{"id":"https://openalex.org/W2925208342","doi":"https://doi.org/10.1002/hbm.24565","title":"Gesturing tool use and tool transport actions modulates inferior parietal functional connectivity with the dorsal and ventral object processing pathways","display_name":"Gesturing tool use and tool transport actions modulates inferior parietal functional connectivity with the dorsal and ventral object processing pathways","publication_year":2019,"publication_date":"2019-03-21","ids":{"openalex":"https://openalex.org/W2925208342","doi":"https://doi.org/10.1002/hbm.24565","mag":"2925208342","pmid":"https://pubmed.ncbi.nlm.nih.gov/30900321","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6548598"},"language":"en","primary_location":{"id":"doi:10.1002/hbm.24565","doi":"https://doi.org/10.1002/hbm.24565","is_oa":true,"landing_page_url":"https://doi.org/10.1002/hbm.24565","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hbm.24565","source":{"id":"https://openalex.org/S121666818","display_name":"Human Brain Mapping","issn_l":"1065-9471","issn":["1065-9471","1097-0193"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Brain Mapping","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hbm.24565","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5020204985","display_name":"Frank E. Garcea","orcid":"https://orcid.org/0000-0002-8843-9127","observed_orcids":["https://orcid.org/0000-0002-8843-9127"]},"institutions":[{"id":"https://openalex.org/I4210111876","display_name":"Einstein Healthcare Network","ror":"https://ror.org/01bh2s525","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111876"]},{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Frank E. Garcea","raw_affiliation_strings":["Cognitive Neuroscience, University of Pennsylvania  Philadelphia Pennsylvania","Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network  Elkins Park Pennsylvania"],"raw_orcid":"https://orcid.org/0000-0002-8843-9127","affiliations":[{"raw_affiliation_string":"Cognitive Neuroscience, University of Pennsylvania  Philadelphia Pennsylvania","institution_ids":["https://openalex.org/I79576946"]},{"raw_affiliation_string":"Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network  Elkins Park Pennsylvania","institution_ids":["https://openalex.org/I4210111876"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049136249","display_name":"Laurel J. Buxbaum","orcid":"https://orcid.org/0000-0003-2421-5455","observed_orcids":["https://orcid.org/0000-0003-2421-5455"]},"institutions":[{"id":"https://openalex.org/I149251103","display_name":"Thomas Jefferson University","ror":"https://ror.org/00ysqcn41","country_code":"US","type":"education","lineage":["https://openalex.org/I149251103"]},{"id":"https://openalex.org/I4210111876","display_name":"Einstein Healthcare Network","ror":"https://ror.org/01bh2s525","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210111876"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Laurel J. Buxbaum","raw_affiliation_strings":["Department of Rehabilitation Medicine Thomas Jefferson University  Philadelphia Pennsylvania","Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network  Elkins Park Pennsylvania"],"raw_orcid":"https://orcid.org/0000-0003-2421-5455","affiliations":[{"raw_affiliation_string":"Department of Rehabilitation Medicine Thomas Jefferson University  Philadelphia Pennsylvania","institution_ids":["https://openalex.org/I149251103"]},{"raw_affiliation_string":"Moss Rehabilitation Research Institute, Albert Einstein Healthcare Network  Elkins Park Pennsylvania","institution_ids":["https://openalex.org/I4210111876"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5020204985"],"corresponding_institution_ids":["https://openalex.org/I4210111876","https://openalex.org/I79576946"],"apc_list":{"value":4250,"currency":"USD","value_usd":4250},"apc_paid":null,"fwci":5.2113,"has_fulltext":false,"cited_by_count":45,"citation_normalized_percentile":{"value":0.94762468,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"40","issue":"10","first_page":"2867","last_page":"2883"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11431","display_name":"Action Observation and Synchronization","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T11431","display_name":"Action Observation and Synchronization","score":0.8252000212669373,"subfield":{"id":"https://openalex.org/subfields/3207","display_name":"Social Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10982","display_name":"Motor Control and Adaptation","score":0.07540000230073929,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10465","display_name":"Neurobiology of Language and Bilingualism","score":0.02800000086426735,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tool-use","display_name":"tool use","score":0.8730000257492065},{"id":"https://openalex.org/keywords/gesturing","display_name":"gesturing","score":0.8410000205039978},{"id":"https://openalex.org/keywords/inferior-parietal-cortex","display_name":"inferior parietal cortex","score":0.7879999876022339},{"id":"https://openalex.org/keywords/supramarginal-gyrus","display_name":"supramarginal gyrus","score":0.9929999709129333},{"id":"https://openalex.org/keywords/functional-connectivity","display_name":"functional connectivity","score":0.7680000066757202},{"id":"https://openalex.org/keywords/dorsal-visual-pathway","display_name":"dorsal visual pathway","score":0.8320000171661377},{"id":"https://openalex.org/keywords/ventral-stream","display_name":"ventral stream","score":0.9909999966621399},{"id":"https://openalex.org/keywords/object-processing","display_name":"object processing","score":0.8019999861717224},{"id":"https://openalex.org/keywords/grasping","display_name":"grasping","score":0.6269999742507935},{"id":"https://openalex.org/keywords/action-planning","display_name":"action planning","score":0.6819999814033508},{"id":"https://openalex.org/keywords/fusiform-gyrus","display_name":"fusiform gyrus","score":0.7680000066757202},{"id":"https://openalex.org/keywords/frontal-operculum","display_name":"frontal operculum","score":0.7070000171661377},{"id":"https://openalex.org/keywords/posterior-intraparietal-sulcus","display_name":"posterior intraparietal sulcus","score":0.843999981880188}],"concepts":[{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.7247719168663025},{"id":"https://openalex.org/C140530291","wikidata":"https://www.wikidata.org/wiki/Q1225063","display_name":"Dorsum","level":2,"score":0.7243191003799438},{"id":"https://openalex.org/C3018011982","wikidata":"https://www.wikidata.org/wiki/Q7316120","display_name":"Functional connectivity","level":2,"score":0.5260812044143677},{"id":"https://openalex.org/C2777944498","wikidata":"https://www.wikidata.org/wiki/Q6412501","display_name":"Inferior parietal lobule","level":3,"score":0.4580823481082916},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.3936993479728699},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.34679511189460754},{"id":"https://openalex.org/C46312422","wikidata":"https://www.wikidata.org/wiki/Q11024","display_name":"Communication","level":1,"score":0.340109646320343},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3268207311630249},{"id":"https://openalex.org/C2779226451","wikidata":"https://www.wikidata.org/wiki/Q903809","display_name":"Functional magnetic resonance imaging","level":2,"score":0.27801513671875}],"mesh":[{"descriptor_ui":"D001931","descriptor_name":"Brain Mapping","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005868","descriptor_name":"Gestures","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010296","descriptor_name":"Parietal Lobe","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D011597","descriptor_name":"Psychomotor Performance","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D014795","descriptor_name":"Visual Pathways","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D053001","descriptor_name":"Tool Use Behavior","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/hbm.24565","doi":"https://doi.org/10.1002/hbm.24565","is_oa":true,"landing_page_url":"https://doi.org/10.1002/hbm.24565","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hbm.24565","source":{"id":"https://openalex.org/S121666818","display_name":"Human Brain Mapping","issn_l":"1065-9471","issn":["1065-9471","1097-0193"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Brain Mapping","raw_type":"journal-article"},{"id":"pmid:30900321","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30900321","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human brain mapping","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6548598","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6548598/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Hum Brain Mapp","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1002/hbm.24565","doi":"https://doi.org/10.1002/hbm.24565","is_oa":true,"landing_page_url":"https://doi.org/10.1002/hbm.24565","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/hbm.24565","source":{"id":"https://openalex.org/S121666818","display_name":"Human Brain Mapping","issn_l":"1065-9471","issn":["1065-9471","1097-0193"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","erih-plus","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Human Brain Mapping","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G8059906800","display_name":"Understanding Action Selection in the Tool Use Network","funder_award_id":"R01NS099061","funder_id":"https://openalex.org/F4320337359","funder_display_name":"National Institute of Neurological Disorders and Stroke"},{"id":"https://openalex.org/G8155634172","display_name":"Postdoctoral Training in Translational Neurorehabilitation Research","funder_award_id":"T32HD071844","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"}],"funders":[{"id":"https://openalex.org/F4320309370","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","ror":"https://ror.org/01s5ya894"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"pdf":true,"grobid_xml":false},"content_urls":{"pdf":"https://content.openalex.org/works/W2925208342.pdf"},"referenced_works_count":79,"referenced_works":["https://openalex.org/W7508719","https://openalex.org/W830163325","https://openalex.org/W1595033594","https://openalex.org/W1963193125","https://openalex.org/W1964265800","https://openalex.org/W1965025745","https://openalex.org/W1965491986","https://openalex.org/W1975752615","https://openalex.org/W1978154168","https://openalex.org/W1979129202","https://openalex.org/W1999409707","https://openalex.org/W2011789891","https://openalex.org/W2015016650","https://openalex.org/W2015866962","https://openalex.org/W2021142655","https://openalex.org/W2029072098","https://openalex.org/W2029456941","https://openalex.org/W2029818825","https://openalex.org/W2033940434","https://openalex.org/W2035083507","https://openalex.org/W2036216439","https://openalex.org/W2039870632","https://openalex.org/W2040392196","https://openalex.org/W2041127567","https://openalex.org/W2044820817","https://openalex.org/W2045334960","https://openalex.org/W2046097950","https://openalex.org/W2046510061","https://openalex.org/W2052148080","https://openalex.org/W2059011032","https://openalex.org/W2068782491","https://openalex.org/W2077116199","https://openalex.org/W2079247946","https://openalex.org/W2090808976","https://openalex.org/W2092954611","https://openalex.org/W2093357285","https://openalex.org/W2094622968","https://openalex.org/W2098456117","https://openalex.org/W2099259699","https://openalex.org/W2100223265","https://openalex.org/W2113589953","https://openalex.org/W2118125647","https://openalex.org/W2120187808","https://openalex.org/W2121284801","https://openalex.org/W2121537073","https://openalex.org/W2124777086","https://openalex.org/W2127445969","https://openalex.org/W2135851646","https://openalex.org/W2136022845","https://openalex.org/W2137994045","https://openalex.org/W2140007015","https://openalex.org/W2141260237","https://openalex.org/W2143333433","https://openalex.org/W2144201014","https://openalex.org/W2144922484","https://openalex.org/W2145438605","https://openalex.org/W2149989625","https://openalex.org/W2152670257","https://openalex.org/W2165116114","https://openalex.org/W2167875271","https://openalex.org/W2278105351","https://openalex.org/W2336666904","https://openalex.org/W2341835294","https://openalex.org/W2460367489","https://openalex.org/W2508691184","https://openalex.org/W2550505525","https://openalex.org/W2554584321","https://openalex.org/W2592598776","https://openalex.org/W2596739206","https://openalex.org/W2603868268","https://openalex.org/W2622243750","https://openalex.org/W2622983518","https://openalex.org/W2744354842","https://openalex.org/W2790096320","https://openalex.org/W2791380825","https://openalex.org/W2800010908","https://openalex.org/W2888892231","https://openalex.org/W2890441972","https://openalex.org/W3133789429"],"related_works":["https://openalex.org/W2135615192","https://openalex.org/W2791380825","https://openalex.org/W2968714539","https://openalex.org/W2094622968","https://openalex.org/W2046097950","https://openalex.org/W4318755554","https://openalex.org/W2036224475","https://openalex.org/W2086427063","https://openalex.org/W1243424149","https://openalex.org/W2092954611"],"abstract_inverted_index":{"Interacting":[0],"with":[1,45],"manipulable":[2],"objects":[3],"(tools)":[4],"requires":[5],"the":[6,22,36,57,64,102,133,160,180,188,192],"integration":[7,37],"of":[8,38,51,194],"diverse":[9],"computations":[10],"supported":[11],"by":[12,166,179],"anatomically":[13],"remote":[14],"regions.":[15],"Previous":[16],"functional":[17,27,85,99,130,157],"neuroimaging":[18],"research":[19],"has":[20],"demonstrated":[21],"left":[23,65,103,134,136,142,161],"supramarginal":[24],"(SMG)":[25],"exhibits":[26],"connectivity":[28,100,131,158],"to":[29,59,159],"both":[30],"ventral":[31,67,105,137],"and":[32,42,48,70,80,111,127,141,151,169],"dorsal":[33,71,112],"pathways,":[34],"supporting":[35],"ventrally-mediated":[39],"tool":[40,124,148,167,170,176],"properties":[41],"conceptual":[43],"knowledge":[44],"dorsally-computed":[46],"volumetric":[47],"structural":[49],"representations":[50],"tools.":[52],"This":[53],"architecture":[54],"affords":[55],"us":[56],"opportunity":[58],"test":[60],"whether":[61],"interactions":[62],"between":[63,101,132],"SMG,":[66,104,135],"visual":[68,72,113],"pathway,":[69],"pathway":[73,114],"are":[74,185],"differentially":[75,164],"modulated":[76,165],"when":[77],"participants":[78],"plan":[79],"generate":[81],"tool-directed":[82,195],"gestures":[83],"emphasizing":[84],"manipulation":[86],"(tool":[87,93],"use":[88,149,168],"gesturing)":[89],"or":[90],"structure-based":[91],"grasping":[92],"transport":[94,125,171],"gesturing).":[95],"We":[96],"found":[97],"that":[98,156,174],"temporal":[106,139],"cortex":[107],"(bilateral":[108],"fusiform":[109],"gyri),":[110],"(left":[115],"superior":[116],"parietal":[117,189],"lobule/posterior":[118],"intraparietal":[119],"sulcus)":[120],"was":[121,145],"maximal":[122,146],"for":[123,147],"planning":[126,150],"gesturing,":[128,172],"whereas":[129],"anterior":[138],"lobe,":[140],"frontal":[143],"operculum":[144],"gesturing.":[152],"These":[153],"results":[154],"demonstrate":[155],"SMG":[162],"is":[163],"suggesting":[173],"distinct":[175],"features":[177],"computed":[178],"two":[181],"object":[182],"processing":[183],"pathways":[184],"integrated":[186],"in":[187,191],"lobe":[190],"service":[193],"action.":[196]},"counts_by_year":[{"year":2026,"cited_by_count":6},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":8},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-04-01T00:00:00"}