orcids":["https://orcid.org/0000-0003-3569-3735"]},"institutions":[{"id":"https://openalex.org/I146122375","display_name":"Medical University of Bia\u0142ystok","ror":"https://ror.org/00y4ya841","country_code":"PL","type":"education","lineage":["https://openalex.org/I146122375"]},{"id":"https://openalex.org/I4654613","display_name":"University of Warsaw","ror":"https://ror.org/039bjqg32","country_code":"PL","type":"education","lineage":["https://openalex.org/I4654613"]},{"id":"https://openalex.org/I878454856","display_name":"Hasselt University","ror":"https://ror.org/04nbhqj75","country_code":"BE","type":"education","lineage":["https://openalex.org/I878454856"]}],"countries":["BE","PL"],"is_corresponding":false,"raw_author_name":"Przemyslaw Szalaj","raw_affiliation_strings":["Center for Bioinformatics and Data Analysis, Medical University of Bialystok, Jana Kilinskiego 1, 15-089 Bialystok, Poland;","Centre of New Technologies, University of Warsaw, S. Banacha 2c, 02-097 Warsaw, Poland;","I-BioStat, Hasselt University, Agoralaan D, 3590 Diepenbeek, Belgium;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Center for Bioinformatics and Data Analysis, Medical University of Bialystok, Jana Kilinskiego 1, 15-089 Bialystok, Poland;","institution_ids":["https://openalex.org/I146122375"]},{"raw_affiliation_string":"Centre of New Technologies, University of Warsaw, S. Banacha 2c, 02-097 Warsaw, Poland;","institution_ids":["https://openalex.org/I4654613"]},{"raw_affiliation_string":"I-BioStat, Hasselt University, Agoralaan D, 3590 Diepenbeek, Belgium;","institution_ids":["https://openalex.org/I878454856"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058008586","display_name":"Ping Wang","orcid":"https://orcid.org/0000-0001-8992-1233","observed_orcids":["https://orcid.org/0000-0001-8992-1233"]},"institutions":[{"id":"https://openalex.org/I4405260184","display_name":"The Jackson Laboratory for Genomic Medicine","ror":"https://ror.org/03cew3973","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256","https://openalex.org/I4405260184"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ping Wang","raw_affiliation_strings":["The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USA;","institution_ids":["https://openalex.org/I4405260184"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036429418","display_name":"Karolina Jodkowska","orcid":"https://orcid.org/0000-0002-6103-5915","observed_orcids":["https://orcid.org/0000-0002-6103-5915"]},"institutions":[{"id":"https://openalex.org/I4654613","display_name":"University of Warsaw","ror":"https://ror.org/039bjqg32","country_code":"PL","type":"education","lineage":["https://openalex.org/I4654613"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Karolina Jodkowska","raw_affiliation_strings":["Centre of New Technologies, University of Warsaw, S. Banacha 2c, 02-097 Warsaw, Poland;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Centre of New Technologies, University of Warsaw, S. Banacha 2c, 02-097 Warsaw, Poland;","institution_ids":["https://openalex.org/I4654613"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022244521","display_name":"Jesse Aaron","orcid":"https://orcid.org/0000-0002-7543-9590","observed_orcids":["https://orcid.org/0000-0002-7543-9590"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I195573530","display_name":"Janelia Research Campus","ror":"https://ror.org/013sk6x84","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jesse Aaron","raw_affiliation_strings":["Advanced Imaging Center, Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Imaging Center, Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA;","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047668731","display_name":"Teng\u2010Leong Chew","orcid":"https://orcid.org/0000-0002-3139-7560","observed_orcids":["https://orcid.org/0000-0002-3139-7560"]},"institutions":[{"id":"https://openalex.org/I1344073410","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410"]},{"id":"https://openalex.org/I195573530","display_name":"Janelia Research Campus","ror":"https://ror.org/013sk6x84","country_code":"US","type":"facility","lineage":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Teng-Leong Chew","raw_affiliation_strings":["Advanced Imaging Center, Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA;"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Advanced Imaging Center, Janelia Research Campus, Howard Hughes Medical Institute, 19700 Helix Drive, Ashburn, VA 20147, USA;","institution_ids":["https://openalex.org/I1344073410","https://openalex.org/I195573530"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021916927","display_name":"Dariusz Plewczy\u0144ski","orcid":"https://orcid.org/0000-0002-3840-7610","observed_orcids":["https://orcid.org/0000-0002-3840-7610"]},"institutions":[{"id":"https://openalex.org/I108403487","display_name":"Warsaw University of Technology","ror":"https://ror.org/00y0xnp53","country_code":"PL","type":"education","lineage":["https://openalex.org/I108403487"]},{"id":"https://openalex.org/I4654613","display_name":"University of Warsaw","ror":"https://ror.org/039bjqg32","country_code":"PL","type":"education","lineage":["https://openalex.org/I4654613"]}],"countries":["PL"],"is_corresponding":false,"raw_author_name":"Dariusz Plewczynski","raw_affiliation_strings":["Centre of New Technologies, University of Warsaw, S. Banacha 2c, 02-097 Warsaw, Poland;","Faculty of Mathematics and Information Science, Warsaw University of Technology, Warsaw, Poland;"],"raw_orcid":"https://orcid.org/0000-0002-3840-7610","affiliations":[{"raw_affiliation_string":"Centre of New Technologies, University of Warsaw, S. Banacha 2c, 02-097 Warsaw, Poland;","institution_ids":["https://openalex.org/I4654613"]},{"raw_affiliation_string":"Faculty of Mathematics and Information Science, Warsaw University of Technology, Warsaw, Poland;","institution_ids":["https://openalex.org/I108403487"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028790437","display_name":"Yijun Ruan","orcid":"https://orcid.org/0000-0001-5881-569X","observed_orcids":["https://orcid.org/0000-0001-5881-569X"]},"institutions":[{"id":"https://openalex.org/I204823248","display_name":"Huazhong Agricultural University","ror":"https://ror.org/023b72294","country_code":"CN","type":"education","lineage":["https://openalex.org/I204823248"]},{"id":"https://openalex.org/I4405260184","display_name":"The Jackson Laboratory for Genomic Medicine","ror":"https://ror.org/03cew3973","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210115256","https://openalex.org/I4405260184"]},{"id":"https://openalex.org/I75929689","display_name":"UConn Health","ror":"https://ror.org/02kzs4y22","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I75929689"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Yijun Ruan","raw_affiliation_strings":["Department of Genetics and Genome Sciences, University of Connecticut Health Center, 400 Farmington Avenue, Farmington, CT 06030, USA;","National key laboratory of crop genetic improvement, College of Life Sciences and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China","The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USA;"],"raw_orcid":"https://orcid.org/0000-0001-5881-569X","affiliations":[{"raw_affiliation_string":"Department of Genetics and Genome Sciences, University of Connecticut Health Center, 400 Farmington Avenue, Farmington, CT 06030, USA;","institution_ids":["https://openalex.org/I75929689"]},{"raw_affiliation_string":"National key laboratory of crop genetic improvement, College of Life Sciences and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China","institution_ids":["https://openalex.org/I204823248"]},{"raw_affiliation_string":"The Jackson Laboratory for Genomic Medicine, 10 Discovery Drive, Farmington, CT 06030, USA;","institution_ids":["https://openalex.org/I4405260184"]}]}],"institutions":[],"countries_distinct_count":4,"institutions_distinct_count":9,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":1,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.8701000213623047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.8701000213623047,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10540","display_name":"Advanced Fluorescence Microscopy Techniques","score":0.09030000120401382,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10923","display_name":"Force Microscopy Techniques and Applications","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/3107","display_name":"Atomic and Molecular Physics, and Optics"},"field":{"id":"https://openalex.org/fields/31","display_name":"Physics and Astronomy"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chromatin-looping","display_name":"chromatin looping","score":0.9150000214576721},{"id":"https://openalex.org/keywords/3d-genome-organization","display_name":"3D genome organization","score":0.859000027179718},{"id":"https://openalex.org/keywords/super-resolution-imaging","display_name":"super-resolution imaging","score":0.7279999852180481},{"id":"https://openalex.org/keywords/single-molecule-imaging","display_name":"single-molecule imaging","score":0.6790000200271606},{"id":"https://openalex.org/keywords/long-range-chromatin-interactions","display_name":"long-range chromatin interactions","score":0.8190000057220459},{"id":"https://openalex.org/keywords/gm12878-cells","display_name":"GM12878 cells","score":0.8790000081062317},{"id":"https://openalex.org/keywords/hi-c-data","display_name":"Hi-C data","score":0.47600001096725464},{"id":"https://openalex.org/keywords/chromatin-folding","display_name":"chromatin folding","score":0.6869999766349792},{"id":"https://openalex.org/keywords/higher-order-chromatin-structure","display_name":"higher-order chromatin structure","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.934424102306366},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.635691225528717},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.5276134014129639},{"id":"https://openalex.org/C67258246","wikidata":"https://www.wikidata.org/wiki/Q5065897","display_name":"ChIA-PET","level":5,"score":0.4993109703063965},{"id":"https://openalex.org/C189206191","wikidata":"https://www.wikidata.org/wiki/Q222046","display_name":"Genomics","level":4,"score":0.48748159408569336},{"id":"https://openalex.org/C2776545253","wikidata":"https://www.wikidata.org/wiki/Q5464292","display_name":"Folding (DSP implementation)","level":2,"score":0.4571024179458618},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.44873011112213135},{"id":"https://openalex.org/C93946551","wikidata":"https://www.wikidata.org/wiki/Q5113914","display_name":"Chromosome conformation capture","level":5,"score":0.4134725332260132},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.29942139983177185},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.29917240142822266},{"id":"https://openalex.org/C84772758","wikidata":"https://www.wikidata.org/wiki/Q271794","display_name":"Nucleosome","level":4,"score":0.29057830572128296},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.1696760356426239},{"id":"https://openalex.org/C119599485","wikidata":"https://www.wikidata.org/wiki/Q43035","display_name":"Electrical engineering","level":1,"score":0.0},{"id":"https://openalex.org/C111936080","wikidata":"https://www.wikidata.org/wiki/Q913367","display_name":"Enhancer","level":4,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1101/621920","doi":"https://doi.org/10.1101/621920","is_oa":true,"landing_page_url":"https://doi.org/10.1101/621920","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2019/04/29/621920.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"}],"best_oa_location":{"id":"doi:10.1101/621920","doi":"https://doi.org/10.1101/621920","is_oa":true,"landing_page_url":"https://doi.org/10.1101/621920","pdf_url":"https://www.biorxiv.org/content/biorxiv/early/2019/04/29/621920.full.pdf","source":{"id":"https://openalex.org/S4306402567","display_name":"bioRxiv (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"bioRxiv","raw_type":"posted-content"},"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G6604330024","display_name":"Nucleome Positioning System for Spatiotemporal Genome Organization and Regulation","funder_award_id":"U54DK107967","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G8036758133","display_name":null,"funder_award_id":"CA16212","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"},{"id":"https://openalex.org/G825450032","display_name":null,"funder_award_id":"1U54DK107967-01","funder_id":"https://openalex.org/F4320321042","funder_display_name":"Fundacja na rzecz Nauki Polskiej"},{"id":"https://openalex.org/G849249608","display_name":null,"funder_award_id":"CA18127","funder_id":"https://openalex.org/F4320320300","funder_display_name":"European Commission"}],"funders":[{"id":"https://openalex.org/F4320306082","display_name":"Howard Hughes Medical Institute","ror":"https://ror.org/006w34k90"},{"id":"https://openalex.org/F4320306202","display_name":"Gordon and Betty Moore Foundation","ror":"https://ror.org/006wxqw41"},{"id":"https://openalex.org/F4320320300","display_name":"European Commission","ror":"https://ror.org/00k4n6c32"},{"id":"https://openalex.org/F4320321042","display_name":"Fundacja na rzecz Nauki Polskiej","ror":"https://ror.org/048zd9m77"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2941444779.pdf","grobid_xml":"https://content.openalex.org/works/W2941444779.grobid-xml"},"referenced_works_count":40,"referenced_works":["https://openalex.org/W1859117663","https://openalex.org/W1968894421","https://openalex.org/W1969691479","https://openalex.org/W1973062929","https://openalex.org/W1981235416","https://openalex.org/W1983159345","https://openalex.org/W1985621639","https://openalex.org/W1991815226","https://openalex.org/W2003266654","https://openalex.org/W2006311225","https://openalex.org/W2013571070","https://openalex.org/W2018626566","https://openalex.org/W2021462917","https://openalex.org/W2045951304","https://openalex.org/W2048485003","https://openalex.org/W2054669424","https://openalex.org/W2064537118","https://openalex.org/W2069638502","https://openalex.org/W2070021921","https://openalex.org/W2075802914","https://openalex.org/W2076202384","https://openalex.org/W2080479776","https://openalex.org/W2087571144","https://openalex.org/W2090037139","https://openalex.org/W2098984423","https://openalex.org/W2101234009","https://openalex.org/W2104496262","https://openalex.org/W2133161896","https://openalex.org/W2144792857","https://openalex.org/W2147403429","https://openalex.org/W2195190137","https://openalex.org/W2267070684","https://openalex.org/W2279402243","https://openalex.org/W2402173511","https://openalex.org/W2407512034","https://openalex.org/W2491201136","https://openalex.org/W2540292904","https://openalex.org/W2739969873","https://openalex.org/W2804231115","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W4281255130","https://openalex.org/W3133449953","https://openalex.org/W4296312299","https://openalex.org/W2952052372","https://openalex.org/W3161304531","https://openalex.org/W3003652588","https://openalex.org/W2955232984","https://openalex.org/W4402269061","https://openalex.org/W4365445746","https://openalex.org/W4387830742"],"abstract_inverted_index":{"Abstract":[0],"The":[1,119],"three-dimensional":[2],"genome":[3,33],"structure":[4,53],"plays":[5],"a":[6,63,122],"fundamental":[7],"role":[8],"in":[9,17,67],"gene":[10],"regulation":[11],"and":[12,105,129],"cellular":[13],"functions.":[14],"Recent":[15],"studies":[16],"genomics":[18],"based":[19],"on":[20],"sequencing":[21,130],"technologies":[22],"inferred":[23],"the":[24,32,38,51,77,82,88,92,108,117,126,133,140],"very":[25,141],"basic":[26],"functional":[27],"chromatin":[28,36,40,55,65,79,89,137],"folding":[29],"structures":[30,90,138],"of":[31,54,76,135],"known":[34],"as":[35,98],"loops,":[37],"long-range":[39],"interactions":[41],"that":[42],"are":[43],"often":[44],"mediated":[45],"by":[46,110,148],"protein":[47],"factors.":[48],"To":[49,86],"visualize":[50],"looping":[52,99],"we":[56,71,95],"applied":[57],"super-resolution":[58],"microscopy":[59],"iPALM":[60],"to":[61,115],"image":[62],"specific":[64],"loop":[66],"GM12878":[68],"cells.":[69],"Totally,":[70],"have":[72],"generated":[73],"six":[74],"images":[75],"target":[78],"region":[80],"at":[81],"single":[83],"molecule":[84],"resolution.":[85],"infer":[87],"from":[91],"captured":[93],"images,":[94],"modeled":[96],"them":[97],"conformations":[100],"using":[101],"different":[102],"computational":[103],"algorithms":[104],"then":[106],"evaluated":[107],"models":[109],"comparing":[111],"with":[112],"Hi-C":[113],"data":[114,128],"examine":[116],"concordance.":[118],"results":[120],"showed":[121],"good":[123],"correlation":[124],"between":[125],"imaging":[127],"data,":[131],"suggesting":[132],"visualization":[134],"higher-order":[136],"for":[139],"short":[142],"genomic":[143],"segments":[144],"can":[145],"be":[146],"realized":[147],"microscopic":[149],"imaging.":[150]},"counts_by_year":[{"year":2021,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2019-05-03T00:00:00"}