{"id":"https://openalex.org/W2913789604","doi":"https://doi.org/10.1177/2054358119828388","title":"Central Blood Pressure and Pulse Wave Velocity Changes Post Renal Denervation in Patients With Stages 3 and 4 Chronic Kidney Disease: The Regina RDN Study","display_name":"Central Blood Pressure and Pulse Wave Velocity Changes Post Renal Denervation in Patients With Stages 3 and 4 Chronic Kidney Disease: The Regina RDN Study","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2913789604","doi":"https://doi.org/10.1177/2054358119828388","mag":"2913789604","pmid":"https://pubmed.ncbi.nlm.nih.gov/30792873","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6376516"},"language":"en","primary_location":{"id":"doi:10.1177/2054358119828388","doi":"https://doi.org/10.1177/2054358119828388","is_oa":true,"landing_page_url":"https://doi.org/10.1177/2054358119828388","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/2054358119828388","source":{"id":"https://openalex.org/S2764509245","display_name":"Canadian Journal of Kidney Health and Disease","issn_l":"2054-3581","issn":["2054-3581"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Kidney Health and Disease","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://journals.sagepub.com/doi/pdf/10.1177/2054358119828388","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5019641735","display_name":"Bhanu Prasad","orcid":"https://orcid.org/0000-0002-1139-4821","observed_orcids":["https://orcid.org/0000-0002-1139-4821"]},"institutions":[{"id":"https://openalex.org/I4210118251","display_name":"Regina General Hospital","ror":"https://ror.org/029tn5b56","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210118251"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Bhanu Prasad","raw_affiliation_strings":["Section of Nephrology, Department of Medicine, Regina General Hospital, SK, Canada"],"raw_orcid":"https://orcid.org/0000-0002-1139-4821","affiliations":[{"raw_affiliation_string":"Section of Nephrology, Department of Medicine, Regina General Hospital, SK, Canada","institution_ids":["https://openalex.org/I4210118251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112415111","display_name":"Warren E. Berry","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Warren Berry","raw_affiliation_strings":["Research and Performance Support, Wascana Hospital, Regina, SK, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Research and Performance Support, Wascana Hospital, Regina, SK, Canada","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5009685311","display_name":"Kunal Goyal","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210118251","display_name":"Regina General Hospital","ror":"https://ror.org/029tn5b56","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210118251"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Kunal Goyal","raw_affiliation_strings":["Department of Radiology, Regina General Hospital, SK, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Regina General Hospital, SK, Canada","institution_ids":["https://openalex.org/I4210118251"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057244934","display_name":"Payam Dehghani","orcid":"https://orcid.org/0000-0001-7858-7989","observed_orcids":["https://orcid.org/0000-0001-7858-7989"]},"institutions":[{"id":"https://openalex.org/I4210118251","display_name":"Regina General Hospital","ror":"https://ror.org/029tn5b56","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I4210118251"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Payam Dehghani","raw_affiliation_strings":["Section of Cardiology, Department of Medicine, Regina General Hospital, SK, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Section of Cardiology, Department of Medicine, Regina General Hospital, SK, Canada","institution_ids":["https://openalex.org/I4210118251"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5047317486","display_name":"Raymond R. Townsend","orcid":"https://orcid.org/0000-0002-3215-9118","observed_orcids":["https://orcid.org/0000-0002-3215-9118"]},"institutions":[{"id":"https://openalex.org/I79576946","display_name":"University of Pennsylvania","ror":"https://ror.org/00b30xv10","country_code":"US","type":"education","lineage":["https://openalex.org/I79576946"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Raymond R. Townsend","raw_affiliation_strings":["Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA","institution_ids":["https://openalex.org/I79576946"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5019641735"],"corresponding_institution_ids":["https://openalex.org/I4210118251"],"apc_list":{"value":1800,"currency":"USD","value_usd":1800},"apc_paid":{"value":1800,"currency":"USD","value_usd":1800},"fwci":1.2594,"has_fulltext":false,"cited_by_count":19,"citation_normalized_percentile":{"value":0.81040027,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"6","issue":null,"first_page":"2054358119828388","last_page":"2054358119828388"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.6845999956130981,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.6845999956130981,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10924","display_name":"Cardiovascular Health and Disease Prevention","score":0.3003000020980835,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12067","display_name":"Renal and Vascular Pathologies","score":0.0066999997943639755,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/renal-denervation","display_name":"renal denervation","score":0.996999979019165},{"id":"https://openalex.org/keywords/central-blood-pressure","display_name":"central blood pressure","score":0.8180000185966492},{"id":"https://openalex.org/keywords/pulse-wave-velocity","display_name":"pulse wave velocity","score":0.9829999804496765},{"id":"https://openalex.org/keywords/arterial-stiffness","display_name":"arterial stiffness","score":0.9769999980926514},{"id":"https://openalex.org/keywords/chronic-kidney-disease","display_name":"chronic kidney disease","score":0.8980000019073486},{"id":"https://openalex.org/keywords/resistant-hypertension","display_name":"resistant hypertension","score":0.9649999737739563},{"id":"https://openalex.org/keywords/ambulatory-blood-pressure","display_name":"ambulatory blood pressure","score":0.8510000109672546},{"id":"https://openalex.org/keywords/brachial-blood-pressure","display_name":"brachial blood pressure","score":0.8889999985694885},{"id":"https://openalex.org/keywords/glomerular-filtration-rate","display_name":"glomerular filtration rate","score":0.9380000233650208},{"id":"https://openalex.org/keywords/proteinuria","display_name":"proteinuria","score":0.7519999742507935},{"id":"https://openalex.org/keywords/echocardiographic-parameters","display_name":"echocardiographic parameters","score":0.6039999723434448},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.4169999957084656},{"id":"https://openalex.org/keywords/antihypertensive-medication-reduction","display_name":"antihypertensive medication reduction","score":0.718999981880188},{"id":"https://openalex.org/keywords/renal-function-decline","display_name":"renal function decline","score":0.3400000035762787},{"id":"https://openalex.org/keywords/left-ventricular-hypertrophy","display_name":"left ventricular hypertrophy","score":0.5889999866485596}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.932018518447876},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.7573976516723633},{"id":"https://openalex.org/C2775850156","wikidata":"https://www.wikidata.org/wiki/Q4797538","display_name":"Arterial stiffness","level":3,"score":0.7043672800064087},{"id":"https://openalex.org/C149323552","wikidata":"https://www.wikidata.org/wiki/Q3090739","display_name":"Ambulatory blood pressure","level":3,"score":0.6523371934890747},{"id":"https://openalex.org/C2778319312","wikidata":"https://www.wikidata.org/wiki/Q2118022","display_name":"Pulse wave velocity","level":3,"score":0.6521592140197754},{"id":"https://openalex.org/C2778653478","wikidata":"https://www.wikidata.org/wiki/Q1054718","display_name":"Kidney disease","level":2,"score":0.6370839476585388},{"id":"https://openalex.org/C159641895","wikidata":"https://www.wikidata.org/wiki/Q108377937","display_name":"Renal function","level":2,"score":0.625820517539978},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4898824095726013},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.47227558493614197},{"id":"https://openalex.org/C35785553","wikidata":"https://www.wikidata.org/wiki/Q756720","display_name":"Ambulatory","level":2,"score":0.4722549021244049},{"id":"https://openalex.org/C17140001","wikidata":"https://www.wikidata.org/wiki/Q1759415","display_name":"Pulse pressure","level":3,"score":0.4683710038661957}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.1177/2054358119828388","doi":"https://doi.org/10.1177/2054358119828388","is_oa":true,"landing_page_url":"https://doi.org/10.1177/2054358119828388","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/2054358119828388","source":{"id":"https://openalex.org/S2764509245","display_name":"Canadian Journal of Kidney Health and Disease","issn_l":"2054-3581","issn":["2054-3581"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Kidney Health and Disease","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5380025","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6376516","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6376516","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6376516","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Can J Kidney Health Dis","raw_type":"Text"},{"id":"pmid:30792873","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30792873","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian journal of kidney health and disease","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:674a13732e4a4a459895249d0be2e2df","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/674a13732e4a4a459895249d0be2e2df","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Canadian Journal of Kidney Health and Disease, Vol 6 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1177/2054358119828388","doi":"https://doi.org/10.1177/2054358119828388","is_oa":true,"landing_page_url":"https://doi.org/10.1177/2054358119828388","pdf_url":"https://journals.sagepub.com/doi/pdf/10.1177/2054358119828388","source":{"id":"https://openalex.org/S2764509245","display_name":"Canadian Journal of Kidney Health and Disease","issn_l":"2054-3581","issn":["2054-3581"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","ki-jl-1","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320017","host_organization_name":"SAGE Publishing","host_organization_lineage":["https://openalex.org/P4310320017"],"host_organization_lineage_names":["SAGE Publishing"],"type":"journal"},"license":"cc-by-nc","license_id":"https://openalex.org/licenses/cc-by-nc","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Canadian Journal of Kidney Health and Disease","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/clinical-trial","display_name":"Clinical Trial"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2913789604.pdf"},"referenced_works_count":23,"referenced_works":["https://openalex.org/W242434088","https://openalex.org/W1583834060","https://openalex.org/W1971927567","https://openalex.org/W1995381509","https://openalex.org/W2017767820","https://openalex.org/W2021334280","https://openalex.org/W2049739776","https://openalex.org/W2076383107","https://openalex.org/W2088323626","https://openalex.org/W2096998744","https://openalex.org/W2099144698","https://openalex.org/W2099897414","https://openalex.org/W2115409589","https://openalex.org/W2115461708","https://openalex.org/W2125914602","https://openalex.org/W2131490804","https://openalex.org/W2141731247","https://openalex.org/W2147047643","https://openalex.org/W2160489770","https://openalex.org/W2161246417","https://openalex.org/W2212524554","https://openalex.org/W3016405830","https://openalex.org/W4234841815"],"related_works":["https://openalex.org/W2736995898","https://openalex.org/W2588647902","https://openalex.org/W7163054651","https://openalex.org/W4388793149","https://openalex.org/W4386420935","https://openalex.org/W2518901648","https://openalex.org/W4315710043","https://openalex.org/W4415476298","https://openalex.org/W2603898925","https://openalex.org/W2792944286"],"abstract_inverted_index":{"Background:":[0],"Central":[1],"aortic":[2],"blood":[3,16,51,58,132,135,150,179,256,280,397,432],"pressures":[4,52,136,257,281,398],"and":[5,30,56,69,107,144,147,153,190,194,200,212,225,269,293,312,317,343,369,416,422],"arterial":[6,60],"stiffness":[7],"are":[8],"better":[9],"indicators":[10],"of":[11,47,116,119,149,202,222,249,445],"cardiovascular":[12],"outcomes":[13,215],"than":[14],"brachial":[15,54],"pressures.":[17],"However,":[18],"their":[19],"response":[20],"to":[21,167,239,401,405],"renal":[22],"denervation":[23],"(RDN)":[24],"in":[25,163,176,197,395,413,430],"patients":[26,99],"with":[27,79,100,110,381,425],"Stage":[28,31,101,104],"3":[29,102],"4":[32,105],"chronic":[33],"kidney":[34,187],"disease":[35],"(CKD)":[36],"has":[37],"not":[38],"yet":[39],"been":[40],"examined.":[41],"Objective:":[42],"To":[43],"evaluate":[44],"the":[45,87,161,195,198,205,213,442],"impact":[46],"RDN":[48,233],"on":[49,74,137],"central":[50,255,414],"(CBP),":[53],"(office":[55],"ambulatory)":[57],"pressures,":[59,183,415],"stiffness,":[61],"glomerular":[62,354],"filtration":[63,355],"rate":[64,356],"(GFR),":[65],"24-hour":[66,131,141,181,191,304,431],"urine":[67,142],"protein,":[68],"selective":[70],"cardiac":[71],"parameters":[72],"observed":[73],"echocardiograms.":[75],"Design:":[76],"Single-center,":[77],"single-arm":[78],"pre-/post-RDN":[80],"follow-up.":[81],"Setting:":[82],"Patients":[83],"were":[84,125,216,260,284],"recruited":[85],"from":[86,165,231,399],"multidisciplinary":[88],"CKD":[89,106],"clinic,":[90],"Regina":[91],"General":[92],"Hospital,":[93],"Canada.":[94],"Patients:":[95],"About":[96],"25":[97],"consecutive":[98],"or":[103,113,438],"resistant":[108],"hypertension,":[109],"no":[111,382,426],"radiological":[112],"laboratory":[114],"evidence":[115],"secondary":[117,214],"causes":[118],"hypertension.":[120],"Measurements:":[121],"The":[122,156,209],"key":[123],"measurements":[124],"CBP,":[126,177],"pulse":[127,184,327,417],"wave":[128,185,328,418],"velocity,":[129,186],"ambulatory":[130,182,303],"pressure,":[133,180],"office":[134,178,279,396],"BP":[138],"Tru,":[139],"GFR,":[140],"protein":[143,192],"sodium,":[145],"dose":[146,201],"number":[148,199],"pressure":[151],"medication":[152],"doses.":[154],"Methods:":[155],"primary":[157,210],"outcome":[158,172,211],"measure":[159],"was":[160,237,251,308,333,362,367,391,409],"change":[162,196],"CBP":[164],"baseline":[166,263,287,311,332,336,361,400,440],"6":[168,267,291,315,341,365,402,421],"months":[169,268,273,292,297,316,321,342,366,373,444],"post-RDN.":[170],"Secondary":[171],"measures":[173],"included":[174],"changes":[175,230,428],"function":[188,435],"(eGFR":[189],"excretion),":[193],"medications":[203],"during":[204],"2-year":[206],"follow-up":[207],"period.":[208],"evaluated":[217],"using":[218],"a":[219,392,410],"Friedman\u2019s":[220],"analysis":[221],"variance":[223],"(ANOVA)":[224],"Wilcoxon":[226],"signed-rank":[227],"test":[228],"for":[229,243],"post":[232],"procedure.":[234],"Bonferroni":[235],"correction":[236],"used":[238],"adjust":[240],"P":[241,275,299,323,350,375],"values":[242],"multiple":[244],"testing.":[245],"A":[246],"two-sided":[247],"alpha":[248],".05":[250],"used.":[252],"Results:":[253],"Median":[254,278,302,326],"(mm":[258,282,306],"Hg)":[259,283,307],"127/75":[261],"at":[262,266,271,286,290,295,310,314,319,331,335,340,345,360,364,371,420,437],"versus":[264,288,337],"118/70":[265],"118/67":[270],"24":[272,296,320,372,406,423,443],"(":[274,298,322,349,374],"=":[276,324,351,376],".13).":[277],"148/76":[285],"135/75":[289],"133/75":[294],"\u2264":[300],".001).":[301],"day":[305],"148/64":[309],"146/68":[313],"152/67":[318],".60).":[325],"velocity":[329,419],"(m/s)":[330],"13.8":[334],"13.3":[338],"m/s":[339],"12.3":[344],"12":[346],"months\u2019":[347],"time":[348],".62).":[352],"Estimated":[353],"(mL/min/1.73m":[357],"2":[358],")":[359],"37,":[363],"36":[368],"34":[370],".33).":[377],"Limitations:":[378],"Single-center":[379],"study,":[380],"sham":[383],"arm.":[384],"Conclusions:":[385],"Our":[386],"study":[387],"demonstrates":[388],"that":[389],"there":[390],"significant":[393],"improvement":[394,412],"months,":[403,424],"maintained":[404],"months.":[407],"There":[408],"numerical":[411],"sustained":[427],"noted":[429],"pressure.":[433],"Kidney":[434],"remained":[436],"near":[439],"throughout":[441],"observation.":[446],"Trial":[447],"registration:":[448],"ClinicalTrials.gov":[449],"(NCT01832233).":[450]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":4},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":3}],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2019-02-21T00:00:00"}