{"id":"https://openalex.org/W2934819398","doi":"https://doi.org/10.1634/theoncologist.2018-0784","title":"Circulating Tumor Cells Identify Patients with Super-High-Risk Non-Muscle-Invasive Bladder Cancer: Updated Outcome Analysis of a Prospective Single-Center Trial","display_name":"Circulating Tumor Cells Identify Patients with Super-High-Risk Non-Muscle-Invasive Bladder Cancer: Updated Outcome Analysis of a Prospective Single-Center Trial","publication_year":2019,"publication_date":"2019-04-03","ids":{"openalex":"https://openalex.org/W2934819398","doi":"https://doi.org/10.1634/theoncologist.2018-0784","mag":"2934819398","pmid":"https://pubmed.ncbi.nlm.nih.gov/30944184","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6516110"},"language":"en","primary_location":{"id":"doi:10.1634/theoncologist.2018-0784","doi":"https://doi.org/10.1634/theoncologist.2018-0784","is_oa":false,"landing_page_url":"https://doi.org/10.1634/theoncologist.2018-0784","pdf_url":null,"source":{"id":"https://openalex.org/S15523509","display_name":"The Oncologist","issn_l":"1083-7159","issn":["1083-7159","1549-490X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316295","host_organization_name":"AlphaMed Press","host_organization_lineage":["https://openalex.org/P4310316295"],"host_organization_lineage_names":["AlphaMed Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Oncologist","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6516110","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5083785848","display_name":"Chiara Nicolazzo","orcid":"https://orcid.org/0000-0002-2551-8979","observed_orcids":["https://orcid.org/0000-0002-2551-8979"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Chiara Nicolazzo","raw_affiliation_strings":["Dipartimento Medicina Molecolare, Sapienza Universit\u00e0 di Roma, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Medicina Molecolare, Sapienza Universit\u00e0 di Roma, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048712745","display_name":"Gian Maria Busetto","orcid":"https://orcid.org/0000-0002-7291-0316","observed_orcids":["https://orcid.org/0000-0002-7291-0316"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Gian Maria Busetto","raw_affiliation_strings":["Dipartimento Scienze Ginecologico-Ostetriche e Scienze Urologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Scienze Ginecologico-Ostetriche e Scienze Urologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5073260221","display_name":"Angela Gradilone","orcid":"https://orcid.org/0000-0002-6007-244X","observed_orcids":["https://orcid.org/0000-0002-6007-244X"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Angela Gradilone","raw_affiliation_strings":["Dipartimento Medicina Molecolare, Sapienza Universit\u00e0 di Roma, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Medicina Molecolare, Sapienza Universit\u00e0 di Roma, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068721926","display_name":"Isabella Sperduti","orcid":"https://orcid.org/0000-0001-5115-3099","observed_orcids":["https://orcid.org/0000-0001-5115-3099"]},"institutions":[{"id":"https://openalex.org/I4387152244","display_name":"Instituto Nazionale Tumori Regina Elena","ror":"https://ror.org/04mgfev69","country_code":"IT","type":"facility","lineage":["https://openalex.org/I4210153126","https://openalex.org/I4387152244"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Isabella Sperduti","raw_affiliation_strings":["IRCCS Istituto Nazionale Tumori Regina Elena, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"IRCCS Istituto Nazionale Tumori Regina Elena, Rome, Italy","institution_ids":["https://openalex.org/I4387152244"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103035067","display_name":"Francesco Del Giudice","orcid":"https://orcid.org/0000-0003-3865-5988","observed_orcids":["https://orcid.org/0000-0003-3865-5988"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Francesco del Giudice","raw_affiliation_strings":["Dipartimento Scienze Ginecologico-Ostetriche e Scienze Urologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Scienze Ginecologico-Ostetriche e Scienze Urologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5022317691","display_name":"Flavia Loreni","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Flavia Loreni","raw_affiliation_strings":["Dipartimento Medicina Molecolare, Sapienza Universit\u00e0 di Roma, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Medicina Molecolare, Sapienza Universit\u00e0 di Roma, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091286114","display_name":"Enrico Cortesi","orcid":"https://orcid.org/0000-0002-8671-0155","observed_orcids":["https://orcid.org/0000-0002-8671-0155"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Enrico Cortesi","raw_affiliation_strings":["Dipartimento Scienze Radiologiche, Oncologiche e Patologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Scienze Radiologiche, Oncologiche e Patologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017259461","display_name":"Ettore DE BERARDINIS","orcid":"https://orcid.org/0000-0003-1498-2810","observed_orcids":["https://orcid.org/0000-0003-1498-2810"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Ettore de Berardinis","raw_affiliation_strings":["Dipartimento Scienze Ginecologico-Ostetriche e Scienze Urologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Scienze Ginecologico-Ostetriche e Scienze Urologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024241976","display_name":"Paola Gazzaniga","orcid":"https://orcid.org/0000-0002-2325-2273","observed_orcids":["https://orcid.org/0000-0002-2325-2273"]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Paola Gazzaniga","raw_affiliation_strings":["Dipartimento Medicina Molecolare, Sapienza Universit\u00e0 di Roma, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Medicina Molecolare, Sapienza Universit\u00e0 di Roma, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012791603","display_name":"Cristina Raimondi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"Cristina Raimondi","raw_affiliation_strings":["Dipartimento Scienze Radiologiche, Oncologiche e Patologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dipartimento Scienze Radiologiche, Oncologiche e Patologiche, Sapienza Universit\u00e0 di Roma, Rome, Italy","institution_ids":["https://openalex.org/I861853513"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5012791603"],"corresponding_institution_ids":["https://openalex.org/I861853513"],"apc_list":{"value":1450,"currency":"USD","value_usd":1450},"apc_paid":null,"fwci":8.488,"has_fulltext":true,"cited_by_count":51,"citation_normalized_percentile":{"value":0.98439631,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":100},"biblio":{"volume":"24","issue":"5","first_page":"612","last_page":"616"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10458","display_name":"Bladder and Urothelial Cancer Treatments","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12695","display_name":"Urinary and Genital Oncology Studies","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/circulating-tumor-cells","display_name":"circulating tumor cells","score":0.9710000157356262},{"id":"https://openalex.org/keywords/non-muscle-invasive-bladder-cancer","display_name":"non-muscle-invasive bladder cancer","score":0.9929999709129333},{"id":"https://openalex.org/keywords/high-grade-t1-bladder-cancer","display_name":"high-grade T1 bladder cancer","score":0.9819999933242798},{"id":"https://openalex.org/keywords/cancer-specific-survival","display_name":"cancer-specific survival","score":0.75},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.9860000014305115},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9810000061988831},{"id":"https://openalex.org/keywords/liquid-biopsy","display_name":"liquid biopsy","score":0.8410000205039978},{"id":"https://openalex.org/keywords/risk-stratification","display_name":"risk stratification","score":0.8970000147819519},{"id":"https://openalex.org/keywords/recurrence","display_name":"recurrence","score":0.578000009059906},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.75},{"id":"https://openalex.org/keywords/surveillance-strategy","display_name":"surveillance strategy","score":0.5820000171661377}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9376451373100281},{"id":"https://openalex.org/C2780352672","wikidata":"https://www.wikidata.org/wiki/Q504775","display_name":"Bladder cancer","level":3,"score":0.8788983821868896},{"id":"https://openalex.org/C34626388","wikidata":"https://www.wikidata.org/wiki/Q721129","display_name":"Nomogram","level":2,"score":0.7362799048423767},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6050233244895935},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.5913715958595276},{"id":"https://openalex.org/C188816634","wikidata":"https://www.wikidata.org/wiki/Q2113324","display_name":"Prospective cohort study","level":2,"score":0.5464110374450684},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5088715553283691},{"id":"https://openalex.org/C61238886","wikidata":"https://www.wikidata.org/wiki/Q5121689","display_name":"Circulating tumor cell","level":4,"score":0.49810171127319336},{"id":"https://openalex.org/C2780073493","wikidata":"https://www.wikidata.org/wiki/Q7523837","display_name":"Single Center","level":2,"score":0.41015490889549255},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.36240535974502563},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.09607928991317749}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D001749","descriptor_name":"Urinary Bladder Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009360","descriptor_name":"Neoplastic Cells, Circulating","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009360","descriptor_name":"Neoplastic Cells, Circulating","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011446","descriptor_name":"Prospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1634/theoncologist.2018-0784","doi":"https://doi.org/10.1634/theoncologist.2018-0784","is_oa":false,"landing_page_url":"https://doi.org/10.1634/theoncologist.2018-0784","pdf_url":null,"source":{"id":"https://openalex.org/S15523509","display_name":"The Oncologist","issn_l":"1083-7159","issn":["1083-7159","1549-490X"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310316295","host_organization_name":"AlphaMed Press","host_organization_lineage":["https://openalex.org/P4310316295"],"host_organization_lineage_names":["AlphaMed Press"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Oncologist","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:6004130","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6516110","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:30944184","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30944184","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The oncologist","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6516110","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6516110/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Oncologist","raw_type":"Text"},{"id":"pmh:oai:iris.uniroma1.it:11573/1259469","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11573/1259469","pdf_url":"http://hdl.handle.net/11573/1259469","source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:6004130","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6516110","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2934819398.pdf","grobid_xml":"https://content.openalex.org/works/W2934819398.grobid-xml"},"referenced_works_count":14,"referenced_works":["https://openalex.org/W420909561","https://openalex.org/W1833411836","https://openalex.org/W2080696159","https://openalex.org/W2130373985","https://openalex.org/W2168428234","https://openalex.org/W2626502646","https://openalex.org/W2741219503","https://openalex.org/W2772091955","https://openalex.org/W2787873669","https://openalex.org/W2791986466","https://openalex.org/W2895985564","https://openalex.org/W2898525679","https://openalex.org/W2898545403","https://openalex.org/W3104970740"],"related_works":["https://openalex.org/W2573606639","https://openalex.org/W2168428234","https://openalex.org/W2153133755","https://openalex.org/W1991480701","https://openalex.org/W4234516268","https://openalex.org/W4409167745","https://openalex.org/W2317521610","https://openalex.org/W2007206006","https://openalex.org/W2058603351","https://openalex.org/W1983972334"],"abstract_inverted_index":{"BACKGROUND:":[0],"Clinical":[1],"behavior":[2],"of":[3,19,35,42,46,54,72,84,87,127,137,159,169,176,189,203,271,276],"non-muscle-invasive":[4,246,259],"bladder":[5,29,67,106,153,247,260],"cancer":[6,30,107,261],"(NMIBC)":[7],"is":[8,31,86,174],"largely":[9],"unpredictable,":[10],"and":[11,44,57,69,100,144,179,199],"even":[12,170,235],"patients":[13,85,104,150,224,243,256,277],"treated":[14],"according":[15],"to":[16,76,91,133],"European":[17],"Association":[18],"Urology":[20],"recommendations":[21],"have":[22,108],"a":[23,128,156,171,236],"heterogeneous":[24],"prognosis.":[25],"High-grade":[26],"T1":[27],"(HGT1)":[28],"the":[32,70,113,124,135,167,184,196,200,219],"highest-risk":[33],"subtype":[34],"NMIBC,":[36],"with":[37,105,151,183,244,257],"an":[38,230],"almost":[39],"40%":[40],"rate":[41],"recurrence":[43,268],"20%":[45],"progression":[47,270],"at":[48],"5":[49],"years.":[50,116],"Nomograms":[51],"predicting":[52],"risk":[53,209],"recurrence,":[55],"progression,":[56],"cancer-specific":[58],"survival":[59,146],"(CSS)":[60],"are":[61,195],"not":[62],"available":[63],"specifically":[64],"within":[65],"HGT1":[66,152],"cancer,":[68,154],"identification":[71],"robust":[73],"prognostic":[74],"biomarkers":[75,94],"better":[77],"guide":[78],"therapeutic":[79],"strategies":[80],"in":[81,95,112,148,155,191,242,289],"this":[82,192],"subgroup":[83,275],"paramount":[88],"importance.":[89],"Strategies":[90],"identify":[92,255],"putative":[93],"liquid":[96],"biopsies":[97],"from":[98,103],"blood":[99],"urine":[101],"collected":[102],"been":[109],"intensively":[110],"studied":[111],"last":[114],"few":[115],"SUBJECTS,":[117],"MATERIALS,":[118],"AND":[119],"METHODS:":[120],"We":[121,163],"here":[122,164],"report":[123],"final":[125],"analysis":[126,194],"single-center":[129],"prospective":[130,291],"study":[131],"aimed":[132],"investigate":[134],"impact":[136],"circulating":[138],"tumor":[139,253],"cells":[140,254],"(CTCs)":[141],"on":[142],"CSS":[143,178],"overall":[145],"(OS)":[147],"102":[149],"median":[157],"follow-up":[158,198],"63":[160],"months.":[161],"RESULTS:":[162],"demonstrate":[165],"that":[166],"presence":[168],"single":[172],"CTC":[173],"predictive":[175,186],"shorter":[177],"OS,":[180],"as":[181],"compared":[182],"standard":[185],"variables.":[187],"Points":[188],"attention":[190],"multivariable":[193],"long-term":[197],"adequate":[201],"number":[202],"outcome":[204],"events.":[205],"CONCLUSION:":[206],"The":[207],"accurate":[208],"stratification":[210],"provided":[211],"by":[212],"CTCs":[213],"might":[214,239,278],"be":[215,240,287],"essential":[216],"for":[217,223,266],"determining":[218],"best":[220],"surveillance":[221],"strategy":[222],"after":[225],"diagnosis.":[226],"A":[227],"closer":[228,264],"follow-up,":[229],"early":[231],"radical":[232],"surgery,":[233],"or":[234],"systemic":[237],"treatment":[238,283],"recommended":[241],"super-high-risk":[245,258,274],"cancer.":[248],"IMPLICATIONS":[249],"FOR":[250],"PRACTICE:":[251],"Circulating":[252],"who":[262],"require":[263,280],"monitoring":[265],"local":[267],"and/or":[269],"disease.":[272],"This":[273],"also":[279],"more":[281],"aggressive":[282],"interventions,":[284],"which":[285],"should":[286],"evaluated":[288],"large":[290],"cohorts.":[292]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":5},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":20},{"year":2020,"cited_by_count":8}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2019-04-11T00:00:00"}