{"id":"https://openalex.org/W2921054355","doi":"https://doi.org/10.1083/jcb.201807195","title":"Maturation-driven transport and AP-1\u2013dependent recycling of a secretory cargo in the Golgi","display_name":"Maturation-driven transport and AP-1\u2013dependent recycling of a secretory cargo in the Golgi","publication_year":2019,"publication_date":"2019-03-11","ids":{"openalex":"https://openalex.org/W2921054355","doi":"https://doi.org/10.1083/jcb.201807195","mag":"2921054355","pmid":"https://pubmed.ncbi.nlm.nih.gov/30858194","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6504904"},"language":"en","primary_location":{"id":"doi:10.1083/jcb.201807195","doi":"https://doi.org/10.1083/jcb.201807195","is_oa":true,"landing_page_url":"https://doi.org/10.1083/jcb.201807195","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cell Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1083/jcb.201807195","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5004589042","display_name":"Jason C. Casler","orcid":"https://orcid.org/0000-0001-9742-9978","observed_orcids":["https://orcid.org/0000-0001-9742-9978"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jason C. Casler","raw_affiliation_strings":["Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL"],"raw_orcid":"https://orcid.org/0000-0001-9742-9978","affiliations":[{"raw_affiliation_string":"Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037330571","display_name":"Effrosyni Papanikou","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Effrosyni Papanikou","raw_affiliation_strings":["Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034754389","display_name":"Juan J. Barrero","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Juan J. Barrero","raw_affiliation_strings":["Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL","institution_ids":["https://openalex.org/I40347166"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006514294","display_name":"Benjamin S. Glick","orcid":"https://orcid.org/0000-0002-7921-1374","observed_orcids":["https://orcid.org/0000-0002-7921-1374"]},"institutions":[{"id":"https://openalex.org/I40347166","display_name":"University of Chicago","ror":"https://ror.org/024mw5h28","country_code":"US","type":"education","lineage":["https://openalex.org/I40347166"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Benjamin S. Glick","raw_affiliation_strings":["Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL"],"raw_orcid":"https://orcid.org/0000-0002-7921-1374","affiliations":[{"raw_affiliation_string":"Department of Molecular Genetics and Cell Biology, University of Chicago, Chicago, IL","institution_ids":["https://openalex.org/I40347166"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5006514294"],"corresponding_institution_ids":["https://openalex.org/I40347166"],"apc_list":null,"apc_paid":null,"fwci":5.6905,"has_fulltext":false,"cited_by_count":80,"citation_normalized_percentile":{"value":0.9729541,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"218","issue":"5","first_page":"1582","last_page":"1601"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10587","display_name":"Autophagy in Disease and Therapy","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10497","display_name":"Fungal and yeast genetics research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/golgi-maturation","display_name":"Golgi maturation","score":0.8669999837875366},{"id":"https://openalex.org/keywords/golgi-cisternae","display_name":"Golgi cisternae","score":0.9340000152587891},{"id":"https://openalex.org/keywords/er-exit","display_name":"ER exit","score":0.367000013589859}],"concepts":[{"id":"https://openalex.org/C119062480","wikidata":"https://www.wikidata.org/wiki/Q83181","display_name":"Golgi apparatus","level":3,"score":0.9257231950759888},{"id":"https://openalex.org/C6492254","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretory pathway","level":4,"score":0.7936515212059021},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.7189862728118896},{"id":"https://openalex.org/C156399914","wikidata":"https://www.wikidata.org/wiki/Q7444454","display_name":"Secretory protein","level":3,"score":0.6525701284408569},{"id":"https://openalex.org/C49039625","wikidata":"https://www.wikidata.org/wiki/Q84230","display_name":"Secretion","level":2,"score":0.6241883635520935},{"id":"https://openalex.org/C57581600","wikidata":"https://www.wikidata.org/wiki/Q2449730","display_name":"Transport protein","level":2,"score":0.4787108898162842},{"id":"https://openalex.org/C206912223","wikidata":"https://www.wikidata.org/wiki/Q21111963","display_name":"COPI","level":5,"score":0.47247573733329773},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.4683992564678192},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.3526386022567749},{"id":"https://openalex.org/C158617107","wikidata":"https://www.wikidata.org/wiki/Q79927","display_name":"Endoplasmic reticulum","level":2,"score":0.22488602995872498},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.1883346438407898}],"mesh":[{"descriptor_ui":"D001692","descriptor_name":"Biological Transport","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004721","descriptor_name":"Endoplasmic Reticulum","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D006056","descriptor_name":"Golgi Apparatus","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D007425","descriptor_name":"Intracellular Membranes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D008856","descriptor_name":"Microscopy, Fluorescence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D018808","descriptor_name":"Transcription Factor AP-1","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D029701","descriptor_name":"Saccharomyces cerevisiae Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1083/jcb.201807195","doi":"https://doi.org/10.1083/jcb.201807195","is_oa":true,"landing_page_url":"https://doi.org/10.1083/jcb.201807195","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cell Biology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5797182","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6504904","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6504904","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6504904","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Cell Biol","raw_type":"Text"},{"id":"pmid:30858194","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30858194","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of cell biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1083/jcb.201807195","doi":"https://doi.org/10.1083/jcb.201807195","is_oa":true,"landing_page_url":"https://doi.org/10.1083/jcb.201807195","pdf_url":null,"source":{"id":"https://openalex.org/S96410829","display_name":"The Journal of Cell Biology","issn_l":"0021-9525","issn":["0021-9525","1540-8140"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1"],"host_organization":"https://openalex.org/P4310315676","host_organization_name":"Rockefeller University Press","host_organization_lineage":["https://openalex.org/P4310315676"],"host_organization_lineage_names":["Rockefeller University Press"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Cell Biology","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1656657801","display_name":"Dissecting the functions of yeast COPI","funder_award_id":"R01GM104010","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G2837947413","display_name":"Molecular and Cellular Biology Training","funder_award_id":"T32GM007183","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000865577","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA014599","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":106,"referenced_works":["https://openalex.org/W180268708","https://openalex.org/W1499112972","https://openalex.org/W1504929892","https://openalex.org/W1515472397","https://openalex.org/W1895666910","https://openalex.org/W1967131697","https://openalex.org/W1968242602","https://openalex.org/W1972984650","https://openalex.org/W1979348380","https://openalex.org/W1983087192","https://openalex.org/W1984311414","https://openalex.org/W1988980633","https://openalex.org/W1994528127","https://openalex.org/W1994624166","https://openalex.org/W1996227803","https://openalex.org/W1997859335","https://openalex.org/W2003519864","https://openalex.org/W2005733184","https://openalex.org/W2009288698","https://openalex.org/W2010378383","https://openalex.org/W2013314128","https://openalex.org/W2015438927","https://openalex.org/W2017735078","https://openalex.org/W2024431372","https://openalex.org/W2024747540","https://openalex.org/W2025960504","https://openalex.org/W2028004137","https://openalex.org/W2030668068","https://openalex.org/W2034145518","https://openalex.org/W2036527573","https://openalex.org/W2037185463","https://openalex.org/W2038107094","https://openalex.org/W2038596110","https://openalex.org/W2046332353","https://openalex.org/W2046640957","https://openalex.org/W2053890782","https://openalex.org/W2055659813","https://openalex.org/W2074698758","https://openalex.org/W2080419619","https://openalex.org/W2081871112","https://openalex.org/W2082427481","https://openalex.org/W2086983969","https://openalex.org/W2087112393","https://openalex.org/W2092161435","https://openalex.org/W2093978361","https://openalex.org/W2094181260","https://openalex.org/W2094706331","https://openalex.org/W2099413525","https://openalex.org/W2100057937","https://openalex.org/W2102600657","https://openalex.org/W2104152066","https://openalex.org/W2105376178","https://openalex.org/W2106723429","https://openalex.org/W2110221241","https://openalex.org/W2111591755","https://openalex.org/W2113267766","https://openalex.org/W2114827973","https://openalex.org/W2115853386","https://openalex.org/W2120620631","https://openalex.org/W2120996859","https://openalex.org/W2129788878","https://openalex.org/W2133112673","https://openalex.org/W2133211760","https://openalex.org/W2133871547","https://openalex.org/W2136133782","https://openalex.org/W2136176984","https://openalex.org/W2137791756","https://openalex.org/W2141928263","https://openalex.org/W2143106919","https://openalex.org/W2146568672","https://openalex.org/W2147099977","https://openalex.org/W2147718557","https://openalex.org/W2148114086","https://openalex.org/W2148417653","https://openalex.org/W2152708819","https://openalex.org/W2152726884","https://openalex.org/W2154083208","https://openalex.org/W2158535876","https://openalex.org/W2165310868","https://openalex.org/W2167650443","https://openalex.org/W2169375617","https://openalex.org/W2169562535","https://openalex.org/W2169597956","https://openalex.org/W2170171321","https://openalex.org/W2256936125","https://openalex.org/W2265713480","https://openalex.org/W2273743338","https://openalex.org/W2274582346","https://openalex.org/W2287403443","https://openalex.org/W2323529956","https://openalex.org/W2463083241","https://openalex.org/W2503380171","https://openalex.org/W2507571573","https://openalex.org/W2511783360","https://openalex.org/W2512982808","https://openalex.org/W2751459069","https://openalex.org/W2760834034","https://openalex.org/W2782601702","https://openalex.org/W2797682301","https://openalex.org/W2886128958","https://openalex.org/W2895816064","https://openalex.org/W2899595813","https://openalex.org/W2922438548","https://openalex.org/W4210968093","https://openalex.org/W4238009417","https://openalex.org/W4241358477"],"related_works":["https://openalex.org/W2922438548","https://openalex.org/W3154516936","https://openalex.org/W2158535876","https://openalex.org/W3208194432","https://openalex.org/W2029167074","https://openalex.org/W1991257080","https://openalex.org/W1599896138","https://openalex.org/W4414453728","https://openalex.org/W7132589604","https://openalex.org/W4416644655"],"abstract_inverted_index":{",":[0],"but":[1],"those":[2],"experiments":[3],"did":[4],"not":[5],"track":[6],"passage":[7],"of":[8,53,107],"a":[9,16,38,54,105],"secretory":[10,17,41,87,94,112,133],"cargo.":[11,88],"The":[12,56],"expectation":[13],"is":[14,103],"that":[15,43,104,129],"cargo":[18,42,95,113,134],"will":[19],"be":[20],"continuously":[21],"present":[22],"within":[23],"maturing":[24],"cisternae":[25,77,91,116],"as":[26,136,138],"resident":[27,139],"Golgi":[28,70,76,120,140],"proteins":[29,135],"arrive":[30],"and":[31,63,68,82],"depart.":[32],"We":[33],"tested":[34],"this":[35],"idea":[36],"using":[37],"regulatable":[39],"fluorescent":[40],"forms":[44],"ER-localized":[45],"aggregates,":[46],"which":[47],"dissociate":[48],"into":[49],"tetramers":[50,58],"upon":[51],"addition":[52],"ligand.":[55],"solubilized":[57],"rapidly":[59],"exit":[60],"the":[61,80,86,93,97,118,125],"ER":[62,81],"then":[64],"transit":[65],"through":[66],"early":[67],"late":[69],"compartments":[71],"before":[72],"being":[73],"secreted.":[74],"Early":[75],"form":[78],"near":[79],"become":[83],"loaded":[84],"with":[85],"As":[89],"predicted,":[90],"contain":[92],"throughout":[96],"maturation":[98],"process.":[99],"An":[100],"unexpected":[101],"finding":[102],"burst":[106],"intra-Golgi":[108],"recycling":[109,123],"delivers":[110],"additional":[111],"molecules":[114],"to":[115],"during":[117],"early-to-late":[119],"transition.":[121],"This":[122],"requires":[124],"AP-1":[126,130],"adaptor,":[127],"suggesting":[128],"can":[131],"recycle":[132],"well":[137],"proteins.":[141]},"counts_by_year":[{"year":2026,"cited_by_count":12},{"year":2025,"cited_by_count":7},{"year":2024,"cited_by_count":11},{"year":2023,"cited_by_count":7},{"year":2022,"cited_by_count":13},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":13},{"year":2019,"cited_by_count":11}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-03-22T00:00:00"}