{"id":"https://openalex.org/W2922273689","doi":"https://doi.org/10.1038/s41422-019-0155-6","title":"LSECtin on tumor-associated macrophages enhances breast cancer stemness via interaction with its receptor BTN3A3","display_name":"LSECtin on tumor-associated macrophages enhances breast cancer stemness via interaction with its receptor BTN3A3","publication_year":2019,"publication_date":"2019-03-11","ids":{"openalex":"https://openalex.org/W2922273689","doi":"https://doi.org/10.1038/s41422-019-0155-6","mag":"2922273689","pmid":"https://pubmed.ncbi.nlm.nih.gov/30858559","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6796923"},"language":"en","primary_location":{"id":"doi:10.1038/s41422-019-0155-6","doi":"https://doi.org/10.1038/s41422-019-0155-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41422-019-0155-6","pdf_url":"https://www.nature.com/articles/s41422-019-0155-6.pdf","source":{"id":"https://openalex.org/S128296271","display_name":"Cell Research","issn_l":"1001-0602","issn":["1001-0602","1748-7838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.nature.com/articles/s41422-019-0155-6.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101982840","display_name":"Di Liu","orcid":"https://orcid.org/0000-0002-8352-5659","observed_orcids":["https://orcid.org/0000-0002-8352-5659"]},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Di Liu","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045890071","display_name":"Qian Lu","orcid":"https://orcid.org/0000-0001-6395-693X","observed_orcids":["https://orcid.org/0000-0001-6395-693X"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]},{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Qian Lu","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui Province, China","State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui Province, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, China","institution_ids":["https://openalex.org/I197869895"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100365503","display_name":"Xing Wang","orcid":"https://orcid.org/0000-0002-6080-4540","observed_orcids":["https://orcid.org/0000-0002-6080-4540","https://orcid.org/0000-0003-3388-9929"]},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xing Wang","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100384777","display_name":"Jun Wang","orcid":"https://orcid.org/0000-0002-6346-2929","observed_orcids":["https://orcid.org/0000-0002-6346-2929"]},"institutions":[{"id":"https://openalex.org/I2802730090","display_name":"Yale Cancer Center","ror":"https://ror.org/03j7sze86","country_code":"US","type":"facility","lineage":["https://openalex.org/I2802730090","https://openalex.org/I4210117499","https://openalex.org/I4210165192"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jun Wang","raw_affiliation_strings":["Department of immunobiology and Yale Cancer Center, Yale School of Medicine, New Haven, CT, 06511, USA","Department of immunobiology and Yale Cancer Center, Yale School of Medicine, New Haven, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of immunobiology and Yale Cancer Center, Yale School of Medicine, New Haven, CT, 06511, USA","institution_ids":["https://openalex.org/I2802730090","https://openalex.org/I32971472"]},{"raw_affiliation_string":"Department of immunobiology and Yale Cancer Center, Yale School of Medicine, New Haven, USA","institution_ids":["https://openalex.org/I2802730090","https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100737580","display_name":"Ning L\u00fc","orcid":"https://orcid.org/0000-0002-3826-8673","observed_orcids":["https://orcid.org/0000-0002-3826-8673"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ning Lu","raw_affiliation_strings":["Department of Orthopedics, PLA General Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Orthopedics, PLA General Hospital, Beijing, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076149259","display_name":"Zefei Jiang","orcid":"https://orcid.org/0000-0002-4295-0173","observed_orcids":["https://orcid.org/0000-0002-4295-0173"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zefei Jiang","raw_affiliation_strings":["Department of Breast Cancer, The Fifth Medical Center of PLA General Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast Cancer, The Fifth Medical Center of PLA General Hospital, Beijing, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103208888","display_name":"Xiaopeng Hao","orcid":"https://orcid.org/0000-0002-0736-8962","observed_orcids":["https://orcid.org/0000-0002-0736-8962"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Xiaopeng Hao","raw_affiliation_strings":["Department of Breast Cancer, The Fifth Medical Center of PLA General Hospital, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast Cancer, The Fifth Medical Center of PLA General Hospital, Beijing, China","institution_ids":["https://openalex.org/I2802939634"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100356247","display_name":"Jianbin Li","orcid":"https://orcid.org/0000-0001-7813-0452","observed_orcids":["https://orcid.org/0000-0001-7813-0452"]},"institutions":[{"id":"https://openalex.org/I2802939634","display_name":"Chinese PLA General Hospital","ror":"https://ror.org/04gw3ra78","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I2802939634"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jianbin Li","raw_affiliation_strings":["Department of Breast Cancer, The Fifth Medical Center of PLA General Hospital, Beijing, China","Department of Medical Molecular Biology, Beijing Institute of Biotechnology, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Breast Cancer, The Fifth Medical Center of PLA General Hospital, Beijing, China","institution_ids":["https://openalex.org/I2802939634"]},{"raw_affiliation_string":"Department of Medical Molecular Biology, Beijing Institute of Biotechnology, Beijing, China","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100375121","display_name":"Jing Liu","orcid":"https://orcid.org/0000-0003-3467-9392","observed_orcids":["https://orcid.org/0000-0003-3467-9392"]},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jing Liu","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053672456","display_name":"Pengbo Cao","orcid":"https://orcid.org/0000-0002-7820-114X","observed_orcids":["https://orcid.org/0000-0002-7820-114X"]},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Pengbo Cao","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Guilin Peng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guilin Peng","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025454919","display_name":"Yuandong Tao","orcid":"https://orcid.org/0000-0001-5677-103X","observed_orcids":["https://orcid.org/0000-0001-5677-103X"]},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yuandong Tao","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033485241","display_name":"Dianyuan Zhao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Dianyuan Zhao","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091436402","display_name":"Fuchu He","orcid":"https://orcid.org/0000-0002-8571-2351","observed_orcids":["https://orcid.org/0000-0002-8571-2351"]},"institutions":[{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Fuchu He","raw_affiliation_strings":["State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China. hefc@nic.bmi.ac.cn","State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China. hefc@nic.bmi.ac.cn","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]},{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100329329","display_name":"Tang Li","orcid":"https://orcid.org/0000-0001-6622-9471","observed_orcids":["https://orcid.org/0000-0001-6622-9471"]},"institutions":[{"id":"https://openalex.org/I197869895","display_name":"Anhui Medical University","ror":"https://ror.org/03xb04968","country_code":"CN","type":"education","lineage":["https://openalex.org/I197869895"]},{"id":"https://openalex.org/I4210149540","display_name":"Beijing Proteome Research Center","ror":"https://ror.org/05pp5b412","country_code":"CN","type":"facility","lineage":["https://openalex.org/I4210149540"]},{"id":"https://openalex.org/I4391768116","display_name":"State Key Laboratory of Proteomics","ror":"https://ror.org/019bev041","country_code":"CN","type":"facility","lineage":["https://openalex.org/I2802541053","https://openalex.org/I4391768116"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Li Tang","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui Province, China. tangli731@163.com","State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China. tangli731@163.com","Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, China","State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, Anhui Province, China. tangli731@163.com","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China. tangli731@163.com","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Anhui Medical University, Hefei, China","institution_ids":["https://openalex.org/I197869895"]},{"raw_affiliation_string":"State Key Laboratory of Proteomics, Beijing Proteome Research Center, National Center for Protein Sciences\u00b7Beijing, Beijing Institute of Lifeomics, Beijing, China","institution_ids":["https://openalex.org/I4210149540","https://openalex.org/I4391768116"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5091436402","https://openalex.org/A5100329329"],"corresponding_institution_ids":["https://openalex.org/I197869895","https://openalex.org/I4210149540","https://openalex.org/I4391768116"],"apc_list":{"value":4390,"currency":"USD","value_usd":4390},"apc_paid":null,"fwci":2.8481,"has_fulltext":true,"cited_by_count":70,"citation_normalized_percentile":{"value":0.91356577,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"29","issue":"5","first_page":"365","last_page":"378"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.8173999786376953,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer","score":0.8173999786376953,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis","score":0.17479999363422394,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research","score":0.0008999999845400453,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/lsectin","display_name":"LSECtin","score":0.9990000128746033},{"id":"https://openalex.org/keywords/btn3a3","display_name":"BTN3A3","score":0.9829999804496765},{"id":"https://openalex.org/keywords/tumor-associated-macrophages","display_name":"tumor-associated macrophages","score":0.9860000014305115},{"id":"https://openalex.org/keywords/breast-cancer-stem-cells","display_name":"breast cancer stem cells","score":0.8429999947547913},{"id":"https://openalex.org/keywords/cancer-stemness","display_name":"cancer stemness","score":0.8309999704360962},{"id":"https://openalex.org/keywords/juxtacrine-signaling","display_name":"juxtacrine signaling","score":0.9900000095367432},{"id":"https://openalex.org/keywords/cancer-stem-cell-niche","display_name":"cancer stem cell niche","score":0.7960000038146973},{"id":"https://openalex.org/keywords/macrophage-depletion","display_name":"macrophage depletion","score":0.6669999957084656}],"concepts":[{"id":"https://openalex.org/C64863464","wikidata":"https://www.wikidata.org/wiki/Q3190616","display_name":"Juxtacrine signalling","level":4,"score":0.8847514390945435},{"id":"https://openalex.org/C55427017","wikidata":"https://www.wikidata.org/wiki/Q1638475","display_name":"Cancer stem cell","level":3,"score":0.6843441724777222},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6100047826766968},{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.573783814907074},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4668978154659271},{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.4654366075992584},{"id":"https://openalex.org/C10116572","wikidata":"https://www.wikidata.org/wiki/Q18033097","display_name":"LGR5","level":4,"score":0.450814813375473},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4414086937904358},{"id":"https://openalex.org/C119056186","wikidata":"https://www.wikidata.org/wiki/Q1431332","display_name":"Gene silencing","level":3,"score":0.4230506420135498},{"id":"https://openalex.org/C28328180","wikidata":"https://www.wikidata.org/wiki/Q48196","display_name":"Stem cell","level":2,"score":0.39907383918762207},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3976539969444275},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.33177992701530457},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3053683042526245},{"id":"https://openalex.org/C128240485","wikidata":"https://www.wikidata.org/wiki/Q786998","display_name":"Autocrine signalling","level":3,"score":0.23425626754760742},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2336243987083435},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.21268808841705322},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000071797","descriptor_name":"Butyrophilins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D000071797","descriptor_name":"Butyrophilins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D000071797","descriptor_name":"Butyrophilins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D000097382","descriptor_name":"CD68 Molecule","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008819","descriptor_name":"Mice, Nude","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014411","descriptor_name":"Neoplastic Stem Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015214","descriptor_name":"Antigens, Differentiation, Myelomonocytic","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D015398","descriptor_name":"Signal Transduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015703","descriptor_name":"Antigens, CD","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D037181","descriptor_name":"Lectins, C-Type","qualifier_ui":"Q000172","qualifier_name":"deficiency","is_major_topic":false},{"descriptor_ui":"D037181","descriptor_name":"Lectins, C-Type","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D037181","descriptor_name":"Lectins, C-Type","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D045744","descriptor_name":"Cell Line, Tumor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049109","descriptor_name":"Cell Proliferation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1038/s41422-019-0155-6","doi":"https://doi.org/10.1038/s41422-019-0155-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41422-019-0155-6","pdf_url":"https://www.nature.com/articles/s41422-019-0155-6.pdf","source":{"id":"https://openalex.org/S128296271","display_name":"Cell Research","issn_l":"1001-0602","issn":["1001-0602","1748-7838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Research","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6796923","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6796923","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Res","raw_type":"Text"},{"id":"pmid:30858559","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30858559","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell research","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1038/s41422-019-0155-6","doi":"https://doi.org/10.1038/s41422-019-0155-6","is_oa":true,"landing_page_url":"https://doi.org/10.1038/s41422-019-0155-6","pdf_url":"https://www.nature.com/articles/s41422-019-0155-6.pdf","source":{"id":"https://openalex.org/S128296271","display_name":"Cell Research","issn_l":"1001-0602","issn":["1001-0602","1748-7838"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","doyens","jufo-2","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cell Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4509317583","display_name":null,"funder_award_id":"2014CBA02000","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"},{"id":"https://openalex.org/G8948442854","display_name":null,"funder_award_id":"2018YFA0507500","funder_id":"https://openalex.org/F4320335777","funder_display_name":"National Key Research and Development Program of China"}],"funders":[{"id":"https://openalex.org/F4320321543","display_name":"China Postdoctoral Science Foundation","ror":"https://ror.org/0426zh255"},{"id":"https://openalex.org/F4320335777","display_name":"National Key Research and Development Program of China","ror":null}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2922273689.pdf","grobid_xml":"https://content.openalex.org/works/W2922273689.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W1969057487","https://openalex.org/W1984413324","https://openalex.org/W1995483790","https://openalex.org/W2000272838","https://openalex.org/W2002147164","https://openalex.org/W2007196889","https://openalex.org/W2012034410","https://openalex.org/W2018372624","https://openalex.org/W2021296394","https://openalex.org/W2052467200","https://openalex.org/W2058648826","https://openalex.org/W2065379975","https://openalex.org/W2068563163","https://openalex.org/W2069264184","https://openalex.org/W2071123870","https://openalex.org/W2071732560","https://openalex.org/W2073759231","https://openalex.org/W2093027168","https://openalex.org/W2114505219","https://openalex.org/W2118197531","https://openalex.org/W2127617517","https://openalex.org/W2134205085","https://openalex.org/W2136807515","https://openalex.org/W2141531733","https://openalex.org/W2153086428","https://openalex.org/W2162166699","https://openalex.org/W2164035788","https://openalex.org/W2169729679","https://openalex.org/W2170567846","https://openalex.org/W2253691911","https://openalex.org/W2329768139","https://openalex.org/W2548602591","https://openalex.org/W2582686270","https://openalex.org/W2594268434","https://openalex.org/W2803157002","https://openalex.org/W4301159569"],"related_works":["https://openalex.org/W2943550506","https://openalex.org/W4220725890","https://openalex.org/W3130749184","https://openalex.org/W2810465257","https://openalex.org/W7081977454","https://openalex.org/W2087688974","https://openalex.org/W2018372624","https://openalex.org/W2401385317","https://openalex.org/W1596104070","https://openalex.org/W4283023108"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":7},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":9},{"year":2023,"cited_by_count":13},{"year":2022,"cited_by_count":15},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-03-22T00:00:00"}