{"id":"https://openalex.org/W2914424516","doi":"https://doi.org/10.17219/acem/94065","title":"Matrix metalloproteinase-3 levels in relation to disease activity and radiological progression in rheumatoid arthritis","display_name":"Matrix metalloproteinase-3 levels in relation to disease activity and radiological progression in rheumatoid arthritis","publication_year":2019,"publication_date":"2019-02-08","ids":{"openalex":"https://openalex.org/W2914424516","doi":"https://doi.org/10.17219/acem/94065","mag":"2914424516","pmid":"https://pubmed.ncbi.nlm.nih.gov/30740946"},"language":"en","primary_location":{"id":"doi:10.17219/acem/94065","doi":"https://doi.org/10.17219/acem/94065","is_oa":true,"landing_page_url":"https://doi.org/10.17219/acem/94065","pdf_url":"http://www.advances.umed.wroc.pl/pdf/2019/28/5/665.pdf","source":{"id":"https://openalex.org/S948795172","display_name":"Advances in Clinical and Experimental Medicine","issn_l":"1899-5276","issn":["1899-5276","2451-2680"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4353108602","host_organization_name":"Wroclaw Medical University","host_organization_lineage":["https://openalex.org/P4353108602"],"host_organization_lineage_names":["Wroclaw Medical University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Clinical and Experimental Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"http://www.advances.umed.wroc.pl/pdf/2019/28/5/665.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056718646","display_name":"T\u00fcrkan Tuncer","orcid":"https://orcid.org/0000-0001-8085-7562","observed_orcids":["https://orcid.org/0000-0001-8085-7562"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Turkan Tuncer","raw_affiliation_strings":["Department of Physical Medicine and Rehabilitation, Faculty of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey","institution_ids":["https://openalex.org/I143396566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113829698","display_name":"Arzu Kaya","orcid":"https://orcid.org/0000-0002-8824-4266","observed_orcids":["https://orcid.org/0000-0002-8824-4266"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Arzu Kaya","raw_affiliation_strings":["Department of Physical Medicine and Rehabilitation, Faculty of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey","institution_ids":["https://openalex.org/I143396566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033896269","display_name":"Arif G\u00fclkesen","orcid":"https://orcid.org/0000-0002-3008-7333","observed_orcids":["https://orcid.org/0000-0002-3008-7333"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Arif Gulkesen","raw_affiliation_strings":["Department of Physical Medicine and Rehabilitation, Faculty of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey","institution_ids":["https://openalex.org/I143396566"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058767550","display_name":"G\u00fcl Ayden Kal","orcid":"https://orcid.org/0000-0002-6093-7888","observed_orcids":["https://orcid.org/0000-0002-6093-7888"]},"institutions":[{"id":"https://openalex.org/I4210144819","display_name":"Elaz\u0131\u011f E\u011fitim ve Ara\u015ft\u0131rma Hastanesi","ror":"https://ror.org/03dwvx056","country_code":"TR","type":"healthcare","lineage":["https://openalex.org/I4210144819"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Gul Ayden Kal","raw_affiliation_strings":["Department of Physical Medicine and Rehabilitation, Elaz\u0131\u011f Training and Research Hospital, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Elaz\u0131\u011f Training and Research Hospital, Turkey","institution_ids":["https://openalex.org/I4210144819"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011269737","display_name":"Dilara Kaman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"Dilara Kaman","raw_affiliation_strings":["Department of Biochemistry and Clinical Biochemistry School of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biochemistry and Clinical Biochemistry School of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey","institution_ids":["https://openalex.org/I143396566"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5021225545","display_name":"G\u00fcrkan Akg\u00f6l","orcid":"https://orcid.org/0000-0003-1948-6410","observed_orcids":["https://orcid.org/0000-0003-1948-6410"]},"institutions":[{"id":"https://openalex.org/I143396566","display_name":"F\u0131rat University","ror":"https://ror.org/05teb7b63","country_code":"TR","type":"education","lineage":["https://openalex.org/I143396566"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"Gurkan Akgol","raw_affiliation_strings":["Department of Physical Medicine and Rehabilitation, Faculty of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Physical Medicine and Rehabilitation, Faculty of Medicine, F\u0131rat University, Elaz\u0131\u011f, Turkey","institution_ids":["https://openalex.org/I143396566"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5021225545"],"corresponding_institution_ids":["https://openalex.org/I143396566"],"apc_list":{"value":700,"currency":"EUR","value_usd":754},"apc_paid":{"value":700,"currency":"EUR","value_usd":754},"fwci":2.8785,"has_fulltext":true,"cited_by_count":36,"citation_normalized_percentile":{"value":0.90474641,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":91,"max":99},"biblio":{"volume":"28","issue":"5","first_page":"665","last_page":"670"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10200","display_name":"Rheumatoid Arthritis Research and Therapies","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11616","display_name":"Autoimmune and Inflammatory Disorders Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rheumatoid-arthritis","display_name":"rheumatoid arthritis","score":0.9940000176429749},{"id":"https://openalex.org/keywords/matrix-metalloproteinase-3","display_name":"matrix metalloproteinase-3","score":1.0},{"id":"https://openalex.org/keywords/serum-biomarkers","display_name":"serum biomarkers","score":0.9139999747276306},{"id":"https://openalex.org/keywords/disease-activity","display_name":"disease activity","score":0.9980000257492065},{"id":"https://openalex.org/keywords/radiographic-progression","display_name":"radiographic progression","score":0.8059999942779541},{"id":"https://openalex.org/keywords/structural-damage","display_name":"structural damage","score":0.7889999747276306},{"id":"https://openalex.org/keywords/erosion","display_name":"erosion","score":0.7620000243186951},{"id":"https://openalex.org/keywords/das28","display_name":"DAS28","score":0.753000020980835},{"id":"https://openalex.org/keywords/early-rheumatoid-arthritis","display_name":"early rheumatoid arthritis","score":0.8050000071525574},{"id":"https://openalex.org/keywords/disease-surveillance","display_name":"disease surveillance","score":0.5009999871253967}],"concepts":[{"id":"https://openalex.org/C2777575956","wikidata":"https://www.wikidata.org/wiki/Q187255","display_name":"Rheumatoid arthritis","level":2,"score":0.7779021859169006},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6912785768508911},{"id":"https://openalex.org/C109523444","wikidata":"https://www.wikidata.org/wiki/Q424216","display_name":"Matrix metalloproteinase","level":2,"score":0.6668163537979126},{"id":"https://openalex.org/C2910007452","wikidata":"https://www.wikidata.org/wiki/Q21114943","display_name":"Matrix Metalloproteinase 3","level":3,"score":0.6387203931808472},{"id":"https://openalex.org/C190892606","wikidata":"https://www.wikidata.org/wiki/Q3512464","display_name":"Radiological weapon","level":2,"score":0.6367056965827942},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4347427487373352},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3716059625148773},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.24737417697906494}],"mesh":[{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D001172","descriptor_name":"Arthritis, Rheumatoid","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D001799","descriptor_name":"Blood Sedimentation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004797","descriptor_name":"Enzyme-Linked Immunosorbent Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011237","descriptor_name":"Predictive Value of Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011859","descriptor_name":"Radiography","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D012217","descriptor_name":"Rheumatoid Factor","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015415","descriptor_name":"Biomarkers","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D016022","descriptor_name":"Case-Control Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018450","descriptor_name":"Disease Progression","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019278","descriptor_name":"Matrix Metalloproteinase 3","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D019278","descriptor_name":"Matrix Metalloproteinase 3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.17219/acem/94065","doi":"https://doi.org/10.17219/acem/94065","is_oa":true,"landing_page_url":"https://doi.org/10.17219/acem/94065","pdf_url":"http://www.advances.umed.wroc.pl/pdf/2019/28/5/665.pdf","source":{"id":"https://openalex.org/S948795172","display_name":"Advances in Clinical and Experimental Medicine","issn_l":"1899-5276","issn":["1899-5276","2451-2680"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4353108602","host_organization_name":"Wroclaw Medical University","host_organization_lineage":["https://openalex.org/P4353108602"],"host_organization_lineage_names":["Wroclaw Medical University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Clinical and Experimental Medicine","raw_type":"journal-article"},{"id":"pmid:30740946","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30740946","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in clinical and experimental medicine : official organ Wroclaw Medical University","raw_type":"Journal Article"},{"id":"pmh:oai:openaccess.firat.edu.tr:11508/52884","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11508/52884","pdf_url":null,"source":{"id":"https://openalex.org/S4377196733","display_name":"DSpace - FIRAT (F\u0131rat University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I143396566","host_organization_name":"F\u0131rat University","host_organization_lineage":["https://openalex.org/I143396566"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"Article"}],"best_oa_location":{"id":"doi:10.17219/acem/94065","doi":"https://doi.org/10.17219/acem/94065","is_oa":true,"landing_page_url":"https://doi.org/10.17219/acem/94065","pdf_url":"http://www.advances.umed.wroc.pl/pdf/2019/28/5/665.pdf","source":{"id":"https://openalex.org/S948795172","display_name":"Advances in Clinical and Experimental Medicine","issn_l":"1899-5276","issn":["1899-5276","2451-2680"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-70","russia-white-list-2","vabb-shw"],"host_organization":"https://openalex.org/P4353108602","host_organization_name":"Wroclaw Medical University","host_organization_lineage":["https://openalex.org/P4353108602"],"host_organization_lineage_names":["Wroclaw Medical University"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Clinical and Experimental Medicine","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9940000176429749,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2914424516.pdf","grobid_xml":"https://content.openalex.org/works/W2914424516.grobid-xml"},"referenced_works_count":36,"referenced_works":["https://openalex.org/W8012605","https://openalex.org/W184648558","https://openalex.org/W1792090112","https://openalex.org/W1969061349","https://openalex.org/W2010544154","https://openalex.org/W2014351030","https://openalex.org/W2022941966","https://openalex.org/W2035536661","https://openalex.org/W2036272657","https://openalex.org/W2051905494","https://openalex.org/W2074775112","https://openalex.org/W2080731122","https://openalex.org/W2106670287","https://openalex.org/W2110177517","https://openalex.org/W2112482146","https://openalex.org/W2115119680","https://openalex.org/W2115608334","https://openalex.org/W2117080736","https://openalex.org/W2121158586","https://openalex.org/W2124502604","https://openalex.org/W2128049766","https://openalex.org/W2136007246","https://openalex.org/W2140600513","https://openalex.org/W2142497985","https://openalex.org/W2142677189","https://openalex.org/W2143065147","https://openalex.org/W2148078801","https://openalex.org/W2152348310","https://openalex.org/W2159700028","https://openalex.org/W2166453502","https://openalex.org/W2167795312","https://openalex.org/W2168125040","https://openalex.org/W2181580074","https://openalex.org/W2403282231","https://openalex.org/W4231972505","https://openalex.org/W4308769923"],"related_works":["https://openalex.org/W2291331193","https://openalex.org/W2609602574","https://openalex.org/W2531048072","https://openalex.org/W2365874621","https://openalex.org/W2075408986","https://openalex.org/W2411150599","https://openalex.org/W2280934856","https://openalex.org/W2014351030","https://openalex.org/W607569205","https://openalex.org/W2367631088"],"abstract_inverted_index":{"BACKGROUND:":[0],"Rheumatoid":[1],"arthritis":[2],"(RA)":[3],"is":[4],"a":[5,98,113],"chronic":[6],"inflammatory":[7],"and":[8,19,38,59,62,80,142,159,195,210,219,264,316],"systemic":[9],"disease":[10,110,121,134,199,233,248,319],"of":[11,35,48,133,198,228,243,313],"unknown":[12],"etiology":[13],"that":[14,293],"primarily":[15],"affects":[16],"synovial":[17],"joints":[18],"involves":[20],"progressive":[21],"destruction":[22,34],"around":[23],"the":[24,29,33,90,124,154,213,244,272,310,314],"joints.":[25],"Inflammation":[26],"starting":[27],"in":[28,65,131,175,183,261,309],"joint":[30],"synovium":[31],"causes":[32],"cartilage,":[36],"bone":[37],"other":[39],"adjacent":[40],"tissues":[41],"with":[42,67,78,97,119,177,193,231,246,282],"pannus":[43],"formation.":[44],"OBJECTIVES:":[45],"The":[46,73,224],"aim":[47],"this":[49],"study":[50,74],"was":[51,151],"to":[52,237,258,317],"evaluate":[53],"serum":[54,225,283,294],"matrix":[55],"metalloproteinase-3":[56],"(MMP-3)":[57],"levels":[58,86,174,190,227,255,285,296],"their":[60],"clinical":[61,196],"radiological":[63],"significance":[64],"patients":[66,77,118,125,176,230,245,267],"rheumatoid":[68,216],"arthritis.":[69],"MATERIAL":[70],"AND":[71],"METHODS:":[72],"included":[75],"59":[76],"RA":[79,137,144,178,229,266],"30":[81],"healthy":[82],"controls.":[83],"Serum":[84,172,188],"MMP-3":[85,173,189,226,254,284,295],"were":[87,105,126,165,179,191,215,235,256],"measured":[88],"using":[89,153,167],"enzyme-linked":[91],"immunosorbent":[92],"assay":[93],"(ELISA)":[94],"method.":[95],"Patients":[96],"Disease":[99],"Activity":[100],"Score":[101],"28":[102],"(DAS28)":[103],"\u22643.2":[104],"categorized":[106],"as":[107,300,307],"having":[108],"lower":[109],"activity,":[111,200],"while":[112],"DAS28":[114],"score":[115],">3.2":[116],"indicated":[117],"moderate/high":[120,232],"activity.":[122,320],"Additionally,":[123,271],"divided":[127],"into":[128],"2":[129],"groups":[130],"terms":[132],"duration:":[135],"early":[136,265,311],"(disease":[138,145],"duration":[139,146],"\u22642":[140],"years)":[141],"established":[143,263],"\u22652":[147],"years).":[148],"Functional":[149],"disability":[150],"evaluated":[152],"Health":[155,161],"Assessment":[156],"Questionnaire":[157],"(HAQ)":[158],"Nottingham":[160],"Profile":[162],"(NHP).":[163],"Radiographs":[164],"scored":[166],"modified":[168,273],"Larsen":[169,274],"scoring.":[170],"RESULTS:":[171],"significantly":[180,239,281],"higher":[181,240],"than":[182,241],"controls":[184],"(p":[185,250,268,286],"=":[186,269,287],"0.001).":[187,252,288],"correlated":[192,280],"laboratory":[194],"parameters":[197],"including":[201],"erythrocyte":[202],"sedimentation":[203],"rate":[204],"(ESR),":[205],"C-reactive":[206],"protein":[207],"(CRP),":[208],"DAS28,":[209],"HAQ":[211],"score;":[212],"exceptions":[214],"factor":[217],"(RF)":[218],"cyclic":[220],"citrullinated":[221],"peptides":[222],"(CCP).":[223],"activity":[234,249],"found":[236,257],"be":[238,259,298],"those":[242],"low":[247],"<":[251],"However,":[253],"similar":[260],"both":[262],"0.927).":[270],"scores,":[275],"which":[276],"indicate":[277,292],"structural":[278,304],"damage,":[279],"CONCLUSIONS:":[289],"These":[290],"results":[291],"may":[297],"used":[299],"an":[301],"indicator":[302],"for":[303],"damage":[305],"such":[306],"erosions":[308],"stages":[312],"disease,":[315],"monitor":[318]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-02-21T00:00:00"}