{"id":"https://openalex.org/W2940061493","doi":"https://doi.org/10.4244/eij-d-17-00728","title":"Acute thrombogenicity of fluoropolymer-coated versus biodegradable and polymer-free stents","display_name":"Acute thrombogenicity of fluoropolymer-coated versus biodegradable and polymer-free stents","publication_year":2019,"publication_date":"2019-03-01","ids":{"openalex":"https://openalex.org/W2940061493","doi":"https://doi.org/10.4244/eij-d-17-00728","mag":"2940061493","pmid":"https://pubmed.ncbi.nlm.nih.gov/29619983"},"language":"en","primary_location":{"id":"doi:10.4244/eij-d-17-00728","doi":"https://doi.org/10.4244/eij-d-17-00728","is_oa":false,"landing_page_url":"https://doi.org/10.4244/eij-d-17-00728","pdf_url":null,"source":{"id":"https://openalex.org/S104576203","display_name":"EuroIntervention","issn_l":"1774-024X","issn":["1774-024X","1969-6213"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4323238086","host_organization_name":"European Association of Percutaneous Cardiovascular Interventions","host_organization_lineage":["https://openalex.org/P4323238086"],"host_organization_lineage_names":["European Association of Percutaneous Cardiovascular Interventions"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EuroIntervention","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5084939491","display_name":"Sho Torii","orcid":"https://orcid.org/0000-0002-5934-0427","observed_orcids":["https://orcid.org/0000-0002-5934-0427"]},"institutions":[{"id":"https://openalex.org/I4210135350","display_name":"CVPath Institute","ror":"https://ror.org/03gbzhd34","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210135350"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sho Torii","raw_affiliation_strings":["CVPath Institute, Inc., Gaithersburg, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CVPath Institute, Inc., Gaithersburg, MD, USA","institution_ids":["https://openalex.org/I4210135350"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089277479","display_name":"Qi Cheng","orcid":"https://orcid.org/0000-0002-2107-6253","observed_orcids":["https://orcid.org/0000-0002-2107-6253"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Qi Cheng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089807386","display_name":"Hiroyoshi Mori","orcid":"https://orcid.org/0000-0001-6060-3485","observed_orcids":["https://orcid.org/0000-0001-6060-3485"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Hiroyoshi Mori","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051088058","display_name":"Michael Joseph Lipinski","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael J. Lipinski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050618356","display_name":"Eduardo Acampado","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Eduardo Acampado","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017758543","display_name":"Laura E. Leigh Perkins","orcid":"https://orcid.org/0000-0002-0064-4557","observed_orcids":["https://orcid.org/0000-0002-0064-4557"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Laura E.L. Perkins","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110435837","display_name":"Syed Hossainy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Syed F. Hossainy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037117449","display_name":"Stephen Pacetti","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stephen D. Pacetti","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068524141","display_name":"Frank D. Kolodgie","orcid":"https://orcid.org/0000-0002-6007-2044","observed_orcids":["https://orcid.org/0000-0002-6007-2044"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frank D. Kolodgie","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071287538","display_name":"Renu Virmani","orcid":"https://orcid.org/0000-0003-1879-0015","observed_orcids":["https://orcid.org/0000-0003-1879-0015"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Renu Virmani","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5062478846","display_name":"Aloke Virmani Finn","orcid":"https://orcid.org/0000-0003-0359-0184","observed_orcids":["https://orcid.org/0000-0003-0359-0184"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Aloke V. Finn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":6.2028,"has_fulltext":false,"cited_by_count":39,"citation_normalized_percentile":{"value":0.97248891,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":90,"max":99},"biblio":{"volume":"14","issue":"16","first_page":"1685","last_page":"1693"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10859","display_name":"Polymer Surface Interaction Studies","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2508","display_name":"Surfaces, Coatings and Films"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/fluoropolymer-coatings","display_name":"fluoropolymer coatings","score":0.8769999742507935},{"id":"https://openalex.org/keywords/stent-thrombosis","display_name":"stent thrombosis","score":0.8740000128746033},{"id":"https://openalex.org/keywords/everolimus-eluting-stent","display_name":"everolimus-eluting stent","score":0.9089999794960022},{"id":"https://openalex.org/keywords/biodegradable-polymer-stents","display_name":"biodegradable polymer stents","score":0.7689999938011169},{"id":"https://openalex.org/keywords/sirolimus-eluting-stent","display_name":"sirolimus-eluting stent","score":0.9860000014305115},{"id":"https://openalex.org/keywords/polymer-free-drug-eluting-stents","display_name":"polymer-free drug-eluting stents","score":0.7540000081062317},{"id":"https://openalex.org/keywords/platelet-adhesion","display_name":"platelet adhesion","score":0.7609999775886536},{"id":"https://openalex.org/keywords/thromboresistance","display_name":"thromboresistance","score":0.8610000014305115},{"id":"https://openalex.org/keywords/bare-metal-stents","display_name":"bare-metal stents","score":0.9020000100135803},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.4560000002384186}],"concepts":[{"id":"https://openalex.org/C2780708225","wikidata":"https://www.wikidata.org/wiki/Q1818706","display_name":"Fluoropolymer","level":3,"score":0.8567439317703247},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8421803712844849},{"id":"https://openalex.org/C2776649359","wikidata":"https://www.wikidata.org/wiki/Q7798338","display_name":"Thrombogenicity","level":3,"score":0.7912076115608215},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.5628369450569153},{"id":"https://openalex.org/C2778583881","wikidata":"https://www.wikidata.org/wiki/Q1325542","display_name":"Stent","level":2,"score":0.5125086307525635},{"id":"https://openalex.org/C45211672","wikidata":"https://www.wikidata.org/wiki/Q4119016","display_name":"Biodegradable polymer","level":3,"score":0.454234778881073},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.45311933755874634},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.32959800958633423},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.32726210355758667},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.29357197880744934},{"id":"https://openalex.org/C521977710","wikidata":"https://www.wikidata.org/wiki/Q81163","display_name":"Polymer","level":2,"score":0.2335895597934723},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.08408492803573608},{"id":"https://openalex.org/C159985019","wikidata":"https://www.wikidata.org/wiki/Q181790","display_name":"Composite material","level":1,"score":0.07409560680389404}],"mesh":[{"descriptor_ui":"D000068338","descriptor_name":"Everolimus","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011108","descriptor_name":"Polymers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013552","descriptor_name":"Swine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013927","descriptor_name":"Thrombosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015607","descriptor_name":"Stents","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.4244/eij-d-17-00728","doi":"https://doi.org/10.4244/eij-d-17-00728","is_oa":false,"landing_page_url":"https://doi.org/10.4244/eij-d-17-00728","pdf_url":null,"source":{"id":"https://openalex.org/S104576203","display_name":"EuroIntervention","issn_l":"1774-024X","issn":["1774-024X","1969-6213"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4323238086","host_organization_name":"European Association of Percutaneous Cardiovascular Interventions","host_organization_lineage":["https://openalex.org/P4323238086"],"host_organization_lineage_names":["European Association of Percutaneous Cardiovascular Interventions"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EuroIntervention","raw_type":"journal-article"},{"id":"pmid:29619983","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/29619983","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":28,"referenced_works":["https://openalex.org/W146325010","https://openalex.org/W1184289734","https://openalex.org/W1527614413","https://openalex.org/W1595078900","https://openalex.org/W1968528328","https://openalex.org/W1976855765","https://openalex.org/W2012757283","https://openalex.org/W2033563712","https://openalex.org/W2040576110","https://openalex.org/W2043695623","https://openalex.org/W2082873393","https://openalex.org/W2125291234","https://openalex.org/W2154567759","https://openalex.org/W2161895979","https://openalex.org/W2171056475","https://openalex.org/W2180983922","https://openalex.org/W2229573961","https://openalex.org/W2312771026","https://openalex.org/W2337954949","https://openalex.org/W2410639616","https://openalex.org/W2462320648","https://openalex.org/W2464247093","https://openalex.org/W2465123542","https://openalex.org/W2546366038","https://openalex.org/W2556765078","https://openalex.org/W2759236937","https://openalex.org/W2760659611","https://openalex.org/W2768525260"],"related_works":["https://openalex.org/W1184289734","https://openalex.org/W3012092449","https://openalex.org/W2766552995","https://openalex.org/W2074694449","https://openalex.org/W2337954949","https://openalex.org/W2017813795","https://openalex.org/W2744383172","https://openalex.org/W2049861924","https://openalex.org/W2988154060","https://openalex.org/W2346719963"],"abstract_inverted_index":{"AIMS:":[0],"Durable":[1],"fluoropolymer-coated":[2,65],"everolimus-eluting":[3],"stents":[4,17,48,82,97,108,134,142],"(FP-EES)":[5],"have":[6],"shown":[7],"lower":[8,145],"rates":[9,216],"of":[10,27,36,46,106],"stent":[11],"thrombosis":[12],"(ST)":[13],"versus":[14],"bare":[15],"metal":[16],"(BMS)":[18],"and":[19,88,111,120,175,194],"first-generation":[20],"bioabsorbable":[21],"polymer":[22,80],"(BP)":[23],"DES.":[24],"The":[25],"aim":[26],"the":[28,33,37,165,179],"study":[29],"was":[30,114,127],"to":[31,192,195],"evaluate":[32],"specific":[34],"role":[35],"FP":[38],"in":[39,51,217],"thromboresistance.":[40],"METHODS":[41],"AND":[42],"RESULTS:":[43],"A":[44],"total":[45],"57":[47],"were":[49,109,135],"assessed":[50],"three":[52],"separate":[53],"ex":[54],"vivo":[55],"swine":[56],"arteriovenous":[57],"shunt":[58,62,73,90],"model":[59],"experiments":[60],"(first":[61],"experiment,":[63,74,91],"custom-made":[64],"BMS":[66,69,85,100,150,176,193],"[FP-only]":[67],"vs.":[68,76,84,93,99],"[n=8":[70,86],"each];":[71,87],"second":[72],"FP-EES":[75,92,162],"abluminally":[77],"coated":[78],"biodegradable":[79],"sirolimus-eluting":[81],"[BP-SES]":[83],"third":[89],"polymer-free":[94,196],"Biolimus":[95],"A9-coated":[96],"[PF-BCS]":[98],"[n=6":[101],"each]).":[102],"After":[103],"one":[104,208],"hour":[105],"circulation,":[107],"bisected,":[110],"each":[112],"half":[113],"dual-immunostained":[115],"using":[116],"a":[117,121],"platelet":[118,146,167],"cocktail":[119],"marker":[122],"for":[123,211],"inflammation.":[124],"Antibody":[125],"staining":[126],"visualised":[128],"by":[129,137],"confocal":[130],"microscopy.":[131,140],"In":[132],"addition,":[133],"evaluated":[136],"scanning":[138],"electron":[139],"FP-only":[141],"showed":[143],"significantly":[144,180],"adherence":[147,168],"compared":[148,169],"with":[149,157,170,178],"(%":[151],"fluorescence-positive":[152],"area:":[153],"FP-only=1.8%,":[154],"BMS=5.6%,":[155],"p=0.047)":[156],"similar":[158],"inflammatory":[159,182],"cell":[160,183],"density.":[161,184],"also":[163],"demonstrated":[164],"lowest":[166,181],"BP-SES":[171],"(p=0.056),":[172],"PF-BCS":[173],"(p=0.013)":[174],"(p=0.003)":[177],"CONCLUSIONS:":[185],"Fluoropolymer":[186],"coating":[187],"imparts":[188],"greater":[189],"thromboresistance":[190],"relative":[191],"DES":[197],"designs,":[198],"which":[199],"reflects":[200],"an":[201],"unique":[202],"phenomenon":[203],"known":[204],"as":[205],"fluoropassivation,":[206],"representing":[207],"proposed":[209],"mechanism":[210],"clinically":[212],"observed":[213],"low":[214],"ST":[215],"FP-EES.":[218]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":11},{"year":2020,"cited_by_count":8},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-04-25T00:00:00"}