{"id":"https://openalex.org/W2923913614","doi":"https://doi.org/10.1016/j.steroids.2019.03.005","title":"Metabolism of formestane in humans: Identification of urinary biomarkers for antidoping analysis","display_name":"Metabolism of formestane in humans: Identification of urinary biomarkers for antidoping analysis","publication_year":2019,"publication_date":"2019-03-20","ids":{"openalex":"https://openalex.org/W2923913614","doi":"https://doi.org/10.1016/j.steroids.2019.03.005","mag":"2923913614","pmid":"https://pubmed.ncbi.nlm.nih.gov/30904502"},"language":"en","primary_location":{"id":"doi:10.1016/j.steroids.2019.03.005","doi":"https://doi.org/10.1016/j.steroids.2019.03.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.steroids.2019.03.005","pdf_url":"https://ars.els-cdn.com/content/image/1-s2.0-S0039128X1930056X-ga1_lrg.jpg","source":{"id":"https://openalex.org/S70286497","display_name":"Steroids","issn_l":"0039-128X","issn":["0039-128X","1878-5867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Steroids","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://ars.els-cdn.com/content/image/1-s2.0-S0039128X1930056X-ga1_lrg.jpg","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5025398873","display_name":"Xavier de la Torre","orcid":"https://orcid.org/0000-0001-8037-6750","observed_orcids":["https://orcid.org/0000-0001-8037-6750"]},"institutions":[{"id":"https://openalex.org/I4210118979","display_name":"Federazione Medico Sportiva Italiana","ror":"https://ror.org/0301h4330","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210118979"]}],"countries":["IT"],"is_corresponding":true,"raw_author_name":"X. de la Torre","raw_affiliation_strings":["Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy. Electronic address: xavier.delatorre@fmsi.it","Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy. Electronic address: xavier.delatorre@fmsi.it","institution_ids":["https://openalex.org/I4210118979"]},{"raw_affiliation_string":"Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy","institution_ids":["https://openalex.org/I4210118979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080215230","display_name":"Dayamin Mart\u00ednez Brito","orcid":"https://orcid.org/0000-0002-7066-4916","observed_orcids":["https://orcid.org/0000-0002-7066-4916"]},"institutions":[{"id":"https://openalex.org/I4210118979","display_name":"Federazione Medico Sportiva Italiana","ror":"https://ror.org/0301h4330","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210118979"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"D. Martinez Brito","raw_affiliation_strings":["Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy","institution_ids":["https://openalex.org/I4210118979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007337965","display_name":"Cristiana Colamonici","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118979","display_name":"Federazione Medico Sportiva Italiana","ror":"https://ror.org/0301h4330","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210118979"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"C. Colamonici","raw_affiliation_strings":["Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy","institution_ids":["https://openalex.org/I4210118979"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082603586","display_name":"Maria Kristina Parr","orcid":"https://orcid.org/0000-0001-7407-8300","observed_orcids":["https://orcid.org/0000-0001-7407-8300"]},"institutions":[{"id":"https://openalex.org/I75951250","display_name":"Freie Universit\u00e4t Berlin","ror":"https://ror.org/046ak2485","country_code":"DE","type":"education","lineage":["https://openalex.org/I75951250"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"M.K. Parr","raw_affiliation_strings":["Freie Universit\u00e4t Berlin, Institute of Pharmacy, K\u00f6nigin-Luise-Str. 2+4, 14195 Berlin, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7407-8300","affiliations":[{"raw_affiliation_string":"Freie Universit\u00e4t Berlin, Institute of Pharmacy, K\u00f6nigin-Luise-Str. 2+4, 14195 Berlin, Germany","institution_ids":["https://openalex.org/I75951250"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081994437","display_name":"Francesco Botr\u00e8","orcid":"https://orcid.org/0000-0001-5296-8126","observed_orcids":["https://orcid.org/0000-0001-5296-8126"]},"institutions":[{"id":"https://openalex.org/I4210118979","display_name":"Federazione Medico Sportiva Italiana","ror":"https://ror.org/0301h4330","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210118979"]},{"id":"https://openalex.org/I861853513","display_name":"Sapienza University of Rome","ror":"https://ror.org/02be6w209","country_code":"IT","type":"education","lineage":["https://openalex.org/I861853513"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"F. Botr\u00e8","raw_affiliation_strings":["Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy; Department of Experimental Medicine, \"Sapienza\" University of Rome, Viale Regina Elena, 291, 00161 Roma, Italy","Department of Experimental Medicine, \"Sapienza\" University of Rome, Viale Regina Elena, 291, 00161 Roma, Italy","Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy"],"raw_orcid":"https://orcid.org/0000-0001-5296-8126","affiliations":[{"raw_affiliation_string":"Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy; Department of Experimental Medicine, \"Sapienza\" University of Rome, Viale Regina Elena, 291, 00161 Roma, Italy","institution_ids":["https://openalex.org/I4210118979","https://openalex.org/I861853513"]},{"raw_affiliation_string":"Department of Experimental Medicine, \"Sapienza\" University of Rome, Viale Regina Elena, 291, 00161 Roma, Italy","institution_ids":["https://openalex.org/I861853513"]},{"raw_affiliation_string":"Laboratorio Antidoping FMSI, Largo Onesti 1, 00197 Rome, Italy","institution_ids":["https://openalex.org/I4210118979"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5025398873"],"corresponding_institution_ids":["https://openalex.org/I4210118979"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":1.2383,"has_fulltext":true,"cited_by_count":8,"citation_normalized_percentile":{"value":0.83903279,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"146","issue":null,"first_page":"34","last_page":"42"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12700","display_name":"Doping in Sports","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},"topics":[{"id":"https://openalex.org/T12700","display_name":"Doping in Sports","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/3312","display_name":"Sociology and Political Science"},"field":{"id":"https://openalex.org/fields/33","display_name":"Social Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T13338","display_name":"Pharmacological Effects and Assays","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10800","display_name":"Forensic Toxicology and Drug Analysis","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/formestane","display_name":"formestane","score":0.9990000128746033},{"id":"https://openalex.org/keywords/aromatase-inhibitors","display_name":"aromatase inhibitors","score":0.7919999957084656},{"id":"https://openalex.org/keywords/urinary-biomarkers","display_name":"urinary biomarkers","score":0.7179999947547913},{"id":"https://openalex.org/keywords/metabolic-ratio","display_name":"metabolic ratio","score":0.7480000257492065},{"id":"https://openalex.org/keywords/transdermal-administration","display_name":"transdermal administration","score":0.9240000247955322},{"id":"https://openalex.org/keywords/oral-administration","display_name":"oral administration","score":0.9470000267028809},{"id":"https://openalex.org/keywords/isotope-ratio-mass-spectrometry","display_name":"isotope ratio mass spectrometry","score":0.7490000128746033},{"id":"https://openalex.org/keywords/doping-control","display_name":"doping control","score":0.43799999356269836},{"id":"https://openalex.org/keywords/drug-metabolism","display_name":"drug metabolism","score":0.4440000057220459}],"concepts":[{"id":"https://openalex.org/C2777477808","wikidata":"https://www.wikidata.org/wiki/Q407595","display_name":"Metabolite","level":2,"score":0.6365631818771362},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5984045267105103},{"id":"https://openalex.org/C2780026642","wikidata":"https://www.wikidata.org/wiki/Q40924","display_name":"Urine","level":2,"score":0.5197555422782898},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.4139018654823303},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.24012598395347595},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.20957612991333008}],"mesh":[{"descriptor_ui":"D000284","descriptor_name":"Administration, Oral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000735","descriptor_name":"Androstenedione","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000735","descriptor_name":"Androstenedione","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D000735","descriptor_name":"Androstenedione","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D004300","descriptor_name":"Doping in Sports","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000652","qualifier_name":"urine","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.steroids.2019.03.005","doi":"https://doi.org/10.1016/j.steroids.2019.03.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.steroids.2019.03.005","pdf_url":"https://ars.els-cdn.com/content/image/1-s2.0-S0039128X1930056X-ga1_lrg.jpg","source":{"id":"https://openalex.org/S70286497","display_name":"Steroids","issn_l":"0039-128X","issn":["0039-128X","1878-5867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Steroids","raw_type":"journal-article"},{"id":"pmid:30904502","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30904502","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Steroids","raw_type":"Journal Article"},{"id":"pmh:oai:flore.unifi.it:2158/1418641","doi":null,"is_oa":false,"landing_page_url":"https://hdl.handle.net/2158/1418641","pdf_url":null,"source":{"id":"https://openalex.org/S4306402033","display_name":"Florence Research (University of Florence)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I45084792","host_organization_name":"University of Florence","host_organization_lineage":["https://openalex.org/I45084792"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.uniroma1.it:11573/1277608","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/11573/1277608","pdf_url":null,"source":{"id":"https://openalex.org/S4377196107","display_name":"IRIS Research product catalog (Sapienza University of Rome)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.steroids.2019.03.005","doi":"https://doi.org/10.1016/j.steroids.2019.03.005","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.steroids.2019.03.005","pdf_url":"https://ars.els-cdn.com/content/image/1-s2.0-S0039128X1930056X-ga1_lrg.jpg","source":{"id":"https://openalex.org/S70286497","display_name":"Steroids","issn_l":"0039-128X","issn":["0039-128X","1878-5867"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Steroids","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G6486772177","display_name":null,"funder_award_id":"14A34XD","funder_id":"https://openalex.org/F4320321049","funder_display_name":"World Anti-Doping Agency"}],"funders":[{"id":"https://openalex.org/F4320321049","display_name":"World Anti-Doping Agency","ror":"https://ror.org/00v3jqn19"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2923913614.pdf","grobid_xml":"https://content.openalex.org/works/W2923913614.grobid-xml"},"referenced_works_count":22,"referenced_works":["https://openalex.org/W1840445876","https://openalex.org/W1885627082","https://openalex.org/W1951512380","https://openalex.org/W1981979045","https://openalex.org/W1985696642","https://openalex.org/W1990718894","https://openalex.org/W2011894404","https://openalex.org/W2034766336","https://openalex.org/W2043359573","https://openalex.org/W2066249651","https://openalex.org/W2067243526","https://openalex.org/W2075656166","https://openalex.org/W2085665743","https://openalex.org/W2105916100","https://openalex.org/W2106983444","https://openalex.org/W2140385224","https://openalex.org/W2148098219","https://openalex.org/W2149815192","https://openalex.org/W2170643981","https://openalex.org/W2767891136","https://openalex.org/W2769101301","https://openalex.org/W6638841816"],"related_works":["https://openalex.org/W1885627082","https://openalex.org/W6991074759","https://openalex.org/W1951512380","https://openalex.org/W2287595552","https://openalex.org/W1650090113","https://openalex.org/W2034766336","https://openalex.org/W2800177484","https://openalex.org/W2161506791","https://openalex.org/W3082653379","https://openalex.org/W2065770628"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-04-01T00:00:00"}