{"id":"https://openalex.org/W2913301887","doi":"https://doi.org/10.1016/j.euroneuro.2019.01.015","title":"P.1.12 Intellectual disability-related genes increase ADHD risk and locomotor activity in Drosophila melanogaster","display_name":"P.1.12 Intellectual disability-related genes increase ADHD risk and locomotor activity in Drosophila melanogaster","publication_year":2019,"publication_date":"2019-01-01","ids":{"openalex":"https://openalex.org/W2913301887","doi":"https://doi.org/10.1016/j.euroneuro.2019.01.015","mag":"2913301887"},"language":"en","primary_location":{"id":"doi:10.1016/j.euroneuro.2019.01.015","doi":"https://doi.org/10.1016/j.euroneuro.2019.01.015","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.euroneuro.2019.01.015","pdf_url":null,"source":{"id":"https://openalex.org/S168041952","display_name":"European Neuropsychopharmacology","issn_l":"0924-977X","issn":["0924-977X","1873-7862"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Neuropsychopharmacology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039784552","display_name":"Marieke Klein","orcid":"https://orcid.org/0000-0001-8784-5679","observed_orcids":["https://orcid.org/0000-0001-8784-5679"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["NL"],"is_corresponding":true,"raw_author_name":"M. Klein","raw_affiliation_strings":["Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4405261313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028439791","display_name":"Euginia L. Singgih","orcid":"https://orcid.org/0000-0003-0062-0755","observed_orcids":["https://orcid.org/0000-0003-0062-0755"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"E. Singgih","raw_affiliation_strings":["Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4405261313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071476409","display_name":"Anne van Rens","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A. Van Rens","raw_affiliation_strings":["Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4405261313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014114792","display_name":"Ditte Demontis","orcid":"https://orcid.org/0000-0001-9124-2766","observed_orcids":["https://orcid.org/0000-0001-9124-2766"]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"D. Demontis","raw_affiliation_strings":["Aarhus University, Department of Biomedicine, Aarhus, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aarhus University, Department of Biomedicine, Aarhus, Denmark","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035161779","display_name":"Anders Dupont B\u00f8rglum","orcid":"https://orcid.org/0000-0001-8627-7219","observed_orcids":["https://orcid.org/0000-0001-8627-7219"]},"institutions":[{"id":"https://openalex.org/I204337017","display_name":"Aarhus University","ror":"https://ror.org/01aj84f44","country_code":"DK","type":"education","lineage":["https://openalex.org/I204337017"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"A. B\u00f8rglum","raw_affiliation_strings":["Aarhus University, Department of Biomedicine, Aarhus, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Aarhus University, Department of Biomedicine, Aarhus, Denmark","institution_ids":["https://openalex.org/I204337017"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030485933","display_name":"Han G. Brunner","orcid":"https://orcid.org/0000-0001-9274-8865","observed_orcids":["https://orcid.org/0000-0001-9274-8865"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"H. Brunner","raw_affiliation_strings":["Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4405261313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029619884","display_name":"Alejandro Arias V\u00e1squez","orcid":"https://orcid.org/0000-0002-4786-0169","observed_orcids":["https://orcid.org/0000-0002-4786-0169"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A. Arias-Vasquez","raw_affiliation_strings":["Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics and Department of Psychiatry, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics and Department of Psychiatry, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4405261313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5025826954","display_name":"Annette Schenck","orcid":"https://orcid.org/0000-0002-6918-3314","observed_orcids":["https://orcid.org/0000-0002-6918-3314"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"A. Schenck","raw_affiliation_strings":["Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4405261313"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052091775","display_name":"Monique van der Voet","orcid":"https://orcid.org/0000-0002-8829-1767","observed_orcids":["https://orcid.org/0000-0002-8829-1767"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"M. Van der Voet","raw_affiliation_strings":["Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4405261313"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5038874292","display_name":"Barbara Franke","orcid":"https://orcid.org/0000-0003-4375-6572","observed_orcids":["https://orcid.org/0000-0003-4375-6572"]},"institutions":[{"id":"https://openalex.org/I145872427","display_name":"Radboud University Nijmegen","ror":"https://ror.org/016xsfp80","country_code":"NL","type":"education","lineage":["https://openalex.org/I145872427"]},{"id":"https://openalex.org/I2802934949","display_name":"Radboud University Medical Center","ror":"https://ror.org/05wg1m734","country_code":"NL","type":"funder","lineage":["https://openalex.org/I2802934949"]},{"id":"https://openalex.org/I4405261313","display_name":"Donders Institute for Brain, Cognition and Behaviour","ror":"https://ror.org/053sba816","country_code":"NL","type":"facility","lineage":["https://openalex.org/I145872427","https://openalex.org/I4405261313"]}],"countries":["NL"],"is_corresponding":false,"raw_author_name":"B. Franke","raw_affiliation_strings":["Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics and Department of Psychiatry, Nijmegen, The Netherlands"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Radboud university medical center- Donders Institute for Brain- Cognition and Behaviour, Department of Human Genetics and Department of Psychiatry, Nijmegen, The Netherlands","institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4405261313"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5039784552"],"corresponding_institution_ids":["https://openalex.org/I145872427","https://openalex.org/I2802934949","https://openalex.org/I4405261313"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.01310558,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"29","issue":null,"first_page":"S641","last_page":"S642"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.8300999999046326,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10537","display_name":"Attention Deficit Hyperactivity Disorder","score":0.8300999999046326,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11772","display_name":"Genetics and Neurodevelopmental Disorders","score":0.11760000139474869,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.01640000008046627,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/adhd-risk","display_name":"ADHD risk","score":0.9539999961853027},{"id":"https://openalex.org/keywords/locomotor-activity","display_name":"locomotor activity","score":0.9959999918937683},{"id":"https://openalex.org/keywords/drosophila-melanogaster","display_name":"Drosophila melanogaster","score":0.9409999847412109},{"id":"https://openalex.org/keywords/groove-machining","display_name":"groove machining","score":0.597000002861023},{"id":"https://openalex.org/keywords/machining-accuracy","display_name":"machining accuracy","score":0.6949999928474426}],"concepts":[{"id":"https://openalex.org/C523214423","wikidata":"https://www.wikidata.org/wiki/Q192047","display_name":"Machining","level":2,"score":0.6781635284423828},{"id":"https://openalex.org/C85617194","wikidata":"https://www.wikidata.org/wiki/Q2072794","display_name":"Particle swarm optimization","level":2,"score":0.6402161717414856},{"id":"https://openalex.org/C2779472054","wikidata":"https://www.wikidata.org/wiki/Q2377973","display_name":"Groove (engineering)","level":2,"score":0.6235371828079224},{"id":"https://openalex.org/C198082294","wikidata":"https://www.wikidata.org/wiki/Q3399648","display_name":"Position (finance)","level":2,"score":0.5300478935241699},{"id":"https://openalex.org/C173736775","wikidata":"https://www.wikidata.org/wiki/Q58964","display_name":"Drill","level":2,"score":0.49965667724609375},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4505782425403595},{"id":"https://openalex.org/C2778855872","wikidata":"https://www.wikidata.org/wiki/Q7286559","display_name":"Rake","level":2,"score":0.4256698191165924},{"id":"https://openalex.org/C2779218026","wikidata":"https://www.wikidata.org/wiki/Q1931980","display_name":"Grinding wheel","level":3,"score":0.4239163100719452},{"id":"https://openalex.org/C177148314","wikidata":"https://www.wikidata.org/wiki/Q170084","display_name":"Generalization","level":2,"score":0.4224488139152527},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.32886427640914917},{"id":"https://openalex.org/C78519656","wikidata":"https://www.wikidata.org/wiki/Q101333","display_name":"Mechanical engineering","level":1,"score":0.2895517945289612},{"id":"https://openalex.org/C11413529","wikidata":"https://www.wikidata.org/wiki/Q8366","display_name":"Algorithm","level":1,"score":0.2778318226337433},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.26353275775909424},{"id":"https://openalex.org/C2777571299","wikidata":"https://www.wikidata.org/wiki/Q3680646","display_name":"Grinding","level":2,"score":0.09869635105133057},{"id":"https://openalex.org/C134306372","wikidata":"https://www.wikidata.org/wiki/Q7754","display_name":"Mathematical analysis","level":1,"score":0.07188063859939575},{"id":"https://openalex.org/C10138342","wikidata":"https://www.wikidata.org/wiki/Q43015","display_name":"Finance","level":1,"score":0.0},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.euroneuro.2019.01.015","doi":"https://doi.org/10.1016/j.euroneuro.2019.01.015","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.euroneuro.2019.01.015","pdf_url":null,"source":{"id":"https://openalex.org/S168041952","display_name":"European Neuropsychopharmacology","issn_l":"0924-977X","issn":["0924-977X","1873-7862"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Neuropsychopharmacology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":5,"referenced_works":["https://openalex.org/W1581369687","https://openalex.org/W1973595527","https://openalex.org/W2051314902","https://openalex.org/W2559956310","https://openalex.org/W2802815532"],"related_works":["https://openalex.org/W2734322506","https://openalex.org/W4407732832","https://openalex.org/W7073015169","https://openalex.org/W3006062116","https://openalex.org/W2511308832","https://openalex.org/W3203766977","https://openalex.org/W2611165991","https://openalex.org/W2326882222","https://openalex.org/W2374677545","https://openalex.org/W6960510534"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2019-02-21T00:00:00"}