{"id":"https://openalex.org/W2913910169","doi":"https://doi.org/10.1104/pp.18.00771","title":"Development of Decreased-Gluten Wheat Enabled by Determination of the Genetic Basis of lys3a Barley","display_name":"Development of Decreased-Gluten Wheat Enabled by Determination of the Genetic Basis of lys3a Barley","publication_year":2019,"publication_date":"2019-01-29","ids":{"openalex":"https://openalex.org/W2913910169","doi":"https://doi.org/10.1104/pp.18.00771","mag":"2913910169","pmid":"https://pubmed.ncbi.nlm.nih.gov/30696748","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6446766"},"language":"en","primary_location":{"id":"doi:10.1104/pp.18.00771","doi":"https://doi.org/10.1104/pp.18.00771","is_oa":true,"landing_page_url":"https://doi.org/10.1104/pp.18.00771","pdf_url":null,"source":{"id":"https://openalex.org/S42294715","display_name":"PLANT PHYSIOLOGY","issn_l":"0032-0889","issn":["0032-0889","1532-2548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Physiology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://doi.org/10.1104/pp.18.00771","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5032282640","display_name":"Charles P. Moehs","orcid":"https://orcid.org/0000-0002-8907-4852","observed_orcids":["https://orcid.org/0000-0002-8907-4852","https://orcid.org/0000-0002-0714-2445"]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Charles P. Moehs","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":"https://orcid.org/0000-0002-8907-4852","affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5003526084","display_name":"William J. Austill","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William J. Austill","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066519817","display_name":"Aaron Holm","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron Holm","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053723468","display_name":"Tao A. G. Large","orcid":"https://orcid.org/0000-0002-0592-3301","observed_orcids":["https://orcid.org/0000-0002-0592-3301"]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tao A.G. Large","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":"https://orcid.org/0000-0002-0592-3301","affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001339132","display_name":"Dayna Loeffler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dayna Loeffler","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5002529879","display_name":"Jessica Mullenberg","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica Mullenberg","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008968750","display_name":"Patrick S. Schnable","orcid":"https://orcid.org/0000-0001-9169-5204","observed_orcids":["https://orcid.org/0000-0001-9169-5204"]},"institutions":[{"id":"https://openalex.org/I173911158","display_name":"Iowa State University","ror":"https://ror.org/04rswrd78","country_code":"US","type":"education","lineage":["https://openalex.org/I173911158"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Patrick S. Schnable","raw_affiliation_strings":["2035B Roy J. Carver Co-Lab, Iowa State University, Ames, Iowa 50011","Data2Bio, 2079 Roy J. Carver Co-Lab, Ames, Iowa 50011","bData2Bio, 2079 Roy J. Carver Co-Lab, Ames, Iowa 50011","c2035B Roy J. Carver Co-Lab, Iowa State University, Ames, Iowa 50011"],"raw_orcid":"https://orcid.org/0000-0001-9169-5204","affiliations":[{"raw_affiliation_string":"2035B Roy J. Carver Co-Lab, Iowa State University, Ames, Iowa 50011","institution_ids":["https://openalex.org/I173911158"]},{"raw_affiliation_string":"Data2Bio, 2079 Roy J. Carver Co-Lab, Ames, Iowa 50011","institution_ids":[]},{"raw_affiliation_string":"bData2Bio, 2079 Roy J. Carver Co-Lab, Ames, Iowa 50011","institution_ids":[]},{"raw_affiliation_string":"c2035B Roy J. Carver Co-Lab, Iowa State University, Ames, Iowa 50011","institution_ids":["https://openalex.org/I173911158"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011631107","display_name":"Wayne S. Skinner","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wayne Skinner","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047542503","display_name":"Jos Van Boxtel","orcid":"https://orcid.org/0000-0002-7483-9170","observed_orcids":["https://orcid.org/0000-0002-7483-9170"]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jos van Boxtel","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040731947","display_name":"Liying Wu","orcid":"https://orcid.org/0000-0001-5277-2078","observed_orcids":["https://orcid.org/0000-0001-5277-2078"]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Liying Wu","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5006140558","display_name":"Cate McGuire","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210159863","display_name":"Arcadia Biosciences (United States)","ror":"https://ror.org/05c1evx63","country_code":"US","type":"company","lineage":["https://openalex.org/I4210159863"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Cate McGuire","raw_affiliation_strings":["Arcadia Biosciences, Davis, California 95618","aArcadia Biosciences, Davis, California 95618"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Arcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]},{"raw_affiliation_string":"aArcadia Biosciences, Davis, California 95618","institution_ids":["https://openalex.org/I4210159863"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3851,"currency":"USD","value_usd":3851},"apc_paid":{"value":3851,"currency":"USD","value_usd":3851},"fwci":4.9745,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.95044005,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":94,"max":99},"biblio":{"volume":"179","issue":"4","first_page":"1692","last_page":"1703"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10733","display_name":"Wheat and Barley Genetics and Pathology","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10733","display_name":"Wheat and Barley Genetics and Pathology","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11348","display_name":"Celiac Disease Research and Management","score":0.0035000001080334187,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12828","display_name":"Plant Genetic and Mutation Studies","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/prolamin","display_name":"prolamin","score":0.746999979019165},{"id":"https://openalex.org/keywords/gluten","display_name":"gluten","score":0.4440000057220459},{"id":"https://openalex.org/keywords/celiac-disease","display_name":"celiac disease","score":0.9629999995231628},{"id":"https://openalex.org/keywords/non-celiac-gluten-sensitivity","display_name":"non-celiac gluten sensitivity","score":0.9860000014305115},{"id":"https://openalex.org/keywords/positional-cloning","display_name":"positional cloning","score":0.6949999928474426},{"id":"https://openalex.org/keywords/wheat","display_name":"wheat","score":0.7239999771118164},{"id":"https://openalex.org/keywords/gliadin","display_name":"gliadin","score":0.7459999918937683},{"id":"https://openalex.org/keywords/low-molecular-weight-glutenin-subunits","display_name":"low molecular weight glutenin subunits","score":0.9890000224113464},{"id":"https://openalex.org/keywords/homeologs","display_name":"homeologs","score":0.6790000200271606},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.824999988079071},{"id":"https://openalex.org/keywords/transgenic-complementation","display_name":"transgenic complementation","score":0.7039999961853027},{"id":"https://openalex.org/keywords/seed-storage-proteins","display_name":"seed storage proteins","score":0.6679999828338623}],"concepts":[{"id":"https://openalex.org/C2779687958","wikidata":"https://www.wikidata.org/wiki/Q425051","display_name":"Glutenin","level":4,"score":0.9106458425521851},{"id":"https://openalex.org/C2778987702","wikidata":"https://www.wikidata.org/wiki/Q7215110","display_name":"Secale","level":2,"score":0.8472386598587036},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8275193572044373},{"id":"https://openalex.org/C2780092158","wikidata":"https://www.wikidata.org/wiki/Q279074","display_name":"Gliadin","level":3,"score":0.6813862919807434},{"id":"https://openalex.org/C2776336767","wikidata":"https://www.wikidata.org/wiki/Q188251","display_name":"Gluten","level":2,"score":0.6400274038314819},{"id":"https://openalex.org/C2993665447","wikidata":"https://www.wikidata.org/wiki/Q11577","display_name":"Hordeum vulgare","level":3,"score":0.6283223628997803},{"id":"https://openalex.org/C97564808","wikidata":"https://www.wikidata.org/wiki/Q425526","display_name":"Storage protein","level":3,"score":0.5790635943412781},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.5697254538536072},{"id":"https://openalex.org/C2780165273","wikidata":"https://www.wikidata.org/wiki/Q424471","display_name":"Prolamin","level":4,"score":0.5496887564659119},{"id":"https://openalex.org/C2777749068","wikidata":"https://www.wikidata.org/wiki/Q157770","display_name":"Brachypodium","level":4,"score":0.5371642112731934},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.4827350974082947},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.46962833404541016},{"id":"https://openalex.org/C143191323","wikidata":"https://www.wikidata.org/wiki/Q118406","display_name":"Ploidy","level":3,"score":0.4428040385246277},{"id":"https://openalex.org/C2780068994","wikidata":"https://www.wikidata.org/wiki/Q161098","display_name":"Common wheat","level":4,"score":0.43939024209976196},{"id":"https://openalex.org/C2777911459","wikidata":"https://www.wikidata.org/wiki/Q2352209","display_name":"Brachypodium distachyon","level":4,"score":0.41379520297050476},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4019731879234314},{"id":"https://openalex.org/C46757340","wikidata":"https://www.wikidata.org/wiki/Q43238","display_name":"Poaceae","level":2,"score":0.3230617642402649},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.2395961582660675},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2092795968055725},{"id":"https://openalex.org/C30481170","wikidata":"https://www.wikidata.org/wiki/Q37748","display_name":"Chromosome","level":3,"score":0.16760587692260742},{"id":"https://openalex.org/C104292427","wikidata":"https://www.wikidata.org/wiki/Q899781","display_name":"Protein subunit","level":3,"score":0.16102340817451477}],"mesh":[{"descriptor_ui":"D001467","descriptor_name":"Hordeum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004171","descriptor_name":"Diploidy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004252","descriptor_name":"DNA Mutational Analysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005983","descriptor_name":"Glutens","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014908","descriptor_name":"Triticum","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D017423","descriptor_name":"Sequence Analysis, RNA","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020125","descriptor_name":"Mutation, Missense","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055315","descriptor_name":"Prolamins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1104/pp.18.00771","doi":"https://doi.org/10.1104/pp.18.00771","is_oa":true,"landing_page_url":"https://doi.org/10.1104/pp.18.00771","pdf_url":null,"source":{"id":"https://openalex.org/S42294715","display_name":"PLANT PHYSIOLOGY","issn_l":"0032-0889","issn":["0032-0889","1532-2548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Physiology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6446766","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6446766","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Physiol","raw_type":"Text"},{"id":"pmid:30696748","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30696748","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant physiology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1104/pp.18.00771","doi":"https://doi.org/10.1104/pp.18.00771","is_oa":true,"landing_page_url":"https://doi.org/10.1104/pp.18.00771","pdf_url":null,"source":{"id":"https://openalex.org/S42294715","display_name":"PLANT PHYSIOLOGY","issn_l":"0032-0889","issn":["0032-0889","1532-2548"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-3","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311648","host_organization_name":"Oxford University Press","host_organization_lineage":["https://openalex.org/P4310311648","https://openalex.org/P4310311647"],"host_organization_lineage_names":["Oxford University Press","University of Oxford"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Plant Physiology","raw_type":"journal-article"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/2","score":0.9208999872207642,"display_name":"Zero hunger"},{"id":"https://metadata.un.org/sdg/3","score":0.5683000087738037,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G246248527","display_name":null,"funder_award_id":"R42 DK072721","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G2690991350","display_name":"TILLING wheat for reduced celiac disease causing proteins","funder_award_id":"5r42dk072721-03","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"},{"id":"https://openalex.org/G6357300181","display_name":"Reduced gluten cereal grains","funder_award_id":"R42DK097976","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":81,"referenced_works":["https://openalex.org/W988029549","https://openalex.org/W1497535479","https://openalex.org/W1507633773","https://openalex.org/W1516768294","https://openalex.org/W1531267945","https://openalex.org/W1544004437","https://openalex.org/W1967174206","https://openalex.org/W1972919397","https://openalex.org/W1976242922","https://openalex.org/W1978542424","https://openalex.org/W1982989214","https://openalex.org/W1986158569","https://openalex.org/W1989368184","https://openalex.org/W1998647648","https://openalex.org/W2004033858","https://openalex.org/W2007019025","https://openalex.org/W2009070283","https://openalex.org/W2012974956","https://openalex.org/W2015556811","https://openalex.org/W2016525208","https://openalex.org/W2021340226","https://openalex.org/W2023285100","https://openalex.org/W2023417060","https://openalex.org/W2024405748","https://openalex.org/W2031568164","https://openalex.org/W2034153125","https://openalex.org/W2034767282","https://openalex.org/W2035949543","https://openalex.org/W2037098737","https://openalex.org/W2042213519","https://openalex.org/W2043236266","https://openalex.org/W2044551150","https://openalex.org/W2045439285","https://openalex.org/W2050842004","https://openalex.org/W2056889999","https://openalex.org/W2070237426","https://openalex.org/W2070761024","https://openalex.org/W2072715465","https://openalex.org/W2073588294","https://openalex.org/W2076865097","https://openalex.org/W2077284873","https://openalex.org/W2082261438","https://openalex.org/W2083562009","https://openalex.org/W2085842874","https://openalex.org/W2088997507","https://openalex.org/W2091375086","https://openalex.org/W2093922969","https://openalex.org/W2098983472","https://openalex.org/W2101962523","https://openalex.org/W2102681666","https://openalex.org/W2103052000","https://openalex.org/W2111006781","https://openalex.org/W2112078820","https://openalex.org/W2118019845","https://openalex.org/W2118140755","https://openalex.org/W2118722022","https://openalex.org/W2127806007","https://openalex.org/W2140343272","https://openalex.org/W2143238378","https://openalex.org/W2147039301","https://openalex.org/W2147587252","https://openalex.org/W2147980878","https://openalex.org/W2153269523","https://openalex.org/W2162973505","https://openalex.org/W2164159324","https://openalex.org/W2165859953","https://openalex.org/W2166408626","https://openalex.org/W2167663411","https://openalex.org/W2170267194","https://openalex.org/W2179575365","https://openalex.org/W2263251097","https://openalex.org/W2290882432","https://openalex.org/W2466173038","https://openalex.org/W2571196999","https://openalex.org/W2741991215","https://openalex.org/W2756004972","https://openalex.org/W2780026058","https://openalex.org/W2802451498","https://openalex.org/W3134084687","https://openalex.org/W4237938708","https://openalex.org/W4251897673"],"related_works":["https://openalex.org/W2809536300","https://openalex.org/W4214932428","https://openalex.org/W7220792962","https://openalex.org/W2756004972","https://openalex.org/W1994064646","https://openalex.org/W7222788449","https://openalex.org/W4392236782","https://openalex.org/W3030074889","https://openalex.org/W3047699218","https://openalex.org/W2470683310"],"abstract_inverted_index":{"Celiac":[0],"disease":[1,55],"is":[2,18,64],"the":[3,80,97,111,116,124,142,146,154],"most":[4,81],"common":[5],"food-induced":[6],"enteropathy":[7],"in":[8,34,42,76,106,134,141,153,161],"humans,":[9],"with":[10,119],"a":[11,57,101,120,162],"prevalence":[12],"of":[13,52,73,79,123,145,157],"approximately":[14],"1%":[15],"worldwide.":[16],"It":[17],"induced":[19,138],"by":[20,114,172,182],"digestion-resistant,":[21],"proline-":[22],"and":[23,46,56,92,128,168,176,179],"glutamine-rich":[24],"seed":[25],"storage":[26],"proteins,":[27],"collectively":[28],"referred":[29],"to":[30,70,95,136,174],"as":[31],"gluten,":[32],"found":[33],"wheat":[35,148,160,164],"(Triticum":[36],"aestivum).":[37],"Related":[38],"prolamins":[39],"are":[40],"present":[41],"barley":[43,126],"(Hordeum":[44],"vulgare)":[45],"rye":[47],"(Secale":[48],"cereale).":[49],"The":[50],"incidence":[51],"both":[53],"celiac":[54],"related":[58],"condition":[59],"called":[60],"nonceliac":[61],"gluten":[62,75],"sensitivity":[63],"increasing.":[65],"This":[66],"has":[67],"prompted":[68],"efforts":[69],"identify":[71,96,137],"methods":[72],"lowering":[74],"wheat,":[77],"one":[78],"important":[82],"cereal":[83],"crops.":[84],"Here,":[85],"we":[86],"used":[87,130],"bulked":[88],"segregant":[89],"RNA":[90],"sequencing":[91],"map-based":[93],"cloning":[94],"genetic":[98],"lesion":[99],"underlying":[100],"recessive,":[102],"low-prolamin":[103],"mutation":[104],"(lys3a)":[105],"diploid":[107],"barley.":[108],"We":[109],"confirmed":[110],"mutant":[112,118],"identity":[113],"complementing":[115],"lys3a":[117],"transgenic":[121],"copy":[122],"wild-type":[125],"gene":[127],"then":[129],"targeting-induced":[131],"local":[132],"lesions":[133],"genomes":[135],"single-nucleotide":[139],"polymorphisms":[140],"three":[143,155],"homeologs":[144],"corresponding":[147],"gene.":[149],"Combining":[150],"inactivating":[151],"mutations":[152],"subgenomes":[156],"hexaploid":[158],"bread":[159],"single":[163],"line":[165],"lowered":[166],"gliadin":[167],"low-molecular-weight":[169],"glutenin":[170],"accumulation":[171],"50%":[173],"60%":[175],"increased":[177],"free":[178],"protein-bound":[180],"lysine":[181],"33%.":[183]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":6},{"year":2023,"cited_by_count":6},{"year":2022,"cited_by_count":7},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":2}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2019-02-21T00:00:00"}