{"id":"https://openalex.org/W2940530809","doi":"https://doi.org/10.1097/mph.0000000000001490","title":"Systemic Lupus Erythematosus, Evans Syndrome, and Neurofibromatosis: An Unusual Combination in Pediatric Patient","display_name":"Systemic Lupus Erythematosus, Evans Syndrome, and Neurofibromatosis: An Unusual Combination in Pediatric Patient","publication_year":2019,"publication_date":"2019-04-27","ids":{"openalex":"https://openalex.org/W2940530809","doi":"https://doi.org/10.1097/mph.0000000000001490","mag":"2940530809","pmid":"https://pubmed.ncbi.nlm.nih.gov/31033790"},"language":"en","primary_location":{"id":"doi:10.1097/mph.0000000000001490","doi":"https://doi.org/10.1097/mph.0000000000001490","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mph.0000000000001490","pdf_url":null,"source":{"id":"https://openalex.org/S15952725","display_name":"Journal of Pediatric Hematology/Oncology","issn_l":"1077-4114","issn":["1077-4114","1536-3678"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Hematology/Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5087189305","display_name":"Amy M. Moskop","orcid":"https://orcid.org/0000-0002-5110-004X","observed_orcids":["https://orcid.org/0000-0002-5110-004X"]},"institutions":[{"id":"https://openalex.org/I126218986","display_name":"Children's Hospital of Wisconsin","ror":"https://ror.org/049cbmb74","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I126218986"]},{"id":"https://openalex.org/I204308271","display_name":"Medical College of Wisconsin","ror":"https://ror.org/00qqv6244","country_code":"US","type":"education","lineage":["https://openalex.org/I204308271"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Amy Moskop","raw_affiliation_strings":["Department of Pediatrics","Present address: Amy Moskop, MD, Department of Pediatrics, Medical College of Wisconsin, Children's Hospital of Wisconsin, 8915 W Connell Ct, Milwaukee, WI 53226"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics","institution_ids":[]},{"raw_affiliation_string":"Present address: Amy Moskop, MD, Department of Pediatrics, Medical College of Wisconsin, Children's Hospital of Wisconsin, 8915 W Connell Ct, Milwaukee, WI 53226","institution_ids":["https://openalex.org/I126218986","https://openalex.org/I204308271"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031581569","display_name":"Austin M. Dalrymple","orcid":"https://orcid.org/0000-0002-3376-4256","observed_orcids":["https://orcid.org/0000-0002-3376-4256"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Austin Dalrymple","raw_affiliation_strings":["Division of Adult & Pediatric Rheumatology"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Adult & Pediatric Rheumatology","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5005403092","display_name":"Leili Dolatshahi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1325203003","display_name":"Cardinal Glennon Children\u2019s Medical Center","ror":"https://ror.org/00jq51013","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1325203003","https://openalex.org/I2801580383"]},{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Leili Dolatshahi","raw_affiliation_strings":["Division of Pediatric Hematology-Oncology, Saint Louis University School of Medicine, SSM Health Cardinal Glennon Children\u2019s Hospital, St Louis, MO"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Pediatric Hematology-Oncology, Saint Louis University School of Medicine, SSM Health Cardinal Glennon Children\u2019s Hospital, St Louis, MO","institution_ids":["https://openalex.org/I1325203003","https://openalex.org/I47838141"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5087189305"],"corresponding_institution_ids":["https://openalex.org/I126218986","https://openalex.org/I204308271"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":5,"citation_normalized_percentile":{"value":0.05553015,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"42","issue":"4","first_page":"e244","last_page":"e247"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/systemic-lupus-erythematosus","display_name":"systemic lupus erythematosus","score":1.0},{"id":"https://openalex.org/keywords/evans-syndrome","display_name":"Evans syndrome","score":0.9980000257492065},{"id":"https://openalex.org/keywords/neurofibromatosis-type-1","display_name":"neurofibromatosis type 1","score":0.9819999933242798},{"id":"https://openalex.org/keywords/immune-mediated-thrombocytopenia","display_name":"immune-mediated thrombocytopenia","score":0.8799999952316284},{"id":"https://openalex.org/keywords/immune-mediated-anemia","display_name":"immune-mediated anemia","score":0.8519999980926514},{"id":"https://openalex.org/keywords/immune-mediated-cytopenia","display_name":"immune-mediated cytopenia","score":0.8059999942779541},{"id":"https://openalex.org/keywords/autoimmune-disease","display_name":"autoimmune disease","score":0.5709999799728394},{"id":"https://openalex.org/keywords/pediatric-patients","display_name":"pediatric patients","score":0.6949999928474426},{"id":"https://openalex.org/keywords/comorbidity","display_name":"comorbidities","score":0.7070000171661377}],"concepts":[{"id":"https://openalex.org/C2781128166","wikidata":"https://www.wikidata.org/wiki/Q3109873","display_name":"Evans syndrome","level":4,"score":0.8455327153205872},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8387079238891602},{"id":"https://openalex.org/C2778984943","wikidata":"https://www.wikidata.org/wiki/Q847605","display_name":"Neurofibromatosis","level":2,"score":0.663188099861145},{"id":"https://openalex.org/C2777385706","wikidata":"https://www.wikidata.org/wiki/Q28814","display_name":"Autoimmune hemolytic anemia","level":3,"score":0.50422203540802},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4997258186340332},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4987020492553711},{"id":"https://openalex.org/C2779075594","wikidata":"https://www.wikidata.org/wiki/Q8084905","display_name":"Autoimmune disease","level":3,"score":0.4851256310939789},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4696865379810333},{"id":"https://openalex.org/C2778248108","wikidata":"https://www.wikidata.org/wiki/Q5445","display_name":"Anemia","level":2,"score":0.4584770202636719},{"id":"https://openalex.org/C2777805810","wikidata":"https://www.wikidata.org/wiki/Q1047559","display_name":"Hypogammaglobulinemia","level":3,"score":0.44517287611961365},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.42808955907821655},{"id":"https://openalex.org/C2775915377","wikidata":"https://www.wikidata.org/wiki/Q188297","display_name":"Lupus erythematosus","level":3,"score":0.41772374510765076},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.15196916460990906},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.13038939237594604},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.12737154960632324}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000744","descriptor_name":"Anemia, Hemolytic, Autoimmune","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D000744","descriptor_name":"Anemia, Hemolytic, Autoimmune","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D000744","descriptor_name":"Anemia, Hemolytic, Autoimmune","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D008180","descriptor_name":"Lupus Erythematosus, Systemic","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D009456","descriptor_name":"Neurofibromatosis 1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D009456","descriptor_name":"Neurofibromatosis 1","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D009456","descriptor_name":"Neurofibromatosis 1","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true},{"descriptor_ui":"D013921","descriptor_name":"Thrombocytopenia","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D013921","descriptor_name":"Thrombocytopenia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D013921","descriptor_name":"Thrombocytopenia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1097/mph.0000000000001490","doi":"https://doi.org/10.1097/mph.0000000000001490","is_oa":false,"landing_page_url":"https://doi.org/10.1097/mph.0000000000001490","pdf_url":null,"source":{"id":"https://openalex.org/S15952725","display_name":"Journal of Pediatric Hematology/Oncology","issn_l":"1077-4114","issn":["1077-4114","1536-3678"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-40","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Pediatric Hematology/Oncology","raw_type":"journal-article"},{"id":"pmid:31033790","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31033790","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of pediatric hematology/oncology","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":13,"referenced_works":["https://openalex.org/W2018955763","https://openalex.org/W2031229113","https://openalex.org/W2038137985","https://openalex.org/W2063621190","https://openalex.org/W2074310430","https://openalex.org/W2074546201","https://openalex.org/W2075376590","https://openalex.org/W2089372154","https://openalex.org/W2136512246","https://openalex.org/W2159860161","https://openalex.org/W2161527441","https://openalex.org/W2303297332","https://openalex.org/W3027384253"],"related_works":["https://openalex.org/W2075376590","https://openalex.org/W2303297332","https://openalex.org/W2553167521","https://openalex.org/W4385262685","https://openalex.org/W2879198369","https://openalex.org/W2232652439","https://openalex.org/W7164127061","https://openalex.org/W249342120","https://openalex.org/W2988890259","https://openalex.org/W3097657036"],"abstract_inverted_index":{"Systemic":[0],"lupus":[1],"erythematosus":[2],"(SLE)":[3],"is":[4,23,39,66],"an":[5],"autoimmune":[6,37],"disease":[7],"that":[8],"affects":[9],"multiple":[10],"organ":[11],"systems.":[12],"Patients":[13],"can":[14],"have":[15],"hematologic":[16],"manifestations,":[17],"including":[18],"Evans":[19],"syndrome":[20],"(ES),":[21],"which":[22],"characterized":[24],"by":[25],"immune-mediated":[26,63],"thrombocytopenia":[27],"and":[28,52,65,71,80,82,98],"anemia.":[29],"The":[30],"association":[31],"of":[32,50,56,78,92,95],"neurofibromatosis":[33],"1":[34],"(NF1)":[35],"with":[36,62,68],"disorders":[38,51],"rarely":[40],"reported.":[41],"We":[42],"will":[43],"review":[44],"the":[45,93],"literature":[46],"for":[47],"this":[48],"combination":[49,94],"describe":[53],"a":[54,57],"case":[55],"16-year-old":[58],"girl":[59],"who":[60],"presents":[61],"cytopenias":[64],"diagnosed":[67],"SLE,":[69,96],"ES,":[70,97],"NF1.":[72,99],"There":[73,88],"are":[74,85,89],"7":[75],"reported":[76],"cases":[77],"SLE":[79],"NF1":[81],"only":[83],"2":[84],"pediatric":[86],"cases.":[87],"no":[90],"reports":[91]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-05-03T00:00:00"}