{"id":"https://openalex.org/W2913793261","doi":"https://doi.org/10.3390/ph12010030","title":"Iron in Lung Pathology","display_name":"Iron in Lung Pathology","publication_year":2019,"publication_date":"2019-02-15","ids":{"openalex":"https://openalex.org/W2913793261","doi":"https://doi.org/10.3390/ph12010030","mag":"2913793261","pmid":"https://pubmed.ncbi.nlm.nih.gov/30781366","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6469192"},"language":"en","primary_location":{"id":"doi:10.3390/ph12010030","doi":"https://doi.org/10.3390/ph12010030","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ph12010030","pdf_url":"https://www.mdpi.com/1424-8247/12/1/30/pdf?version=1550221829","source":{"id":"https://openalex.org/S16322639","display_name":"Pharmaceuticals","issn_l":"1424-8247","issn":["1424-8247"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals","raw_type":"journal-article"},"volume":null,"type":"review","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/1424-8247/12/1/30/pdf?version=1550221829","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000061417","display_name":"Vida Zhang","orcid":"https://orcid.org/0000-0003-1956-2671","observed_orcids":["https://orcid.org/0000-0003-1956-2671"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Vida Zhang","raw_affiliation_strings":["Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Medical Pharmacology, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036220506","display_name":"Elizabeta Nemeth","orcid":"https://orcid.org/0000-0002-3477-2397","observed_orcids":["https://orcid.org/0000-0002-3477-2397"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elizabeta Nemeth","raw_affiliation_strings":["Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5043324626","display_name":"Airie Kim","orcid":"https://orcid.org/0000-0002-8454-4472","observed_orcids":["https://orcid.org/0000-0002-8454-4472"]},"institutions":[{"id":"https://openalex.org/I161318765","display_name":"University of California, Los Angeles","ror":"https://ror.org/046rm7j60","country_code":"US","type":"education","lineage":["https://openalex.org/I161318765"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Airie Kim","raw_affiliation_strings":["Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, David Geffen School of Medicine at the University of California, Los Angeles, CA 90095, USA","institution_ids":["https://openalex.org/I161318765"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5043324626"],"corresponding_institution_ids":["https://openalex.org/I161318765"],"apc_list":{"value":1000,"currency":"CHF","value_usd":1013},"apc_paid":{"value":1000,"currency":"CHF","value_usd":1013},"fwci":1.3487,"has_fulltext":true,"cited_by_count":56,"citation_normalized_percentile":{"value":0.77696859,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"12","issue":"1","first_page":"30","last_page":"30"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10452","display_name":"Iron Metabolism and Disorders","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11297","display_name":"Ferroptosis and cancer prognosis","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/iron-homeostasis","display_name":"iron homeostasis","score":0.8270000219345093},{"id":"https://openalex.org/keywords/iron-metabolism","display_name":"iron metabolism","score":0.47099998593330383},{"id":"https://openalex.org/keywords/pulmonary-infection","display_name":"pulmonary infection","score":0.7149999737739563},{"id":"https://openalex.org/keywords/airway-disease","display_name":"airway disease","score":0.9490000009536743},{"id":"https://openalex.org/keywords/lung-injury","display_name":"lung injury","score":0.9869999885559082}],"concepts":[{"id":"https://openalex.org/C2911035656","wikidata":"https://www.wikidata.org/wiki/Q5925744","display_name":"Iron homeostasis","level":3,"score":0.7886512279510498},{"id":"https://openalex.org/C2777714996","wikidata":"https://www.wikidata.org/wiki/Q7886","display_name":"Lung","level":2,"score":0.741544246673584},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6166319847106934},{"id":"https://openalex.org/C105922876","wikidata":"https://www.wikidata.org/wiki/Q1423981","display_name":"Airway","level":2,"score":0.549325704574585},{"id":"https://openalex.org/C63645605","wikidata":"https://www.wikidata.org/wiki/Q103191","display_name":"Homeostasis","level":2,"score":0.5302935242652893},{"id":"https://openalex.org/C2983914783","wikidata":"https://www.wikidata.org/wiki/Q3286546","display_name":"Lung disease","level":3,"score":0.4631829261779785},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.453507661819458},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.39262357354164124},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.34526264667510986},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.3235047161579132},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26394593715667725},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13971391320228577},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.09581685066223145},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.0}],"mesh":[],"locations_count":6,"locations":[{"id":"doi:10.3390/ph12010030","doi":"https://doi.org/10.3390/ph12010030","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ph12010030","pdf_url":"https://www.mdpi.com/1424-8247/12/1/30/pdf?version=1550221829","source":{"id":"https://openalex.org/S16322639","display_name":"Pharmaceuticals","issn_l":"1424-8247","issn":["1424-8247"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6469192","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6469192","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals (Basel)","raw_type":"Text"},{"id":"pmid:30781366","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30781366","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals (Basel, Switzerland)","raw_type":"Journal Article"},{"id":"pmh:oai:escholarship.org:ark:/13030/qt3n92j1p5","doi":null,"is_oa":true,"landing_page_url":"https://escholarship.org/uc/item/3n92j1p5","pdf_url":"https://escholarship.org/uc/item/3n92j1p5","source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceuticals, vol 12, iss 1","raw_type":"article"},{"id":"pmh:oai:doaj.org/article:81b2d01cb16f4e309f213dbf0eecb267","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/81b2d01cb16f4e309f213dbf0eecb267","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceuticals, Vol 12, Iss 1, p 30 (2019)","raw_type":"article"},{"id":"pmh:oai:escholarship.org/ark:/13030/qt3n92j1p5","doi":null,"is_oa":false,"landing_page_url":"https://escholarship.org/uc/item/3n92j1p5","pdf_url":null,"source":{"id":"https://openalex.org/S4306400115","display_name":"eScholarship (California Digital Library)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801248553","host_organization_name":"California Digital Library","host_organization_lineage":["https://openalex.org/I2801248553"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pharmaceuticals (Basel, Switzerland), vol 12, iss 1","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/ph12010030","doi":"https://doi.org/10.3390/ph12010030","is_oa":true,"landing_page_url":"https://doi.org/10.3390/ph12010030","pdf_url":"https://www.mdpi.com/1424-8247/12/1/30/pdf?version=1550221829","source":{"id":"https://openalex.org/S16322639","display_name":"Pharmaceuticals","issn_l":"1424-8247","issn":["1424-8247"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pharmaceuticals","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G4646822326","display_name":"Ferroportin Structure and function","funder_award_id":"R01DK107309","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G5874718806","display_name":"Acute Anemia of Inflammation: Mechanisms and Novel Therapies","funder_award_id":"K08HL127293","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2913793261.pdf","grobid_xml":"https://content.openalex.org/works/W2913793261.grobid-xml"},"referenced_works_count":78,"referenced_works":["https://openalex.org/W1677338","https://openalex.org/W1141274631","https://openalex.org/W1570067866","https://openalex.org/W1849233731","https://openalex.org/W1952983243","https://openalex.org/W1970460202","https://openalex.org/W1972747642","https://openalex.org/W1974844038","https://openalex.org/W1978162577","https://openalex.org/W1979372328","https://openalex.org/W1980042430","https://openalex.org/W1980401357","https://openalex.org/W1980551377","https://openalex.org/W1980889801","https://openalex.org/W1981207221","https://openalex.org/W1989031118","https://openalex.org/W1994327706","https://openalex.org/W1995729033","https://openalex.org/W1998351143","https://openalex.org/W1999053283","https://openalex.org/W2008906556","https://openalex.org/W2011312705","https://openalex.org/W2011538447","https://openalex.org/W2014262351","https://openalex.org/W2015203112","https://openalex.org/W2025063713","https://openalex.org/W2031283301","https://openalex.org/W2032656951","https://openalex.org/W2038979515","https://openalex.org/W2039198845","https://openalex.org/W2045637728","https://openalex.org/W2049912996","https://openalex.org/W2053850651","https://openalex.org/W2064775719","https://openalex.org/W2073018837","https://openalex.org/W2082056887","https://openalex.org/W2083022144","https://openalex.org/W2084577971","https://openalex.org/W2097766703","https://openalex.org/W2098198071","https://openalex.org/W2100511558","https://openalex.org/W2102581269","https://openalex.org/W2106309610","https://openalex.org/W2111797468","https://openalex.org/W2120579640","https://openalex.org/W2126286427","https://openalex.org/W2127751018","https://openalex.org/W2131265733","https://openalex.org/W2132155262","https://openalex.org/W2132471916","https://openalex.org/W2134096693","https://openalex.org/W2135665959","https://openalex.org/W2137800298","https://openalex.org/W2140534638","https://openalex.org/W2142374658","https://openalex.org/W2143578711","https://openalex.org/W2143671605","https://openalex.org/W2144126297","https://openalex.org/W2146444665","https://openalex.org/W2150926825","https://openalex.org/W2151081293","https://openalex.org/W2164717439","https://openalex.org/W2168157030","https://openalex.org/W2170671441","https://openalex.org/W2255333206","https://openalex.org/W2327258697","https://openalex.org/W2329815032","https://openalex.org/W2425386444","https://openalex.org/W2567903706","https://openalex.org/W2580415908","https://openalex.org/W2603067923","https://openalex.org/W2605628036","https://openalex.org/W2609745626","https://openalex.org/W2611092877","https://openalex.org/W2767090060","https://openalex.org/W2801429697","https://openalex.org/W2885688680","https://openalex.org/W4229679803"],"related_works":["https://openalex.org/W2908195236","https://openalex.org/W2610500049","https://openalex.org/W2329815032","https://openalex.org/W7160492114","https://openalex.org/W2074069122","https://openalex.org/W7005698805","https://openalex.org/W7033808546","https://openalex.org/W2187694590","https://openalex.org/W3033104425","https://openalex.org/W1992657781"],"abstract_inverted_index":{"The":[0,9],"lung":[1,49,63,68],"presents":[2],"a":[3],"unique":[4],"challenge":[5],"for":[6,76],"iron":[7,21,35,50,58],"homeostasis.":[8],"entire":[10],"airway":[11,65],"is":[12],"in":[13,59],"direct":[14],"contact":[15],"with":[16],"the":[17,28,55,60,77],"environment":[18],"and":[19,24,30,47,67],"its":[20],"particulate":[22],"matter":[23],"iron-utilizing":[25],"microbes.":[26],"However,":[27],"homeostatic":[29],"adaptive":[31],"mechanisms":[32,71],"of":[33,45,57,62,80],"pulmonary":[34],"regulation":[36],"are":[37],"poorly":[38],"understood.":[39],"This":[40],"review":[41],"provides":[42],"an":[43,73],"overview":[44],"systemic":[46],"local":[48],"regulation,":[51],"as":[52,54],"well":[53],"roles":[56],"development":[61,79],"infections,":[64],"disease,":[66],"injury.":[69],"These":[70],"provide":[72],"important":[74],"foundation":[75],"ongoing":[78],"therapeutic":[81],"applications.":[82]},"counts_by_year":[{"year":2026,"cited_by_count":5},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":12},{"year":2022,"cited_by_count":16},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":6},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2019-02-21T00:00:00"}