{"id":"https://openalex.org/W2941223368","doi":"https://doi.org/10.1093/ckj/sfz034","title":"Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis","display_name":"Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis","publication_year":2019,"publication_date":"2019-03-21","ids":{"openalex":"https://openalex.org/W2941223368","doi":"https://doi.org/10.1093/ckj/sfz034","mag":"2941223368","pmid":"https://pubmed.ncbi.nlm.nih.gov/32082556","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/7025329"},"language":"en","primary_location":{"id":"doi:10.1093/ckj/sfz034","doi":"https://doi.org/10.1093/ckj/sfz034","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ckj/sfz034","pdf_url":"https://academic.oup.com/ckj/article-pdf/13/1/75/32500099/sfz034.pdf","source":{"id":"https://openalex.org/S117236744","display_name":"Clinical Kidney Journal","issn_l":"2048-8505","issn":["2048-8505","2048-8513"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Kidney Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://academic.oup.com/ckj/article-pdf/13/1/75/32500099/sfz034.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5008906136","display_name":"Myles Selig Wolf","orcid":"https://orcid.org/0000-0002-1127-1442","observed_orcids":["https://orcid.org/0000-0002-1127-1442"]},"institutions":[{"id":"https://openalex.org/I170897317","display_name":"Duke University","ror":"https://ror.org/00py81415","country_code":"US","type":"education","lineage":["https://openalex.org/I170897317"]},{"id":"https://openalex.org/I4210126298","display_name":"Duke Medical Center","ror":"https://ror.org/03njmea73","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210126298","https://openalex.org/I4210144876"]},{"id":"https://openalex.org/I4405286153","display_name":"Duke Clinical Research Institute","ror":"https://ror.org/019mv4g96","country_code":"US","type":"facility","lineage":["https://openalex.org/I170897317","https://openalex.org/I4405286153"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Myles Wolf","raw_affiliation_strings":["Department of Medicine, Division of Nephrology, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Nephrology, Duke Clinical Research Institute, Duke University School of Medicine, Durham, NC, USA","institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4405286153"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072020289","display_name":"Geoffrey A. Block","orcid":"https://orcid.org/0000-0002-4646-7074","observed_orcids":["https://orcid.org/0000-0002-4646-7074"]},"institutions":[{"id":"https://openalex.org/I4210148132","display_name":"Colorado Kidney Care","ror":"https://ror.org/05556yk85","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210148132"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Geoffrey A Block","raw_affiliation_strings":["Denver Nephrology, Research Divsion, Denver, CO, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Denver Nephrology, Research Divsion, Denver, CO, USA","institution_ids":["https://openalex.org/I4210148132"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034939991","display_name":"Glenn Matthew Chertow","orcid":"https://orcid.org/0000-0002-7599-0534","observed_orcids":["https://orcid.org/0000-0002-7599-0534"]},"institutions":[{"id":"https://openalex.org/I4210137306","display_name":"Stanford Medicine","ror":"https://ror.org/03mtd9a03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]},{"id":"https://openalex.org/I97018004","display_name":"Stanford University","ror":"https://ror.org/00f54p054","country_code":"US","type":"education","lineage":["https://openalex.org/I97018004"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Glenn M Chertow","raw_affiliation_strings":["Department of Medicine, Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Nephrology, Stanford University School of Medicine, Palo Alto, CA, USA","institution_ids":["https://openalex.org/I4210137306","https://openalex.org/I97018004"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020691655","display_name":"Kerry Cooper","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320553840","display_name":"Amgen (United States)","ror":"https://ror.org/03g03ge92","country_code":"US","type":"company","lineage":["https://openalex.org/I1320553840"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kerry Cooper","raw_affiliation_strings":["Amgen, Inc., Thousand Oaks, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amgen, Inc., Thousand Oaks, CA, USA","institution_ids":["https://openalex.org/I1320553840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061460476","display_name":"Bruno L. Fouqueray","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320553840","display_name":"Amgen (United States)","ror":"https://ror.org/03g03ge92","country_code":"US","type":"company","lineage":["https://openalex.org/I1320553840"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Bruno Fouqueray","raw_affiliation_strings":["Amgen, Inc., Thousand Oaks, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amgen, Inc., Thousand Oaks, CA, USA","institution_ids":["https://openalex.org/I1320553840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074659892","display_name":"Sharon M. Moe","orcid":"https://orcid.org/0000-0003-3562-9725","observed_orcids":["https://orcid.org/0000-0003-3562-9725"]},"institutions":[{"id":"https://openalex.org/I4388446366","display_name":"Indiana University Indianapolis","ror":"https://ror.org/03eftgw80","country_code":"US","type":"education","lineage":["https://openalex.org/I4388446366","https://openalex.org/I592451"]},{"id":"https://openalex.org/I4394709130","display_name":"Indiana University School of Medicine","ror":"https://ror.org/02ets8c94","country_code":"US","type":"education","lineage":["https://openalex.org/I4394709130","https://openalex.org/I592451"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sharon M Moe","raw_affiliation_strings":["Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Division of Nephrology, Indiana University School of Medicine, Indianapolis, IN, USA","institution_ids":["https://openalex.org/I4388446366","https://openalex.org/I4394709130"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083147929","display_name":"Yan Ping Sun","orcid":"https://orcid.org/0000-0001-8525-7814","observed_orcids":["https://orcid.org/0000-0001-8525-7814"]},"institutions":[{"id":"https://openalex.org/I1320553840","display_name":"Amgen (United States)","ror":"https://ror.org/03g03ge92","country_code":"US","type":"company","lineage":["https://openalex.org/I1320553840"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yan Sun","raw_affiliation_strings":["Amgen, Inc., Thousand Oaks, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amgen, Inc., Thousand Oaks, CA, USA","institution_ids":["https://openalex.org/I1320553840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000847677","display_name":"Holly Tomlin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1320553840","display_name":"Amgen (United States)","ror":"https://ror.org/03g03ge92","country_code":"US","type":"company","lineage":["https://openalex.org/I1320553840"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Holly Tomlin","raw_affiliation_strings":["Amgen, Inc., Thousand Oaks, CA, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Amgen, Inc., Thousand Oaks, CA, USA","institution_ids":["https://openalex.org/I1320553840"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040355091","display_name":"Marc G. Vervloet","orcid":"https://orcid.org/0000-0003-4607-9415","observed_orcids":["https://orcid.org/0000-0003-4607-9415"]},"institutions":[{"id":"https://openalex.org/I911458345","display_name":"Amsterdam UMC Location Vrije Universiteit Amsterdam","ror":"https://ror.org/00q6h8f30","country_code":"NL","type":"healthcare","lineage":["https://openalex.org/I4210151833","https://openalex.org/I911458345"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"Marc Vervloet","raw_affiliation_strings":["Department of Nephrology, VU University Medical Center, Amsterdam, The Netherlands"],"raw_orcid":"https://orcid.org/0000-0003-4607-9415","affiliations":[{"raw_affiliation_string":"Department of Nephrology, VU University Medical Center, Amsterdam, The Netherlands","institution_ids":["https://openalex.org/I911458345"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5057262840","display_name":"Rainer W. Oberbauer","orcid":"https://orcid.org/0000-0001-7544-6275","observed_orcids":["https://orcid.org/0000-0001-7544-6275"]},"institutions":[{"id":"https://openalex.org/I76134821","display_name":"Medical University of Vienna","ror":"https://ror.org/05n3x4p02","country_code":"AT","type":"education","lineage":["https://openalex.org/I76134821"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Rainer Oberbauer","raw_affiliation_strings":["Department of Nephrology, Medical University of Vienna, Vienna, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Medical University of Vienna, Vienna, Austria","institution_ids":["https://openalex.org/I76134821"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":11,"corresponding_author_ids":["https://openalex.org/A5008906136"],"corresponding_institution_ids":["https://openalex.org/I170897317","https://openalex.org/I4210126298","https://openalex.org/I4405286153"],"apc_list":{"value":2951,"currency":"EUR","value_usd":3335},"apc_paid":{"value":2951,"currency":"EUR","value_usd":3335},"fwci":3.3048,"has_fulltext":true,"cited_by_count":30,"citation_normalized_percentile":{"value":0.91848393,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"13","issue":"1","first_page":"75","last_page":"84"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/etelcalcetide","display_name":"etelcalcetide","score":1.0},{"id":"https://openalex.org/keywords/fgf23","display_name":"fibroblast growth factor 23","score":0.9829999804496765},{"id":"https://openalex.org/keywords/secondary-hyperparathyroidism","display_name":"secondary hyperparathyroidism","score":0.9980000257492065},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/calcimimetics","display_name":"calcimimetics","score":0.8960000276565552},{"id":"https://openalex.org/keywords/cinacalcet","display_name":"cinacalcet","score":0.9660000205039978},{"id":"https://openalex.org/keywords/parathyroid-hormone","display_name":"parathyroid hormone","score":0.9610000252723694},{"id":"https://openalex.org/keywords/serum-calcium","display_name":"serum calcium","score":0.6029999852180481},{"id":"https://openalex.org/keywords/serum-phosphorus","display_name":"serum phosphorus","score":0.8289999961853027},{"id":"https://openalex.org/keywords/bone-turnover-markers","display_name":"bone turnover markers","score":0.9229999780654907},{"id":"https://openalex.org/keywords/vitamin-d-supplementation","display_name":"vitamin D supplementation","score":0.8489999771118164},{"id":"https://openalex.org/keywords/hypocalcemia","display_name":"hypocalcemia","score":0.8109999895095825},{"id":"https://openalex.org/keywords/dialysate-calcium","display_name":"dialysate calcium","score":0.9580000042915344}],"concepts":[{"id":"https://openalex.org/C2780534505","wikidata":"https://www.wikidata.org/wiki/Q193978","display_name":"Cinacalcet","level":5,"score":0.8408059477806091},{"id":"https://openalex.org/C2780280601","wikidata":"https://www.wikidata.org/wiki/Q5018775","display_name":"Calcimimetic","level":5,"score":0.8277276754379272},{"id":"https://openalex.org/C2778838027","wikidata":"https://www.wikidata.org/wiki/Q3622611","display_name":"Secondary hyperparathyroidism","level":4,"score":0.8222675323486328},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8110949993133545},{"id":"https://openalex.org/C2781208988","wikidata":"https://www.wikidata.org/wiki/Q202476","display_name":"Parathyroid hormone","level":3,"score":0.6408542990684509},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.5591680407524109},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.5164690017700195},{"id":"https://openalex.org/C114276007","wikidata":"https://www.wikidata.org/wiki/Q14897899","display_name":"Fibroblast growth factor 23","level":4,"score":0.5139808058738708},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.505669355392456},{"id":"https://openalex.org/C2775945674","wikidata":"https://www.wikidata.org/wiki/Q1344835","display_name":"Hyperparathyroidism","level":2,"score":0.4966176152229309},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.48592010140419006},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.4387795627117157},{"id":"https://openalex.org/C519063684","wikidata":"https://www.wikidata.org/wiki/Q706","display_name":"Calcium","level":2,"score":0.28255391120910645},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.060893118381500244},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":8,"locations":[{"id":"doi:10.1093/ckj/sfz034","doi":"https://doi.org/10.1093/ckj/sfz034","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ckj/sfz034","pdf_url":"https://academic.oup.com/ckj/article-pdf/13/1/75/32500099/sfz034.pdf","source":{"id":"https://openalex.org/S117236744","display_name":"Clinical Kidney Journal","issn_l":"2048-8505","issn":["2048-8505","2048-8513"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Kidney Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:7025329","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/7025329","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clin Kidney J","raw_type":"Text"},{"id":"pmid:32082556","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/32082556","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical kidney journal","raw_type":"Journal Article"},{"id":"pmh:oai:pure.amsterdamumc.nl:openaire/a971f8fe-fa53-4b4b-953f-e8a014fa09d9","doi":null,"is_oa":true,"landing_page_url":"https://pure.amsterdamumc.nl/en/publications/a971f8fe-fa53-4b4b-953f-e8a014fa09d9","pdf_url":null,"source":{"id":"https://openalex.org/S7407055222","display_name":"Pure Amsterdam UMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Wolf, M, Block, G A, Chertow, G M, Cooper, K, Fouqueray, B, Moe, S M, Sun, Y, Tomlin, H, Vervloet, M & Oberbauer, R 2019, 'Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis', Clinical kidney journal, vol. 13, no. 1, pp. 75-84. https://doi.org/10.1093/ckj/sfz034","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:pure.atira.dk:openaire/b141b2f1-4b6e-41cf-ac37-ab2f7b02fe0a","doi":null,"is_oa":true,"landing_page_url":"https://www.scopus.com/pages/publications/85079929108","pdf_url":null,"source":{"id":"https://openalex.org/S7407055350","display_name":"Amsterdam UMC (VU Amsterdam) - Institutional Repository","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Wolf, M, Block, G A, Chertow, G M, Cooper, K, Fouqueray, B, Moe, S M, Sun, Y, Tomlin, H, Vervloet, M & Oberbauer, R 2019, 'Effects of etelcalcetide on fibroblast growth factor 23 in patients with secondary hyperparathyroidism receiving hemodialysis', Clinical kidney journal, vol. 13, no. 1, pp. 75-84. https://doi.org/10.1093/ckj/sfz034","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:scholarworks.iupui.edu:1805/22493","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1805/22493","pdf_url":null,"source":{"id":"https://openalex.org/S4306402593","display_name":"Purdue University Indianapolis (Indiana University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I592451","host_organization_name":"Indiana University","host_organization_lineage":["https://openalex.org/I592451"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"PMC","raw_type":"Article"},{"id":"pmh:vumc:oai:pure.atira.dk:publications/b141b2f1-4b6e-41cf-ac37-ab2f7b02fe0a","doi":null,"is_oa":true,"landing_page_url":"https://research.vumc.nl/en/publications/b141b2f1-4b6e-41cf-ac37-ab2f7b02fe0a","pdf_url":null,"source":{"id":"https://openalex.org/S4306401843","display_name":"Data Archiving and Networked Services (DANS)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1322597698","host_organization_name":"Royal Netherlands Academy of Arts and Sciences","host_organization_lineage":["https://openalex.org/I1322597698"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Clinical kidney journal, 13(1), 75 - 84. Oxford University Press","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:3032110557","doi":null,"is_oa":false,"landing_page_url":"https://scholarworks.iupui.edu/bitstream/1805/22493/1/sfz034.pdf","pdf_url":null,"source":{"id":"https://openalex.org/S4306522653","display_name":"PMC","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PMC","raw_type":null}],"best_oa_location":{"id":"doi:10.1093/ckj/sfz034","doi":"https://doi.org/10.1093/ckj/sfz034","is_oa":true,"landing_page_url":"https://doi.org/10.1093/ckj/sfz034","pdf_url":"https://academic.oup.com/ckj/article-pdf/13/1/75/32500099/sfz034.pdf","source":{"id":"https://openalex.org/S117236744","display_name":"Clinical Kidney Journal","issn_l":"2048-8505","issn":["2048-8505","2048-8513"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","norway-1","oarl","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Kidney Journal","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4474384861","display_name":null,"funder_award_id":"20120229","funder_id":"https://openalex.org/F4320307105","funder_display_name":"Amgen"},{"id":"https://openalex.org/G5102611551","display_name":null,"funder_award_id":"NCT01785849","funder_id":"https://openalex.org/F4320307105","funder_display_name":"Amgen"},{"id":"https://openalex.org/G6200843717","display_name":null,"funder_award_id":"NCT01788046","funder_id":"https://openalex.org/F4320307105","funder_display_name":"Amgen"},{"id":"https://openalex.org/G8135119143","display_name":null,"funder_award_id":"NCT1896232","funder_id":"https://openalex.org/F4320307105","funder_display_name":"Amgen"},{"id":"https://openalex.org/G8636473161","display_name":null,"funder_award_id":"20120360","funder_id":"https://openalex.org/F4320307105","funder_display_name":"Amgen"},{"id":"https://openalex.org/G8837340533","display_name":null,"funder_award_id":"20120230","funder_id":"https://openalex.org/F4320307105","funder_display_name":"Amgen"}],"funders":[{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2941223368.pdf","grobid_xml":"https://content.openalex.org/works/W2941223368.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W1562538838","https://openalex.org/W1674343883","https://openalex.org/W1964311752","https://openalex.org/W1969924373","https://openalex.org/W1973274158","https://openalex.org/W1973733126","https://openalex.org/W1977645780","https://openalex.org/W1983098935","https://openalex.org/W1985499182","https://openalex.org/W1988897099","https://openalex.org/W2001405719","https://openalex.org/W2035667662","https://openalex.org/W2035803962","https://openalex.org/W2041242683","https://openalex.org/W2042639382","https://openalex.org/W2056163033","https://openalex.org/W2064232755","https://openalex.org/W2067490907","https://openalex.org/W2073936776","https://openalex.org/W2076092560","https://openalex.org/W2107420262","https://openalex.org/W2107471648","https://openalex.org/W2111387279","https://openalex.org/W2118752987","https://openalex.org/W2127828880","https://openalex.org/W2131843552","https://openalex.org/W2136486000","https://openalex.org/W2138484858","https://openalex.org/W2139989191","https://openalex.org/W2143470199","https://openalex.org/W2145901046","https://openalex.org/W2158482269","https://openalex.org/W2167092665","https://openalex.org/W2168867186","https://openalex.org/W2170092490","https://openalex.org/W2320786490","https://openalex.org/W2419509159","https://openalex.org/W2521028081","https://openalex.org/W2527550773","https://openalex.org/W2550323116","https://openalex.org/W2565056950","https://openalex.org/W2571985472","https://openalex.org/W2700576091","https://openalex.org/W2766218357","https://openalex.org/W2769367888","https://openalex.org/W6646806199"],"related_works":["https://openalex.org/W2617922689","https://openalex.org/W4283375521","https://openalex.org/W2804160160","https://openalex.org/W2900949607","https://openalex.org/W7064212829","https://openalex.org/W4398187762","https://openalex.org/W3137504235","https://openalex.org/W2805174745","https://openalex.org/W2621333588","https://openalex.org/W2766218357"],"abstract_inverted_index":{"Abstract":[0],"Background":[1],"Etelcalcetide":[2,121],"is":[3],"an":[4],"intravenous":[5],"calcimimetic":[6],"approved":[7],"for":[8],"treatment":[9],"of":[10,42,50,61,118,135,191,205,218,230],"secondary":[11,48],"hyperparathyroidism":[12],"(sHPT)":[13],"in":[14,81,90,92,96,169,175,195,241,264],"patients":[15,242,254],"receiving":[16,85,245],"hemodialysis.":[17,86],"Besides":[18],"lowering":[19],"parathyroid":[20],"hormone":[21],"(PTH),":[22],"etelcalcetide":[23,62,72,237],"also":[24,105],"significantly":[25,138],"reduces":[26],"fibroblast":[27],"growth":[28],"factor":[29],"23":[30],"(FGF23),":[31],"but":[32,179,207],"the":[33,51,57,115,133,136,202,227,249],"mechanisms":[34],"are":[35],"unknown.":[36],"Methods":[37],"To":[38],"investigate":[39],"potential":[40],"mediators":[41],"etelcalcetide-induced":[43],"FGF23":[44,91,123,170,240],"reduction,":[45],"we":[46],"performed":[47],"analyses":[49],"26-week":[52],"randomized":[53],"trials":[54],"that":[55,236,248],"compared":[56],"effects":[58,117,229],"on":[59],"PTH":[60],"(n":[63,68,73,78],"=":[64,69,74,79],"509)":[65],"versus":[66,76,146,160,212,221],"placebo":[67,141],"514)":[70],"and":[71,100,154,177,190,215,247],"340)":[75],"cinacalcet":[77,155],"343)":[80],"adults":[82],"with":[83,173,181,184,243],"sHPT":[84,244],"We":[87,104],"analyzed":[88],"changes":[89,95],"relation":[93],"to":[94,132,144,149,158,163],"PTH,":[97],"calcium,":[98],"phosphate":[99],"bone":[101,185],"turnover":[102,186],"markers.":[103],"investigated":[106],"how":[107],"concomitant":[108,196,257],"treatments":[109,258],"aimed":[110,259],"at":[111,260],"mitigating":[112,261],"hypocalcemia":[113],"altered":[114],"FGF23-lowering":[116,203,228],"etelcalcetide.":[119,231],"Results":[120],"reduced":[122],"[median":[124],"%":[125],"change":[126],"(quartile":[127],"1\u2013quartile":[128],"3)]":[129],"from":[130],"baseline":[131],"end":[134],"trial":[137],"more":[139],"than":[140],"[\u201356%":[142],"(\u201385":[143],"\u20137)":[145],"+2%":[147],"(\u201340":[148],"+65);":[150],"P":[151,165],"<":[152,166],"0.001]":[153],"[\u201368%":[156],"(\u201387":[157],"\u201326)":[159],"\u201341%":[161],"(\u201376":[162],"+25);":[164],"0.001].":[167],"Reductions":[168],"correlated":[171],"strongly":[172],"reductions":[174],"calcium":[176,210,219],"phosphate,":[178],"not":[180,225],"PTH;":[182],"correlations":[183],"markers":[187],"were":[188],"inconsistent":[189],"borderline":[192],"significance.":[193],"Increases":[194],"vitamin":[197],"D":[198],"administration":[199],"partially":[200],"attenuated":[201],"effect":[204,250],"etelcalcetide,":[206],"increased":[208,216],"dialysate":[209],"concentration":[211],"no":[213,222],"increase":[214,223],"dose":[217],"supplementation":[220],"did":[224],"attenuate":[226],"Conclusion":[232],"These":[233],"data":[234],"suggest":[235],"potently":[238],"lowers":[239],"hemodialysis":[246],"remains":[251],"detectable":[252],"among":[253],"who":[255],"receive":[256],"treatment-associated":[262],"decreases":[263],"serum":[265],"calcium.":[266]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2019-05-03T00:00:00"}
