{"id":"https://openalex.org/W2913321952","doi":null,"title":"Abstract 15369: Low Ldl-Cholesterol by Pcsk9 Variation and Mortality in 109,800 Individuals From the General Population","display_name":"Abstract 15369: Low Ldl-Cholesterol by Pcsk9 Variation and Mortality in 109,800 Individuals From the General Population","publication_year":2017,"publication_date":"2017-11-14","ids":{"openalex":"https://openalex.org/W2913321952","mag":"2913321952"},"language":"en","primary_location":{"id":"mag:2913321952","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/10.1161/circ.136.suppl_1.15369","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5007666581","display_name":"Marianne Benn","orcid":"https://orcid.org/0000-0002-1701-595X","observed_orcids":["https://orcid.org/0000-0002-1701-595X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marianne Benn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111623837","display_name":"Anne Tybj\u00e6rg\u2010Hansen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anne Tybj\u00e6rg\u2010Hansen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5079728437","display_name":"B\u00f8rge Gr\u00f8nne Nordestgaard","orcid":"https://orcid.org/0000-0002-1954-7220","observed_orcids":["https://orcid.org/0000-0002-1954-7220"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B\u00f8rge G. Nordestgaard","raw_affiliation_strings":[],"raw_orcid":"https://orcid.org/0000-0002-1954-7220","affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10394","display_name":"Lipoproteins and Cardiovascular Health","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12975","display_name":"Paraoxonase enzyme and polymorphisms","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/1308","display_name":"Clinical Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pcsk9","display_name":"PCSK9","score":0.9139999747276306},{"id":"https://openalex.org/keywords/ldl-cholesterol","display_name":"LDL cholesterol","score":0.671999990940094},{"id":"https://openalex.org/keywords/pcsk9-inhibition","display_name":"PCSK9 inhibition","score":0.7070000171661377},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.5239999890327454},{"id":"https://openalex.org/keywords/cardiovascular-risk","display_name":"cardiovascular risk","score":0.875},{"id":"https://openalex.org/keywords/genetic-variation","display_name":"genetic variation","score":0.6460000276565552},{"id":"https://openalex.org/keywords/low-ldl-cholesterol","display_name":"low LDL cholesterol","score":0.4569999873638153}],"concepts":[{"id":"https://openalex.org/C2780948078","wikidata":"https://www.wikidata.org/wiki/Q21130010","display_name":"PCSK9","level":5,"score":0.9537429213523865},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9088337421417236},{"id":"https://openalex.org/C3019550498","wikidata":"https://www.wikidata.org/wiki/Q28749","display_name":"Ldl cholesterol","level":3,"score":0.6152305006980896},{"id":"https://openalex.org/C2778334786","wikidata":"https://www.wikidata.org/wiki/Q1586270","display_name":"Variation (astronomy)","level":2,"score":0.5820122361183167},{"id":"https://openalex.org/C2778163477","wikidata":"https://www.wikidata.org/wiki/Q43656","display_name":"Cholesterol","level":2,"score":0.5208842754364014},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.49439120292663574},{"id":"https://openalex.org/C2778849439","wikidata":"https://www.wikidata.org/wiki/Q6397985","display_name":"Kexin","level":5,"score":0.47410470247268677},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3870745301246643},{"id":"https://openalex.org/C149923435","wikidata":"https://www.wikidata.org/wiki/Q37732","display_name":"Demography","level":1,"score":0.36117905378341675},{"id":"https://openalex.org/C43554185","wikidata":"https://www.wikidata.org/wiki/Q425649","display_name":"LDL receptor","level":4,"score":0.35267406702041626},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.21797394752502441},{"id":"https://openalex.org/C2780072125","wikidata":"https://www.wikidata.org/wiki/Q28350","display_name":"Lipoprotein","level":3,"score":0.13520631194114685},{"id":"https://openalex.org/C144024400","wikidata":"https://www.wikidata.org/wiki/Q21201","display_name":"Sociology","level":0,"score":0.0},{"id":"https://openalex.org/C44870925","wikidata":"https://www.wikidata.org/wiki/Q37547","display_name":"Astrophysics","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:2913321952","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/10.1161/circ.136.suppl_1.15369","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2888102916","https://openalex.org/W2950442821","https://openalex.org/W2067539811","https://openalex.org/W1963680304","https://openalex.org/W1748960794","https://openalex.org/W2954532436","https://openalex.org/W58023753","https://openalex.org/W2514205342","https://openalex.org/W2105896644","https://openalex.org/W2604950485"],"abstract_inverted_index":{"Introduction:":[0],"Low":[1],"levels":[2],"of":[3,9,22],"low-density-lipoprotein":[4],"(LDL)-cholesterol":[5],"due":[6],"to":[7],"inhibition":[8],"proprotein":[10],"convertase":[11],"subtilisin":[12],"kexin":[13],"9":[14],"(PCSK9)":[15],"may":[16],"be":[17],"associated":[18],"with":[19],"low":[20],"risk":[21],"cardiovascular":[23],"and":[24],"all...":[25]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2019-02-21T00:00:00"}