{"id":"https://openalex.org/W2941237136","doi":"https://doi.org/10.1002/chem.201901537","title":"Ditocopheryl Sulfides and Disulfides: Synthesis and Antioxidant Profile","display_name":"Ditocopheryl Sulfides and Disulfides: Synthesis and Antioxidant Profile","publication_year":2019,"publication_date":"2019-04-24","ids":{"openalex":"https://openalex.org/W2941237136","doi":"https://doi.org/10.1002/chem.201901537","mag":"2941237136","pmid":"https://pubmed.ncbi.nlm.nih.gov/31017702"},"language":"en","primary_location":{"id":"doi:10.1002/chem.201901537","doi":"https://doi.org/10.1002/chem.201901537","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chem.201901537","pdf_url":null,"source":{"id":"https://openalex.org/S68911691","display_name":"Chemistry - A European Journal","issn_l":"0947-6539","issn":["0947-6539","1521-3765"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry \u2013 A European Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5043683189","display_name":"Caterina Viglianisi","orcid":"https://orcid.org/0000-0002-2451-5856","observed_orcids":["https://orcid.org/0000-0002-2451-5856"]},"institutions":[{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Caterina Viglianisi","raw_affiliation_strings":["Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy"],"raw_orcid":"https://orcid.org/0000-0002-2451-5856","affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy","institution_ids":["https://openalex.org/I45084792"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064970692","display_name":"Kristian Vasa","orcid":"https://orcid.org/0000-0001-7014-5115","observed_orcids":["https://orcid.org/0000-0001-7014-5115"]},"institutions":[{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Kristian Vasa","raw_affiliation_strings":["Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy","institution_ids":["https://openalex.org/I45084792"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016424809","display_name":"Damiano Tanini","orcid":"https://orcid.org/0000-0001-8930-3566","observed_orcids":["https://orcid.org/0000-0001-8930-3566"]},"institutions":[{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Damiano Tanini","raw_affiliation_strings":["Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy"],"raw_orcid":"https://orcid.org/0000-0001-8930-3566","affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy","institution_ids":["https://openalex.org/I45084792"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010751411","display_name":"Antonella Capperucci","orcid":"https://orcid.org/0000-0003-1087-8143","observed_orcids":["https://orcid.org/0000-0003-1087-8143"]},"institutions":[{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Antonella Capperucci","raw_affiliation_strings":["Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy","institution_ids":["https://openalex.org/I45084792"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010305154","display_name":"Riccardo Amorati","orcid":"https://orcid.org/0000-0002-6417-9957","observed_orcids":["https://orcid.org/0000-0002-6417-9957"]},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Riccardo Amorati","raw_affiliation_strings":["Department of Chemistry \"G. Ciamician\", University of Bologna, Via S. Giacomo 11, 40126 Bologna, Italy"],"raw_orcid":"https://orcid.org/0000-0002-6417-9957","affiliations":[{"raw_affiliation_string":"Department of Chemistry \"G. Ciamician\", University of Bologna, Via S. Giacomo 11, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025623237","display_name":"Luca Valgimigli","orcid":"https://orcid.org/0000-0003-2229-1075","observed_orcids":["https://orcid.org/0000-0003-2229-1075"]},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Luca Valgimigli","raw_affiliation_strings":["Department of Chemistry \"G. Ciamician\", University of Bologna, Via S. Giacomo 11, 40126 Bologna, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry \"G. Ciamician\", University of Bologna, Via S. Giacomo 11, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051973824","display_name":"Andrea Baschieri","orcid":"https://orcid.org/0000-0002-2108-8190","observed_orcids":["https://orcid.org/0000-0002-2108-8190"]},"institutions":[{"id":"https://openalex.org/I9360294","display_name":"University of Bologna","ror":"https://ror.org/01111rn36","country_code":"IT","type":"education","lineage":["https://openalex.org/I9360294"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Andrea Baschieri","raw_affiliation_strings":["Department of Chemistry \"G. Ciamician\", University of Bologna, Via S. Giacomo 11, 40126 Bologna, Italy"],"raw_orcid":"https://orcid.org/0000-0002-2108-8190","affiliations":[{"raw_affiliation_string":"Department of Chemistry \"G. Ciamician\", University of Bologna, Via S. Giacomo 11, 40126 Bologna, Italy","institution_ids":["https://openalex.org/I9360294"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5034288302","display_name":"Stefano Menichetti","orcid":"https://orcid.org/0000-0001-6745-7484","observed_orcids":["https://orcid.org/0000-0001-6745-7484"]},"institutions":[{"id":"https://openalex.org/I45084792","display_name":"University of Florence","ror":"https://ror.org/04jr1s763","country_code":"IT","type":"education","lineage":["https://openalex.org/I45084792"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Stefano Menichetti","raw_affiliation_strings":["Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy"],"raw_orcid":"https://orcid.org/0000-0001-6745-7484","affiliations":[{"raw_affiliation_string":"Department of Chemistry \u201cUgo Schiff\u201d University of Florence  Via Della Lastruccia 3\u201313, Sesto Fiorentino Firenze Italy","institution_ids":["https://openalex.org/I45084792"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5034288302"],"corresponding_institution_ids":["https://openalex.org/I45084792"],"apc_list":{"value":4000,"currency":"USD","value_usd":4000},"apc_paid":null,"fwci":1.3506,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.77298334,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"25","issue":"38","first_page":"9108","last_page":"9116"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.5917999744415283,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10445","display_name":"Antioxidant Activity and Oxidative Stress","score":0.5917999744415283,"subfield":{"id":"https://openalex.org/subfields/2704","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13013","display_name":"Free Radicals and Antioxidants","score":0.3391000032424927,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12189","display_name":"Sulfur-Based Synthesis Techniques","score":0.01769999973475933,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tocopherol-derivatives","display_name":"tocopherol derivatives","score":0.6949999928474426},{"id":"https://openalex.org/keywords/regioselective-synthesis","display_name":"regioselective synthesis","score":0.8410000205039978},{"id":"https://openalex.org/keywords/antioxidant-activity","display_name":"antioxidant activity","score":0.875},{"id":"https://openalex.org/keywords/hydrogen-bonding","display_name":"hydrogen bonding","score":0.7960000038146973}],"concepts":[{"id":"https://openalex.org/C59759590","wikidata":"https://www.wikidata.org/wiki/Q2275927","display_name":"Regioselectivity","level":3,"score":0.807536244392395},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.6462825536727905},{"id":"https://openalex.org/C518881349","wikidata":"https://www.wikidata.org/wiki/Q682","display_name":"Sulfur","level":2,"score":0.6379328370094299},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.635006308555603},{"id":"https://openalex.org/C2780378348","wikidata":"https://www.wikidata.org/wiki/Q25351438","display_name":"Ring (chemistry)","level":2,"score":0.6177743673324585},{"id":"https://openalex.org/C2781076698","wikidata":"https://www.wikidata.org/wiki/Q718074","display_name":"Aryl","level":3,"score":0.48153525590896606},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.33487382531166077},{"id":"https://openalex.org/C161790260","wikidata":"https://www.wikidata.org/wiki/Q82264","display_name":"Catalysis","level":2,"score":0.048890620470047},{"id":"https://openalex.org/C2780263894","wikidata":"https://www.wikidata.org/wiki/Q335268","display_name":"Alkyl","level":2,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1002/chem.201901537","doi":"https://doi.org/10.1002/chem.201901537","is_oa":false,"landing_page_url":"https://doi.org/10.1002/chem.201901537","pdf_url":null,"source":{"id":"https://openalex.org/S68911691","display_name":"Chemistry - A European Journal","issn_l":"0947-6539","issn":["0947-6539","1521-3765"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry \u2013 A European Journal","raw_type":"journal-article"},{"id":"pmid:31017702","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31017702","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Chemistry (Weinheim an der Bergstrasse, Germany)","raw_type":"Journal Article"},{"id":"pmh:oai:cris.unibo.it:11585/694781","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11585/694781","pdf_url":null,"source":{"id":"https://openalex.org/S4306402579","display_name":"Archivio istituzionale della ricerca (Alma Mater Studiorum Universit\u00e0 di Bologna)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210117483","host_organization_name":"Istituto di Ematologia di Bologna","host_organization_lineage":["https://openalex.org/I4210117483"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:flore.unifi.it:2158/1172396","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2158/1172396","pdf_url":null,"source":{"id":"https://openalex.org/S4306402033","display_name":"Florence Research (University of Florence)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45084792","host_organization_name":"University of Florence","host_organization_lineage":["https://openalex.org/I45084792"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:ricerca.univaq.it:11697/139268","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11697/139268","pdf_url":null,"source":{"id":"https://openalex.org/S7407055225","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 degli Studi dell Aquila","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G400351501","display_name":null,"funder_award_id":"RFO2017","funder_id":"https://openalex.org/F4320323553","funder_display_name":"Universit\u00e0 di Bologna"}],"funders":[{"id":"https://openalex.org/F4320321685","display_name":"Ente Cassa di Risparmio di Firenze","ror":"https://ror.org/03wrep505"},{"id":"https://openalex.org/F4320323553","display_name":"Universit\u00e0 di Bologna","ror":"https://ror.org/01111rn36"},{"id":"https://openalex.org/F4320329094","display_name":"Fondazione Cassa di Risparmio di Firenze","ror":"https://ror.org/049wkn258"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":67,"referenced_works":["https://openalex.org/W1877388778","https://openalex.org/W1965193351","https://openalex.org/W1977107321","https://openalex.org/W1981055213","https://openalex.org/W1986302424","https://openalex.org/W1993419555","https://openalex.org/W1996141629","https://openalex.org/W2004720309","https://openalex.org/W2009907465","https://openalex.org/W2020841266","https://openalex.org/W2039446143","https://openalex.org/W2045583078","https://openalex.org/W2046017419","https://openalex.org/W2046114376","https://openalex.org/W2050772862","https://openalex.org/W2061942802","https://openalex.org/W2063164870","https://openalex.org/W2063941091","https://openalex.org/W2066077163","https://openalex.org/W2067074603","https://openalex.org/W2067373914","https://openalex.org/W2082492554","https://openalex.org/W2087866473","https://openalex.org/W2091004055","https://openalex.org/W2092157292","https://openalex.org/W2094355815","https://openalex.org/W2097066562","https://openalex.org/W2104742343","https://openalex.org/W2108633369","https://openalex.org/W2133235682","https://openalex.org/W2134862613","https://openalex.org/W2136873289","https://openalex.org/W2139602777","https://openalex.org/W2141517019","https://openalex.org/W2142133558","https://openalex.org/W2148010836","https://openalex.org/W2149281625","https://openalex.org/W2275945593","https://openalex.org/W2290952296","https://openalex.org/W2320299850","https://openalex.org/W2324034002","https://openalex.org/W2330928954","https://openalex.org/W2520253973","https://openalex.org/W2530638008","https://openalex.org/W2539297832","https://openalex.org/W2549677166","https://openalex.org/W2589396809","https://openalex.org/W2728927614","https://openalex.org/W2743722804","https://openalex.org/W2769735589","https://openalex.org/W2772449614","https://openalex.org/W2792976855","https://openalex.org/W2810873425","https://openalex.org/W2892455413","https://openalex.org/W2893717624","https://openalex.org/W2894911692","https://openalex.org/W2910232874","https://openalex.org/W2949518441","https://openalex.org/W2950627517","https://openalex.org/W2950920872","https://openalex.org/W2951664985","https://openalex.org/W2951672271","https://openalex.org/W2951947378","https://openalex.org/W2952678765","https://openalex.org/W2953021350","https://openalex.org/W4230932208","https://openalex.org/W4244337461"],"related_works":["https://openalex.org/W2157057435","https://openalex.org/W2949204348","https://openalex.org/W2038594439","https://openalex.org/W2009177134","https://openalex.org/W4390100183","https://openalex.org/W4239022780","https://openalex.org/W4413637798","https://openalex.org/W1604418035","https://openalex.org/W4365814351","https://openalex.org/W2061197337"],"abstract_inverted_index":{"Abstract":[0],"Symmetrical":[1],"ditocopheryl":[2,9],"disulfides":[3],"(Toc)2S2":[4],"and":[5,7,29,42],"symmetrical":[6],"unsymmetrical":[8],"sulfides":[10],"(Toc)2S":[11],"were":[12,56],"simply":[13],"prepared":[14],"under":[15],"remarkably":[16],"mild":[17],"conditions":[18],"with":[19],"complete":[20],"control":[21],"of":[22,38,51],"the":[23,48],"regiochemistry":[24],"by":[25,58],"using":[26],"\u03b4\u2010,":[27],"\u03b3\u2010,":[28],"\u03b2\u2010tocopheryl\u2010N\u2010thiophthalimides":[30],"(Toc\u2010NSPht)":[31],"as":[32],"common":[33],"starting":[34],"materials.":[35],"The":[36],"roles":[37],"sulfur":[39],"atom(s),":[40],"H\u2010bond":[41],"aryl":[43],"ring":[44],"substitution":[45],"pattern":[46],"on":[47],"antioxidant":[49],"profile":[50],"these":[52],"new":[53],"compounds,":[54],"which":[55],"assembled":[57],"linking":[59],"together":[60],"two":[61],"tocopheryl":[62],"units,":[63],"are":[64],"also":[65],"discussed.":[66]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2019-05-03T00:00:00"}