{"id":"https://openalex.org/W2936783249","doi":"https://doi.org/10.1200/jco.2015.33.15_suppl.8566","title":"Outcome comparison of allogeneic vs. autologous stem cell transplantation in transformed low grade lymphoid malignancies: A meta-analysis of comparative studies.","display_name":"Outcome comparison of allogeneic vs. autologous stem cell transplantation in transformed low grade lymphoid malignancies: A meta-analysis of comparative studies.","publication_year":2015,"publication_date":"2015-05-20","ids":{"openalex":"https://openalex.org/W2936783249","doi":"https://doi.org/10.1200/jco.2015.33.15_suppl.8566","mag":"2936783249"},"language":"en","primary_location":{"id":"doi:10.1200/jco.2015.33.15_suppl.8566","doi":"https://doi.org/10.1200/jco.2015.33.15_suppl.8566","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2015.33.15_suppl.8566","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011096418","display_name":"Seongseok Yun","orcid":"https://orcid.org/0000-0001-7343-1635","observed_orcids":["https://orcid.org/0000-0001-7343-1635"]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Seongseok Yun","raw_affiliation_strings":["University of Arizona, Tucson, AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Arizona, Tucson, AZ","institution_ids":["https://openalex.org/I138006243"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037828741","display_name":"Nicole D. Vincelette","orcid":"https://orcid.org/0000-0001-7627-6781","observed_orcids":["https://orcid.org/0000-0001-7627-6781"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Nicole Vincelette","raw_affiliation_strings":["Mayo Clinic, Rochseter, MN"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Mayo Clinic, Rochseter, MN","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5040917850","display_name":"Jennifer Margaret Segar","orcid":"https://orcid.org/0000-0002-6345-2093","observed_orcids":["https://orcid.org/0000-0002-6345-2093"]},"institutions":[{"id":"https://openalex.org/I138006243","display_name":"University of Arizona","ror":"https://ror.org/03m2x1q45","country_code":"US","type":"education","lineage":["https://openalex.org/I138006243"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer Segar","raw_affiliation_strings":["University of Arizona, Tucson, AZ"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Arizona, Tucson, AZ","institution_ids":["https://openalex.org/I138006243"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.04936015,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"33","issue":"15_suppl","first_page":"8566","last_page":"8566"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.8525000214576721,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.8525000214576721,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":0.11789999902248383,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research","score":0.01080000028014183,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/allogeneic-stem-cell-transplantation","display_name":"allogeneic stem cell transplantation","score":0.984000027179718},{"id":"https://openalex.org/keywords/autologous-stem-cell-transplantation","display_name":"autologous stem cell transplantation","score":1.0},{"id":"https://openalex.org/keywords/follicular-lymphoma","display_name":"follicular lymphoma","score":0.9919999837875366},{"id":"https://openalex.org/keywords/chronic-lymphocytic-lymphoma","display_name":"chronic lymphocytic lymphoma","score":0.9789999723434448},{"id":"https://openalex.org/keywords/small-lymphocytic-lymphoma","display_name":"small lymphocytic lymphoma","score":0.9959999918937683},{"id":"https://openalex.org/keywords/marginal-zone-lymphoma","display_name":"marginal zone lymphoma","score":1.0},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9150000214576721},{"id":"https://openalex.org/keywords/relapse-rate","display_name":"relapse rate","score":0.746999979019165},{"id":"https://openalex.org/keywords/treatment-related-mortality","display_name":"non-relapse mortality","score":0.9480000138282776},{"id":"https://openalex.org/keywords/rituximab","display_name":"rituximab","score":0.8880000114440918},{"id":"https://openalex.org/keywords/reduced-intensity-conditioning","display_name":"reduced-intensity conditioning","score":0.9909999966621399}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9407036900520325},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6363096237182617},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.6063425540924072},{"id":"https://openalex.org/C2780653079","wikidata":"https://www.wikidata.org/wiki/Q412323","display_name":"Rituximab","level":3,"score":0.5823425650596619},{"id":"https://openalex.org/C2777058707","wikidata":"https://www.wikidata.org/wiki/Q123251","display_name":"Follicular lymphoma","level":3,"score":0.49528732895851135},{"id":"https://openalex.org/C2779338263","wikidata":"https://www.wikidata.org/wiki/Q208414","display_name":"Lymphoma","level":2,"score":0.48765623569488525},{"id":"https://openalex.org/C2779050716","wikidata":"https://www.wikidata.org/wiki/Q4826373","display_name":"Autologous stem-cell transplantation","level":3,"score":0.47737714648246765},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4517577886581421},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.38908058404922485},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.37381711602211}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1200/jco.2015.33.15_suppl.8566","doi":"https://doi.org/10.1200/jco.2015.33.15_suppl.8566","is_oa":false,"landing_page_url":"https://doi.org/10.1200/jco.2015.33.15_suppl.8566","pdf_url":null,"source":{"id":"https://openalex.org/S15137598","display_name":"Journal of Clinical Oncology","issn_l":"0732-183X","issn":["0732-183X","1527-7755"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Clinical Oncology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/systematic-review","display_name":"Systematic Review"},{"id":"https://openalex.org/study-designs/meta-analysis","display_name":"Meta-Analysis"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2547225201","https://openalex.org/W1805061152","https://openalex.org/W2588373691","https://openalex.org/W2588333435","https://openalex.org/W2150748222","https://openalex.org/W2075831092","https://openalex.org/W3111940033","https://openalex.org/W2151694080","https://openalex.org/W2041116601","https://openalex.org/W2946807006"],"abstract_inverted_index":{"8566":[0],"Background:":[1],"Low":[2],"grade":[3,84,109,247],"lymphoid":[4,85,110,248],"malignancy":[5],"is":[6,51],"incurable":[7],"disease":[8,13],"with":[9,53,62,81,107,244],"a":[10,68,151,219],"chronic":[11,116],"relapsing":[12],"course,":[14],"requiring":[15],"recurrent":[16],"therapeutic":[17,240],"interventions.":[18],"Stem":[19],"cell":[20],"transplantation":[21],"(SCT)":[22],"has":[23],"become":[24],"the":[25,28,71,148,159,238],"cornerstone":[26],"in":[27,79,104,158,242],"cure":[29],"of":[30,70,74,99,153,251],"this":[31],"disease.":[32],"While":[33],"both":[34],"allogeneic":[35,49,75,100,165,210],"and":[36,59,93,124,132,150,167,197,211],"autologous":[37,60,77,102,169,212],"SCTs":[38],"have":[39,229],"been":[40],"shown":[41],"to":[42,46,225],"improve":[43],"survival":[44,172],"compared":[45],"conventional":[47],"chemotherapy,":[48],"SCT":[50,61,78,103,166,226,235,257],"associated":[52],"higher":[54,63],"treatment":[55,217,254],"related":[56],"mortality":[57],"(TRM)":[58],"post-transplantation":[64],"relapse.":[65],"We":[66,88],"report":[67],"meta-analysis":[69],"clinical":[72],"outcomes":[73],"vs.":[76,101,176,188,200],"patients":[80,106,155,243],"transformed":[82,245],"low":[83,108,246],"malignancies.":[86],"Methods:":[87],"searched":[89],"PubMed,":[90],"MEDLINE,":[91],"EMBASE":[92],"Cochrane":[94],"databases":[95],"for":[96,147,209],"comparative":[97,143],"studies":[98,144],"adult":[105],"malignancies":[111,249],"including":[112],"follicular":[113],"lymphoma":[114,118,122,127],"(FL),":[115],"lymphocytic":[117,121],"(CLL),":[119],"small":[120],"(SLL)":[123],"marginal":[125],"zone":[126],"(MZL).":[128],"Relative":[129],"risks":[130],"(RR)":[131],"95%":[133,180,192,204],"CI":[134,181,193,205],"were":[135,145,156],"calculated":[136],"using":[137],"random":[138],"effects":[139],"models.":[140],"Results:":[141],"Four":[142],"retained":[146],"meta-analysis,":[149],"total":[152],"526":[154],"included":[157],"analysis.":[160],"Of":[161],"these,":[162],"124":[163],"underwent":[164],"402":[168],"SCT.":[170],"Overall":[171],"(OS)":[173],"was":[174],"50.0%":[175],"66.4%":[177],"(RR":[178,190,202],"1.47,":[179],"1.17-1.84,":[182],"p=":[183,195],"0.001),":[184],"relapse":[185],"rate":[186],"37.3%":[187],"35.3%":[189],"1.04,":[191],"0.70-1.55,":[194],"0.84),":[196],"TRM":[198],"31.5%":[199],"6.7%":[201],"4.53,":[203],"2.89-7.09,":[206],"p<":[207],"0.00001)":[208],"SCT,":[213],"respectively.":[214],"Previous":[215],"rituximab":[216,253],"or":[218,255],"reduced":[220],"intensity":[221],"conditioning":[222,258],"regimen":[223],"prior":[224,256],"did":[227],"not":[228],"independent":[230],"prognostic":[231],"impact.":[232],"Conclusions:":[233],"Autologous":[234],"may":[236],"be":[237],"better":[239],"option":[241],"regardless":[250],"previous":[252],"regimens.":[259]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-04-25T00:00:00"}