{"id":"https://openalex.org/W2922345274","doi":"https://doi.org/10.3168/jds.2018-15515","title":"Integrative plasma proteomic and microRNA analysis of Jersey cattle in response to high-altitude hypoxia","display_name":"Integrative plasma proteomic and microRNA analysis of Jersey cattle in response to high-altitude hypoxia","publication_year":2019,"publication_date":"2019-03-15","ids":{"openalex":"https://openalex.org/W2922345274","doi":"https://doi.org/10.3168/jds.2018-15515","mag":"2922345274","pmid":"https://pubmed.ncbi.nlm.nih.gov/30879823"},"language":"en","primary_location":{"id":"doi:10.3168/jds.2018-15515","doi":"https://doi.org/10.3168/jds.2018-15515","is_oa":true,"landing_page_url":"https://doi.org/10.3168/jds.2018-15515","pdf_url":"http://www.journalofdairyscience.org/article/S0022030219302516/pdf","source":{"id":"https://openalex.org/S28349394","display_name":"Journal of Dairy Science","issn_l":"0022-0302","issn":["0022-0302","1525-3198","1529-9066"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dairy Science","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"http://www.journalofdairyscience.org/article/S0022030219302516/pdf","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5085243073","display_name":"Zhiwei Kong","orcid":"https://orcid.org/0000-0003-0404-6498","observed_orcids":["https://orcid.org/0000-0003-0404-6498","https://orcid.org/0009-0000-7473-200X"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107235","display_name":"Institute of Subtropical Agriculture","ror":"https://ror.org/01hh9ag93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"id":"https://openalex.org/I4210165038","display_name":"University of Chinese Academy of Sciences","ror":"https://ror.org/05qbk4x57","country_code":"CN","type":"education","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiwei Kong","raw_affiliation_strings":["CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; University of the Chinese Academy of Sciences, Beijing 100049, China","CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","University of the Chinese Academy of Sciences, Beijing 100049, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; University of the Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235","https://openalex.org/I4210165038"]},{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"raw_affiliation_string":"University of the Chinese Academy of Sciences, Beijing 100049, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210165038"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005319291","display_name":"Chuanshe Zhou","orcid":"https://orcid.org/0000-0001-8609-7402","observed_orcids":["https://orcid.org/0000-0001-8609-7402"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107235","display_name":"Institute of Subtropical Agriculture","ror":"https://ror.org/01hh9ag93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Chuanshe Zhou","raw_affiliation_strings":["CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China. Electronic address: zcs@isa.ac.cn","CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China. Electronic address: zcs@isa.ac.cn","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"raw_affiliation_string":"Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100365217","display_name":"\u0411\u0438\u043d \u041b\u0438","orcid":"https://orcid.org/0000-0002-8038-0140","observed_orcids":["https://orcid.org/0000-0002-8038-0140"]},"institutions":[{"id":"https://openalex.org/I4210113048","display_name":"Tibet Academy of Agricultural and Animal Husbandry Sciences","ror":"https://ror.org/024d3p373","country_code":"CN","type":"education","lineage":["https://openalex.org/I4210113048"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Bin Li","raw_affiliation_strings":["Institute of Animal Husbandry and Veterinary, Tibet Autonomous Regional Academy of Agricultural Sciences, State Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement, Lhasa, Tibet 850000, China. Electronic address: xukesuolibin@163.com","Institute of Animal Husbandry and Veterinary, Tibet Autonomous Regional Academy of Agricultural Sciences, State Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement, Lhasa, Tibet 850000, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Animal Husbandry and Veterinary, Tibet Autonomous Regional Academy of Agricultural Sciences, State Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement, Lhasa, Tibet 850000, China. Electronic address: xukesuolibin@163.com","institution_ids":["https://openalex.org/I4210113048"]},{"raw_affiliation_string":"Institute of Animal Husbandry and Veterinary, Tibet Autonomous Regional Academy of Agricultural Sciences, State Key Laboratory of Hulless Barley and Yak Germplasm Resources and Genetic Improvement, Lhasa, Tibet 850000, China","institution_ids":["https://openalex.org/I4210113048"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056994259","display_name":"Jinzhen Jiao","orcid":"https://orcid.org/0000-0002-6064-2270","observed_orcids":["https://orcid.org/0000-0002-6064-2270"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107235","display_name":"Institute of Subtropical Agriculture","ror":"https://ror.org/01hh9ag93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jinzhen Jiao","raw_affiliation_strings":["CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China","CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"raw_affiliation_string":"Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031520395","display_name":"Liang Chen","orcid":"https://orcid.org/0000-0001-6644-477X","observed_orcids":["https://orcid.org/0000-0001-6644-477X"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107235","display_name":"Institute of Subtropical Agriculture","ror":"https://ror.org/01hh9ag93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"id":"https://openalex.org/I52180223","display_name":"Hunan Agricultural University","ror":"https://ror.org/01dzed356","country_code":"CN","type":"education","lineage":["https://openalex.org/I52180223"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Liang Chen","raw_affiliation_strings":["CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China","CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235","https://openalex.org/I52180223"]},{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"raw_affiliation_string":"College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China","institution_ids":["https://openalex.org/I52180223"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007868692","display_name":"Ao Ren","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107235","display_name":"Institute of Subtropical Agriculture","ror":"https://ror.org/01hh9ag93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"id":"https://openalex.org/I52180223","display_name":"Hunan Agricultural University","ror":"https://ror.org/01dzed356","country_code":"CN","type":"education","lineage":["https://openalex.org/I52180223"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ao Ren","raw_affiliation_strings":["CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China","CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235","https://openalex.org/I52180223"]},{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"raw_affiliation_string":"College of Animal Science and Technology, Hunan Agricultural University, Changsha, Hunan 410128, China","institution_ids":["https://openalex.org/I52180223"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hongdong Jie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107235","display_name":"Institute of Subtropical Agriculture","ror":"https://ror.org/01hh9ag93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongdong Jie","raw_affiliation_strings":["CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5059755224","display_name":"Zhiliang Tan","orcid":"https://orcid.org/0000-0002-7483-1478","observed_orcids":["https://orcid.org/0000-0002-7483-1478"]},"institutions":[{"id":"https://openalex.org/I19820366","display_name":"Chinese Academy of Sciences","ror":"https://ror.org/034t30j35","country_code":"CN","type":"government","lineage":["https://openalex.org/I19820366"]},{"id":"https://openalex.org/I4210107235","display_name":"Institute of Subtropical Agriculture","ror":"https://ror.org/01hh9ag93","country_code":"CN","type":"facility","lineage":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhiliang Tan","raw_affiliation_strings":["CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China","CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China; Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"raw_affiliation_string":"CAS Key Laboratory for Agro-Ecological Processes in Subtropical Region, National Engineering Laboratory for Pollution Control and Waste Utilization in Livestock and Poultry Production, South-Central Experimental Station of Animal Nutrition and Feed Science in Ministry of Agriculture, Hunan Provincial Engineering Research Center for Healthy Livestock and Poultry Production, Institute of Subtropical Agriculture, The Chinese Academy of Sciences, Changsha, Hunan 410125, China","institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235"]},{"raw_affiliation_string":"Hunan Co-Innovation Center of Safety Animal Production (CICSAP), Changsha, Hunan 410128, China","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":5,"corresponding_author_ids":["https://openalex.org/A5005319291","https://openalex.org/A5100365217"],"corresponding_institution_ids":["https://openalex.org/I19820366","https://openalex.org/I4210107235","https://openalex.org/I4210113048"],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":2.6538,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.88878607,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"102","issue":"5","first_page":"4606","last_page":"4618"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11968","display_name":"High Altitude and Hypoxia","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12365","display_name":"Effects of Environmental Stressors on Livestock","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1103","display_name":"Animal Science and Zoology"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10594","display_name":"Genetic and phenotypic traits in livestock","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/high-altitude-hypoxia","display_name":"high-altitude hypoxia","score":0.949999988079071},{"id":"https://openalex.org/keywords/jersey-cattle","display_name":"Jersey cattle","score":0.9940000176429749},{"id":"https://openalex.org/keywords/plasma-proteome","display_name":"plasma proteome","score":0.8640000224113464},{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.8159999847412109},{"id":"https://openalex.org/keywords/hypoxia-adaptation","display_name":"hypoxia adaptation","score":0.7519999742507935},{"id":"https://openalex.org/keywords/acute-phase-response","display_name":"acute phase response","score":0.8289999961853027},{"id":"https://openalex.org/keywords/complement-system","display_name":"complement system","score":0.9610000252723694},{"id":"https://openalex.org/keywords/blood-coagulation-system","display_name":"coagulation system","score":0.9800000190734863},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.6909999847412109},{"id":"https://openalex.org/keywords/itraq-proteomics","display_name":"iTRAQ quantitative proteomics","score":0.5889999866485596}],"concepts":[{"id":"https://openalex.org/C7836513","wikidata":"https://www.wikidata.org/wiki/Q1641506","display_name":"Hypoxia (environmental)","level":3,"score":0.8192851543426514},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6911550760269165},{"id":"https://openalex.org/C8240015","wikidata":"https://www.wikidata.org/wiki/Q918226","display_name":"Effects of high altitude on humans","level":2,"score":0.5577716827392578},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4244523048400879},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.39136233925819397},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.24056494235992432},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23198798298835754},{"id":"https://openalex.org/C540031477","wikidata":"https://www.wikidata.org/wiki/Q629","display_name":"Oxygen","level":2,"score":0.13123679161071777},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.12513217329978943},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.10141327977180481},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000071518","descriptor_name":"Liver X Receptors","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000531","descriptor_name":"Altitude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000532","descriptor_name":"Altitude Sickness","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D000532","descriptor_name":"Altitude Sickness","qualifier_ui":"Q000662","qualifier_name":"veterinary","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002417","descriptor_name":"Cattle","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002681","descriptor_name":"China","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003165","descriptor_name":"Complement System Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005786","descriptor_name":"Gene Expression Regulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D018609","descriptor_name":"Tibet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D040901","descriptor_name":"Proteomics","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D047488","descriptor_name":"Retinoid X Receptors","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.3168/jds.2018-15515","doi":"https://doi.org/10.3168/jds.2018-15515","is_oa":true,"landing_page_url":"https://doi.org/10.3168/jds.2018-15515","pdf_url":"http://www.journalofdairyscience.org/article/S0022030219302516/pdf","source":{"id":"https://openalex.org/S28349394","display_name":"Journal of Dairy Science","issn_l":"0022-0302","issn":["0022-0302","1525-3198","1529-9066"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dairy Science","raw_type":"journal-article"},{"id":"pmid:30879823","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30879823","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of dairy science","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.3168/jds.2018-15515","doi":"https://doi.org/10.3168/jds.2018-15515","is_oa":true,"landing_page_url":"https://doi.org/10.3168/jds.2018-15515","pdf_url":"http://www.journalofdairyscience.org/article/S0022030219302516/pdf","source":{"id":"https://openalex.org/S28349394","display_name":"Journal of Dairy Science","issn_l":"0022-0302","issn":["0022-0302","1525-3198","1529-9066"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","jufo-3","ki-jl-1","medline","norway-2","oarl","poland-200","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Dairy Science","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1224875130","display_name":null,"funder_award_id":"2017JJ1028","funder_id":"https://openalex.org/F4320321471","funder_display_name":"Hunan Provincial Science and Technology Department"},{"id":"https://openalex.org/G221732224","display_name":null,"funder_award_id":"31772632","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2582655391","display_name":null,"funder_award_id":"2013TF3006","funder_id":"https://openalex.org/F4320321471","funder_display_name":"Hunan Provincial Science and Technology Department"},{"id":"https://openalex.org/G2899223267","display_name":null,"funder_award_id":"31372342","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4074244150","display_name":null,"funder_award_id":"No. 31772632, 31372342","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G4832661382","display_name":null,"funder_award_id":"2017NK1020","funder_id":"https://openalex.org/F4320321471","funder_display_name":"Hunan Provincial Science and Technology Department"},{"id":"https://openalex.org/G5790864320","display_name":null,"funder_award_id":"2017YFD0500500","funder_id":"https://openalex.org/F4320321540","funder_display_name":"Ministry of Science and Technology of the People's Republic of China"},{"id":"https://openalex.org/G6188734657","display_name":null,"funder_award_id":"2017QNCXTD_ZCS","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G7309190866","display_name":null,"funder_award_id":"2018YFD0501604","funder_id":"https://openalex.org/F4320321540","funder_display_name":"Ministry of Science and Technology of the People's Republic of China"},{"id":"https://openalex.org/G8820805810","display_name":null,"funder_award_id":"31772632, 31372342","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320321471","display_name":"Hunan Provincial Science and Technology Department","ror":"https://ror.org/04qgr7x96"},{"id":"https://openalex.org/F4320321540","display_name":"Ministry of Science and Technology of the People's Republic of China","ror":"https://ror.org/027s68j25"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2922345274.pdf","grobid_xml":"https://content.openalex.org/works/W2922345274.grobid-xml"},"referenced_works_count":68,"referenced_works":["https://openalex.org/W199757098","https://openalex.org/W758436661","https://openalex.org/W809655803","https://openalex.org/W830491774","https://openalex.org/W886035700","https://openalex.org/W1541723851","https://openalex.org/W1559617701","https://openalex.org/W1653041927","https://openalex.org/W1788527284","https://openalex.org/W1966584984","https://openalex.org/W1968775339","https://openalex.org/W1971748489","https://openalex.org/W1979674730","https://openalex.org/W1986415793","https://openalex.org/W1988163167","https://openalex.org/W1990312329","https://openalex.org/W1993223367","https://openalex.org/W1996251543","https://openalex.org/W1999623479","https://openalex.org/W2005044790","https://openalex.org/W2014869583","https://openalex.org/W2019102807","https://openalex.org/W2021539595","https://openalex.org/W2022625680","https://openalex.org/W2026724360","https://openalex.org/W2027719255","https://openalex.org/W2028796402","https://openalex.org/W2036209716","https://openalex.org/W2038520549","https://openalex.org/W2047529648","https://openalex.org/W2057086747","https://openalex.org/W2058205407","https://openalex.org/W2060013333","https://openalex.org/W2063123633","https://openalex.org/W2065566217","https://openalex.org/W2065911556","https://openalex.org/W2075183916","https://openalex.org/W2079294041","https://openalex.org/W2103604860","https://openalex.org/W2114104545","https://openalex.org/W2115445409","https://openalex.org/W2117218533","https://openalex.org/W2127133949","https://openalex.org/W2128507820","https://openalex.org/W2130169308","https://openalex.org/W2130610708","https://openalex.org/W2135104512","https://openalex.org/W2137881107","https://openalex.org/W2140509306","https://openalex.org/W2141860697","https://openalex.org/W2142499877","https://openalex.org/W2151355004","https://openalex.org/W2153338081","https://openalex.org/W2162143298","https://openalex.org/W2163323666","https://openalex.org/W2166216995","https://openalex.org/W2167937185","https://openalex.org/W2169064602","https://openalex.org/W2169437650","https://openalex.org/W2169965967","https://openalex.org/W2352821981","https://openalex.org/W2360500042","https://openalex.org/W2602662490","https://openalex.org/W2763521860","https://openalex.org/W2806634376","https://openalex.org/W2883715294","https://openalex.org/W4230088158","https://openalex.org/W4285719527"],"related_works":["https://openalex.org/W2954592909","https://openalex.org/W2933812160","https://openalex.org/W2969398587","https://openalex.org/W2085369144","https://openalex.org/W2612885122","https://openalex.org/W2094704686","https://openalex.org/W2317315624","https://openalex.org/W2912505616","https://openalex.org/W2411282866","https://openalex.org/W4285245642"],"abstract_inverted_index":{"Blood":[0],"has":[1],"been":[2],"widely":[3],"collected":[4],"and":[5,9,14,21,90,95,106,122,139,159,186,204,241,275,278],"analyzed":[6],"for":[7,88,137],"diagnosing":[8],"monitoring":[10],"diseases":[11],"in":[12,35,48,102,116,125,173],"humans":[13],"animals;":[15],"a":[16],"range":[17],"of":[18,52,109,142,184,209,264],"plasma":[19,104],"proteins":[20,150,198],"peptide":[22],"can":[23,43],"be":[24],"used":[25,67],"as":[26,39],"biomarkers":[27],"to":[28,45,99,113,255,259],"describe":[29],"pathological":[30],"or":[31],"physiological":[32],"status.":[33],"Changes":[34],"the":[36,49,55,103,174,179,191,269],"environment":[37],"such":[38],"high-altitude":[40],"hypoxia":[41],"(HAH)":[42],"lead":[44],"adaptive":[46],"changes":[47],"blood":[50],"system":[51,237,243,277],"mammals.":[53],"However,":[54],"adaptation":[56],"mechanism":[57],"induced":[58],"by":[59,267],"HAH":[60,114,256],"remains":[61],"unclear.":[62],"In":[63,145],"this":[64],"study,":[65],"we":[66],"12":[68],"multiparous":[69],"Jersey":[70,110,252],"cattle":[71,111,253],"(400":[72],"\u00b1":[73],"35":[74],"kg,":[75],"average":[76],"3":[77],"yr":[78],"old,":[79],"dry":[80],"period).":[81],"We":[82],"applied":[83],"an":[84],"iTRAQ":[85],"(isobaric":[86],"tags":[87],"relative":[89],"absolute":[91],"quantitation)":[92],"proteomics":[93],"approach":[94],"microRNA":[96],"(miRNA)":[97],"microarray":[98],"explore":[100],"differences":[101],"proteomic":[105,133,185],"miRNA":[107,143,187],"profiles":[108,188],"exposed":[112,254],"conditions":[115,124],"Nyingchi,":[117],"Tibet":[118],"(altitude":[119,128],"3,000":[120],"m)":[121],"HAH-free":[123,180],"Shenyang,":[126],"China":[127],"50":[129],"m).":[130],"Such":[131],"quantitative":[132],"strategies":[134],"are":[135],"suitable":[136],"accurate":[138],"comprehensive":[140],"prediction":[141],"targets.":[144],"total,":[146],"264":[147],"differentially":[148,196],"expressed":[149,197],"(127":[151],"upregulated,":[152,164],"fold-change":[153,157,165,169],">1.2;":[154],"137":[155],"downregulated,":[156,168],"<0.8)":[158],"47":[160],"differential":[161],"miRNAs":[162],"(25":[163],">2;":[166],"22":[167],"<0.5)":[170],"were":[171,199,215],"observed":[172],"HAH-stressed":[175],"group":[176],"compared":[177],"with":[178,195,217],"group.":[181],"Integrative":[182,207],"analysis":[183,208],"demonstrated":[189],"that":[190,213,251,260],"biological":[192],"processes":[193],"associated":[194,216],"immune":[200],"response,":[201,272],"complement":[202,242,276],"system,":[203,274],"conjugation":[205],"system.":[206],"canonical":[210],"pathways":[211],"showed":[212],"most":[214],"acute":[218,270],"phase":[219,271],"response":[220],"signaling":[221],"(z-score":[222,233,238,244],"=":[223,234,239,245],"-0.125),":[224],"liver":[225],"X":[226,228],"receptor/retinoid":[227],"receptor":[229],"(LXR/RXR)":[230],"activation":[231],"pathway":[232],"1.134),":[235],"coagulation":[236,273],"-0.943),":[240],"-0.632).":[246],"The":[247],"current":[248],"results":[249],"indicated":[250],"could":[257],"adapt":[258],"condition":[261],"through":[262],"regulation":[263],"inflammatory":[265],"homeostasis":[266],"inhibiting":[268],"promoting":[279],"LXR/RXR":[280],"activation.":[281]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-13T13:42:25.865203","created_date":"2019-03-22T00:00:00"}
