{"id":"https://openalex.org/W2914580449","doi":"https://doi.org/10.1016/j.jaci.2018.12.901","title":"Effect of CysLTR1 blockade on allergen challenge induced CD49d expressing neutrophil recruitment to the nasal lavage","display_name":"Effect of CysLTR1 blockade on allergen challenge induced CD49d expressing neutrophil recruitment to the nasal lavage","publication_year":2019,"publication_date":"2019-02-01","ids":{"openalex":"https://openalex.org/W2914580449","doi":"https://doi.org/10.1016/j.jaci.2018.12.901","mag":"2914580449"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaci.2018.12.901","doi":"https://doi.org/10.1016/j.jaci.2018.12.901","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2018.12.901","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5038175283","display_name":"Lisa M. Martorano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1314135232","display_name":"Nationwide Children's Hospital","ror":"https://ror.org/003rfsp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1314135232"]},{"id":"https://openalex.org/I2802841970","display_name":"The Ohio State University Wexner Medical Center","ror":"https://ror.org/00c01js51","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I2802841970"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lisa M. Martorano","raw_affiliation_strings":["Ohio State University Wexner Medical Center and Nationwide Children's Hospital, Columbus, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Ohio State University Wexner Medical Center and Nationwide Children's Hospital, Columbus, OH","institution_ids":["https://openalex.org/I1314135232","https://openalex.org/I2802841970","https://openalex.org/I52357470"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5064876164","display_name":"Syed-Rehan A. Hussain","orcid":"https://orcid.org/0000-0002-2530-7303","observed_orcids":["https://orcid.org/0000-0002-2530-7303"]},"institutions":[{"id":"https://openalex.org/I1314135232","display_name":"Nationwide Children's Hospital","ror":"https://ror.org/003rfsp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1314135232"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Syed-Rehan A. Hussain","raw_affiliation_strings":["Nationwide Children's Hospital, Columbus, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nationwide Children's Hospital, Columbus, OH","institution_ids":["https://openalex.org/I1314135232"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045486522","display_name":"Melinda G. Smith","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1314135232","display_name":"Nationwide Children's Hospital","ror":"https://ror.org/003rfsp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1314135232"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Melinda Smith","raw_affiliation_strings":["Nationwide Children's Hospital, Columbus, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nationwide Children's Hospital, Columbus, OH","institution_ids":["https://openalex.org/I1314135232"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060117787","display_name":"Michelle M. Rohlfing","orcid":"https://orcid.org/0009-0007-8354-8811","observed_orcids":["https://orcid.org/0009-0007-8354-8811"]},"institutions":[{"id":"https://openalex.org/I1314135232","display_name":"Nationwide Children's Hospital","ror":"https://ror.org/003rfsp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1314135232"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michelle Rohlfing","raw_affiliation_strings":["Research Institute at Nationwide Children's Hospital, Columbus, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute at Nationwide Children's Hospital, Columbus, OH","institution_ids":["https://openalex.org/I1314135232"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086629703","display_name":"Jennifer L. Santoro","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1314135232","display_name":"Nationwide Children's Hospital","ror":"https://ror.org/003rfsp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1314135232"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jennifer L. Santoro","raw_affiliation_strings":["Research Institute at Nationwide Children's Hospital, Columbus, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research Institute at Nationwide Children's Hospital, Columbus, OH","institution_ids":["https://openalex.org/I1314135232"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043556111","display_name":"Mitchell H. Grayson","orcid":"https://orcid.org/0000-0002-4673-2122","observed_orcids":["https://orcid.org/0000-0002-4673-2122"]},"institutions":[{"id":"https://openalex.org/I1314135232","display_name":"Nationwide Children's Hospital","ror":"https://ror.org/003rfsp33","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1314135232"]},{"id":"https://openalex.org/I52357470","display_name":"The Ohio State University","ror":"https://ror.org/00rs6vg23","country_code":"US","type":"education","lineage":["https://openalex.org/I52357470"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mitchell H. Grayson","raw_affiliation_strings":["Nationwide Children's Hospital / The Ohio State University, Columbus, OH"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nationwide Children's Hospital / The Ohio State University, Columbus, OH","institution_ids":["https://openalex.org/I1314135232","https://openalex.org/I52357470"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.01886239,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"143","issue":"2","first_page":"AB295","last_page":"AB295"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.7139000296592712,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.22499999403953552,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine","score":0.014499999582767487,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cysteinyl-leukotriene-receptor-1","display_name":"cysteinyl leukotriene receptor 1","score":0.9459999799728394},{"id":"https://openalex.org/keywords/neutrophil-recruitment","display_name":"neutrophil recruitment","score":0.8880000114440918},{"id":"https://openalex.org/keywords/nasal-irrigation","display_name":"nasal irrigation","score":0.8880000114440918},{"id":"https://openalex.org/keywords/allergen-challenge","display_name":"allergen challenge","score":0.984000027179718},{"id":"https://openalex.org/keywords/cold-symptoms","display_name":"cold symptoms","score":0.5989999771118164},{"id":"https://openalex.org/keywords/neutrophil-apoptosis","display_name":"neutrophil apoptosis","score":0.953000009059906},{"id":"https://openalex.org/keywords/leukotriene-receptor-antagonists","display_name":"leukotriene receptor antagonists","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C2776322731","wikidata":"https://www.wikidata.org/wiki/Q417767","display_name":"Montelukast","level":3,"score":0.793921947479248},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7366605997085571},{"id":"https://openalex.org/C2909814679","wikidata":"https://www.wikidata.org/wiki/Q1425813","display_name":"Nasal Lavage","level":3,"score":0.6946559548377991},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.6514882445335388},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.5858656167984009},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.36175310611724854},{"id":"https://openalex.org/C2776042228","wikidata":"https://www.wikidata.org/wiki/Q35869","display_name":"Asthma","level":2,"score":0.27381497621536255},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.1470758616924286},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1097474992275238},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jaci.2018.12.901","doi":"https://doi.org/10.1016/j.jaci.2018.12.901","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2018.12.901","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9763000011444092,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2972008916","https://openalex.org/W2330178545","https://openalex.org/W2193154020","https://openalex.org/W2950469893","https://openalex.org/W1979670373","https://openalex.org/W2301037762","https://openalex.org/W3025529671","https://openalex.org/W2114855242","https://openalex.org/W2038059150","https://openalex.org/W2038510228"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-02-21T00:00:00"}