{"id":"https://openalex.org/W2914169043","doi":"https://doi.org/10.1681/asn.2017101138","title":"T Cells Play a Causal Role in Diastolic Dysfunction during Uremic Cardiomyopathy","display_name":"T Cells Play a Causal Role in Diastolic Dysfunction during Uremic Cardiomyopathy","publication_year":2019,"publication_date":"2019-02-06","ids":{"openalex":"https://openalex.org/W2914169043","doi":"https://doi.org/10.1681/asn.2017101138","mag":"2914169043","pmid":"https://pubmed.ncbi.nlm.nih.gov/30728178","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6405145"},"language":"en","primary_location":{"id":"doi:10.1681/asn.2017101138","doi":"https://doi.org/10.1681/asn.2017101138","is_oa":false,"landing_page_url":"https://doi.org/10.1681/asn.2017101138","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6405145","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5042275952","display_name":"Pamela D. Winterberg","orcid":"https://orcid.org/0000-0002-8555-2837","observed_orcids":["https://orcid.org/0000-0002-8555-2837"]},"institutions":[{"id":"https://openalex.org/I4210146983","display_name":"Children's Healthcare of Atlanta","ror":"https://ror.org/050fhx250","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210146983"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Pamela D. Winterberg","raw_affiliation_strings":["Children\u2019s Healthcare of Atlanta, Atlanta, Georgia","Division of Pediatric Nephrology, Department of Pediatrics,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children\u2019s Healthcare of Atlanta, Atlanta, Georgia","institution_ids":["https://openalex.org/I4210146983"]},{"raw_affiliation_string":"Division of Pediatric Nephrology, Department of Pediatrics,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036996080","display_name":"Jennifer M. Robertson","orcid":"https://orcid.org/0000-0002-1613-0091","observed_orcids":["https://orcid.org/0000-0002-1613-0091"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jennifer M. Robertson","raw_affiliation_strings":["Emory Transplant Center, Department of Surgery, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory Transplant Center, Department of Surgery, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031104750","display_name":"Michael Scott Kelleman","orcid":"https://orcid.org/0000-0002-4526-6350","observed_orcids":["https://orcid.org/0000-0002-4526-6350"]},"institutions":[{"id":"https://openalex.org/I150468666","display_name":"Emory University","ror":"https://ror.org/03czfpz43","country_code":"US","type":"education","lineage":["https://openalex.org/I150468666"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael S. Kelleman","raw_affiliation_strings":["Biostatistics Core, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biostatistics Core, Department of Pediatrics, Emory University School of Medicine, Atlanta, Georgia; and","institution_ids":["https://openalex.org/I150468666"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5063797083","display_name":"Roshan Punnoose George","orcid":"https://orcid.org/0000-0003-3853-967X","observed_orcids":["https://orcid.org/0000-0003-3853-967X"]},"institutions":[{"id":"https://openalex.org/I4210146983","display_name":"Children's Healthcare of Atlanta","ror":"https://ror.org/050fhx250","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210146983"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roshan P. George","raw_affiliation_strings":["Children\u2019s Healthcare of Atlanta, Atlanta, Georgia","Division of Pediatric Nephrology, Department of Pediatrics,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Children\u2019s Healthcare of Atlanta, Atlanta, Georgia","institution_ids":["https://openalex.org/I4210146983"]},{"raw_affiliation_string":"Division of Pediatric Nephrology, Department of Pediatrics,","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087476769","display_name":"Mandy L. Ford","orcid":"https://orcid.org/0000-0001-6736-4421","observed_orcids":["https://orcid.org/0000-0001-6736-4421"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mandy L. Ford","raw_affiliation_strings":["Emory Transplant Center, Department of Surgery, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Emory Transplant Center, Department of Surgery, and","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5042275952"],"corresponding_institution_ids":["https://openalex.org/I4210146983"],"apc_list":null,"apc_paid":null,"fwci":2.1172,"has_fulltext":false,"cited_by_count":35,"citation_normalized_percentile":{"value":0.88389473,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"30","issue":"3","first_page":"407","last_page":"420"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11962","display_name":"Cardiac Fibrosis and Remodeling","score":0.8041999936103821,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10821","display_name":"Cardiovascular Function and Risk Factors","score":0.16830000281333923,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.009100000374019146,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/uremic-cardiomyopathy","display_name":"uremic cardiomyopathy","score":0.9950000047683716},{"id":"https://openalex.org/keywords/diastolic-dysfunction","display_name":"diastolic dysfunction","score":0.9929999709129333},{"id":"https://openalex.org/keywords/t-cells","display_name":"T cells","score":0.9290000200271606},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.968999981880188},{"id":"https://openalex.org/keywords/t-cell-activation","display_name":"T cell activation","score":0.6470000147819519},{"id":"https://openalex.org/keywords/pd-1","display_name":"PD-1","score":0.9309999942779541},{"id":"https://openalex.org/keywords/cd57","display_name":"CD57","score":0.9919999837875366},{"id":"https://openalex.org/keywords/t-cell-depletion","display_name":"T cell depletion","score":0.8270000219345093},{"id":"https://openalex.org/keywords/anti-cd3-antibody","display_name":"anti-CD3 antibody","score":0.8610000014305115},{"id":"https://openalex.org/keywords/myocardial-strain","display_name":"myocardial strain","score":0.7390000224113464},{"id":"https://openalex.org/keywords/left-ventricular-hypertrophy","display_name":"left ventricular hypertrophy","score":0.9110000133514404},{"id":"https://openalex.org/keywords/t-cell-memory","display_name":"T cell memory","score":0.492000013589859},{"id":"https://openalex.org/keywords/proinflammatory-t-cells","display_name":"proinflammatory T cells","score":0.7120000123977661},{"id":"https://openalex.org/keywords/pediatric-chronic-kidney-disease","display_name":"pediatric chronic kidney disease","score":0.7369999885559082},{"id":"https://openalex.org/keywords/cardiac-inflammation","display_name":"cardiac inflammation","score":0.3179999887943268}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7391902804374695},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.703460156917572},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6792418360710144},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.6417460441589355},{"id":"https://openalex.org/C57900726","wikidata":"https://www.wikidata.org/wiki/Q492905","display_name":"Diastole","level":3,"score":0.5959929823875427},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5616976022720337},{"id":"https://openalex.org/C2776002628","wikidata":"https://www.wikidata.org/wiki/Q1628627","display_name":"Left ventricular hypertrophy","level":3,"score":0.4395096004009247},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.16200172901153564}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1681/asn.2017101138","doi":"https://doi.org/10.1681/asn.2017101138","is_oa":false,"landing_page_url":"https://doi.org/10.1681/asn.2017101138","pdf_url":null,"source":{"id":"https://openalex.org/S115693375","display_name":"Journal of the American Society of Nephrology","issn_l":"1046-6673","issn":["1046-6673","1533-3450"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315620","host_organization_name":"American Society of Nephrology","host_organization_lineage":["https://openalex.org/P4310315620"],"host_organization_lineage_names":["American Society of Nephrology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5990537","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6405145","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6405145","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6405145","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Am Soc Nephrol","raw_type":"Text"},{"id":"pmid:30728178","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30728178","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of the American Society of Nephrology : JASN","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5990537","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6405145","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5274032383","display_name":"Role of T cells in Uremic Cardiomyopathy","funder_award_id":"K08DK111998","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G6594747912","display_name":"Costimulatory and Coinhibitory Receptor Control of Alloreactive T Cell Responses","funder_award_id":"R01AI104699","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7688822183","display_name":"Determinants of T Cell Fate in Transplantation Tolerance","funder_award_id":"R01AI073707","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000900434","display_name":"Atlanta Pediatric Scholars Program","funder_award_id":"K12HD072245","funder_id":"https://openalex.org/F4320337611","funder_display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development"},{"id":"https://openalex.org/G9000906557","display_name":"Emory National Primate Research Center","funder_award_id":"P51OD011132","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"},{"id":"https://openalex.org/F4320337611","display_name":"Eunice Kennedy Shriver National Institute of Child Health and Human Development","ror":"https://ror.org/04byxyr05"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":84,"referenced_works":["https://openalex.org/W1581327117","https://openalex.org/W1668561317","https://openalex.org/W1826064705","https://openalex.org/W1918595551","https://openalex.org/W1929509592","https://openalex.org/W1963606632","https://openalex.org/W1967850399","https://openalex.org/W1968177453","https://openalex.org/W1969840644","https://openalex.org/W1980167042","https://openalex.org/W1982729887","https://openalex.org/W1993316627","https://openalex.org/W1997332439","https://openalex.org/W2005759195","https://openalex.org/W2013013791","https://openalex.org/W2016168268","https://openalex.org/W2017619275","https://openalex.org/W2024825620","https://openalex.org/W2033374607","https://openalex.org/W2033989169","https://openalex.org/W2038523160","https://openalex.org/W2040353461","https://openalex.org/W2041418055","https://openalex.org/W2044042485","https://openalex.org/W2048132371","https://openalex.org/W2048551699","https://openalex.org/W2049685722","https://openalex.org/W2050800512","https://openalex.org/W2051969301","https://openalex.org/W2057499380","https://openalex.org/W2061899137","https://openalex.org/W2063880582","https://openalex.org/W2070309439","https://openalex.org/W2079579094","https://openalex.org/W2083295790","https://openalex.org/W2084029168","https://openalex.org/W2086291447","https://openalex.org/W2089162544","https://openalex.org/W2090451215","https://openalex.org/W2090827352","https://openalex.org/W2095664313","https://openalex.org/W2097400502","https://openalex.org/W2098853737","https://openalex.org/W2099232852","https://openalex.org/W2111039395","https://openalex.org/W2118258530","https://openalex.org/W2123278075","https://openalex.org/W2123716772","https://openalex.org/W2124063441","https://openalex.org/W2124161937","https://openalex.org/W2125487346","https://openalex.org/W2126862979","https://openalex.org/W2129015099","https://openalex.org/W2130852062","https://openalex.org/W2131582262","https://openalex.org/W2133700262","https://openalex.org/W2133808321","https://openalex.org/W2134487085","https://openalex.org/W2135170120","https://openalex.org/W2135511738","https://openalex.org/W2136170412","https://openalex.org/W2141458291","https://openalex.org/W2153626991","https://openalex.org/W2158966732","https://openalex.org/W2164913878","https://openalex.org/W2168863232","https://openalex.org/W2170174785","https://openalex.org/W2273711624","https://openalex.org/W2297219066","https://openalex.org/W2308148842","https://openalex.org/W2325917443","https://openalex.org/W2395130485","https://openalex.org/W2395494967","https://openalex.org/W2396221546","https://openalex.org/W2467035217","https://openalex.org/W2513788684","https://openalex.org/W2592935721","https://openalex.org/W2597217516","https://openalex.org/W2614361772","https://openalex.org/W2724136428","https://openalex.org/W2762433514","https://openalex.org/W3047835824","https://openalex.org/W4320300928","https://openalex.org/W6638381340"],"related_works":["https://openalex.org/W2797300509","https://openalex.org/W7117780924","https://openalex.org/W3182676955","https://openalex.org/W2308148842","https://openalex.org/W4205577512","https://openalex.org/W2791389288","https://openalex.org/W4388966649","https://openalex.org/W6964646634","https://openalex.org/W2964387419","https://openalex.org/W3164256570"],"abstract_inverted_index":{"Significance":[0],"Statement":[1],"Uremic":[2,127],"cardiomyopathy,":[3,128],"which":[4],"features":[5],"left":[6,131],"ventricular":[7,64,132],"hypertrophy,":[8,133],"diastolic":[9,39,60,72,105,134,322,357],"dysfunction,":[10,135],"and":[11,57,62,74,96,136,205,249,268,294,324],"impaired":[12,63,137],"myocardial":[13,75,122,138,325,376],"strain,":[14,65,139],"predicts":[15],"mortality":[16,144],"in":[17,38,81,145,183,275,302,327,364],"patients":[18,146],"with":[19,83,100,147,256,266,277,281,308,340,355],"CKD.":[20,42,125,148,278,304],"In":[21,43,305,338],"this":[22,175],"study,":[23],"the":[24,55,314],"authors":[25],"present":[26],"findings":[27],"supporting":[28],"emerging":[29],"evidence":[30,150],"that":[31,51,80,113,257,371],"T":[32,52,69,88,115,156,166,195,232,247,263,284,311,316,345,369],"cells":[33,53,70,89,157,167,223,248,285,312,346,370],"play":[34],"a":[35,44,152],"causal":[36],"role":[37,154],"dysfunction":[40,61,123],"during":[41,124,158],"mouse":[45],"model":[46],"of":[47,68,87,92,103,192,194,231,258,288,335,344,367],"CKD,":[48,84,341],"they":[49],"demonstrate":[50],"infiltrate":[54],"heart":[56,160,226,251],"lead":[58],"to":[59,118,141,169,189,220,245,373,375],"whereas":[66],"depletion":[67,234,318],"improves":[71],"function":[73,117,252,323,358],"strain.":[76],"They":[77],"also":[78,218],"show":[79],"children":[82,276,339],"increasing":[85,342],"frequency":[86,343],"bearing":[90,286,347],"markers":[91,193,287,349],"sustained":[93],"activation":[94,199,295,348],"(PD-1":[95],"CD57)":[97],"is":[98],"associated":[99,354],"echocardiographic":[101],"indications":[102],"worsening":[104,356],"function.":[106],"Future":[107],"research":[108],"may":[109],"inform":[110],"novel":[111],"therapies":[112],"target":[114],"cell":[116,196,233,264,317],"mitigate":[119],"early":[120],"subclinical":[121],"Background":[126],"characterized":[129],"by":[130,177,200,254],"contributes":[140],"increased":[142],"cardiovascular":[143],"Emerging":[149],"suggests":[151],"pathogenic":[153],"for":[155,212],"chronic":[159],"failure.":[161],"Methods":[162],"To":[163,228],"determine":[164],"whether":[165],"contribute":[168,374],"uremic":[170],"cardiomyopathy":[171],"pathogenesis,":[172],"we":[173,238,261],"modeled":[174],"condition":[176],"inducing":[178],"CKD":[179,203,240,282,309,328,362],"via":[180],"5/6th":[181],"nephrectomy":[182],"mice.":[184],"We":[185],"used":[186,219],"flow":[187],"cytometry":[188,216],"assess":[190],"expression":[191],"memory":[197,289],"or":[198,333],"lymphocytes":[201],"from":[202,225],"mice":[204,241,307,329],"controls,":[206],"as":[207,209,299],"well":[208],"lymphocyte":[210],"capacity":[211],"cytokine":[213],"production.":[214],"Flow":[215],"was":[217,353],"quantify":[221],"immune":[222],"isolated":[224],"tissue.":[227],"test":[229],"effects":[230],"on":[235,271,359],"cardiac":[236],"function,":[237],"gave":[239],"anti-CD3":[242],"antibody":[243],"injections":[244],"deplete":[246],"compared":[250],"(assessed":[253],"echocardiography)":[255],"controls.":[259],"Finally,":[260],"correlated":[262],"phenotypes":[265],"structural":[267],"functional":[269],"measures":[270],"clinically":[272],"acquired":[273],"echocardiograms":[274],"Results":[279],"Mice":[280],"accumulated":[283],"differentiation":[290],"(CD44":[291],"hi":[292],")":[293],"(PD-1,":[296],"KLRG1,":[297],"OX40),":[298],"reported":[300],"previously":[301],"human":[303],"addition,":[306],"showed":[310],"infiltrating":[313],"heart.":[315],"significantly":[319],"improved":[320],"both":[321],"strain":[326],"without":[330],"altering":[331],"hypertension":[332],"degree":[334],"renal":[336],"dysfunction.":[337,377],"PD-1":[350],"and/or":[351],"CD57":[352],"echocardiogram.":[360],"Conclusions":[361],"results":[363],"an":[365],"accumulation":[366],"proinflammatory":[368],"appears":[372]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":6},{"year":2024,"cited_by_count":5},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-02-21T00:00:00"}