{"id":"https://openalex.org/W2920945271","doi":"https://doi.org/10.1016/j.ajg.2019.01.011","title":"Circulating microRNA-155 is associated with insulin resistance in chronic hepatitis C patients","display_name":"Circulating microRNA-155 is associated with insulin resistance in chronic hepatitis C patients","publication_year":2019,"publication_date":"2019-03-01","ids":{"openalex":"https://openalex.org/W2920945271","doi":"https://doi.org/10.1016/j.ajg.2019.01.011","mag":"2920945271","pmid":"https://pubmed.ncbi.nlm.nih.gov/30852102"},"language":"en","primary_location":{"id":"doi:10.1016/j.ajg.2019.01.011","doi":"https://doi.org/10.1016/j.ajg.2019.01.011","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ajg.2019.01.011","pdf_url":null,"source":{"id":"https://openalex.org/S106979931","display_name":"Arab Journal of Gastroenterology","issn_l":"1687-1979","issn":["1687-1979","2090-2387"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arab Journal of Gastroenterology","raw_type":"journal-article"},"parent_works":[],"lineage":["https://openalex.org/W2920945271"],"child_works_count":0,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5071538191","display_name":"Nourhan M. El Samaloty","orcid":"https://orcid.org/0009-0005-2180-6788","observed_orcids":["https://orcid.org/0009-0005-2180-6788"]},"institutions":[{"id":"https://openalex.org/I186217134","display_name":"Future University in Egypt","ror":"https://ror.org/03s8c2x09","country_code":"EG","type":"education","lineage":["https://openalex.org/I186217134"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Nourhan M. El Samaloty","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Future University, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Future University, Egypt","institution_ids":["https://openalex.org/I186217134"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5104006408","display_name":"Zeinab A. Hassan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I84058292","display_name":"Helwan University","ror":"https://ror.org/00h55v928","country_code":"EG","type":"education","lineage":["https://openalex.org/I84058292"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Zeinab A. Hassan","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Egypt","institution_ids":["https://openalex.org/I84058292"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5019179377","display_name":"Zeinab M. Hefny","orcid":"https://orcid.org/0000-0003-3146-9402","observed_orcids":["https://orcid.org/0000-0003-3146-9402"]},"institutions":[{"id":"https://openalex.org/I107720978","display_name":"Ain Shams University","ror":"https://ror.org/00cb9w016","country_code":"EG","type":"education","lineage":["https://openalex.org/I107720978"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Zeinab M. Hefny","raw_affiliation_strings":["Department of Tropical Medicine, Faculty of Medicine Ain Shams University, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Tropical Medicine, Faculty of Medicine Ain Shams University, Egypt","institution_ids":["https://openalex.org/I107720978"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5083108996","display_name":"Dalia H. Abdelaziz","orcid":"https://orcid.org/0000-0001-6388-3021","observed_orcids":["https://orcid.org/0000-0001-6388-3021"]},"institutions":[{"id":"https://openalex.org/I84058292","display_name":"Helwan University","ror":"https://ror.org/00h55v928","country_code":"EG","type":"education","lineage":["https://openalex.org/I84058292"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Dalia H.A. Abdelaziz","raw_affiliation_strings":["Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Egypt. Electronic address: dalia_abdelaziz@pharm.helwan.edu.eg","Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Egypt. Electronic address: dalia_abdelaziz@pharm.helwan.edu.eg","institution_ids":["https://openalex.org/I84058292"]},{"raw_affiliation_string":"Department of Biochemistry and Molecular Biology, Faculty of Pharmacy, Helwan University, Egypt","institution_ids":["https://openalex.org/I84058292"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5083108996"],"corresponding_institution_ids":["https://openalex.org/I84058292"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.5269,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.53087158,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"20","issue":"1","first_page":"1","last_page":"7"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9208999872207642,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","score":0.9208999872207642,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10151","display_name":"Hepatitis C virus research","score":0.05979999899864197,"subfield":{"id":"https://openalex.org/subfields/2721","display_name":"Hepatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10528","display_name":"Adipokines, Inflammation, and Metabolic Diseases","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/mir-155","display_name":"miR-155","score":0.8799999952316284},{"id":"https://openalex.org/keywords/mir-34a","display_name":"miR-34a","score":0.9739999771118164},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.8059999942779541},{"id":"https://openalex.org/keywords/chronic-hepatitis-c","display_name":"chronic hepatitis C","score":0.847000002861023},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9779999852180481},{"id":"https://openalex.org/keywords/circulating-micrornas","display_name":"circulating microRNAs","score":0.8429999947547913},{"id":"https://openalex.org/keywords/homa-ir","display_name":"HOMA-IR","score":0.9729999899864197},{"id":"https://openalex.org/keywords/fasting-blood-glucose","display_name":"fasting blood glucose","score":0.8230000138282776},{"id":"https://openalex.org/keywords/hba1c","display_name":"HbA1c","score":0.9359999895095825}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9031915664672852},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.8314067125320435},{"id":"https://openalex.org/C2776408679","wikidata":"https://www.wikidata.org/wiki/Q708693","display_name":"Hepatitis C virus","level":3,"score":0.6619958877563477},{"id":"https://openalex.org/C2780942790","wikidata":"https://www.wikidata.org/wiki/Q372016","display_name":"Pathogenesis","level":2,"score":0.6455226540565491},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6440991759300232},{"id":"https://openalex.org/C145059251","wikidata":"https://www.wikidata.org/wiki/Q310899","display_name":"microRNA","level":3,"score":0.6042447686195374},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.5414784550666809},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5329440832138062},{"id":"https://openalex.org/C2778455985","wikidata":"https://www.wikidata.org/wiki/Q17553105","display_name":"miR-155","level":4,"score":0.50551438331604},{"id":"https://openalex.org/C2776455275","wikidata":"https://www.wikidata.org/wiki/Q154869","display_name":"Hepatitis C","level":2,"score":0.44485044479370117},{"id":"https://openalex.org/C3020491458","wikidata":"https://www.wikidata.org/wiki/Q131742","display_name":"Chronic hepatitis","level":3,"score":0.4248647093772888},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.41894134879112244},{"id":"https://openalex.org/C2779306644","wikidata":"https://www.wikidata.org/wiki/Q2002370","display_name":"Insulin","level":2,"score":0.4147634208202362},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.3864348530769348},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.3175703287124634},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.203520268201828},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.05560329556465149},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001786","descriptor_name":"Blood Glucose","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D005215","descriptor_name":"Fasting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006442","descriptor_name":"Glycated Hemoglobin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D006706","descriptor_name":"Homeostasis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007333","descriptor_name":"Insulin Resistance","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012372","descriptor_name":"ROC Curve","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D019698","descriptor_name":"Hepatitis C, Chronic","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D035683","descriptor_name":"MicroRNAs","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/j.ajg.2019.01.011","doi":"https://doi.org/10.1016/j.ajg.2019.01.011","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.ajg.2019.01.011","pdf_url":null,"source":{"id":"https://openalex.org/S106979931","display_name":"Arab Journal of Gastroenterology","issn_l":"1687-1979","issn":["1687-1979","2090-2387"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","doyens","jufo-1","medline","norway-1","poland-40","russia-white-list-3"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arab Journal of Gastroenterology","raw_type":"journal-article"},{"id":"pmid:30852102","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30852102","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Arab journal of gastroenterology : the official publication of the Pan-Arab Association of Gastroenterology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W197220479","https://openalex.org/W999297528","https://openalex.org/W1846153459","https://openalex.org/W1928264125","https://openalex.org/W1981533568","https://openalex.org/W1983330294","https://openalex.org/W1986611197","https://openalex.org/W1989277040","https://openalex.org/W1998404710","https://openalex.org/W2001927173","https://openalex.org/W2006426795","https://openalex.org/W2017857120","https://openalex.org/W2019900254","https://openalex.org/W2026051181","https://openalex.org/W2027744584","https://openalex.org/W2045104691","https://openalex.org/W2079179255","https://openalex.org/W2082842671","https://openalex.org/W2092896071","https://openalex.org/W2113546559","https://openalex.org/W2114593036","https://openalex.org/W2122340765","https://openalex.org/W2126327417","https://openalex.org/W2127669794","https://openalex.org/W2135020806","https://openalex.org/W2135613885","https://openalex.org/W2153863419","https://openalex.org/W2160007613","https://openalex.org/W2160234571","https://openalex.org/W2171139781","https://openalex.org/W2335465643","https://openalex.org/W2520432709","https://openalex.org/W2624987749","https://openalex.org/W2757901891","https://openalex.org/W4241151929","https://openalex.org/W6626107799","https://openalex.org/W6645946006"],"related_works":["https://openalex.org/W2792817654","https://openalex.org/W1917610271","https://openalex.org/W3012326976","https://openalex.org/W2189559993","https://openalex.org/W2018889072","https://openalex.org/W2598355860","https://openalex.org/W2567006135","https://openalex.org/W1976697043","https://openalex.org/W2408324842","https://openalex.org/W1539508805"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-12T12:28:57.059296","created_date":"2019-03-22T00:00:00"}