{"id":"https://openalex.org/W2927691990","doi":"https://doi.org/10.1021/acsbiomaterials.9b00177","title":"Proteome-wide Analysis of Cellular Response to Ultraviolet Light for Biomaterial Synthesis and Modification","display_name":"Proteome-wide Analysis of Cellular Response to Ultraviolet Light for Biomaterial Synthesis and Modification","publication_year":2019,"publication_date":"2019-04-05","ids":{"openalex":"https://openalex.org/W2927691990","doi":"https://doi.org/10.1021/acsbiomaterials.9b00177","mag":"2927691990","pmid":"https://pubmed.ncbi.nlm.nih.gov/33405713"},"language":"en","primary_location":{"id":"doi:10.1021/acsbiomaterials.9b00177","doi":"https://doi.org/10.1021/acsbiomaterials.9b00177","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsbiomaterials.9b00177","pdf_url":null,"source":{"id":"https://openalex.org/S2764739176","display_name":"ACS Biomaterials Science & Engineering","issn_l":"2373-9878","issn":["2373-9878"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Biomaterials Science & Engineering","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053819812","display_name":"Emily R. Ruskowitz","orcid":"https://orcid.org/0000-0001-8772-4869","observed_orcids":["https://orcid.org/0000-0001-8772-4869"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Emily R. Ruskowitz","raw_affiliation_strings":["Department of Chemical Engineering, University of Washington, Seattle, Washington 98195, United States"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemical Engineering, University of Washington, Seattle, Washington 98195, United States","institution_ids":["https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5030286069","display_name":"Cole A. DeForest","orcid":"https://orcid.org/0000-0003-0337-3577","observed_orcids":["https://orcid.org/0000-0003-0337-3577"]},"institutions":[{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Cole A. DeForest","raw_affiliation_strings":["Institute of Stem Cell & Regenerative Medicine, University of Washington, Seattle, Washington 98109, United States"],"raw_orcid":"https://orcid.org/0000-0003-0337-3577","affiliations":[{"raw_affiliation_string":"Institute of Stem Cell & Regenerative Medicine, University of Washington, Seattle, Washington 98109, United States","institution_ids":["https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5030286069"],"corresponding_institution_ids":["https://openalex.org/I201448701"],"apc_list":{"value":5000,"currency":"USD","value_usd":5000},"apc_paid":null,"fwci":4.2943,"has_fulltext":false,"cited_by_count":82,"citation_normalized_percentile":{"value":0.96233243,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":99},"biblio":{"volume":"5","issue":"5","first_page":"2111","last_page":"2116"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12570","display_name":"Photopolymerization techniques and applications","score":0.32839998602867126,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12570","display_name":"Photopolymerization techniques and applications","score":0.32839998602867126,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11190","display_name":"3D Printing in Biomedical Research","score":0.1421000063419342,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.08449999988079071,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/near-ultraviolet-light","display_name":"near-ultraviolet light","score":0.8759999871253967},{"id":"https://openalex.org/keywords/365-nm-irradiation","display_name":"365 nm irradiation","score":0.8240000009536743},{"id":"https://openalex.org/keywords/proteome","display_name":"proteome","score":0.6869999766349792},{"id":"https://openalex.org/keywords/nih-3t3-cells","display_name":"NIH3T3 cells","score":0.9470000267028809},{"id":"https://openalex.org/keywords/human-mesenchymal-stem-cells","display_name":"human mesenchymal stem cells","score":0.9570000171661377},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.5419999957084656},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.9950000047683716},{"id":"https://openalex.org/keywords/biomaterial-synthesis","display_name":"biomaterial synthesis","score":0.6729999780654907},{"id":"https://openalex.org/keywords/biomaterial-modification","display_name":"biomaterial modification","score":0.8309999704360962},{"id":"https://openalex.org/keywords/3d-cell-culture-scaffolds","display_name":"3D cell culture scaffolds","score":0.9049999713897705},{"id":"https://openalex.org/keywords/tissue-engineering","display_name":"tissue engineering","score":0.9639999866485596}],"concepts":[{"id":"https://openalex.org/C2778414984","wikidata":"https://www.wikidata.org/wiki/Q865663","display_name":"Biomaterial","level":2,"score":0.8174229264259338},{"id":"https://openalex.org/C198826908","wikidata":"https://www.wikidata.org/wiki/Q1922379","display_name":"Mesenchymal stem cell","level":2,"score":0.6864997744560242},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.608461856842041},{"id":"https://openalex.org/C2987116853","wikidata":"https://www.wikidata.org/wiki/Q11391","display_name":"Ultraviolet light","level":2,"score":0.6077845692634583},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5673079490661621},{"id":"https://openalex.org/C104397665","wikidata":"https://www.wikidata.org/wiki/Q860947","display_name":"Proteome","level":2,"score":0.5170508027076721},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.4955095052719116},{"id":"https://openalex.org/C62112901","wikidata":"https://www.wikidata.org/wiki/Q189159","display_name":"Cell growth","level":2,"score":0.4884854555130005},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.42055800557136536},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.42003610730171204},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3957896828651428},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.34120190143585205},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3301798701286316},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.31245851516723633},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18930625915527344},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.17993170022964478},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.10746824741363525},{"id":"https://openalex.org/C49040817","wikidata":"https://www.wikidata.org/wiki/Q193091","display_name":"Optoelectronics","level":1,"score":0.06381571292877197},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1021/acsbiomaterials.9b00177","doi":"https://doi.org/10.1021/acsbiomaterials.9b00177","is_oa":false,"landing_page_url":"https://doi.org/10.1021/acsbiomaterials.9b00177","pdf_url":null,"source":{"id":"https://openalex.org/S2764739176","display_name":"ACS Biomaterials Science & Engineering","issn_l":"2373-9878","issn":["2373-9878"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4310320006","host_organization_name":"American Chemical Society","host_organization_lineage":["https://openalex.org/P4310320006"],"host_organization_lineage_names":["American Chemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS Biomaterials Science & Engineering","raw_type":"journal-article"},{"id":"pmid:33405713","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/33405713","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ACS biomaterials science & engineering","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4000000059604645,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G3045622058","display_name":"Spatiotemporally Resolved Proteomics through Photomediated Protein Labeling","funder_award_id":"1803054","funder_id":"https://openalex.org/F4320306076","funder_display_name":"National Science Foundation"}],"funders":[{"id":"https://openalex.org/F4320306076","display_name":"National Science Foundation","ror":"https://ror.org/021nxhr62"},{"id":"https://openalex.org/F4320310094","display_name":"University of Washington","ror":"https://ror.org/00cvxb145"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1969252837","https://openalex.org/W1973268693","https://openalex.org/W1992294575","https://openalex.org/W2011769238","https://openalex.org/W2019108282","https://openalex.org/W2036213518","https://openalex.org/W2036321220","https://openalex.org/W2049836457","https://openalex.org/W2051920559","https://openalex.org/W2056826119","https://openalex.org/W2059028566","https://openalex.org/W2060201374","https://openalex.org/W2067897176","https://openalex.org/W2070855956","https://openalex.org/W2080752012","https://openalex.org/W2083880695","https://openalex.org/W2086375279","https://openalex.org/W2088868630","https://openalex.org/W2092769914","https://openalex.org/W2151501496","https://openalex.org/W2225625486","https://openalex.org/W2463195069","https://openalex.org/W2520756668","https://openalex.org/W2537623931","https://openalex.org/W2739343374","https://openalex.org/W2778217919","https://openalex.org/W2783235643","https://openalex.org/W2787477665","https://openalex.org/W2888268024"],"related_works":["https://openalex.org/W2225625486","https://openalex.org/W7096182957","https://openalex.org/W1970649584","https://openalex.org/W2087391894","https://openalex.org/W3008933977","https://openalex.org/W1988407579","https://openalex.org/W2403955588","https://openalex.org/W2043540425","https://openalex.org/W2318430936","https://openalex.org/W2261657116"],"abstract_inverted_index":{"Though":[0],"the":[1,22,38],"biomaterials":[2],"community":[3],"has":[4,31],"widely":[5],"utilized":[6],"near-ultraviolet":[7],"(UV)":[8],"light":[9,27,43,77],"to":[10],"make":[11],"and":[12,48,69],"modify":[13],"scaffolds":[14],"for":[15],"3D":[16],"cell":[17,29,54,95],"culture,":[18],"thorough":[19],"examination":[20],"of":[21,25,41,66],"downstream":[23],"effects":[24,40],"such":[26],"on":[28,45],"function":[30],"not":[32],"been":[33],"performed.":[34],"Here,":[35],"we":[36],"investigate":[37],"global":[39],"common":[42],"treatments":[44],"NIH3T3":[46],"fibroblasts":[47],"human":[49],"mesenchymal":[50],"stem":[51],"cells":[52],"(hMSCs),":[53],"types":[55],"regularly":[56],"employed":[57],"in":[58,89],"tissue":[59],"engineering.":[60],"Unchanged":[61],"proliferation":[62],"rates,":[63],"an":[64,70],"absence":[65],"apoptotic":[67],"induction,":[68],"unaltered":[71],"proteome":[72],"following":[73],"low-dose":[74],"365":[75],"nm":[76],"exposure":[78],"are":[79],"observed,":[80],"implying":[81],"that":[82],"near-UV-based":[83],"radical-free":[84],"photochemistries":[85],"can":[86],"be":[87],"exploited":[88],"biomaterial":[90],"systems":[91],"without":[92],"deleteriously":[93],"affecting":[94],"fate.":[96]},"counts_by_year":[{"year":2026,"cited_by_count":10},{"year":2025,"cited_by_count":5},{"year":2024,"cited_by_count":13},{"year":2023,"cited_by_count":9},{"year":2022,"cited_by_count":10},{"year":2021,"cited_by_count":14},{"year":2020,"cited_by_count":14},{"year":2019,"cited_by_count":7}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-04-11T00:00:00"}