{"id":"https://openalex.org/W2921063703","doi":"https://doi.org/10.1042/cs072054pb","title":"Does the Addition of an Oral \u03b22 Agonist (Pirbuterol) to Long Term Oxygen Therapy Yield Further Benefit in Hypoxic Chronic Bronchitis and Emphysema?","display_name":"Does the Addition of an Oral \u03b22 Agonist (Pirbuterol) to Long Term Oxygen Therapy Yield Further Benefit in Hypoxic Chronic Bronchitis and Emphysema?","publication_year":1987,"publication_date":"1987-01-01","ids":{"openalex":"https://openalex.org/W2921063703","doi":"https://doi.org/10.1042/cs072054pb","mag":"2921063703"},"language":"en","primary_location":{"id":"doi:10.1042/cs072054pb","doi":"https://doi.org/10.1042/cs072054pb","is_oa":false,"landing_page_url":"https://doi.org/10.1042/cs072054pb","pdf_url":null,"source":{"id":"https://openalex.org/S4210209534","display_name":"Clinical Science","issn_l":"0144-9664","issn":["0144-9664"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Science","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113762640","display_name":"W Biernacki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"W Biernacki","raw_affiliation_strings":["Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112341010","display_name":"KF Whyte","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"KF Whyte","raw_affiliation_strings":["Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044711020","display_name":"Karen Prince","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"K Prince","raw_affiliation_strings":["Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050425677","display_name":"William MacNee","orcid":"https://orcid.org/0000-0002-3692-1448","observed_orcids":["https://orcid.org/0000-0002-3692-1448"]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"W MacNee","raw_affiliation_strings":["Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh","institution_ids":["https://openalex.org/I98677209"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112402921","display_name":"D. C. Flenley","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98677209","display_name":"University of Edinburgh","ror":"https://ror.org/01nrxwf90","country_code":"GB","type":"education","lineage":["https://openalex.org/I98677209"]}],"countries":["GB"],"is_corresponding":false,"raw_author_name":"DC Flenley","raw_affiliation_strings":["Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rayne Laboratory, Department of Respiratory Medicine, University of Edinburgh, City Hospital, Greenbank Drive, Edinburgh","institution_ids":["https://openalex.org/I98677209"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I98677209"],"apc_list":null,"apc_paid":null,"fwci":1.0672,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.80761416,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"72","issue":"s16","first_page":"54P","last_page":"55P"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10143","display_name":"Chronic Obstructive Pulmonary Disease (COPD) Research","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10322","display_name":"Respiratory Support and Mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pirbuterol","display_name":"pirbuterol","score":0.9959999918937683},{"id":"https://openalex.org/keywords/long-term-oxygen-therapy","display_name":"long-term oxygen therapy","score":0.9629999995231628},{"id":"https://openalex.org/keywords/emphysema","display_name":"emphysema","score":0.9570000171661377},{"id":"https://openalex.org/keywords/combination-therapy","display_name":"combination therapy","score":0.5730000138282776},{"id":"https://openalex.org/keywords/chronic-obstructive-pulmonary-disease","display_name":"chronic obstructive pulmonary disease","score":0.6420000195503235},{"id":"https://openalex.org/keywords/hypoxemia","display_name":"hypoxemia","score":0.5260000228881836},{"id":"https://openalex.org/keywords/bronchodilator-therapy","display_name":"bronchodilator therapy","score":0.6349999904632568},{"id":"https://openalex.org/keywords/exercise-capacity","display_name":"exercise capacity","score":0.4569999873638153}],"concepts":[{"id":"https://openalex.org/C2992694001","wikidata":"https://www.wikidata.org/wiki/Q173022","display_name":"Chronic bronchitis","level":2,"score":0.7220843434333801},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5905140042304993},{"id":"https://openalex.org/C2778447006","wikidata":"https://www.wikidata.org/wiki/Q1156474","display_name":"Icon","level":2,"score":0.5605601668357849},{"id":"https://openalex.org/C2779993553","wikidata":"https://www.wikidata.org/wiki/Q173022","display_name":"Bronchitis","level":2,"score":0.5071358680725098},{"id":"https://openalex.org/C2776704448","wikidata":"https://www.wikidata.org/wiki/Q754438","display_name":"Respiratory therapist","level":2,"score":0.4326328635215759},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.25118714570999146},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.22697216272354126},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.08876752853393555},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1042/cs072054pb","doi":"https://doi.org/10.1042/cs072054pb","is_oa":false,"landing_page_url":"https://doi.org/10.1042/cs072054pb","pdf_url":null,"source":{"id":"https://openalex.org/S4210209534","display_name":"Clinical Science","issn_l":"0144-9664","issn":["0144-9664"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310311608","host_organization_name":"Portland Press","host_organization_lineage":["https://openalex.org/P4310311608","https://openalex.org/P4310311715"],"host_organization_lineage_names":["Portland Press","Biochemical Society"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Clinical Science","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.9922999739646912,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2424537164","https://openalex.org/W2413146304","https://openalex.org/W2921813682","https://openalex.org/W2095588524","https://openalex.org/W2414383400","https://openalex.org/W1980772571","https://openalex.org/W2400936211","https://openalex.org/W2104875151","https://openalex.org/W3172751028","https://openalex.org/W2332228509"],"abstract_inverted_index":{"Conference":[0],"Abstract|":[1],"January":[2,255],"01":[3],"1987":[4,308],"Does":[5,228],"the":[6,229,313],"Addition":[7,230],"of":[8,35,39,66,70,97,101,128,132,159,163,231],"an":[9,232],"Oral":[10,233],"\u03b22":[11,234],"Agonist":[12,235],"(Pirbuterol)":[13,236],"to":[14,237,330],"Long":[15,238],"Term":[16,239],"Oxygen":[17,240],"Therapy":[18,241],"Yield":[19,242],"Further":[20,243],"Benefit":[21,244],"in":[22,245],"Hypoxic":[23,246],"Chronic":[24,247],"Bronchitis":[25,248],"and":[26,249,312],"Emphysema?":[27],"W":[28,30,121,123,218,224],"Biernacki;":[29],"Biernacki":[31],"1Rayne":[32,63,94,125,156],"Laboratory,":[33,64,95,126,157],"Department":[34,65,96,127,158],"Respiratory":[36,67,98,129,160],"Medicine,":[37,68,99,130,161],"University":[38,69,100,131,162],"Edinburgh,":[40,71,102,133,164],"City":[41,72,103,134,165],"Hospital,":[42,73,104,135,166],"Greenbank":[43,74,105,136,167],"Drive,":[44,75,106,137,168],"Edinburgh":[45,76,107,138,169],"Search":[46,77,108,139,170,278,285,296,298],"for":[47,78,109,140,171],"other":[48,79,110,141,172],"works":[49,80,111,142,173],"by":[50,81,112,143,174],"this":[51,82,113,144,175,331],"author":[52,83,114,145,176],"on:":[53,84,115,146,177],"This":[54,85,116,147,178,299],"Site":[55,86,117,148,179],"PubMed":[56,87,118,149,180],"Google":[57,88,119,150,181],"Scholar":[58,89,120,151,182],"KF":[59,61,220],"Whyte;":[60],"Whyte":[62],"K":[90,92,222],"Prince;":[91],"Prince":[93],"MacNee;":[122],"MacNee":[124],"DC":[152,154,226],"Flenley":[153,155],"Clin":[183,251],"Sci":[184,252],"(Lond)":[185,253],"(1987)":[186],"72":[187,257],"(s16):":[188,258],"54P\u201355P.":[189,259],"https://doi.org/10.1042/cs072054Pb":[190,261],"Views":[191,193],"Icon":[192,206,213],"Article":[194,317],"contents":[195],"Figures":[196],"&":[197],"tables":[198],"Video":[199],"Audio":[200],"Supplementary":[201],"Data":[202],"Peer":[203],"Review":[204],"Share":[205,207],"Facebook":[208],"Twitter":[209],"LinkedIn":[210],"MailTo":[211],"Cite":[212,214],"Get":[215],"Permissions":[216],"Citation":[217],"Biernacki,":[219],"Whyte,":[221],"Prince,":[223],"MacNee,":[225],"Flenley;":[227],"Emphysema?.":[250],"1":[254],"1987;":[256],"doi:":[260],"Download":[262],"citation":[263],"file:":[264],"Ris":[265],"(Zotero)":[266],"Reference":[267],"Manager":[268],"EasyBib":[269],"Bookends":[270],"Mendeley":[271],"Papers":[272],"EndNote":[273],"RefWorks":[274],"BibTex":[275],"toolbar":[276,281],"search":[277,282,283,291],"Dropdown":[279],"Menu":[280],"input":[284,286],"auto":[287],"suggest":[288],"filter":[289],"your":[290],"All":[292],"ContentAll":[293],"JournalsClinical":[294],"Science":[295],"Advanced":[297],"content":[300],"is":[301],"only":[302],"available":[303],"as":[304],"a":[305],"PDF.":[306],"\u00a9":[307],"The":[309],"Biochemical":[310],"Society":[311],"Medical":[314],"Research":[315],"Society1987":[316],"PDF":[318],"first":[319],"page":[320],"preview":[321],"Close":[322],"Modal":[323],"You":[324],"do":[325],"not":[326],"currently":[327],"have":[328],"access":[329],"content.":[332]},"counts_by_year":[],"updated_date":"2025-11-06T03:46:38.306776","created_date":"2019-03-22T00:00:00"}