{"id":"https://openalex.org/W2937579463","doi":"https://doi.org/10.1016/s0618-8278(19)30456-6","title":"THU-181-Safety and efficacy of glecaprevir/pibrentasvir for the treatment of HCV genotype 1-6: Results of the HCV-TARGET study","display_name":"THU-181-Safety and efficacy of glecaprevir/pibrentasvir for the treatment of HCV genotype 1-6: Results of the HCV-TARGET study","publication_year":2019,"publication_date":"2019-04-01","ids":{"openalex":"https://openalex.org/W2937579463","doi":"https://doi.org/10.1016/s0618-8278(19)30456-6","mag":"2937579463"},"language":"en","primary_location":{"id":"doi:10.1016/s0618-8278(19)30456-6","doi":"https://doi.org/10.1016/s0618-8278(19)30456-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0618-8278(19)30456-6","pdf_url":null,"source":{"id":"https://openalex.org/S83651209","display_name":"Journal of Hepatology","issn_l":"0168-8278","issn":["0168-8278","1600-0641"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hepatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085461623","display_name":"Richard K. Sterling","orcid":"https://orcid.org/0000-0002-8637-2475","observed_orcids":["https://orcid.org/0000-0002-8637-2475"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Richard Sterling","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045504446","display_name":"Stefan Zeuzem","orcid":"https://orcid.org/0000-0002-0845-6833","observed_orcids":["https://orcid.org/0000-0002-0845-6833"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stefan Zeuzem","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076572995","display_name":"Tania Mara Welzel","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Tania Welzel","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002183557","display_name":"Michael Peter Manns","orcid":"https://orcid.org/0000-0002-4485-8856","observed_orcids":["https://orcid.org/0000-0002-4485-8856"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael P. Manns","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039066540","display_name":"K. Rajender Reddy","orcid":"https://orcid.org/0000-0002-4898-7778","observed_orcids":["https://orcid.org/0000-0002-4898-7778"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Rajender Reddy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019470247","display_name":"Norah A. Terrault","orcid":"https://orcid.org/0000-0003-4143-1950","observed_orcids":["https://orcid.org/0000-0003-4143-1950"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Norah Terrault","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073481880","display_name":"Ziv Ben\u2010Ari","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ziv Ben Ari","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016897840","display_name":"Irine Vodkin","orcid":"https://orcid.org/0009-0003-2840-551X","observed_orcids":["https://orcid.org/0009-0003-2840-551X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Irine Vodkin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076162712","display_name":"Arifa Toor","orcid":"https://orcid.org/0000-0001-8613-1463","observed_orcids":["https://orcid.org/0000-0001-8613-1463"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Arifa Toor","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056477559","display_name":"Monika Vainorius","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Monika Vainorius","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040164008","display_name":"Lucy Akushevich","orcid":"https://orcid.org/0000-0002-3922-5579","observed_orcids":["https://orcid.org/0000-0002-3922-5579"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lucy Akushevich","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Michael W. Fried","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael W. Fried","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074779832","display_name":"David R. Nelson","orcid":"https://orcid.org/0000-0001-6344-8548","observed_orcids":["https://orcid.org/0000-0001-6344-8548"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David R. Nelson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5053765952","display_name":"Sulkowski Mark","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mark Sulkowski","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.1403,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.47911975,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"70","issue":"1","first_page":"e241","last_page":"e242"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11495","display_name":"Animal Virus Infections Studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10276","display_name":"Helicobacter pylori-related gastroenterology studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/glecaprevir-pibrentasvir","display_name":"glecaprevir/pibrentasvir","score":1.0},{"id":"https://openalex.org/keywords/hepatitis-c-virus","display_name":"hepatitis C virus","score":0.8519999980926514},{"id":"https://openalex.org/keywords/hcv-genotype-1-6","display_name":"HCV genotype 1-6","score":0.9480000138282776},{"id":"https://openalex.org/keywords/direct-acting-antivirals","display_name":"direct-acting antivirals","score":0.890999972820282},{"id":"https://openalex.org/keywords/treatment-safety","display_name":"treatment safety","score":0.7839999794960022},{"id":"https://openalex.org/keywords/treatment-efficacy","display_name":"treatment efficacy","score":0.9459999799728394}],"concepts":[{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.705269455909729},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6253138780593872},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.13979142904281616},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.07302108407020569},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.02759590744972229}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/s0618-8278(19)30456-6","doi":"https://doi.org/10.1016/s0618-8278(19)30456-6","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0618-8278(19)30456-6","pdf_url":null,"source":{"id":"https://openalex.org/S83651209","display_name":"Journal of Hepatology","issn_l":"0168-8278","issn":["0168-8278","1600-0641"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Hepatology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2938022384","https://openalex.org/W2613184552","https://openalex.org/W2940220417","https://openalex.org/W2944321461","https://openalex.org/W2613043977","https://openalex.org/W2613433007","https://openalex.org/W2614089632","https://openalex.org/W2613176236","https://openalex.org/W2799632550","https://openalex.org/W2803093525"],"abstract_inverted_index":null,"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-14T16:39:01.820549","created_date":"2019-04-25T00:00:00"}