{"id":"https://openalex.org/W2935813437","doi":null,"title":"Autobiographical memory and early-onset depression : insights from the environment, genetics and brain structure","display_name":"Autobiographical memory and early-onset depression : insights from the environment, genetics and brain structure","publication_year":2018,"publication_date":"2018-01-01","ids":{"openalex":"https://openalex.org/W2935813437","mag":"2935813437"},"language":"en","primary_location":{"id":"pmh:oai:https://orca.cardiff.ac.uk:119558","doi":null,"is_oa":false,"landing_page_url":"https://orca.cardiff.ac.uk/119558/1/2019WarneN%20PhD.pdf","pdf_url":"https://orca.cardiff.ac.uk/119558/1/2019WarneN%20PhD.pdf","source":{"id":"https://openalex.org/S4306401195","display_name":"ORCA Online Research @Cardiff (Cardiff University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79510175","host_organization_name":"Cardiff University","host_organization_lineage":["https://openalex.org/I79510175"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079861500","display_name":"Naomi Warne","orcid":"https://orcid.org/0000-0001-6160-8982","observed_orcids":["https://orcid.org/0000-0001-6160-8982"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Naomi Warne","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0001-6160-8982","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5079861500"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11983","display_name":"Identity, Memory, and Therapy","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/3204","display_name":"Developmental and Educational Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11983","display_name":"Identity, Memory, and Therapy","score":0.9164999723434448,"subfield":{"id":"https://openalex.org/subfields/3204","display_name":"Developmental and Educational Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10918","display_name":"Memory Processes and Influences","score":0.05130000039935112,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.020899999886751175,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/overgeneral-autobiographical-memory","display_name":"overgeneral autobiographical memory","score":0.9850000143051147},{"id":"https://openalex.org/keywords/early-onset-depression","display_name":"early-onset depression","score":0.9990000128746033},{"id":"https://openalex.org/keywords/depressive-symptoms","display_name":"depressive symptoms","score":0.7369999885559082},{"id":"https://openalex.org/keywords/stressful-life-events","display_name":"life events","score":0.9760000109672546},{"id":"https://openalex.org/keywords/white-matter-tracts","display_name":"white matter tracts","score":0.9539999961853027},{"id":"https://openalex.org/keywords/brain-structure","display_name":"brain structure","score":0.7789999842643738},{"id":"https://openalex.org/keywords/risk-mechanisms","display_name":"risk mechanisms","score":0.6790000200271606},{"id":"https://openalex.org/keywords/depression-prevention","display_name":"depression prevention","score":0.3400000035762787}],"concepts":[{"id":"https://openalex.org/C144814538","wikidata":"https://www.wikidata.org/wiki/Q682304","display_name":"Autobiographical memory","level":3,"score":0.7368640899658203},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6283875703811646},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4420751929283142},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.43912553787231445},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.4244089722633362},{"id":"https://openalex.org/C3019858935","wikidata":"https://www.wikidata.org/wiki/Q4340209","display_name":"Depressive symptoms","level":3,"score":0.41912567615509033},{"id":"https://openalex.org/C180747234","wikidata":"https://www.wikidata.org/wiki/Q23373","display_name":"Cognitive psychology","level":1,"score":0.35705921053886414},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.2809651494026184},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.16136246919631958},{"id":"https://openalex.org/C100660578","wikidata":"https://www.wikidata.org/wiki/Q18733","display_name":"Recall","level":2,"score":0.1347557008266449},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:https://orca.cardiff.ac.uk:119558","doi":null,"is_oa":false,"landing_page_url":"https://orca.cardiff.ac.uk/119558/1/2019WarneN%20PhD.pdf","pdf_url":"https://orca.cardiff.ac.uk/119558/1/2019WarneN%20PhD.pdf","source":{"id":"https://openalex.org/S4306401195","display_name":"ORCA Online Research @Cardiff (Cardiff University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I79510175","host_organization_name":"Cardiff University","host_organization_lineage":["https://openalex.org/I79510175"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:2935813437","doi":null,"is_oa":false,"landing_page_url":"http://orca.cf.ac.uk/119558/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9537000060081482,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":47,"referenced_works":["https://openalex.org/W213417050","https://openalex.org/W300093774","https://openalex.org/W1172213197","https://openalex.org/W1532394360","https://openalex.org/W1560535222","https://openalex.org/W1629717188","https://openalex.org/W1906884999","https://openalex.org/W1922424082","https://openalex.org/W1932439806","https://openalex.org/W1964065874","https://openalex.org/W1986290187","https://openalex.org/W1992231139","https://openalex.org/W1997876639","https://openalex.org/W1997971699","https://openalex.org/W2013150278","https://openalex.org/W2013656874","https://openalex.org/W2018076297","https://openalex.org/W2021417407","https://openalex.org/W2023388466","https://openalex.org/W2029487046","https://openalex.org/W2041751128","https://openalex.org/W2044179713","https://openalex.org/W2060044631","https://openalex.org/W2063001897","https://openalex.org/W2066774644","https://openalex.org/W2074503869","https://openalex.org/W2074595394","https://openalex.org/W2074983109","https://openalex.org/W2086284991","https://openalex.org/W2097145605","https://openalex.org/W2117022355","https://openalex.org/W2118160932","https://openalex.org/W2123263006","https://openalex.org/W2131941134","https://openalex.org/W2147391696","https://openalex.org/W2147927529","https://openalex.org/W2151543699","https://openalex.org/W2156184845","https://openalex.org/W2158323535","https://openalex.org/W2164355830","https://openalex.org/W2169683381","https://openalex.org/W2296042795","https://openalex.org/W2530010419","https://openalex.org/W2783186471","https://openalex.org/W2906253013","https://openalex.org/W2907030468","https://openalex.org/W2914765137"],"related_works":["https://openalex.org/W1982195369","https://openalex.org/W2521559227","https://openalex.org/W3005410691","https://openalex.org/W2279102578","https://openalex.org/W1975938209","https://openalex.org/W3156933671","https://openalex.org/W3155492318","https://openalex.org/W2887285363","https://openalex.org/W2527413249","https://openalex.org/W2002744231"],"abstract_inverted_index":{"Difficulty":[0],"remembering":[1],"specific":[2,199],"events":[3,120],"from":[4,289],"the":[5,36,70,139,177,182],"personal":[6],"past,":[7],"known":[8,113,255],"as":[9,25],"overgeneral":[10,23,39,54,76,105,129,146,158,185,219,236,277],"autobiographical":[11],"memory":[12,24,40,55,77,106,130,147,159,186,220,237,249,278],"(AM),":[13],"has":[14],"been":[15],"associated":[16,86,132,162,193],"with":[17,87,133,141,163,194,266],"adult":[18],"depression.":[19,66,79,142,155,168,188,247,285],"However,":[20],"evidence":[21,275,288],"for":[22,29,64,116,167,225,241,254,284],"a":[26,58,108,222,252,281],"risk":[27,59,62,109,114,166,223,256,282],"factor":[28,60,224],"early-onset":[30,65,226,246],"depression":[31,117,195,227,259,272],"is":[32,41,221],"less":[33],"consistent,":[34],"and":[35,72,78,91,122,148,187,243,261],"aetiology":[37],"of":[38,47,211,245,258],"not":[42,137,161,207,251],"well":[43],"understood.":[44],"The":[45,264],"aim":[46],"this":[48,290],"thesis":[49],"was":[50,85,107,131,160,250],"to":[51,82,198,208],"examine":[52],"whether":[53,104,172],"could":[56,179,238,279],"be":[57,239,280],"or":[61],"mechanism":[63,110,253,283],"\\nI":[67],"first":[68],"examined":[69],"cross-sectional":[71,88,292],"longitudinal":[73,298],"relationships":[74],"between":[75,184],"Overgeneral":[80,248],"AM":[81],"negative":[83],"cues":[84],"depressive":[89,92],"symptoms":[90,93],"three":[94],"years":[95],"later,":[96],"thereby":[97],"indicating":[98],"temporal":[99],"precedence.":[100],"I":[101,170],"also":[102],"assessed":[103],"through":[111],"which":[112],"factors":[115,257],"(stressful":[118],"life":[119],"(SLEs)":[121],"genetic":[123,165,262],"risk)":[124],"exert":[125,150],"their":[126],"effects.":[127],"Although":[128],"SLEs,":[134],"it":[135],"did":[136],"mediate":[138],"relationship":[140],"Instead,":[143],"results":[144],"suggested":[145],"SLEs":[149],"independent":[151],"effects":[152],"on":[153],"subsequent":[154],"In":[156],"contrast,":[157],"common":[164],"Finally":[169],"investigated":[171],"white":[173,267],"matter":[174,190,268],"connections":[175],"in":[176,204,271,296],"brain":[178],"help":[180],"explain":[181],"link":[183],"White":[189],"tracts":[191,269],"previously":[192],"were":[196,202,232],"linked":[197],"AMs":[200],"that":[201,218,276],"positive":[203],"content":[205],"but":[206],"other":[209],"measures":[210],"AM.":[212],"\\nIn":[213],"combination,":[214],"these":[215],"finding":[216],"suggest":[217],"although":[228],"observed":[229],"effect":[230],"sizes":[231],"small.":[233],"Thus,":[234],"targeting":[235],"useful":[240],"treatment":[242],"prevention":[244],"(SLEs":[260],"risk).":[263],"association":[265],"involved":[270],"provides":[273],"preliminary":[274,287],"Nevertheless,":[286],"small":[291],"study":[293],"requires":[294],"replication":[295],"larger,":[297],"studies.":[299]},"counts_by_year":[],"updated_date":"2026-09-26T08:19:03.415552","created_date":"2019-04-25T00:00:00"}