{"id":"https://openalex.org/W2931946102","doi":"https://doi.org/10.2147/ott.s196851","title":"Differentiation antagonizing non-protein coding RNA modulates the proliferation, migration, and angiogenesis of glioma cells by targeting the miR-216a/LGR5 axis and the PI3K/AKT signaling pathway","display_name":"Differentiation antagonizing non-protein coding RNA modulates the proliferation, migration, and angiogenesis of glioma cells by targeting the miR-216a/LGR5 axis and the PI3K/AKT signaling pathway","publication_year":2019,"publication_date":"2019-04-01","ids":{"openalex":"https://openalex.org/W2931946102","doi":"https://doi.org/10.2147/ott.s196851","mag":"2931946102","pmid":"https://pubmed.ncbi.nlm.nih.gov/31114219","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6497507"},"language":"en","primary_location":{"id":"doi:10.2147/ott.s196851","doi":"https://doi.org/10.2147/ott.s196851","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ott.s196851","pdf_url":"https://www.dovepress.com/getfile.php?fileID=48911","source":{"id":"https://openalex.org/S120324992","display_name":"OncoTargets and Therapy","issn_l":"1178-6930","issn":["1178-6930"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoTargets and Therapy","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.dovepress.com/getfile.php?fileID=48911","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100392203","display_name":"Wei Wang","orcid":"https://orcid.org/0000-0003-1696-9759","observed_orcids":["https://orcid.org/0000-0003-1696-9759"]},"institutions":[{"id":"https://openalex.org/I44673925","display_name":"Inner Mongolia Medical University","ror":"https://ror.org/01mtxmr84","country_code":"CN","type":"funder","lineage":["https://openalex.org/I44673925"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Wang","raw_affiliation_strings":["Department of Medical Oncology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China","institution_ids":["https://openalex.org/I44673925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101984616","display_name":"Yulian Li","orcid":"https://orcid.org/0000-0001-6551-8984","observed_orcids":["https://orcid.org/0000-0001-6551-8984"]},"institutions":[{"id":"https://openalex.org/I44673925","display_name":"Inner Mongolia Medical University","ror":"https://ror.org/01mtxmr84","country_code":"CN","type":"funder","lineage":["https://openalex.org/I44673925"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yulian Li","raw_affiliation_strings":["Department of Pathology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China","institution_ids":["https://openalex.org/I44673925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100930511","display_name":"Qinghai Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44673925","display_name":"Inner Mongolia Medical University","ror":"https://ror.org/01mtxmr84","country_code":"CN","type":"funder","lineage":["https://openalex.org/I44673925"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qinghai Ma","raw_affiliation_strings":["Department of Neurosurgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China","institution_ids":["https://openalex.org/I44673925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014530365","display_name":"Haicheng Yan","orcid":"https://orcid.org/0009-0004-8677-5831","observed_orcids":["https://orcid.org/0009-0004-8677-5831"]},"institutions":[{"id":"https://openalex.org/I44673925","display_name":"Inner Mongolia Medical University","ror":"https://ror.org/01mtxmr84","country_code":"CN","type":"funder","lineage":["https://openalex.org/I44673925"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Haicheng Yan","raw_affiliation_strings":["Department of Neurosurgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neurosurgery, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China","institution_ids":["https://openalex.org/I44673925"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5022329205","display_name":"Wuyun Su","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I44673925","display_name":"Inner Mongolia Medical University","ror":"https://ror.org/01mtxmr84","country_code":"CN","type":"funder","lineage":["https://openalex.org/I44673925"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Wuyun Su","raw_affiliation_strings":["Department of Medical Oncology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medical Oncology, Affiliated Hospital of Inner Mongolia Medical University, Hohhot 010050, People's Republic of China","institution_ids":["https://openalex.org/I44673925"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5014530365","https://openalex.org/A5022329205"],"corresponding_institution_ids":["https://openalex.org/I44673925"],"apc_list":{"value":2836,"currency":"USD","value_usd":2836},"apc_paid":{"value":2836,"currency":"USD","value_usd":2836},"fwci":0.9785,"has_fulltext":true,"cited_by_count":15,"citation_normalized_percentile":{"value":0.67723128,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"Volume 12","issue":null,"first_page":"2439","last_page":"2449"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research","score":0.9463000297546387,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.0471000000834465,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/dancr","display_name":"DANCR","score":0.9890000224113464},{"id":"https://openalex.org/keywords/long-non-coding-rna","display_name":"long non-coding RNA","score":0.8059999942779541},{"id":"https://openalex.org/keywords/glioma","display_name":"glioma","score":0.9739999771118164},{"id":"https://openalex.org/keywords/mir-216a","display_name":"miR-216a","score":0.9990000128746033},{"id":"https://openalex.org/keywords/lgr5","display_name":"Lgr5","score":1.0},{"id":"https://openalex.org/keywords/pi3k-akt-signaling","display_name":"PI3K/Akt signaling","score":0.9679999947547913},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.7639999985694885},{"id":"https://openalex.org/keywords/cell-migration-and-invasion","display_name":"cell migration and invasion","score":0.9440000057220459},{"id":"https://openalex.org/keywords/angiogenesis","display_name":"angiogenesis","score":0.9089999794960022},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9629999995231628},{"id":"https://openalex.org/keywords/g1-s-cell-cycle-arrest","display_name":"G1/S cell cycle arrest","score":0.8980000019073486},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.6330000162124634}],"concepts":[{"id":"https://openalex.org/C86554907","wikidata":"https://www.wikidata.org/wiki/Q285613","display_name":"PI3K/AKT/mTOR pathway","level":3,"score":0.7066552042961121},{"id":"https://openalex.org/C3020116447","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal pathway","level":3,"score":0.7053307294845581},{"id":"https://openalex.org/C75217442","wikidata":"https://www.wikidata.org/wiki/Q423650","display_name":"Protein kinase B","level":3,"score":0.6480549573898315},{"id":"https://openalex.org/C10116572","wikidata":"https://www.wikidata.org/wiki/Q18033097","display_name":"LGR5","level":4,"score":0.6084524989128113},{"id":"https://openalex.org/C2780394083","wikidata":"https://www.wikidata.org/wiki/Q539568","display_name":"Angiogenesis","level":2,"score":0.5829488039016724},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.568320095539093},{"id":"https://openalex.org/C2778227246","wikidata":"https://www.wikidata.org/wiki/Q1365309","display_name":"Glioma","level":2,"score":0.4649805724620819},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.45500844717025757},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.38721704483032227},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.37514162063598633},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35070234537124634},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.30361443758010864},{"id":"https://openalex.org/C137620995","wikidata":"https://www.wikidata.org/wiki/Q155769","display_name":"Wnt signaling pathway","level":3,"score":0.11071315407752991}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.2147/ott.s196851","doi":"https://doi.org/10.2147/ott.s196851","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ott.s196851","pdf_url":"https://www.dovepress.com/getfile.php?fileID=48911","source":{"id":"https://openalex.org/S120324992","display_name":"OncoTargets and Therapy","issn_l":"1178-6930","issn":["1178-6930"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoTargets and Therapy","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5497961","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6497507","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6497507","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6497507","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Onco Targets Ther","raw_type":"Text"},{"id":"pmid:31114219","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31114219","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoTargets and therapy","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:bf3882d981a14575af48b2d7cee87394","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/bf3882d981a14575af48b2d7cee87394","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"OncoTargets and Therapy, Vol Volume 12, Pp 2439-2449 (2019)","raw_type":"article"},{"id":"pmh:oai:dovepress.com/44911","doi":null,"is_oa":true,"landing_page_url":"https://www.dovepress.com/differentiation-antagonizing-non-protein-coding-rna-modulates-the-prol-peer-reviewed-article-OTT","pdf_url":null,"source":{"id":"https://openalex.org/S4306401012","display_name":"Dove Medical Press (Taylor and Francis Group)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.2147/ott.s196851","doi":"https://doi.org/10.2147/ott.s196851","is_oa":true,"landing_page_url":"https://doi.org/10.2147/ott.s196851","pdf_url":"https://www.dovepress.com/getfile.php?fileID=48911","source":{"id":"https://openalex.org/S120324992","display_name":"OncoTargets and Therapy","issn_l":"1178-6930","issn":["1178-6930"],"is_oa":true,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320348","host_organization_name":"Dove Medical Press","host_organization_lineage":["https://openalex.org/P4310320348","https://openalex.org/P4310320547"],"host_organization_lineage_names":["Dove Medical Press","Taylor & Francis"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"OncoTargets and Therapy","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.98580002784729,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1520668279","display_name":"RNA\u5e72\u6270securin\u5bf9\u80f6\u8d28\u7624\u51cb\u4ea1\u3001\u66ff\u83ab\u5511\u80fa\u8010\u836f\u6027\u7684\u5f71\u54cd\u53ca\u673a\u5236\u7814\u7a76","funder_award_id":"81660469","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G5930950275","display_name":null,"funder_award_id":"No. 2016BS0809","funder_id":"https://openalex.org/F4320322868","funder_display_name":"Natural Science Foundation of Inner Mongolia"}],"funders":[{"id":"https://openalex.org/F4320317451","display_name":"Inner Mongolia Medical University","ror":"https://ror.org/01mtxmr84"},{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320322868","display_name":"Natural Science Foundation of Inner Mongolia","ror":null}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2931946102.pdf","grobid_xml":"https://content.openalex.org/works/W2931946102.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1105989094","https://openalex.org/W1121277736","https://openalex.org/W1887150516","https://openalex.org/W1965057786","https://openalex.org/W1978967539","https://openalex.org/W1982603620","https://openalex.org/W1984621921","https://openalex.org/W1989198239","https://openalex.org/W2009364489","https://openalex.org/W2017927877","https://openalex.org/W2047269391","https://openalex.org/W2054661457","https://openalex.org/W2056183265","https://openalex.org/W2074263100","https://openalex.org/W2097387056","https://openalex.org/W2171977041","https://openalex.org/W2593000083","https://openalex.org/W2679876199","https://openalex.org/W2734208961","https://openalex.org/W2735687500","https://openalex.org/W2743216871","https://openalex.org/W2761718018","https://openalex.org/W2766356594","https://openalex.org/W2781525129","https://openalex.org/W2782051230","https://openalex.org/W2789387026","https://openalex.org/W2796270756","https://openalex.org/W2796324480","https://openalex.org/W2801483070","https://openalex.org/W2802819532","https://openalex.org/W2803358834","https://openalex.org/W2808979164","https://openalex.org/W2809410583","https://openalex.org/W2887621676","https://openalex.org/W2892112970","https://openalex.org/W2894640130","https://openalex.org/W2945792041","https://openalex.org/W2987265477","https://openalex.org/W3003719912"],"related_works":["https://openalex.org/W3011096237","https://openalex.org/W2782051230","https://openalex.org/W2796324480","https://openalex.org/W6939383118","https://openalex.org/W2809410583","https://openalex.org/W3094544537","https://openalex.org/W3092739515","https://openalex.org/W2593000083","https://openalex.org/W7165379543","https://openalex.org/W4313544701"],"abstract_inverted_index":{"Purpose:":[0],"DANCR":[1,32,36,62,95,110,148,186,208],"plays":[2],"an":[3],"important":[4],"role":[5,13,30],"in":[6,14,33,100,104,149,200],"various":[7],"types":[8],"of":[9,31,44,59,79,109,117,144,147,167,180,190,194],"cancer.":[10],"However,":[11],"its":[12],"gliomas":[15],"remains":[16],"unclear.":[17],"In":[18,174],"the":[19,26,29,123,127,181,215],"present":[20],"study,":[21],"we":[22],"aimed":[23],"to":[24],"investigate":[25],"mechanism":[27],"underlying":[28],"gliomas.":[34],"Methods:":[35],"expression":[37,43,96],"was":[38,52,63,97],"measured":[39,83],"by":[40,54,65,84,185,213],"qRT-PCR,":[41],"and":[42,48,61,71,75,77,89,115,130,134,162,164,198,211,218],"LGR5,":[45,132,195],"PI3K,":[46,133,196],"AKT,":[47,197],"phosphorylated":[49],"AKT":[50],"(p-AKT)":[51],"detected":[53],"western":[55],"blotting.":[56],"The":[57],"combination":[58],"miR-216a":[60,139,153,156,176,191,228],"quantified":[64],"Luciferase":[66],"reporter":[67],"assays.":[68],"Proliferation,":[69],"apoptosis":[70,166],"cell":[72,124],"cycle,":[73],"migration":[74],"invasion,":[76,114,161,225],"angiogenesis":[78,116,163],"glioma":[80,101,118,150,168,201],"cells":[81,102,151,169,202],"were":[82],"MTT,":[85],"flow":[86],"cytometry,":[87],"Transwell,":[88],"Tube":[90],"formation":[91],"assays,":[92],"respectively.":[93],"Results:":[94],"significantly":[98],"higher":[99],"than":[103],"normal":[105],"human":[106],"astrocytes.":[107],"Silencing":[108,146],"inhibited":[111,165],"proliferation,":[112,159],"migration,":[113,160,224],"cells,":[119],"promoted":[120],"apoptosis,":[121],"blocked":[122],"cycle":[125],"at":[126],"G1/S":[128,182],"transition,":[129],"reduced":[131],"p-AKT":[135,199],"expression.":[136,154],"We":[137],"identified":[138],"as":[140],"a":[141],"direct":[142],"target":[143],"DANCR.":[145],"increased":[152,158,192],"Further,":[155],"suppression":[157,177,189],"transfected":[170,203],"with":[171,204],"DANCR-targeting":[172,205],"siRNA.":[173,206],"addition,":[175],"compromised":[178],"inhibition":[179],"transition":[183],"caused":[184],"silencing.":[187],"Furthermore,":[188],"accumulation":[193],"Conclusion:":[207],"modulates":[209],"growth":[210],"metastasis":[212],"targeting":[214],"miR-216a/LGR5":[216],"axis":[217],"PI3K/AKT":[219],"signaling":[220],"pathway.":[221],"Keywords:":[222],"glioma,":[223],"angiogenesis,":[226],"DANCR,":[227]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-04-11T00:00:00"}