{"id":"https://openalex.org/W2921228992","doi":"https://doi.org/10.1016/j.nutres.2019.03.004","title":"Dietary walnut altered gene expressions related to tumor growth, survival, and metastasis in breast cancer patients: a pilot clinical trial","display_name":"Dietary walnut altered gene expressions related to tumor growth, survival, and metastasis in breast cancer patients: a pilot clinical trial","publication_year":2019,"publication_date":"2019-03-10","ids":{"openalex":"https://openalex.org/W2921228992","doi":"https://doi.org/10.1016/j.nutres.2019.03.004","mag":"2921228992","pmid":"https://pubmed.ncbi.nlm.nih.gov/30979659","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6853029"},"language":"en","primary_location":{"id":"doi:10.1016/j.nutres.2019.03.004","doi":"https://doi.org/10.1016/j.nutres.2019.03.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.nutres.2019.03.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0271531718311904/pdf","source":{"id":"https://openalex.org/S123713480","display_name":"Nutrition Research","issn_l":"0271-5317","issn":["0271-5317","1879-0739"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition Research","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.sciencedirect.com/science/article/pii/S0271531718311904/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109922905","display_name":"W. Elaine Hardman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I88694374","display_name":"Marshall University","ror":"https://ror.org/02erqft81","country_code":"US","type":"education","lineage":["https://openalex.org/I88694374"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"W. Elaine Hardman","raw_affiliation_strings":["Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA. Electronic address: hardmanw@marshall.edu","Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA. Electronic address: hardmanw@marshall.edu","institution_ids":["https://openalex.org/I88694374"]},{"raw_affiliation_string":"Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA","institution_ids":["https://openalex.org/I88694374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025451447","display_name":"Donald A. Primerano","orcid":"https://orcid.org/0000-0002-2175-4472","observed_orcids":["https://orcid.org/0000-0002-2175-4472"]},"institutions":[{"id":"https://openalex.org/I88694374","display_name":"Marshall University","ror":"https://ror.org/02erqft81","country_code":"US","type":"education","lineage":["https://openalex.org/I88694374"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Donald A. Primerano","raw_affiliation_strings":["Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA. Electronic address: primeran@marshall.edu","Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA"],"raw_orcid":"https://orcid.org/0000-0002-2175-4472","affiliations":[{"raw_affiliation_string":"Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA. Electronic address: primeran@marshall.edu","institution_ids":["https://openalex.org/I88694374"]},{"raw_affiliation_string":"Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA","institution_ids":["https://openalex.org/I88694374"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5055554508","display_name":"Mary T. Legenza","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210136212","display_name":"Edwards Comprehensive Cancer Center","ror":"https://ror.org/03qrhd488","country_code":"US","type":"facility","lineage":["https://openalex.org/I2800305746","https://openalex.org/I4210136212","https://openalex.org/I88694374"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mary T. Legenza","raw_affiliation_strings":["Edwards Comprehensive Cancer Center, 1400 Hal Greer Dr, Huntington, WV 25701, USA. Electronic address: legenza@marshall.edu","Edwards Comprehensive Cancer Center, 1400 Hal Greer Dr, Huntington, WV 25701, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Edwards Comprehensive Cancer Center, 1400 Hal Greer Dr, Huntington, WV 25701, USA. Electronic address: legenza@marshall.edu","institution_ids":["https://openalex.org/I4210136212"]},{"raw_affiliation_string":"Edwards Comprehensive Cancer Center, 1400 Hal Greer Dr, Huntington, WV 25701, USA","institution_ids":["https://openalex.org/I4210136212"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110028495","display_name":"James Morgan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"James Morgan","raw_affiliation_strings":["St. Mary's Cancer Center, 2900 1st Ave, Huntington, WV 25702, USA. Electronic address: jhmorgan3@gmail.com","St. Mary's Cancer Center, 2900 1st Ave, Huntington, WV 25702, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"St. Mary's Cancer Center, 2900 1st Ave, Huntington, WV 25702, USA. Electronic address: jhmorgan3@gmail.com","institution_ids":[]},{"raw_affiliation_string":"St. Mary's Cancer Center, 2900 1st Ave, Huntington, WV 25702, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100659630","display_name":"Jun Fan","orcid":"https://orcid.org/0000-0002-5445-437X","observed_orcids":["https://orcid.org/0000-0002-5445-437X"]},"institutions":[{"id":"https://openalex.org/I88694374","display_name":"Marshall University","ror":"https://ror.org/02erqft81","country_code":"US","type":"education","lineage":["https://openalex.org/I88694374"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jun Fan","raw_affiliation_strings":["Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA. Electronic address: fanj@marshall.edu","Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA. Electronic address: fanj@marshall.edu","institution_ids":["https://openalex.org/I88694374"]},{"raw_affiliation_string":"Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA","institution_ids":["https://openalex.org/I88694374"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5016924282","display_name":"James Denvir","orcid":"https://orcid.org/0000-0001-8836-6653","observed_orcids":["https://orcid.org/0000-0001-8836-6653"]},"institutions":[{"id":"https://openalex.org/I88694374","display_name":"Marshall University","ror":"https://ror.org/02erqft81","country_code":"US","type":"education","lineage":["https://openalex.org/I88694374"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James Denvir","raw_affiliation_strings":["Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA. Electronic address: denvir@marshall.edu","Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA"],"raw_orcid":"https://orcid.org/0000-0001-8836-6653","affiliations":[{"raw_affiliation_string":"Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA. Electronic address: denvir@marshall.edu","institution_ids":["https://openalex.org/I88694374"]},{"raw_affiliation_string":"Joan C. Edwards School of Medicine, Marshall University, Department of Biomedical Sciences, 1600 Medical Center Dr, Huntington, WV 25701, USA","institution_ids":["https://openalex.org/I88694374"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5109922905"],"corresponding_institution_ids":["https://openalex.org/I88694374"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":3.5026,"has_fulltext":true,"cited_by_count":32,"citation_normalized_percentile":{"value":0.91744627,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"66","issue":null,"first_page":"82","last_page":"94"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12314","display_name":"Nuts composition and effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12314","display_name":"Nuts composition and effects","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10866","display_name":"Nutritional Studies and Diet","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/walnut-consumption","display_name":"walnut consumption","score":0.9649999737739563},{"id":"https://openalex.org/keywords/breast-cancer","display_name":"breast cancer","score":0.9539999961853027},{"id":"https://openalex.org/keywords/gene-expression-profiling","display_name":"gene expression profiling","score":0.7599999904632568},{"id":"https://openalex.org/keywords/tumor-growth","display_name":"tumor growth","score":0.8040000200271606},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.6539999842643738},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.7739999890327454},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.8920000195503235},{"id":"https://openalex.org/keywords/cell-migration","display_name":"cell migration","score":0.9010000228881836},{"id":"https://openalex.org/keywords/cell-adhesion","display_name":"cell adhesion","score":0.9390000104904175},{"id":"https://openalex.org/keywords/dietary-intervention","display_name":"dietary intervention","score":0.7099999785423279},{"id":"https://openalex.org/keywords/rna-sequencing","display_name":"RNA sequencing","score":0.5199999809265137}],"concepts":[{"id":"https://openalex.org/C530470458","wikidata":"https://www.wikidata.org/wiki/Q128581","display_name":"Breast cancer","level":3,"score":0.8605177998542786},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.624221920967102},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.5534112453460693},{"id":"https://openalex.org/C2775934546","wikidata":"https://www.wikidata.org/wiki/Q179991","display_name":"Biopsy","level":2,"score":0.48428457975387573},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4793608784675598},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.4791354835033417},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4516052007675171},{"id":"https://openalex.org/C535046627","wikidata":"https://www.wikidata.org/wiki/Q30612","display_name":"Clinical trial","level":2,"score":0.44066154956817627},{"id":"https://openalex.org/C2777517664","wikidata":"https://www.wikidata.org/wiki/Q4959785","display_name":"Breast biopsy","level":5,"score":0.4365561306476593},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.36901482939720154},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.3405817747116089},{"id":"https://openalex.org/C2780472235","wikidata":"https://www.wikidata.org/wiki/Q324634","display_name":"Mammography","level":4,"score":0.0694960355758667}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001707","descriptor_name":"Biopsy, Needle","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":true},{"descriptor_ui":"D001943","descriptor_name":"Breast Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009362","descriptor_name":"Neoplasm Metastasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009754","descriptor_name":"Nuts","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010865","descriptor_name":"Pilot Projects","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D012313","descriptor_name":"RNA","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D031324","descriptor_name":"Juglans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059014","descriptor_name":"High-Throughput Nucleotide Sequencing","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.nutres.2019.03.004","doi":"https://doi.org/10.1016/j.nutres.2019.03.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.nutres.2019.03.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0271531718311904/pdf","source":{"id":"https://openalex.org/S123713480","display_name":"Nutrition Research","issn_l":"0271-5317","issn":["0271-5317","1879-0739"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition Research","raw_type":"journal-article"},{"id":"pmid:30979659","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30979659","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition research (New York, N.Y.)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6853029","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6853029","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Nutr Res","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1016/j.nutres.2019.03.004","doi":"https://doi.org/10.1016/j.nutres.2019.03.004","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.nutres.2019.03.004","pdf_url":"https://www.sciencedirect.com/science/article/pii/S0271531718311904/pdf","source":{"id":"https://openalex.org/S123713480","display_name":"Nutrition Research","issn_l":"0271-5317","issn":["0271-5317","1879-0739"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-70","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Nutrition Research","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"},{"score":0.40450000762939453,"display_name":"Zero hunger","id":"https://metadata.un.org/sdg/2"}],"study_designs":[{"display_name":"Clinical Trial","id":"https://openalex.org/study-designs/clinical-trial"}],"awards":[{"id":"https://openalex.org/G2914782031","display_name":"Appalachian Center for Cellular transport in Obesity Related Disorders (ACCORD)","funder_award_id":"P20GM121299","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000856889","display_name":"West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE)","funder_award_id":"P20GM103434","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000871079","display_name":"West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health","funder_award_id":"U54GM104942","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320316600","display_name":"California Walnut Commission","ror":"https://ror.org/03bg0ms48"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2921228992.pdf","grobid_xml":"https://content.openalex.org/works/W2921228992.grobid-xml"},"referenced_works_count":59,"referenced_works":["https://openalex.org/W1575134115","https://openalex.org/W1640223309","https://openalex.org/W1743523754","https://openalex.org/W1952918887","https://openalex.org/W1975983653","https://openalex.org/W1986545748","https://openalex.org/W1987198908","https://openalex.org/W1987442108","https://openalex.org/W1992247552","https://openalex.org/W2006452399","https://openalex.org/W2008552477","https://openalex.org/W2022026491","https://openalex.org/W2029217046","https://openalex.org/W2030344361","https://openalex.org/W2035206687","https://openalex.org/W2041101454","https://openalex.org/W2048264241","https://openalex.org/W2050059294","https://openalex.org/W2061739878","https://openalex.org/W2082398379","https://openalex.org/W2083483564","https://openalex.org/W2094156327","https://openalex.org/W2096315350","https://openalex.org/W2102278945","https://openalex.org/W2108234281","https://openalex.org/W2131271579","https://openalex.org/W2131478115","https://openalex.org/W2137911744","https://openalex.org/W2141055911","https://openalex.org/W2144535642","https://openalex.org/W2145983281","https://openalex.org/W2148574282","https://openalex.org/W2150711484","https://openalex.org/W2151791302","https://openalex.org/W2151878529","https://openalex.org/W2153605106","https://openalex.org/W2155215362","https://openalex.org/W2159926956","https://openalex.org/W2162143298","https://openalex.org/W2165529124","https://openalex.org/W2170095317","https://openalex.org/W2171273651","https://openalex.org/W2179438025","https://openalex.org/W2263466750","https://openalex.org/W2273000630","https://openalex.org/W2525935580","https://openalex.org/W2530020056","https://openalex.org/W2557707278","https://openalex.org/W2607992216","https://openalex.org/W2754040259","https://openalex.org/W2757435464","https://openalex.org/W2768023942","https://openalex.org/W2770595158","https://openalex.org/W2771551779","https://openalex.org/W2777085303","https://openalex.org/W2900505218","https://openalex.org/W2945916626","https://openalex.org/W4210659358","https://openalex.org/W6637319019"],"related_works":["https://openalex.org/W2945916626","https://openalex.org/W2096315350","https://openalex.org/W2227768888","https://openalex.org/W2006452399","https://openalex.org/W2030344361","https://openalex.org/W2524799270","https://openalex.org/W2127239215","https://openalex.org/W2507352684","https://openalex.org/W4296967839","https://openalex.org/W1596400120"],"abstract_inverted_index":{"Consumption":[0],"of":[1,12,26,47,111,184,203,213,236],"walnuts":[2,112],"has":[3],"slowed":[4],"breast":[5,45,58,78,124,147,237],"cancer":[6,14,20,29,59,125],"growth":[7,30,60,233],"and/or":[8],"reduced":[9],"the":[10,103,132,146,154,192,224],"risk":[11],"mammary":[13],"in":[15,42,49,66,102,126,131,150,153,162,166,191,227],"mice.":[16,67],"The":[17,68],"benefit":[18],"against":[19],"was":[21,64,70,188],"associated":[22],"with":[23,77],"altered":[24],"expression":[25,41,152,179,183],"genes":[27,187],"for":[28,82],"and":[31,61,84,89,171,208,211,219,234],"survival.":[32],"We":[33],"hypothesized":[34],"that":[35,52,121,182,205,215],"walnut":[36,92,104,196,229],"consumption":[37,230],"would":[38,53],"alter":[39],"gene":[40,151],"pathologically":[43],"confirmed":[44,120],"cancers":[46],"women":[48,101,128],"a":[50,71],"direction":[51],"be":[54],"expected":[55],"to":[56,91,107,158,195],"decrease":[57],"survival,":[62],"as":[63],"seen":[65],"study":[69],"nonplacebo,":[72],"2-arm,":[73],"clinical":[74],"trial.":[75,133],"Women":[76],"lumps":[79,122],"large":[80],"enough":[81],"research":[83],"pathology":[85],"biopsies":[86],"were":[87,123,143,160],"recruited":[88],"randomized":[90],"consuming":[93],"or":[94],"control":[95,172],"groups.":[96,176],"Immediately":[97],"after":[98,139],"biopsy":[99],"collection,":[100],"group":[105],"began":[106],"consume":[108],"2":[109,137],"oz":[110],"per":[113],"day":[114],"until":[115],"follow-up":[116],"surgery.":[117],"Pathological":[118],"studies":[119],"all":[127],"who":[129],"remained":[130],"At":[134],"surgery,":[135],"about":[136],"weeks":[138],"biopsy,":[140],"additional":[141],"specimens":[142],"taken":[144],"from":[145],"cancers.":[148,238],"Changes":[149],"surgical":[155],"specimen":[156],"compared":[157],"baseline":[159],"determined":[161],"each":[163],"individual":[164],"woman":[165],"walnut-consuming":[167],"(n":[168,173],"=":[169,174],"5)":[170,175],"RNA":[177],"sequencing":[178],"profiling":[180],"revealed":[181],"456":[185],"identified":[186],"significantly":[189],"changed":[190],"tumor":[193],"due":[194],"consumption.":[197],"Ingenuity":[198],"Pathway":[199],"Analysis":[200],"showed":[201],"activation":[202],"pathways":[204,214],"promote":[206,216],"apoptosis":[207],"cell":[209,217],"adhesion,":[210],"inhibition":[212],"proliferation":[218],"migration.":[220],"These":[221],"results":[222],"support":[223],"hypothesis":[225],"that,":[226],"humans,":[228],"could":[231],"suppress":[232],"survival":[235]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":6},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-03-22T00:00:00"}