{"id":"https://openalex.org/W2914835824","doi":null,"title":"Family relationships and health locus of control as covariables in the evolution of major depressive disorder.","display_name":"Family relationships and health locus of control as covariables in the evolution of major depressive disorder.","publication_year":2019,"publication_date":"2019-09-01","ids":{"openalex":"https://openalex.org/W2914835824","mag":"2914835824","pmid":"https://pubmed.ncbi.nlm.nih.gov/31488733"},"language":"en","primary_location":{"id":"pmid:31488733","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31488733","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychiatria Danubina","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/2078.1/219332","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5022155690","display_name":"Nicolas Zdanowicz","orcid":"https://orcid.org/0000-0001-9838-3262","observed_orcids":["https://orcid.org/0000-0001-9838-3262"]},"institutions":[{"id":"https://openalex.org/I95674353","display_name":"UCLouvain","ror":"https://ror.org/02495e989","country_code":"BE","type":"education","lineage":["https://openalex.org/I95674353"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Nicolas Zdanowicz","raw_affiliation_strings":["Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, 5530 Yvoir, Belgium, Nicolas.zdanowicz@uclouvain.be","Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, 5530 Yvoir, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, 5530 Yvoir, Belgium, Nicolas.zdanowicz@uclouvain.be","institution_ids":["https://openalex.org/I95674353"]},{"raw_affiliation_string":"Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, 5530 Yvoir, Belgium","institution_ids":["https://openalex.org/I95674353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054614169","display_name":"Christine Reynaert","orcid":"https://orcid.org/0000-0002-0866-8094","observed_orcids":["https://orcid.org/0000-0002-0866-8094"]},"institutions":[{"id":"https://openalex.org/I95674353","display_name":"UCLouvain","ror":"https://ror.org/02495e989","country_code":"BE","type":"education","lineage":["https://openalex.org/I95674353"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Christine Reynaert","raw_affiliation_strings":["Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium","institution_ids":["https://openalex.org/I95674353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030597933","display_name":"Denis Jaques","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95674353","display_name":"UCLouvain","ror":"https://ror.org/02495e989","country_code":"BE","type":"education","lineage":["https://openalex.org/I95674353"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Denis Jaques","raw_affiliation_strings":["Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium","institution_ids":["https://openalex.org/I95674353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005509740","display_name":"Brice Lepi\u00e8ce","orcid":"https://orcid.org/0000-0002-4780-5610","observed_orcids":["https://orcid.org/0000-0002-4780-5610"]},"institutions":[{"id":"https://openalex.org/I95674353","display_name":"UCLouvain","ror":"https://ror.org/02495e989","country_code":"BE","type":"education","lineage":["https://openalex.org/I95674353"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Brice Lepiece","raw_affiliation_strings":["Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium","institution_ids":["https://openalex.org/I95674353"]}]},{"author_position":"last","author":{"id":null,"display_name":"Thomas Dubois","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I95674353","display_name":"UCLouvain","ror":"https://ror.org/02495e989","country_code":"BE","type":"education","lineage":["https://openalex.org/I95674353"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"Thomas Dubois","raw_affiliation_strings":["Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Catholique de Louvain, Psychosomatics Unit, Mont-Godinne University Hospital, Yvoir, Belgium","institution_ids":["https://openalex.org/I95674353"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I95674353"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"31","issue":"Suppl 3","first_page":"237","last_page":"241"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.8246999979019165,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.8246999979019165,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10853","display_name":"Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes","score":0.08399999886751175,"subfield":{"id":"https://openalex.org/subfields/3205","display_name":"Experimental and Cognitive Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T10272","display_name":"Mental Health Treatment and Access","score":0.01549999974668026,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/major-depressive-disorder","display_name":"major depressive disorder","score":1.0},{"id":"https://openalex.org/keywords/health-locus-of-control","display_name":"health locus of control","score":0.984000027179718},{"id":"https://openalex.org/keywords/family-relationships","display_name":"family relationships","score":0.996999979019165},{"id":"https://openalex.org/keywords/personality-traits","display_name":"personality traits","score":0.9419999718666077},{"id":"https://openalex.org/keywords/antidepressant-response","display_name":"antidepressant response","score":0.6520000100135803},{"id":"https://openalex.org/keywords/noradrenergic-antidepressants","display_name":"noradrenergic antidepressants","score":0.9459999799728394},{"id":"https://openalex.org/keywords/serotonergic-antidepressants","display_name":"serotonergic antidepressants","score":0.9980000257492065},{"id":"https://openalex.org/keywords/aspirin","display_name":"aspirin","score":0.9750000238418579},{"id":"https://openalex.org/keywords/physical-health","display_name":"physical health","score":0.5960000157356262},{"id":"https://openalex.org/keywords/family-cohesion","display_name":"family cohesion","score":0.48100000619888306}],"concepts":[{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.666681170463562},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.6437709927558899},{"id":"https://openalex.org/C170798268","wikidata":"https://www.wikidata.org/wiki/Q534589","display_name":"Locus of control","level":2,"score":0.5781572461128235},{"id":"https://openalex.org/C187288502","wikidata":"https://www.wikidata.org/wiki/Q641118","display_name":"Personality","level":2,"score":0.5404859781265259},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.5384023785591125},{"id":"https://openalex.org/C2865642","wikidata":"https://www.wikidata.org/wiki/Q378132","display_name":"Big Five personality traits","level":3,"score":0.4558003544807434},{"id":"https://openalex.org/C53059260","wikidata":"https://www.wikidata.org/wiki/Q374758","display_name":"Multilevel model","level":2,"score":0.4296179413795471},{"id":"https://openalex.org/C2779631380","wikidata":"https://www.wikidata.org/wiki/Q813655","display_name":"Beck Depression Inventory","level":3,"score":0.4241794943809509},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.35288792848587036},{"id":"https://openalex.org/C138496976","wikidata":"https://www.wikidata.org/wiki/Q175002","display_name":"Developmental psychology","level":1,"score":0.23310980200767517},{"id":"https://openalex.org/C2780733359","wikidata":"https://www.wikidata.org/wiki/Q331769","display_name":"Mood","level":2,"score":0.11119517683982849},{"id":"https://openalex.org/C77805123","wikidata":"https://www.wikidata.org/wiki/Q161272","display_name":"Social psychology","level":1,"score":0.10094967484474182},{"id":"https://openalex.org/C558461103","wikidata":"https://www.wikidata.org/wiki/Q154430","display_name":"Anxiety","level":2,"score":0.0},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.0},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000928","descriptor_name":"Antidepressive Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Major Depressive Disorder","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003865","descriptor_name":"Major Depressive Disorder","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":true},{"descriptor_ui":"D005195","descriptor_name":"Family Relations","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007389","descriptor_name":"Internal-External Control","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D011569","descriptor_name":"Psychiatric Status Rating Scales","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:31488733","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31488733","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Psychiatria Danubina","raw_type":"Journal Article"},{"id":"pmh:oai:dial.uclouvain.be:boreal:219332","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2078.1/219332","pdf_url":null,"source":{"id":"https://openalex.org/S4306401902","display_name":"Digital Access to Libraries (Universit\u00e9 catholique de Louvain (UCL), l'Universit\u00e9 de Namur (UNamur) and the Universit\u00e9 Saint-Louis (USL-B))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I95674353","host_organization_name":"UCLouvain","host_organization_lineage":["https://openalex.org/I95674353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Psychiatria Danubina, Vol. 31, no. Suppl 3, p. 237-241 (2019)","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:2914835824","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/31488733","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:dial.uclouvain.be:boreal:219332","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/2078.1/219332","pdf_url":null,"source":{"id":"https://openalex.org/S4306401902","display_name":"Digital Access to Libraries (Universit\u00e9 catholique de Louvain (UCL), l'Universit\u00e9 de Namur (UNamur) and the Universit\u00e9 Saint-Louis (USL-B))","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I95674353","host_organization_name":"UCLouvain","host_organization_lineage":["https://openalex.org/I95674353"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Psychiatria Danubina, Vol. 31, no. Suppl 3, p. 237-241 (2019)","raw_type":"info:eu-repo/semantics/article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":16,"referenced_works":["https://openalex.org/W1933826074","https://openalex.org/W1977192185","https://openalex.org/W1981785586","https://openalex.org/W1986880623","https://openalex.org/W1987008817","https://openalex.org/W1988207403","https://openalex.org/W2006757317","https://openalex.org/W2015114767","https://openalex.org/W2021111372","https://openalex.org/W2099161888","https://openalex.org/W2115256221","https://openalex.org/W2141292956","https://openalex.org/W2172151487","https://openalex.org/W2326556724","https://openalex.org/W2560565629","https://openalex.org/W2788337440"],"related_works":["https://openalex.org/W4200628786","https://openalex.org/W3163807505","https://openalex.org/W7065875322","https://openalex.org/W3029571291","https://openalex.org/W2366994644","https://openalex.org/W2020974259","https://openalex.org/W2361808715","https://openalex.org/W2010824604","https://openalex.org/W2987974311","https://openalex.org/W2382289199"],"abstract_inverted_index":{"BACKGROUND:":[0],"In":[1,33],"a":[2,79,178,225],"two-year":[3],"study,":[4,91],"we":[5,36,254],"compared":[6],"the":[7,17,38,41,52,69,87,90,102,110,116,125,132,137,144,153,160,169,187,213,217,230,261],"efficacy":[8],"of":[9,19,40,44,54,81,89,106,152,155,163,173,196,200,247],"noradrenergic":[10],"and":[11,15,48,96,115,119,143,191,198,233],"serotonergic":[12],"antidepressants":[13],"with":[14,61,78],"without":[16],"addition":[18],"100":[20],"mg":[21],"acetylsalicylic":[22],"acid":[23],"(ASA)":[24],"in":[25,76,168,212,227],"subjects":[26,84,127],"suffering":[27],"from":[28,186],"major":[29],"depressive":[30],"disorder":[31],"(MDD).":[32],"this":[34],"article":[35],"examine":[37],"influence":[39,256],"health":[42,158],"locus":[43],"control,":[45],"family":[46,239],"relationships":[47],"personality":[49,243],"traits":[50],"on":[51,229],"progress":[53],"MDD.":[55],"SUBJECTS":[56],"AND":[57],"METHODS:":[58],"40":[59],"people":[60],"MDD":[62,170,214],"(MDD":[63],"group)":[64],"were":[65,74,94,98,128],"randomly":[66],"assigned":[67],"to":[68,100,259,263],"different":[70],"treatment":[71,223],"groups.":[72],"They":[73],"followed":[75],"parallel":[77],"group":[80,215],"20":[82],"'healthy'":[83],"(HG).":[85],"At":[86],"beginning":[88],"sociodemographic":[92],"data":[93],"collected,":[95],"patients":[97],"asked":[99],"complete":[101],"Multidimensional":[103],"Health":[104,140],"Locus":[105],"Control":[107],"(MHLC)":[108],"scale,":[109],"NEO":[111],"Five-Factor":[112],"Inventory":[113],"(NEO-FFI),":[114],"Family":[117],"Adaptation":[118],"Cohesion":[120],"Scale":[121,135],"(FACES":[122],"III).":[123],"During":[124],"study":[126],"regularly":[129],"assessed":[130],"using":[131],"Hamilton":[133],"Depression":[134],"(HDS),":[136],"Short":[138],"Form":[139],"Survey":[141],"(SF-12)":[142],"Clinical":[145],"Global":[146],"Impression":[147],"scale":[148],"(CGI).":[149],"RESULTS:":[150],"Regardless":[151],"type":[154],"treatment,":[156],"physical":[157],"is":[159,175,203,224],"best":[161],"predictor":[162],"variation":[164],"at":[165],"two":[166],"years":[167],"group;":[171],"45%":[172],"variance":[174,202],"explained":[176],"by":[177],"linear":[179],"regression":[180],"model":[181],"that":[182],"includes":[183],"three":[184],"variables":[185,207],"MHLC,":[188],"FACES":[189],"III":[190],"NEO-FFI":[192],"scales.":[193],"Similarly,":[194],"40%":[195],"CGI":[197,232],"24%":[199],"HDS":[201],"predicted.":[204],"These":[205],"explanatory":[206],"are":[208,244],"statistically":[209],"less":[210],"powerful":[211],"than":[216],"HG":[218],"group.":[219],"CONCLUSION:":[220],"While":[221],"drug":[222],"determinant":[226],"changes":[228],"HDS,":[231],"SF12":[234],"scales,":[235],"factors":[236],"such":[237],"as":[238],"relationships,":[240],"MHLC":[241],"or":[242],"important":[245],"covariates":[246,258],"these":[248,257],"changes.":[249],"The":[250],"question":[251],"remains":[252],"whether":[253],"can":[255],"improve":[260],"response":[262],"antidepressants.":[264]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-02-21T00:00:00"}