{"id":"https://openalex.org/W2941421140","doi":"https://doi.org/10.1063/1.5086671","title":"Microfluidics on the fly: Inexpensive rapid fabrication of thermally laminated microfluidic devices for live imaging and multimodal perturbations of multicellular systems","display_name":"Microfluidics on the fly: Inexpensive rapid fabrication of thermally laminated microfluidic devices for live imaging and multimodal perturbations of multicellular systems","publication_year":2019,"publication_date":"2019-03-01","ids":{"openalex":"https://openalex.org/W2941421140","doi":"https://doi.org/10.1063/1.5086671","mag":"2941421140","pmid":"https://pubmed.ncbi.nlm.nih.gov/31065310","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6486393"},"language":"en","primary_location":{"id":"doi:10.1063/1.5086671","doi":"https://doi.org/10.1063/1.5086671","is_oa":true,"landing_page_url":"https://doi.org/10.1063/1.5086671","pdf_url":"https://pubs.aip.org/aip/bmf/article-pdf/doi/10.1063/1.5086671/14596595/024111_1_online.pdf","source":{"id":"https://openalex.org/S173107507","display_name":"Biomicrofluidics","issn_l":"1932-1058","issn":["1932-1058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://pubs.aip.org/aip/bmf/article-pdf/doi/10.1063/1.5086671/14596595/024111_1_online.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085721373","display_name":"Megan Levis","orcid":"https://orcid.org/0000-0002-3328-2732","observed_orcids":["https://orcid.org/0000-0002-3328-2732"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan Levis","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032898218","display_name":"Nilay Kumar","orcid":"https://orcid.org/0009-0007-7164-1656","observed_orcids":["https://orcid.org/0009-0007-7164-1656"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nilay Kumar","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072303709","display_name":"Emily Apakian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily Apakian","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Cesar Moreno","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cesar Moreno","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Ulises Hernandez","orcid":"https://orcid.org/0000-0003-4114-2243","observed_orcids":["https://orcid.org/0000-0003-4114-2243"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ulises Hernandez","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA"],"raw_orcid":"https://orcid.org/0000-0003-4114-2243","affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103832994","display_name":"Ana Olivares","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ana Olivares","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022325334","display_name":"Fernando Ontiveros","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I910567637","display_name":"St. John Fisher University","ror":"https://ror.org/05ech9204","country_code":"US","type":"education","lineage":["https://openalex.org/I910567637"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Fernando Ontiveros","raw_affiliation_strings":["Biology Department, St. John Fisher College 2 , Rochester, New York 14618, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Department, St. John Fisher College 2 , Rochester, New York 14618, USA","institution_ids":["https://openalex.org/I910567637"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5089489482","display_name":"Jeremiah J. Zartman","orcid":"https://orcid.org/0000-0001-7195-7203","observed_orcids":["https://orcid.org/0000-0001-7195-7203"]},"institutions":[{"id":"https://openalex.org/I107639228","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43","country_code":"US","type":"education","lineage":["https://openalex.org/I107639228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeremiah J. Zartman","raw_affiliation_strings":["Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA"],"raw_orcid":"https://orcid.org/0000-0001-7195-7203","affiliations":[{"raw_affiliation_string":"Department of Chemical and Biomolecular Engineering, University of Notre Dame 1 , Notre Dame, Indiana 46556, USA","institution_ids":["https://openalex.org/I107639228"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.9679,"has_fulltext":true,"cited_by_count":23,"citation_normalized_percentile":{"value":0.70239562,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"13","issue":"2","first_page":"024111","last_page":"024111"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10412","display_name":"Microfluidic and Capillary Electrophoresis Applications","score":0.961899995803833,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.031300000846385956,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/microfluidic-device-fabrication","display_name":"microfluidic fabrication","score":0.8119999766349792},{"id":"https://openalex.org/keywords/low-cost-microfluidic-devices","display_name":"low-cost microfluidics","score":0.8180000185966492},{"id":"https://openalex.org/keywords/developmental-biology","display_name":"developmental biology","score":0.6669999957084656},{"id":"https://openalex.org/keywords/drosophila-wing-imaginal-disc","display_name":"Drosophila wing imaginal disc","score":0.9639999866485596},{"id":"https://openalex.org/keywords/mechanical-loading","display_name":"mechanical loading","score":0.6439999938011169},{"id":"https://openalex.org/keywords/mechanobiology","display_name":"mechanobiology","score":0.8339999914169312},{"id":"https://openalex.org/keywords/live-cell-imaging","display_name":"live-cell imaging","score":0.6919999718666077},{"id":"https://openalex.org/keywords/multicellular-systems","display_name":"multicellular systems","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C8673954","wikidata":"https://www.wikidata.org/wiki/Q138845","display_name":"Microfluidics","level":2,"score":0.9370225667953491},{"id":"https://openalex.org/C74318829","wikidata":"https://www.wikidata.org/wiki/Q36458","display_name":"Multicellular organism","level":3,"score":0.6674129366874695},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.6396980285644531},{"id":"https://openalex.org/C118524077","wikidata":"https://www.wikidata.org/wiki/Q7554001","display_name":"Soft lithography","level":4,"score":0.5319764018058777},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.5047417879104614},{"id":"https://openalex.org/C165062768","wikidata":"https://www.wikidata.org/wiki/Q1145644","display_name":"Biomimetics","level":2,"score":0.48880836367607117},{"id":"https://openalex.org/C136525101","wikidata":"https://www.wikidata.org/wiki/Q5428139","display_name":"Fabrication","level":3,"score":0.4673113524913788},{"id":"https://openalex.org/C2780171871","wikidata":"https://www.wikidata.org/wiki/Q6804676","display_name":"Mechanobiology","level":2,"score":0.44807225465774536},{"id":"https://openalex.org/C15526883","wikidata":"https://www.wikidata.org/wiki/Q6657126","display_name":"Live cell imaging","level":3,"score":0.44276660680770874},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.17096275091171265},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.15673571825027466},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.12835410237312317},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1063/1.5086671","doi":"https://doi.org/10.1063/1.5086671","is_oa":true,"landing_page_url":"https://doi.org/10.1063/1.5086671","pdf_url":"https://pubs.aip.org/aip/bmf/article-pdf/doi/10.1063/1.5086671/14596595/024111_1_online.pdf","source":{"id":"https://openalex.org/S173107507","display_name":"Biomicrofluidics","issn_l":"1932-1058","issn":["1932-1058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6486393","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6486393","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"Text"},{"id":"pmid:31065310","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31065310","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"Journal Article"},{"id":"pmh:oai:fisherpub.sjf.edu:biology_facpub-1052","doi":null,"is_oa":false,"landing_page_url":"https://fisherpub.sjf.edu/biology_facpub/51","pdf_url":null,"source":{"id":"https://openalex.org/S4306401245","display_name":"Fisher Digital Publications (St. John Fisher College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I910567637","host_organization_name":"St. John Fisher University","host_organization_lineage":["https://openalex.org/I910567637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biology Faculty/Staff Publications","raw_type":"text"},{"id":"pmh:oai:fisherpub.sjfc.edu:biology_facpub-1052","doi":null,"is_oa":false,"landing_page_url":"https://fisherpub.sjfc.edu/biology_facpub/51","pdf_url":null,"source":{"id":"https://openalex.org/S4306401245","display_name":"Fisher Digital Publications (St. John Fisher College)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I910567637","host_organization_name":"St. John Fisher University","host_organization_lineage":["https://openalex.org/I910567637"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biology Faculty/Staff Publications","raw_type":"text"}],"best_oa_location":{"id":"doi:10.1063/1.5086671","doi":"https://doi.org/10.1063/1.5086671","is_oa":true,"landing_page_url":"https://doi.org/10.1063/1.5086671","pdf_url":"https://pubs.aip.org/aip/bmf/article-pdf/doi/10.1063/1.5086671/14596595/024111_1_online.pdf","source":{"id":"https://openalex.org/S173107507","display_name":"Biomicrofluidics","issn_l":"1932-1058","issn":["1932-1058"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320257","host_organization_name":"American Institute of Physics","host_organization_lineage":["https://openalex.org/P4310320257"],"host_organization_lineage_names":["American Institute of Physics"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biomicrofluidics","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G107421238","display_name":"CAREER:Integrative Analysis for Reverse Engineering Embryonic Pattern Repair Mechanisms","funder_award_id":"1553826","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"},{"id":"https://openalex.org/G229238088","display_name":"Regulation and function of multicellular calcium signaling in epithelial growth and regeneration","funder_award_id":"R35GM124935","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320310260","display_name":"University of Notre Dame","ror":"https://ror.org/00mkhxb43"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320333901","display_name":"Notre Dame Integrated Imaging Facility, University of Notre Dame","ror":null},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337390","display_name":"Division of Chemical, Bioengineering, Environmental, and Transport Systems","ror":"https://ror.org/0471zv972"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2941421140.pdf","grobid_xml":"https://content.openalex.org/works/W2941421140.grobid-xml"},"referenced_works_count":71,"referenced_works":["https://openalex.org/W187600693","https://openalex.org/W1150019108","https://openalex.org/W1512126150","https://openalex.org/W1936732090","https://openalex.org/W1965558704","https://openalex.org/W1969435013","https://openalex.org/W1987817703","https://openalex.org/W1997937948","https://openalex.org/W2000671199","https://openalex.org/W2001607419","https://openalex.org/W2001704578","https://openalex.org/W2002403131","https://openalex.org/W2010567868","https://openalex.org/W2010617931","https://openalex.org/W2010889353","https://openalex.org/W2013520568","https://openalex.org/W2031110489","https://openalex.org/W2031524718","https://openalex.org/W2034763647","https://openalex.org/W2035179295","https://openalex.org/W2054464790","https://openalex.org/W2062182733","https://openalex.org/W2068842224","https://openalex.org/W2071234893","https://openalex.org/W2074862008","https://openalex.org/W2076922024","https://openalex.org/W2077210071","https://openalex.org/W2105976126","https://openalex.org/W2111235285","https://openalex.org/W2119305994","https://openalex.org/W2119889685","https://openalex.org/W2120255779","https://openalex.org/W2141027011","https://openalex.org/W2142801207","https://openalex.org/W2161007406","https://openalex.org/W2167279371","https://openalex.org/W2282761819","https://openalex.org/W2290729006","https://openalex.org/W2397146032","https://openalex.org/W2429501371","https://openalex.org/W2470933532","https://openalex.org/W2490777982","https://openalex.org/W2504352321","https://openalex.org/W2531877534","https://openalex.org/W2536845639","https://openalex.org/W2540898869","https://openalex.org/W2559221547","https://openalex.org/W2600587427","https://openalex.org/W2605007731","https://openalex.org/W2734881282","https://openalex.org/W2737864209","https://openalex.org/W2766215723","https://openalex.org/W2769036386","https://openalex.org/W2770668003","https://openalex.org/W2772934865","https://openalex.org/W2779094772","https://openalex.org/W2782564370","https://openalex.org/W2786679662","https://openalex.org/W2789963013","https://openalex.org/W2810398043","https://openalex.org/W2885629375","https://openalex.org/W2888749732","https://openalex.org/W2901483548","https://openalex.org/W2908861263","https://openalex.org/W2914715938","https://openalex.org/W2915000726","https://openalex.org/W2945873193","https://openalex.org/W2980047616","https://openalex.org/W4206811718","https://openalex.org/W4211057669","https://openalex.org/W4233599022"],"related_works":["https://openalex.org/W2989869699","https://openalex.org/W4400656457","https://openalex.org/W4380836698","https://openalex.org/W2748501168","https://openalex.org/W3026804676","https://openalex.org/W3205774126","https://openalex.org/W1529713568","https://openalex.org/W2118310215","https://openalex.org/W147221702","https://openalex.org/W2592482250"],"abstract_inverted_index":{"Microfluidic":[0],"devices":[1,24,77,88,209],"provide":[2,218],"a":[3,102,138,145],"platform":[4],"for":[5,21,34,81,181,197,210],"analyzing":[6],"both":[7,115],"natural":[8],"and":[9,17,52,68,83,95,108,118,123,212,217],"synthetic":[10],"multicellular":[11],"systems.":[12],"Currently,":[13],"substantial":[14],"capital":[15],"investment":[16],"expertise":[18],"are":[19,79,112],"required":[20],"creating":[22],"microfluidic":[23,76,140],"using":[25],"standard":[26],"soft-lithography.":[27],"These":[28,87],"requirements":[29],"present":[30],"barriers":[31],"to":[32,161],"entry":[33],"many":[35],"nontraditional":[36],"users":[37],"of":[38,59,121,130,153,165,176,190,206,224],"microfluidics,":[39],"including":[40],"developmental":[41,62,171],"biology":[42],"laboratories.":[43],"Therefore,":[44],"fabrication":[45],"methodologies":[46],"that":[47,78,111,148,187],"enable":[48],"rapid":[49],"device":[50,147],"iteration":[51],"work":[53],"\u201cout-of-the-box\u201d":[54],"can":[55],"accelerate":[56],"the":[57,96,134,163,177,182,188,191,204,222],"integration":[58],"microfluidics":[60],"with":[61,91,114,137],"biology.":[63],"Here,":[64],"we":[65,106,126,143],"have":[66],"created":[67,144],"characterized":[69],"low-cost":[70],"hybrid":[71,207],"polyethylene":[72],"terephthalate":[73],"laminate":[74],"(PETL)":[75],"suitable":[80],"cell":[82,93],"micro-organ":[84],"culture":[85],"assays.":[86],"were":[89],"validated":[90],"mammalian":[92],"lines":[94],"Drosophila":[97],"wing":[98,135,167,179],"imaginal":[99],"disc":[100],"as":[101],"model":[103],"micro-organ.":[104],"First,":[105],"developed":[107],"tested":[109],"PETLs":[110],"compatible":[113],"long-term":[116],"cultures":[117],"high-resolution":[119],"imaging":[120],"cells":[122],"organs.":[124],"Further,":[125],"achieved":[127],"spatiotemporal":[128],"control":[129],"chemical":[131],"gradients":[132],"across":[133],"discs":[136,168,180],"multilayered":[139,146],"device.":[141],"Finally,":[142],"enables":[149],"controllable":[150],"mechanical":[151,156,184],"loading":[152,185],"micro-organs.":[154],"This":[155],"actuation":[157],"assay":[158],"was":[159],"used":[160],"characterize":[162],"response":[164],"larval":[166],"at":[169],"different":[170],"stages.":[172],"Interestingly,":[173],"increased":[174,194],"deformation":[175],"older":[178],"same":[183],"suggests":[186],"compliance":[189],"organ":[192,225],"is":[193],"in":[195],"preparation":[196],"subsequent":[198],"morphogenesis.":[199],"Together,":[200],"these":[201],"results":[202],"demonstrate":[203],"applicability":[205],"PETL":[208],"biochemical":[211],"mechanobiology":[213],"studies":[214],"on":[215],"micro-organs":[216],"new":[219],"insights":[220],"into":[221],"mechanics":[223],"development.":[226]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":3}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2019-05-03T00:00:00"}