{"id":"https://openalex.org/W2934492880","doi":"https://doi.org/10.1007/s11248-019-00122-9","title":"Transcription termination sequences support the expression of transgene product secreted with milk","display_name":"Transcription termination sequences support the expression of transgene product secreted with milk","publication_year":2019,"publication_date":"2019-03-28","ids":{"openalex":"https://openalex.org/W2934492880","doi":"https://doi.org/10.1007/s11248-019-00122-9","mag":"2934492880","pmid":"https://pubmed.ncbi.nlm.nih.gov/30919251"},"language":"en","primary_location":{"id":"doi:10.1007/s11248-019-00122-9","doi":"https://doi.org/10.1007/s11248-019-00122-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11248-019-00122-9","pdf_url":null,"source":{"id":"https://openalex.org/S190862277","display_name":"Transgenic Research","issn_l":"0962-8819","issn":["0962-8819","1573-9368"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transgenic Research","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5017239196","display_name":"Alexey V. Deykin","orcid":"https://orcid.org/0000-0001-9960-0863","observed_orcids":["https://orcid.org/0000-0001-9960-0863"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210110167","display_name":"Institute of Gene Biology","ror":"https://ror.org/01yq9ya27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110167","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Alexey Deykin","raw_affiliation_strings":["Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012129577","display_name":"M. V. Tikhonov","orcid":"https://orcid.org/0000-0001-7857-8855","observed_orcids":["https://orcid.org/0000-0001-7857-8855"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210110167","display_name":"Institute of Gene Biology","ror":"https://ror.org/01yq9ya27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110167","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Maxim Tikhonov","raw_affiliation_strings":["Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060329563","display_name":"Vladislav A. Kalmykov","orcid":"https://orcid.org/0000-0002-9125-8538","observed_orcids":["https://orcid.org/0000-0002-9125-8538"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210110167","display_name":"Institute of Gene Biology","ror":"https://ror.org/01yq9ya27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110167","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Vladislav Kalmykov","raw_affiliation_strings":["Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103190009","display_name":"Igor V. Korobko","orcid":"https://orcid.org/0000-0001-6406-3471","observed_orcids":["https://orcid.org/0000-0001-6406-3471"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210110167","display_name":"Institute of Gene Biology","ror":"https://ror.org/01yq9ya27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110167","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Igor Korobko","raw_affiliation_strings":["Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057581244","display_name":"Pavel G Georgiev","orcid":"https://orcid.org/0000-0002-6509-3194","observed_orcids":["https://orcid.org/0000-0002-6509-3194"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210110167","display_name":"Institute of Gene Biology","ror":"https://ror.org/01yq9ya27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110167","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Pavel Georgiev","raw_affiliation_strings":["Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334. georgiev_p@mail.ru","Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334. georgiev_p@mail.ru","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"]},{"raw_affiliation_string":"Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5014729529","display_name":"Oksana G Maksimenko","orcid":"https://orcid.org/0000-0003-3502-0303","observed_orcids":["https://orcid.org/0000-0003-3502-0303"]},"institutions":[{"id":"https://openalex.org/I1313323035","display_name":"Russian Academy of Sciences","ror":"https://ror.org/05qrfxd25","country_code":"RU","type":"government","lineage":["https://openalex.org/I1313323035"]},{"id":"https://openalex.org/I4210110167","display_name":"Institute of Gene Biology","ror":"https://ror.org/01yq9ya27","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110167","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":true,"raw_author_name":"Oksana Maksimenko","raw_affiliation_strings":["Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334. maksog@mail.ru","Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334"],"raw_orcid":"https://orcid.org/0000-0003-3502-0303","affiliations":[{"raw_affiliation_string":"Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334. maksog@mail.ru","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"]},{"raw_affiliation_string":"Institute of Gene Biology, Russian Academy of Sciences, 34/5 Vavilova St., Moscow, Russia, 119334","institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5014729529","https://openalex.org/A5057581244"],"corresponding_institution_ids":["https://openalex.org/I1313323035","https://openalex.org/I4210110167"],"apc_list":{"value":3140,"currency":"USD","value_usd":3140},"apc_paid":null,"fwci":0.3827,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.55714516,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"28","issue":"3-4","first_page":"401","last_page":"410"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12929","display_name":"Animal Genetics and Reproduction","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11426","display_name":"Genetically Modified Organisms Research","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcription-termination","display_name":"transcription termination","score":0.7839999794960022},{"id":"https://openalex.org/keywords/transcription-terminator","display_name":"transcription terminator","score":0.5580000281333923},{"id":"https://openalex.org/keywords/chromatin-insulators","display_name":"chromatin insulators","score":0.718999981880188},{"id":"https://openalex.org/keywords/bidirectional-transcription","display_name":"bidirectional transcription","score":0.7689999938011169},{"id":"https://openalex.org/keywords/firefly-luciferase","display_name":"firefly luciferase","score":0.7310000061988831},{"id":"https://openalex.org/keywords/reporter-gene-expression","display_name":"reporter gene expression","score":0.8970000147819519},{"id":"https://openalex.org/keywords/mammary-gland-expression","display_name":"mammary gland expression","score":0.7239999771118164},{"id":"https://openalex.org/keywords/transgene-expression","display_name":"transgene expression","score":0.6449999809265137},{"id":"https://openalex.org/keywords/transgenic-mice","display_name":"transgenic mice","score":0.8479999899864197}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8755947351455688},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.7801789045333862},{"id":"https://openalex.org/C161733203","wikidata":"https://www.wikidata.org/wiki/Q911828","display_name":"Reporter gene","level":4,"score":0.70670086145401},{"id":"https://openalex.org/C83640560","wikidata":"https://www.wikidata.org/wiki/Q180951","display_name":"Chromatin","level":3,"score":0.6417813301086426},{"id":"https://openalex.org/C101762097","wikidata":"https://www.wikidata.org/wiki/Q224093","display_name":"Promoter","level":4,"score":0.6360666155815125},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.6205919981002808},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.6076863408088684},{"id":"https://openalex.org/C111335760","wikidata":"https://www.wikidata.org/wiki/Q95385166","display_name":"Luciferase","level":4,"score":0.5873616933822632},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.5651777982711792},{"id":"https://openalex.org/C165864922","wikidata":"https://www.wikidata.org/wiki/Q411391","display_name":"Regulation of gene expression","level":3,"score":0.48456087708473206},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4525463283061981},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.4219472110271454},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.394015371799469},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.34123149514198303},{"id":"https://openalex.org/C54009773","wikidata":"https://www.wikidata.org/wiki/Q1429031","display_name":"Transfection","level":3,"score":0.12107589840888977},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002364","descriptor_name":"Caseins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D002645","descriptor_name":"Chickens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005822","descriptor_name":"Genetic Vectors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006041","descriptor_name":"Goats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008321","descriptor_name":"Mammary Glands, Animal","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008822","descriptor_name":"Mice, Transgenic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008892","descriptor_name":"Milk","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D019076","descriptor_name":"Transgenes","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019076","descriptor_name":"Transgenes","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D038101","descriptor_name":"Insulator Elements","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049409","descriptor_name":"Luciferases, Firefly","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D049409","descriptor_name":"Luciferases, Firefly","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061806","descriptor_name":"Transcription Termination, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1007/s11248-019-00122-9","doi":"https://doi.org/10.1007/s11248-019-00122-9","is_oa":false,"landing_page_url":"https://doi.org/10.1007/s11248-019-00122-9","pdf_url":null,"source":{"id":"https://openalex.org/S190862277","display_name":"Transgenic Research","issn_l":"0962-8819","issn":["0962-8819","1573-9368"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transgenic Research","raw_type":"journal-article"},{"id":"pmid:30919251","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30919251","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Transgenic research","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G589815786","display_name":null,"funder_award_id":"16-14-00150","funder_id":"https://openalex.org/F4320324099","funder_display_name":"Russian Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320324099","display_name":"Russian Science Foundation","ror":"https://ror.org/03y2gwe85"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":44,"referenced_works":["https://openalex.org/W15974371","https://openalex.org/W79947600","https://openalex.org/W118749991","https://openalex.org/W1496130738","https://openalex.org/W1968306657","https://openalex.org/W1970255649","https://openalex.org/W1979105653","https://openalex.org/W1981411218","https://openalex.org/W2004442869","https://openalex.org/W2005153747","https://openalex.org/W2010413312","https://openalex.org/W2013130016","https://openalex.org/W2021193053","https://openalex.org/W2021309463","https://openalex.org/W2033094967","https://openalex.org/W2034885445","https://openalex.org/W2042447587","https://openalex.org/W2042969349","https://openalex.org/W2045337942","https://openalex.org/W2045389980","https://openalex.org/W2049440966","https://openalex.org/W2050316998","https://openalex.org/W2052370283","https://openalex.org/W2056608604","https://openalex.org/W2059602047","https://openalex.org/W2062875409","https://openalex.org/W2069211652","https://openalex.org/W2105427468","https://openalex.org/W2106554405","https://openalex.org/W2109110632","https://openalex.org/W2112001233","https://openalex.org/W2136725005","https://openalex.org/W2145540744","https://openalex.org/W2146383850","https://openalex.org/W2153222734","https://openalex.org/W2160899662","https://openalex.org/W2185382397","https://openalex.org/W2259826123","https://openalex.org/W2341987872","https://openalex.org/W2416063236","https://openalex.org/W2429520816","https://openalex.org/W2760056442","https://openalex.org/W2890674735","https://openalex.org/W4297819558"],"related_works":["https://openalex.org/W2034348856","https://openalex.org/W2414719331","https://openalex.org/W2131524339","https://openalex.org/W2045389980","https://openalex.org/W2948540067","https://openalex.org/W2021193053","https://openalex.org/W2040876899","https://openalex.org/W4280555058","https://openalex.org/W2761425244","https://openalex.org/W2300365822"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-04-11T00:00:00"}