{"id":"https://openalex.org/W2937795185","doi":"https://doi.org/10.3390/microorganisms7040104","title":"Probiotics: If It Does Not Help It Does Not Do Any Harm. Really?","display_name":"Probiotics: If It Does Not Help It Does Not Do Any Harm. Really?","publication_year":2019,"publication_date":"2019-04-11","ids":{"openalex":"https://openalex.org/W2937795185","doi":"https://doi.org/10.3390/microorganisms7040104","mag":"2937795185","pmid":"https://pubmed.ncbi.nlm.nih.gov/30979072","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6517882"},"language":"en","primary_location":{"id":"doi:10.3390/microorganisms7040104","doi":"https://doi.org/10.3390/microorganisms7040104","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/microorganisms7040104","pdf_url":"https://www.mdpi.com/2076-2607/7/4/104/pdf?version=1555839931","source":{"id":"https://openalex.org/S4210222090","display_name":"Microorganisms","issn_l":"2076-2607","issn":["2076-2607"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microorganisms","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2076-2607/7/4/104/pdf?version=1555839931","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005136857","display_name":"Aaron Lerner","orcid":"https://orcid.org/0000-0002-6779-4090","observed_orcids":["https://orcid.org/0000-0002-6779-4090"]},"institutions":[{"id":"https://openalex.org/I174306211","display_name":"Technion \u2013 Israel Institute of Technology","ror":"https://ror.org/03qryx823","country_code":"IL","type":"education","lineage":["https://openalex.org/I174306211"]}],"countries":["IL"],"is_corresponding":true,"raw_author_name":"Aaron Lerner","raw_affiliation_strings":["AESKU.KIPP Institute, 55234 Wendelsheim, Germany","B. Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AESKU.KIPP Institute, 55234 Wendelsheim, Germany","institution_ids":[]},{"raw_affiliation_string":"B. Rappaport School of Medicine, Technion-Israel Institute of Technology, Haifa 3200003, Israel","institution_ids":["https://openalex.org/I174306211"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074738902","display_name":"Yehuda Shoenfeld","orcid":"https://orcid.org/0000-0003-2802-4090","observed_orcids":["https://orcid.org/0000-0003-2802-4090","https://orcid.org/0000-0003-0185-9637"]},"institutions":[{"id":"https://openalex.org/I16391192","display_name":"Tel Aviv University","ror":"https://ror.org/04mhzgx49","country_code":"IL","type":"education","lineage":["https://openalex.org/I16391192"]},{"id":"https://openalex.org/I2799810450","display_name":"Sheba Medical Center","ror":"https://ror.org/020rzx487","country_code":"IL","type":"healthcare","lineage":["https://openalex.org/I2799810450"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Yehuda Shoenfeld","raw_affiliation_strings":["The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 5262000, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Tel Hashomer, Sackler Faculty of Medicine, Tel-Aviv University, Tel Aviv 5262000, Israel","institution_ids":["https://openalex.org/I16391192","https://openalex.org/I2799810450"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5113707330","display_name":"Torsten Matthias","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Torsten Matthias","raw_affiliation_strings":["AESKU.KIPP Institute, 55234 Wendelsheim, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"AESKU.KIPP Institute, 55234 Wendelsheim, Germany","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5005136857"],"corresponding_institution_ids":["https://openalex.org/I174306211"],"apc_list":{"value":1200,"currency":"CHF","value_usd":1216},"apc_paid":{"value":1200,"currency":"CHF","value_usd":1216},"fwci":1.1606,"has_fulltext":true,"cited_by_count":120,"citation_normalized_percentile":{"value":0.73289902,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":97,"max":100},"biblio":{"volume":"7","issue":"4","first_page":"104","last_page":"104"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10141","display_name":"Probiotics and Fermented Foods","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/probiotics","display_name":"probiotics","score":1.0},{"id":"https://openalex.org/keywords/probiotic-safety","display_name":"probiotic safety","score":0.9739999771118164},{"id":"https://openalex.org/keywords/probiotic-efficacy","display_name":"probiotic efficacy","score":0.7770000100135803},{"id":"https://openalex.org/keywords/study-design-flaws","display_name":"study design flaws","score":0.6349999904632568},{"id":"https://openalex.org/keywords/reporting-quality","display_name":"reporting quality","score":0.6650000214576721},{"id":"https://openalex.org/keywords/transparency","display_name":"transparency","score":0.42800000309944153},{"id":"https://openalex.org/keywords/virulence-factors","display_name":"virulence factors","score":0.7110000252723694},{"id":"https://openalex.org/keywords/gut-microbiota","display_name":"gut microbiota","score":0.7360000014305115},{"id":"https://openalex.org/keywords/mechanism-of-action","display_name":"mechanism of action","score":0.6269999742507935},{"id":"https://openalex.org/keywords/probiotic-regulation","display_name":"probiotic regulation","score":0.828000009059906},{"id":"https://openalex.org/keywords/human-microbiome","display_name":"human microbiome","score":0.7770000100135803}],"concepts":[{"id":"https://openalex.org/C2777363581","wikidata":"https://www.wikidata.org/wiki/Q15098235","display_name":"Harm","level":2,"score":0.7474962472915649},{"id":"https://openalex.org/C2780255968","wikidata":"https://www.wikidata.org/wiki/Q1816730","display_name":"Probiotic","level":3,"score":0.5896978974342346},{"id":"https://openalex.org/C7991579","wikidata":"https://www.wikidata.org/wiki/Q17955","display_name":"Criticism","level":2,"score":0.5708785653114319},{"id":"https://openalex.org/C2780233690","wikidata":"https://www.wikidata.org/wiki/Q535347","display_name":"Transparency (behavior)","level":2,"score":0.5612552165985107},{"id":"https://openalex.org/C84976871","wikidata":"https://www.wikidata.org/wiki/Q2015673","display_name":"Openness to experience","level":2,"score":0.5019636154174805},{"id":"https://openalex.org/C112930515","wikidata":"https://www.wikidata.org/wiki/Q4389547","display_name":"Risk analysis (engineering)","level":1,"score":0.4953867197036743},{"id":"https://openalex.org/C2987857752","wikidata":"https://www.wikidata.org/wiki/Q12147","display_name":"Human health","level":2,"score":0.4619370698928833},{"id":"https://openalex.org/C30772137","wikidata":"https://www.wikidata.org/wiki/Q5164762","display_name":"Consumption (sociology)","level":2,"score":0.46170762181282043},{"id":"https://openalex.org/C2780791683","wikidata":"https://www.wikidata.org/wiki/Q846785","display_name":"Action (physics)","level":2,"score":0.4494726359844208},{"id":"https://openalex.org/C143121216","wikidata":"https://www.wikidata.org/wiki/Q1330402","display_name":"Microbiome","level":2,"score":0.4351918399333954},{"id":"https://openalex.org/C144133560","wikidata":"https://www.wikidata.org/wiki/Q4830453","display_name":"Business","level":0,"score":0.3867272734642029},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3647822141647339},{"id":"https://openalex.org/C56739046","wikidata":"https://www.wikidata.org/wiki/Q192060","display_name":"Knowledge management","level":1,"score":0.35556310415267944},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.32180604338645935},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.2726996839046478},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.23784464597702026},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.21868550777435303},{"id":"https://openalex.org/C17744445","wikidata":"https://www.wikidata.org/wiki/Q36442","display_name":"Political science","level":0,"score":0.2055324912071228},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.20541933178901672},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.20200654864311218},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.1495766043663025},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.12225860357284546},{"id":"https://openalex.org/C38652104","wikidata":"https://www.wikidata.org/wiki/Q3510521","display_name":"Computer security","level":1,"score":0.09272977709770203},{"id":"https://openalex.org/C199539241","wikidata":"https://www.wikidata.org/wiki/Q7748","display_name":"Law","level":1,"score":0.0},{"id":"https://openalex.org/C36289849","wikidata":"https://www.wikidata.org/wiki/Q34749","display_name":"Social science","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.3390/microorganisms7040104","doi":"https://doi.org/10.3390/microorganisms7040104","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/microorganisms7040104","pdf_url":"https://www.mdpi.com/2076-2607/7/4/104/pdf?version=1555839931","source":{"id":"https://openalex.org/S4210222090","display_name":"Microorganisms","issn_l":"2076-2607","issn":["2076-2607"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microorganisms","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6517882","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6517882","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microorganisms","raw_type":"Text"},{"id":"pmid:30979072","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30979072","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microorganisms","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:707ff061a3fb4ffbaea25f00626cd0ae","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/707ff061a3fb4ffbaea25f00626cd0ae","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Microorganisms, Vol 7, Iss 4, p 104 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/microorganisms7040104","doi":"https://doi.org/10.3390/microorganisms7040104","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/microorganisms7040104","pdf_url":"https://www.mdpi.com/2076-2607/7/4/104/pdf?version=1555839931","source":{"id":"https://openalex.org/S4210222090","display_name":"Microorganisms","issn_l":"2076-2607","issn":["2076-2607"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-40","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microorganisms","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2937795185.pdf","grobid_xml":"https://content.openalex.org/works/W2937795185.grobid-xml"},"referenced_works_count":210,"referenced_works":["https://openalex.org/W102167982","https://openalex.org/W184976657","https://openalex.org/W987991538","https://openalex.org/W1491526366","https://openalex.org/W1502081788","https://openalex.org/W1530570582","https://openalex.org/W1533592790","https://openalex.org/W1535341242","https://openalex.org/W1557899177","https://openalex.org/W1560134422","https://openalex.org/W1575597201","https://openalex.org/W1606088617","https://openalex.org/W1715022279","https://openalex.org/W1900292540","https://openalex.org/W1913619429","https://openalex.org/W1941151067","https://openalex.org/W1966541668","https://openalex.org/W1967663492","https://openalex.org/W1972969770","https://openalex.org/W1975038056","https://openalex.org/W1975601232","https://openalex.org/W1981761407","https://openalex.org/W1982307880","https://openalex.org/W1983987206","https://openalex.org/W1985910214","https://openalex.org/W1990681722","https://openalex.org/W1991498982","https://openalex.org/W1993460090","https://openalex.org/W1995465012","https://openalex.org/W1995479108","https://openalex.org/W1998788374","https://openalex.org/W2002527867","https://openalex.org/W2005562606","https://openalex.org/W2006995996","https://openalex.org/W2011683757","https://openalex.org/W2013042266","https://openalex.org/W2018743069","https://openalex.org/W2019795434","https://openalex.org/W2026092764","https://openalex.org/W2027617880","https://openalex.org/W2028557170","https://openalex.org/W2035123430","https://openalex.org/W2038031855","https://openalex.org/W2045664599","https://openalex.org/W2051949131","https://openalex.org/W2056342419","https://openalex.org/W2061065662","https://openalex.org/W2062748749","https://openalex.org/W2066443315","https://openalex.org/W2066973480","https://openalex.org/W2067635988","https://openalex.org/W2073011176","https://openalex.org/W2075624961","https://openalex.org/W2077759571","https://openalex.org/W2082849546","https://openalex.org/W2085159036","https://openalex.org/W2085841195","https://openalex.org/W2091588484","https://openalex.org/W2092825833","https://openalex.org/W2094440904","https://openalex.org/W2096403416","https://openalex.org/W2101281033","https://openalex.org/W2103035669","https://openalex.org/W2105914104","https://openalex.org/W2107141656","https://openalex.org/W2114052438","https://openalex.org/W2114151609","https://openalex.org/W2116431343","https://openalex.org/W2117438470","https://openalex.org/W2118151012","https://openalex.org/W2118721597","https://openalex.org/W2118928270","https://openalex.org/W2120251801","https://openalex.org/W2120452602","https://openalex.org/W2130986448","https://openalex.org/W2132100976","https://openalex.org/W2133352040","https://openalex.org/W2140499820","https://openalex.org/W2146905776","https://openalex.org/W2148535341","https://openalex.org/W2150418225","https://openalex.org/W2152382096","https://openalex.org/W2152811020","https://openalex.org/W2153237448","https://openalex.org/W2156668354","https://openalex.org/W2161688885","https://openalex.org/W2162809090","https://openalex.org/W2163619058","https://openalex.org/W2167402870","https://openalex.org/W2172055614","https://openalex.org/W2184234897","https://openalex.org/W2222629665","https://openalex.org/W2236941093","https://openalex.org/W2268632680","https://openalex.org/W2271716517","https://openalex.org/W2299828058","https://openalex.org/W2343150225","https://openalex.org/W2408320017","https://openalex.org/W2415115978","https://openalex.org/W2422094309","https://openalex.org/W2460748998","https://openalex.org/W2467671738","https://openalex.org/W2468832013","https://openalex.org/W2511309421","https://openalex.org/W2511966849","https://openalex.org/W2522245205","https://openalex.org/W2527237309","https://openalex.org/W2550050547","https://openalex.org/W2561798477","https://openalex.org/W2562334998","https://openalex.org/W2565379187","https://openalex.org/W2570358596","https://openalex.org/W2579373143","https://openalex.org/W2581252295","https://openalex.org/W2586354031","https://openalex.org/W2589562408","https://openalex.org/W2599872458","https://openalex.org/W2602832761","https://openalex.org/W2607230696","https://openalex.org/W2608502548","https://openalex.org/W2613069742","https://openalex.org/W2616265506","https://openalex.org/W2617203645","https://openalex.org/W2620365884","https://openalex.org/W2625298761","https://openalex.org/W2642229481","https://openalex.org/W2734706955","https://openalex.org/W2737581447","https://openalex.org/W2746947791","https://openalex.org/W2755565506","https://openalex.org/W2763617693","https://openalex.org/W2764295308","https://openalex.org/W2765626350","https://openalex.org/W2768971980","https://openalex.org/W2769192423","https://openalex.org/W2770789854","https://openalex.org/W2781848730","https://openalex.org/W2784311706","https://openalex.org/W2788164399","https://openalex.org/W2789526819","https://openalex.org/W2789849801","https://openalex.org/W2790432007","https://openalex.org/W2790625311","https://openalex.org/W2790747618","https://openalex.org/W2792272382","https://openalex.org/W2794440597","https://openalex.org/W2795025463","https://openalex.org/W2796196448","https://openalex.org/W2797170123","https://openalex.org/W2801236945","https://openalex.org/W2802421303","https://openalex.org/W2803009934","https://openalex.org/W2803768443","https://openalex.org/W2804288723","https://openalex.org/W2804603614","https://openalex.org/W2805304181","https://openalex.org/W2807974989","https://openalex.org/W2807991894","https://openalex.org/W2808117464","https://openalex.org/W2809017655","https://openalex.org/W2809387633","https://openalex.org/W2854777997","https://openalex.org/W2859722641","https://openalex.org/W2876964947","https://openalex.org/W2883246981","https://openalex.org/W2883493538","https://openalex.org/W2883791656","https://openalex.org/W2883808454","https://openalex.org/W2883894512","https://openalex.org/W2884412003","https://openalex.org/W2884726817","https://openalex.org/W2885338793","https://openalex.org/W2885492105","https://openalex.org/W2886582157","https://openalex.org/W2888331922","https://openalex.org/W2888543151","https://openalex.org/W2889330136","https://openalex.org/W2889627812","https://openalex.org/W2889758236","https://openalex.org/W2889977344","https://openalex.org/W2890224237","https://openalex.org/W2891057921","https://openalex.org/W2891135984","https://openalex.org/W2892585009","https://openalex.org/W2893639941","https://openalex.org/W2894006377","https://openalex.org/W2894498408","https://openalex.org/W2895640518","https://openalex.org/W2896028828","https://openalex.org/W2896496282","https://openalex.org/W2897456534","https://openalex.org/W2897679920","https://openalex.org/W2897713338","https://openalex.org/W2897732745","https://openalex.org/W2897831266","https://openalex.org/W2898244117","https://openalex.org/W2898810625","https://openalex.org/W2899182140","https://openalex.org/W2900352306","https://openalex.org/W2901195177","https://openalex.org/W2903546985","https://openalex.org/W2904658126","https://openalex.org/W2907020492","https://openalex.org/W2908845694","https://openalex.org/W2921055236","https://openalex.org/W2942641504","https://openalex.org/W3048464890","https://openalex.org/W4210498721","https://openalex.org/W4285719527","https://openalex.org/W6760754092"],"related_works":["https://openalex.org/W2943320595","https://openalex.org/W7130931644","https://openalex.org/W2216350022","https://openalex.org/W2117897418","https://openalex.org/W2168649537","https://openalex.org/W7097423958","https://openalex.org/W3113109983","https://openalex.org/W2027617880","https://openalex.org/W2160891295","https://openalex.org/W2248987205"],"abstract_inverted_index":{"Probiotics":[0],"per":[1],"definition":[2],"should":[3],"have":[4],"beneficial":[5,31,151],"effects":[6,48],"on":[7,45],"human":[8,119],"health,":[9],"and":[10,27,40,49,72,81,148],"their":[11,30,46,146,150],"consumption":[12,122],"has":[13],"tremendously":[14],"increased":[15],"in":[16,61,86,109],"the":[17,22,55,59,77,82,87,91,102,110,118,124,138],"last":[18],"decades.":[19],"In":[20],"parallel,":[21],"amount":[23],"of":[24,58,63,70,84,117,123],"published":[25],"material":[26],"claims":[28],"for":[29],"efficacy":[32,142,147],"soared":[33],"continuously.":[34],"Recently,":[35],"multiple":[36],"systemic":[37],"reviews,":[38],"meta-analyses,":[39],"expert":[41],"opinions":[42],"expressed":[43],"criticism":[44],"claimed":[47],"safety.":[50,74],"The":[51,107],"present":[52],"review":[53],"describes":[54],"dark":[56],"side":[57],"probiotics,":[60],"terms":[62],"problematic":[64],"research":[65],"design,":[66],"incomplete":[67],"reporting,":[68],"lack":[69],"transparency,":[71],"under-reported":[73],"Highlighted":[75],"are":[76,98],"potential":[78],"virulent":[79],"factors":[80],"mode":[83],"action":[85],"intestinal":[88],"lumen,":[89],"risking":[90],"physiological":[92],"microbiome":[93],"equilibrium.":[94],"Finally,":[95],"regulatory":[96],"topics":[97],"discussed":[99],"to":[100],"lighten":[101],"heterogeneous":[103],"guidelines":[104],"applied":[105],"worldwide.":[106],"shift":[108],"scientific":[111],"world":[112],"towards":[113],"a":[114],"better":[115,134],"understanding":[116],"microbiome,":[120],"before":[121],"probiotic":[125,139],"cargo,":[126],"is":[127,131],"highly":[128],"endorsed.":[129],"It":[130],"hoped":[132],"that":[133],"knowledge":[135],"will":[136],"extend":[137],"repertoire,":[140],"re-confirm":[141],"or":[143],"safety,":[144],"establish":[145],"substantiate":[149],"effects.":[152]},"counts_by_year":[{"year":2026,"cited_by_count":15},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":16},{"year":2023,"cited_by_count":17},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":20},{"year":2020,"cited_by_count":16},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":5}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2019-04-25T00:00:00"}
