{"id":"https://openalex.org/W2928906193","doi":"https://doi.org/10.17650/2222-1468-2019-9-1-12-19","title":"Contrast-enhanced ultrasound in the diagnosis of head and neck squamous cell carcinoma","display_name":"Contrast-enhanced ultrasound in the diagnosis of head and neck squamous cell carcinoma","publication_year":2019,"publication_date":"2019-04-02","ids":{"openalex":"https://openalex.org/W2928906193","doi":"https://doi.org/10.17650/2222-1468-2019-9-1-12-19","mag":"2928906193"},"language":"en","primary_location":{"id":"doi:10.17650/2222-1468-2019-9-1-12-19","doi":"https://doi.org/10.17650/2222-1468-2019-9-1-12-19","is_oa":true,"landing_page_url":"https://doi.org/10.17650/2222-1468-2019-9-1-12-19","pdf_url":"https://ogsh.abvpress.ru/jour/article/download/384/361","source":{"id":"https://openalex.org/S2738175511","display_name":"Head and neck tumors (HNT)","issn_l":"2222-1468","issn":["2222-1468","2411-4634"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310312679","host_organization_name":"ABV-press","host_organization_lineage":["https://openalex.org/P4310312679"],"host_organization_lineage_names":["ABV-press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Head and neck tumors (HNT)","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://ogsh.abvpress.ru/jour/article/download/384/361","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5078001831","display_name":"\u0410\u043b\u043b\u0430\u0445\u0432\u0435\u0440\u0434\u0438\u0435\u0432\u0430 \u0413\u043e\u043d\u0447\u0430 \u0424\u0430\u0440\u0438\u0434\u043e\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0001-5910-5892","observed_orcids":["https://orcid.org/0000-0001-5910-5892"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"G. F. Allakhverdieva","raw_affiliation_strings":["N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia"],"raw_orcid":"https://orcid.org/0000-0001-5910-5892","affiliations":[{"raw_affiliation_string":"N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067627271","display_name":"\u0421\u0438\u043d\u044e\u043a\u043e\u0432\u0430 \u0413\u0430\u043b\u0438\u043d\u0430 \u0422\u0438\u043c\u043e\u0444\u0435\u0435\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0002-5697-9268","observed_orcids":["https://orcid.org/0000-0002-5697-9268"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"G. T. Sinyukova","raw_affiliation_strings":["N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010682438","display_name":"\u0422. Yu. Danzanova","orcid":"https://orcid.org/0000-0002-6171-6796","observed_orcids":["https://orcid.org/0000-0002-6171-6796"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"T. Yu. Danzanova","raw_affiliation_strings":["N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia"],"raw_orcid":"https://orcid.org/0000-0002-6171-6796","affiliations":[{"raw_affiliation_string":"N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077577666","display_name":"\u0415. \u0412. \u041a\u043e\u0432\u0430\u043b\u0435\u0432\u0430","orcid":"https://orcid.org/0000-0003-4567-9160","observed_orcids":["https://orcid.org/0000-0003-4567-9160"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"E. V. Kovaleva","raw_affiliation_strings":["N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082447869","display_name":"\u041e. \u0410. \u0421\u0430\u043f\u0440\u0438\u043d\u0430","orcid":"https://orcid.org/0000-0002-2283-1812","observed_orcids":["https://orcid.org/0000-0002-2283-1812"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"O. A. Saprina","raw_affiliation_strings":["N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5058325646","display_name":"\u0413\u0443\u0434\u0438\u043b\u0438\u043d\u0430 \u0415\u043b\u0435\u043d\u0430 \u0410\u043d\u0430\u0442\u043e\u043b\u044c\u0435\u0432\u043d\u0430","orcid":"https://orcid.org/0000-0003-0653-3820","observed_orcids":["https://orcid.org/0000-0003-0653-3820"]},"institutions":[{"id":"https://openalex.org/I4210090957","display_name":"Russian Cancer Research Center NN Blokhin","ror":"https://ror.org/00ab9fg88","country_code":"RU","type":"facility","lineage":["https://openalex.org/I4210090957"]},{"id":"https://openalex.org/I4210117042","display_name":"Ministry of Health of the Russian Federation","ror":"https://ror.org/01p8ehb87","country_code":"RU","type":"government","lineage":["https://openalex.org/I4210117042"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"E. A. Gudilina","raw_affiliation_strings":["N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia"],"raw_orcid":"https://orcid.org/0000-0003-0653-3820","affiliations":[{"raw_affiliation_string":"N.N. Blokhin National Medical Research Center of Oncology, Ministry of Health of Russia","institution_ids":["https://openalex.org/I4210090957","https://openalex.org/I4210117042"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.4545,"has_fulltext":true,"cited_by_count":4,"citation_normalized_percentile":{"value":0.60082178,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"9","issue":"1","first_page":"12","last_page":"19"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.6836000084877014,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.6836000084877014,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.1639000028371811,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10727","display_name":"Ultrasound Imaging and Elastography","score":0.05310000106692314,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/contrast-enhanced-ultrasound","display_name":"contrast-enhanced ultrasound","score":0.996999979019165},{"id":"https://openalex.org/keywords/head-and-neck-squamous-cell-carcinoma","display_name":"head and neck squamous cell carcinoma","score":0.9330000281333923},{"id":"https://openalex.org/keywords/sulfur-hexafluoride","display_name":"sulfur hexafluoride","score":0.949999988079071},{"id":"https://openalex.org/keywords/tumor-recurrence-detection","display_name":"tumor recurrence detection","score":0.7710000276565552},{"id":"https://openalex.org/keywords/laryngeal-tumors","display_name":"laryngeal tumors","score":0.8379999995231628},{"id":"https://openalex.org/keywords/laryngopharyngeal-cancer","display_name":"laryngopharyngeal cancer","score":0.8479999899864197},{"id":"https://openalex.org/keywords/vocal-cord-visualization","display_name":"vocal cord visualization","score":0.7549999952316284},{"id":"https://openalex.org/keywords/laryngeal-cartilages","display_name":"laryngeal cartilages","score":0.7699999809265137},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.44999998807907104}],"concepts":[{"id":"https://openalex.org/C206111553","wikidata":"https://www.wikidata.org/wiki/Q3501532","display_name":"Echogenicity","level":3,"score":0.8146364688873291},{"id":"https://openalex.org/C2780474809","wikidata":"https://www.wikidata.org/wiki/Q9637","display_name":"Larynx","level":2,"score":0.7381280064582825},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7112526893615723},{"id":"https://openalex.org/C143753070","wikidata":"https://www.wikidata.org/wiki/Q162564","display_name":"Ultrasound","level":2,"score":0.6727190017700195},{"id":"https://openalex.org/C2776502983","wikidata":"https://www.wikidata.org/wiki/Q690182","display_name":"Contrast (vision)","level":2,"score":0.5409392714500427},{"id":"https://openalex.org/C3018411727","wikidata":"https://www.wikidata.org/wiki/Q3867488","display_name":"Head and neck","level":2,"score":0.5174294114112854},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.4680668115615845},{"id":"https://openalex.org/C3018181011","wikidata":"https://www.wikidata.org/wiki/Q6849688","display_name":"Contrast enhancement","level":3,"score":0.4547230303287506},{"id":"https://openalex.org/C3019992690","wikidata":"https://www.wikidata.org/wiki/Q92767510","display_name":"Basal cell","level":2,"score":0.45354974269866943},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.4431169927120209},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.16821932792663574},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.1018151044845581},{"id":"https://openalex.org/C143409427","wikidata":"https://www.wikidata.org/wiki/Q161238","display_name":"Magnetic resonance imaging","level":2,"score":0.08651897311210632},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.17650/2222-1468-2019-9-1-12-19","doi":"https://doi.org/10.17650/2222-1468-2019-9-1-12-19","is_oa":true,"landing_page_url":"https://doi.org/10.17650/2222-1468-2019-9-1-12-19","pdf_url":"https://ogsh.abvpress.ru/jour/article/download/384/361","source":{"id":"https://openalex.org/S2738175511","display_name":"Head and neck tumors (HNT)","issn_l":"2222-1468","issn":["2222-1468","2411-4634"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310312679","host_organization_name":"ABV-press","host_organization_lineage":["https://openalex.org/P4310312679"],"host_organization_lineage_names":["ABV-press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Head and neck tumors (HNT)","raw_type":"journal-article"}],"best_oa_location":{"id":"doi:10.17650/2222-1468-2019-9-1-12-19","doi":"https://doi.org/10.17650/2222-1468-2019-9-1-12-19","is_oa":true,"landing_page_url":"https://doi.org/10.17650/2222-1468-2019-9-1-12-19","pdf_url":"https://ogsh.abvpress.ru/jour/article/download/384/361","source":{"id":"https://openalex.org/S2738175511","display_name":"Head and neck tumors (HNT)","issn_l":"2222-1468","issn":["2222-1468","2411-4634"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310312679","host_organization_name":"ABV-press","host_organization_lineage":["https://openalex.org/P4310312679"],"host_organization_lineage_names":["ABV-press"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Head and neck tumors (HNT)","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2928906193.pdf","grobid_xml":"https://content.openalex.org/works/W2928906193.grobid-xml"},"referenced_works_count":13,"referenced_works":["https://openalex.org/W594757686","https://openalex.org/W1980305246","https://openalex.org/W1981989535","https://openalex.org/W2011945218","https://openalex.org/W2041246059","https://openalex.org/W2130141130","https://openalex.org/W2139348853","https://openalex.org/W2143680521","https://openalex.org/W2156653782","https://openalex.org/W2161890956","https://openalex.org/W2416860113","https://openalex.org/W2566758040","https://openalex.org/W2791941118"],"related_works":["https://openalex.org/W2962856658","https://openalex.org/W1967894460","https://openalex.org/W3066900871","https://openalex.org/W2333685018","https://openalex.org/W4391560256","https://openalex.org/W4200358393","https://openalex.org/W7131996456","https://openalex.org/W4410444835","https://openalex.org/W2004368131","https://openalex.org/W4406129089"],"abstract_inverted_index":{"The":[0],"study":[1],"objective":[2],"is":[3,223,247,288],"to":[4,283],"evaluate":[5],"the":[6,12,57,107,115,130,136,185,204,211,218,243,263,267,270,284],"capacity":[7],"of":[8,14,34,47,59,71,132,144,203,214,217,236,242,266,280],"contrast-enhanced":[9,39],"ultrasound":[10,40,198,215,240],"in":[11,106,135],"diagnosis":[13],"head":[15,28,244],"and":[16,21,29,49,69,110,122,147,151,155,171,245,275,278,293],"neck":[17,30,246],"squamous":[18,163],"cell":[19,164],"carcinoma.Materials":[20],"methods.":[22],"We":[23],"examined":[24],"34":[25],"patients":[26,91],"with":[27,42,92,260],"tumors":[31,51,76,134,140,153,274],"(or":[32],"suspected":[33,93],"having":[35],"a":[36,248],"tumor)":[37],"using":[38],"imaging":[41,199,241],"sulfur":[43],"hexafluoride.Results.":[44],"Contrast":[45],"enhancement":[46,146],"primary":[48,88],"recurrent":[50,75],"(developed":[52,77],"within":[53,78],"3":[54],"months":[55,80],"since":[56],"end":[58],"treatment)":[60,82],"was":[61,96],"characterized":[62],"by":[63,99,225],"rapid":[64,142],"wash-in":[65,86,121],"(including":[66],"peak":[67,145],"enhancement)":[68],"wash-out":[70,123],"contrast":[72,102,157,174,180],"agent.":[73,175],"However,":[74],"\uf0b33":[79],"after":[81],"demonstrated":[83,141],"slightly":[84],"slower":[85],"than":[87],"tumors.":[89],"In":[90],"relapse,":[94],"which":[95,182,287],"not":[97,112,128],"confirmed":[98],"histological":[100],"examination,":[101],"agent":[103,158],"accumulated":[104],"only":[105],"surrounding":[108],"tissues":[109],"did":[111,127],"penetrate":[113],"into":[114],"fibrous":[116],"infiltrate;":[117],"there":[118],"were":[119],"no":[120],"phases":[124],"(although":[125],"this":[126],"exclude":[129],"presence":[131],"small":[133],"infiltrate).":[137],"By":[138],"contrast,":[139],"achievement":[143],"fast":[148],"wash-out.":[149],"Laryngeal":[150,166],"laryngopharyngeal":[152],"accumulate":[154,173,179],"release":[156],"like":[159],"any":[160],"other":[161],"oropharyngeal":[162],"carcinomas.":[165],"cartilages":[167],"have":[168],"high":[169],"echogenicity":[170],"don\u2019t":[172],"Tumor-altered":[176],"vocal":[177,188,205],"cords":[178,189],"agent,":[181],"significantly":[183,209],"improves":[184],"visualization.":[186],"Intact":[187],"appear":[190],"as":[191,230],"hyperechogenic":[192],"symmetric":[193],"structures":[194],"on":[195],"B-scans.":[196],"Contrast-enhanced":[197,239],"allows":[200],"better":[201],"visualization":[202,259],"cords.":[206],"Contrast-enhancement":[207],"can":[208],"improve":[210],"diagnostic":[212,251,264],"value":[213,265],"examination":[216],"larynx,":[219],"especially":[220],"when":[221],"B-scanning":[222],"hindered":[224],"some":[226],"anatomical":[227],"features":[228],"(such":[229],"large":[231],"Adam\u2019s":[232],"apple)":[233],"or":[234],"ossification":[235],"laryngeal":[237,285],"cartilages.Conclusion.":[238],"highly":[249],"promising":[250],"tool,":[252],"although":[253],"it":[254],"requires":[255],"further":[256],"evaluation.":[257],"Improved":[258],"contrast-enhancement":[261],"increases":[262],"method":[268],"for":[269,290],"differentiation":[271],"between":[272],"various":[273],"fibrotic":[276],"changes":[277],"detection":[279],"tumor":[281],"spread":[282],"cartilages,":[286],"important":[289],"surgical":[291],"treatment":[292],"planning":[294],"anticancer":[295],"therapy.":[296]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2019-04-11T00:00:00"}