{"id":"https://openalex.org/W2915061501","doi":"https://doi.org/10.3389/fendo.2019.00008","title":"A Perception on Genome-Wide Genetic Analysis of Metabolic Traits in Arab Populations","display_name":"A Perception on Genome-Wide Genetic Analysis of Metabolic Traits in Arab Populations","publication_year":2019,"publication_date":"2019-01-28","ids":{"openalex":"https://openalex.org/W2915061501","doi":"https://doi.org/10.3389/fendo.2019.00008","mag":"2915061501","pmid":"https://pubmed.ncbi.nlm.nih.gov/30761081","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6362414"},"language":"en","primary_location":{"id":"doi:10.3389/fendo.2019.00008","doi":"https://doi.org/10.3389/fendo.2019.00008","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2019.00008","pdf_url":"https://www.frontiersin.org/articles/10.3389/fendo.2019.00008/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fendo.2019.00008/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5040018838","display_name":"Prashantha Hebbar","orcid":"https://orcid.org/0000-0001-6560-7063","observed_orcids":["https://orcid.org/0000-0001-6560-7063"]},"institutions":[{"id":"https://openalex.org/I133731052","display_name":"University of Helsinki","ror":"https://ror.org/040af2s02","country_code":"FI","type":"education","lineage":["https://openalex.org/I133731052"]},{"id":"https://openalex.org/I4210165735","display_name":"Dasman Diabetes Institute","ror":"https://ror.org/05tppc012","country_code":"KW","type":"education","lineage":["https://openalex.org/I4210165735"]}],"countries":["FI","KW"],"is_corresponding":false,"raw_author_name":"Prashantha Hebbar","raw_affiliation_strings":["Doctoral Program in Population Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland","Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Doctoral Program in Population Health, Faculty of Medicine, University of Helsinki, Helsinki, Finland","institution_ids":["https://openalex.org/I133731052"]},{"raw_affiliation_string":"Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait","institution_ids":["https://openalex.org/I4210165735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036936439","display_name":"Jehad Ahmed Abubaker","orcid":"https://orcid.org/0000-0003-0681-7305","observed_orcids":["https://orcid.org/0000-0003-0681-7305"]},"institutions":[{"id":"https://openalex.org/I4210165735","display_name":"Dasman Diabetes Institute","ror":"https://ror.org/05tppc012","country_code":"KW","type":"education","lineage":["https://openalex.org/I4210165735"]}],"countries":["KW"],"is_corresponding":false,"raw_author_name":"Jehad Ahmed Abubaker","raw_affiliation_strings":["Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait","institution_ids":["https://openalex.org/I4210165735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5076487680","display_name":"Mohamed Abu\u2010Farha","orcid":"https://orcid.org/0000-0001-8357-1252","observed_orcids":["https://orcid.org/0000-0001-8357-1252"]},"institutions":[{"id":"https://openalex.org/I4210165735","display_name":"Dasman Diabetes Institute","ror":"https://ror.org/05tppc012","country_code":"KW","type":"education","lineage":["https://openalex.org/I4210165735"]}],"countries":["KW"],"is_corresponding":false,"raw_author_name":"Mohamed Abu-Farha","raw_affiliation_strings":["Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait","institution_ids":["https://openalex.org/I4210165735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101494462","display_name":"Jaakko Tuomilehto","orcid":"https://orcid.org/0000-0002-8306-6202","observed_orcids":["https://orcid.org/0000-0002-8306-6202","https://orcid.org/0000-0002-5017-7344","https://orcid.org/0000-0002-3424-0745","https://orcid.org/0000-0003-1909-7407","https://orcid.org/0009-0005-2384-549X"]},"institutions":[{"id":"https://openalex.org/I4210165735","display_name":"Dasman Diabetes Institute","ror":"https://ror.org/05tppc012","country_code":"KW","type":"education","lineage":["https://openalex.org/I4210165735"]}],"countries":["KW"],"is_corresponding":false,"raw_author_name":"Jaakko Tuomilehto","raw_affiliation_strings":["Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait","institution_ids":["https://openalex.org/I4210165735"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045720408","display_name":"Fahd Al\u2010Mulla","orcid":"https://orcid.org/0000-0001-5409-3829","observed_orcids":["https://orcid.org/0000-0001-5409-3829"]},"institutions":[{"id":"https://openalex.org/I4210165735","display_name":"Dasman Diabetes Institute","ror":"https://ror.org/05tppc012","country_code":"KW","type":"education","lineage":["https://openalex.org/I4210165735"]}],"countries":["KW"],"is_corresponding":true,"raw_author_name":"Fahd Al-Mulla","raw_affiliation_strings":["Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait","institution_ids":["https://openalex.org/I4210165735"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043950009","display_name":"Thangavel Alphonse Thanaraj","orcid":"https://orcid.org/0000-0002-4574-5343","observed_orcids":["https://orcid.org/0000-0002-4574-5343"]},"institutions":[{"id":"https://openalex.org/I4210165735","display_name":"Dasman Diabetes Institute","ror":"https://ror.org/05tppc012","country_code":"KW","type":"education","lineage":["https://openalex.org/I4210165735"]}],"countries":["KW"],"is_corresponding":true,"raw_author_name":"Thangavel Alphonse Thanaraj","raw_affiliation_strings":["Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Genetics and Bioinformatics Unit, Dasman Diabetes Institute, Kuwait City, Kuwait","institution_ids":["https://openalex.org/I4210165735"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5043950009","https://openalex.org/A5045720408"],"corresponding_institution_ids":["https://openalex.org/I4210165735"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":2.059,"has_fulltext":true,"cited_by_count":20,"citation_normalized_percentile":{"value":0.86365825,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":null,"first_page":"8","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9848999977111816,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.004900000058114529,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13984","display_name":"Nutrition, Genetics, and Disease","score":0.0032999999821186066,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/arabs","display_name":"Arabs","score":0.7200000286102295},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.734000027179718},{"id":"https://openalex.org/keywords/susceptibility-loci","display_name":"genetic susceptibility loci","score":0.9240000247955322},{"id":"https://openalex.org/keywords/genome-wide-association-study","display_name":"genome-wide association study","score":0.7889999747276306},{"id":"https://openalex.org/keywords/metabolic-disorders","display_name":"metabolic disorders","score":0.5989999771118164},{"id":"https://openalex.org/keywords/consanguinity","display_name":"consanguinity","score":0.8769999742507935},{"id":"https://openalex.org/keywords/inbreeding","display_name":"inbreeding","score":0.921999990940094},{"id":"https://openalex.org/keywords/recessive-mutations","display_name":"recessive mutations","score":0.8500000238418579},{"id":"https://openalex.org/keywords/lipid-profile","display_name":"lipid profile","score":0.6650000214576721},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.9200000166893005},{"id":"https://openalex.org/keywords/blood-pressure","display_name":"blood pressure","score":0.925000011920929},{"id":"https://openalex.org/keywords/anthropometry","display_name":"anthropometry","score":0.9729999899864197},{"id":"https://openalex.org/keywords/genetic-architecture","display_name":"genetic architecture","score":0.6100000143051147},{"id":"https://openalex.org/keywords/pleiotropy","display_name":"pleiotropy","score":0.6990000009536743},{"id":"https://openalex.org/keywords/kuwait","display_name":"Kuwait","score":0.5}],"concepts":[{"id":"https://openalex.org/C9287583","wikidata":"https://www.wikidata.org/wiki/Q5532883","display_name":"Genetic architecture","level":4,"score":0.6980205774307251},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.6157563924789429},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.605546236038208},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6050312519073486},{"id":"https://openalex.org/C106208931","wikidata":"https://www.wikidata.org/wiki/Q1098876","display_name":"Genome-wide association study","level":5,"score":0.5922815799713135},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.47490087151527405},{"id":"https://openalex.org/C2776116246","wikidata":"https://www.wikidata.org/wiki/Q21067469","display_name":"Runs of Homozygosity","level":5,"score":0.47067007422447205},{"id":"https://openalex.org/C81941488","wikidata":"https://www.wikidata.org/wiki/Q853421","display_name":"Quantitative trait locus","level":3,"score":0.47040778398513794},{"id":"https://openalex.org/C161600633","wikidata":"https://www.wikidata.org/wiki/Q18031867","display_name":"HNF1A","level":3,"score":0.46669867634773254},{"id":"https://openalex.org/C2779923321","wikidata":"https://www.wikidata.org/wiki/Q774347","display_name":"Consanguinity","level":2,"score":0.4630119800567627},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.23345351219177246},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.1905164122581482},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.16451817750930786},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.13826745748519897},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.12348726391792297}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3389/fendo.2019.00008","doi":"https://doi.org/10.3389/fendo.2019.00008","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2019.00008","pdf_url":"https://www.frontiersin.org/articles/10.3389/fendo.2019.00008/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5360057","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6362414","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:30761081","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30761081","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in endocrinology","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6362414","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6362414/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Endocrinol (Lausanne)","raw_type":"Text"},{"id":"pmh:oai:helda.helsinki.fi:10138/298920","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10138/298920","pdf_url":"http://hdl.handle.net/10138/298920","source":{"id":"https://openalex.org/S4210213322","display_name":"Ty\u00f6v\u00e4entutkimus Vuosikirja","issn_l":"0784-1272","issn":["0784-1272","1459-7780"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":["ddh","jufo-1"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"},{"id":"pmh:oai:doaj.org/article:cdcd0a089b884435a4c7f641e9af3448","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/cdcd0a089b884435a4c7f641e9af3448","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Endocrinology, Vol 10 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fendo.2019.00008","doi":"https://doi.org/10.3389/fendo.2019.00008","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fendo.2019.00008","pdf_url":"https://www.frontiersin.org/articles/10.3389/fendo.2019.00008/pdf","source":{"id":"https://openalex.org/S2597401208","display_name":"Frontiers in Endocrinology","issn_l":"1664-2392","issn":["1664-2392"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Endocrinology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5681110726","display_name":null,"funder_award_id":"RA 2016-026","funder_id":"https://openalex.org/F4320323287","funder_display_name":"Dasman Diabetes Institute"}],"funders":[{"id":"https://openalex.org/F4320323287","display_name":"Dasman Diabetes Institute","ror":"https://ror.org/05tppc012"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2915061501.pdf","grobid_xml":"https://content.openalex.org/works/W2915061501.grobid-xml"},"referenced_works_count":125,"referenced_works":["https://openalex.org/W266695522","https://openalex.org/W1203882361","https://openalex.org/W1528907477","https://openalex.org/W1532333574","https://openalex.org/W1771830197","https://openalex.org/W1808248494","https://openalex.org/W1925664165","https://openalex.org/W1964897601","https://openalex.org/W1966775465","https://openalex.org/W1969083035","https://openalex.org/W1970229717","https://openalex.org/W1975341011","https://openalex.org/W1977390594","https://openalex.org/W1977835139","https://openalex.org/W1978150238","https://openalex.org/W1980991473","https://openalex.org/W1985052795","https://openalex.org/W1985547787","https://openalex.org/W1988185165","https://openalex.org/W1988291375","https://openalex.org/W1989627165","https://openalex.org/W1993564909","https://openalex.org/W1996094501","https://openalex.org/W1996294093","https://openalex.org/W1999286267","https://openalex.org/W1999361718","https://openalex.org/W1999398931","https://openalex.org/W2003132592","https://openalex.org/W2007255157","https://openalex.org/W2009715702","https://openalex.org/W2012651041","https://openalex.org/W2012798356","https://openalex.org/W2013056329","https://openalex.org/W2017395110","https://openalex.org/W2018782102","https://openalex.org/W2019983262","https://openalex.org/W2025539853","https://openalex.org/W2025745055","https://openalex.org/W2025891649","https://openalex.org/W2025989795","https://openalex.org/W2026333937","https://openalex.org/W2026416497","https://openalex.org/W2029872840","https://openalex.org/W2037336230","https://openalex.org/W2045153152","https://openalex.org/W2045773349","https://openalex.org/W2048458004","https://openalex.org/W2055262785","https://openalex.org/W2057269950","https://openalex.org/W2059417788","https://openalex.org/W2065221099","https://openalex.org/W2069717999","https://openalex.org/W2069895399","https://openalex.org/W2079927753","https://openalex.org/W2088486634","https://openalex.org/W2091837348","https://openalex.org/W2093486575","https://openalex.org/W2093900806","https://openalex.org/W2097148973","https://openalex.org/W2099562966","https://openalex.org/W2102891551","https://openalex.org/W2103714979","https://openalex.org/W2104953797","https://openalex.org/W2108065192","https://openalex.org/W2110808585","https://openalex.org/W2112547080","https://openalex.org/W2116790770","https://openalex.org/W2119444539","https://openalex.org/W2120827716","https://openalex.org/W2123782003","https://openalex.org/W2123907851","https://openalex.org/W2124458216","https://openalex.org/W2125277331","https://openalex.org/W2126718294","https://openalex.org/W2127450586","https://openalex.org/W2129053536","https://openalex.org/W2132464305","https://openalex.org/W2134785557","https://openalex.org/W2138274838","https://openalex.org/W2138842039","https://openalex.org/W2140126911","https://openalex.org/W2140715205","https://openalex.org/W2142769596","https://openalex.org/W2148951021","https://openalex.org/W2152434143","https://openalex.org/W2153118028","https://openalex.org/W2153554912","https://openalex.org/W2156443053","https://openalex.org/W2157752701","https://openalex.org/W2157784421","https://openalex.org/W2159422401","https://openalex.org/W2163142374","https://openalex.org/W2163710303","https://openalex.org/W2166711199","https://openalex.org/W2166941513","https://openalex.org/W2167638767","https://openalex.org/W2171637863","https://openalex.org/W2178863062","https://openalex.org/W2267023751","https://openalex.org/W2279723444","https://openalex.org/W2289554893","https://openalex.org/W2292216198","https://openalex.org/W2339719708","https://openalex.org/W2410278634","https://openalex.org/W2462886043","https://openalex.org/W2489911374","https://openalex.org/W2561301122","https://openalex.org/W2565540700","https://openalex.org/W2577221503","https://openalex.org/W2581817027","https://openalex.org/W2593219710","https://openalex.org/W2606375264","https://openalex.org/W2725988230","https://openalex.org/W2728648841","https://openalex.org/W2769291786","https://openalex.org/W2775357565","https://openalex.org/W2785909275","https://openalex.org/W2791663818","https://openalex.org/W2791896879","https://openalex.org/W2886761993","https://openalex.org/W2894662039","https://openalex.org/W2894877329","https://openalex.org/W2899168038","https://openalex.org/W2914578412","https://openalex.org/W6759391920"],"related_works":["https://openalex.org/W3086433706","https://openalex.org/W2577221503","https://openalex.org/W7009162081","https://openalex.org/W3206846422","https://openalex.org/W3214223573","https://openalex.org/W2922426123","https://openalex.org/W4401213117","https://openalex.org/W3202819736","https://openalex.org/W3003673597","https://openalex.org/W2410278634"],"abstract_inverted_index":{"Despite":[0],"dedicated":[1],"nation-wide":[2],"efforts":[3],"to":[4,21,52,144,167,176,211],"raise":[5],"awareness":[6],"against":[7],"the":[8,17,31,34,46,146,168,178,186,190,192,203,212,217],"harmful":[9],"effects":[10,219],"of":[11,48,170,189,194,201,205,208,214,220],"fast-food":[12],"consumption":[13],"and":[14,45,111,159,216,232,243],"sedentary":[15],"lifestyle,":[16],"Arab":[18,35,117,140,247],"population":[19,36,54],"continues":[20],"struggle":[22],"with":[23,153,241],"an":[24],"increased":[25],"risk":[26,40,50,69,85,238],"for":[27,42,76,149,235],"metabolic":[28,43,225],"disorders.":[29,226],"Unlike":[30],"European":[32],"population,":[33,191],"lacks":[37],"well-established":[38],"genetic":[39,68,147,187,195,206,237],"determinants":[41,148],"disorders,":[44],"transferability":[47],"established":[49,179],"loci":[51,70,86],"this":[53,131],"has":[55],"not":[56],"been":[57,114],"satisfactorily":[58],"demonstrated.":[59],"The":[60],"most":[61],"recent":[62],"findings":[63],"have":[64,113],"identified":[65],"over":[66],"240":[67],"(with":[71],"~400":[72],"independent":[73],"association":[74,126,137],"signals)":[75],"type":[77],"2":[78],"diabetes,":[79],"but":[80],"thus":[81],"far":[82],"only":[83],"25":[84],"(ADAMTS9,":[87],"ALX4,":[88],"BCL11A,":[89],"CDKAL1,":[90],"CDKN2A/B,":[91],"COL8A1,":[92],"DUSP9,":[93],"FTO,":[94],"GCK,":[95],"GNPDA2,":[96],"HMG20A,":[97],"HNF1A,":[98],"HNF1B,":[99],"HNF4A,":[100],"IGF2BP2,":[101],"JAZF1,":[102],"KCNJ11,":[103],"KCNQ1,":[104],"MC4R,":[105],"PPAR\u03b3,":[106],"SLC30A8,":[107],"TCF7L2,":[108],"TFAP2B,":[109],"TP53INP1,":[110],"WFS1)":[112],"replicated":[115],"in":[116,130,246],"populations.":[118,248],"To":[119],"our":[120],"knowledge,":[121],"large-scale":[122],"population-":[123],"or":[124],"family-based":[125],"studies":[127,138,165],"are":[128],"non-existent":[129],"region.":[132],"Recently,":[133],"we":[134],"conducted":[135],"genome-wide":[136],"on":[139,198,223],"individuals":[141],"from":[142],"Kuwait":[143],"delineate":[145],"quantitative":[150],"traits":[151,245],"associated":[152,240],"anthropometry,":[154],"lipid":[155],"profile,":[156],"insulin":[157],"resistance,":[158],"blood":[160],"pressure":[161],"levels.":[162],"Although":[163],"these":[164],"led":[166],"identification":[169],"novel":[171],"recessive":[172,199],"variants,":[173],"they":[174,182],"failed":[175],"reproduce":[177],"loci.":[180],"However,":[181],"provided":[183],"insights":[184],"into":[185],"architecture":[188],"applicability":[193],"models":[196],"based":[197],"mode":[200],"inheritance,":[202],"presence":[204],"signatures":[207],"inbreeding":[209],"due":[210],"practice":[213],"consanguinity,":[215],"pleiotropic":[218],"rare":[221],"disorders":[222],"complex":[224],"This":[227],"perspective":[228],"presents":[229],"analysis":[230],"strategies":[231],"study":[233],"designs":[234],"identifying":[236],"variants":[239],"diabetes":[242],"related":[244]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":5},{"year":2019,"cited_by_count":3}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2019-02-21T00:00:00"}