{"id":"https://openalex.org/W2913299062","doi":"https://doi.org/10.2174/1871530319666190206225635","title":"Diabetic Cognitive Dysfunction: From Bench to Clinic","display_name":"Diabetic Cognitive Dysfunction: From Bench to Clinic","publication_year":2020,"publication_date":"2020-06-04","ids":{"openalex":"https://openalex.org/W2913299062","doi":"https://doi.org/10.2174/1871530319666190206225635","mag":"2913299062","pmid":"https://pubmed.ncbi.nlm.nih.gov/30727866"},"language":"en","primary_location":{"id":"doi:10.2174/1871530319666190206225635","doi":"https://doi.org/10.2174/1871530319666190206225635","is_oa":false,"landing_page_url":"https://doi.org/10.2174/1871530319666190206225635","pdf_url":null,"source":{"id":"https://openalex.org/S33159018","display_name":"Current Medicinal Chemistry","issn_l":"0929-8673","issn":["0929-8673","1875-533X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Medicinal Chemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5047526193","display_name":"Jiyin Zhou","orcid":"https://orcid.org/0000-0003-4313-4191","observed_orcids":["https://orcid.org/0000-0003-4313-4191"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Jiyin Zhou","raw_affiliation_strings":["National Drug Clinical Trial Institution, the Second Affiliated Hospital, Army Medical University, Chongqing 400037, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Drug Clinical Trial Institution, the Second Affiliated Hospital, Army Medical University, Chongqing 400037, China","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088633074","display_name":"Zuo Zhang","orcid":"https://orcid.org/0000-0002-6752-3434","observed_orcids":["https://orcid.org/0000-0002-6752-3434"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zuo Zhang","raw_affiliation_strings":["National Drug Clinical Trial Institution, the Second Affiliated Hospital, Army Medical University, Chongqing 400037, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Drug Clinical Trial Institution, the Second Affiliated Hospital, Army Medical University, Chongqing 400037, China","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101448461","display_name":"Hongli Zhou","orcid":"https://orcid.org/0000-0002-9774-3577","observed_orcids":["https://orcid.org/0000-0002-9774-3577"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hongli Zhou","raw_affiliation_strings":["National Drug Clinical Trial Institution, the Second Affiliated Hospital, Army Medical University, Chongqing 400037, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Drug Clinical Trial Institution, the Second Affiliated Hospital, Army Medical University, Chongqing 400037, China","institution_ids":["https://openalex.org/I151075929"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5104728972","display_name":"Guisheng Qian","orcid":"https://orcid.org/0000-0002-5538-6460","observed_orcids":["https://orcid.org/0000-0002-5538-6460"]},"institutions":[{"id":"https://openalex.org/I151075929","display_name":"Army Medical University","ror":"https://ror.org/05w21nn13","country_code":"CN","type":"education","lineage":["https://openalex.org/I151075929"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Guisheng Qian","raw_affiliation_strings":["Institute of Respiratory Diseases, the Second Affiliated Hospital, Army Medical University, Chongqing 400037, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Respiratory Diseases, the Second Affiliated Hospital, Army Medical University, Chongqing 400037, China","institution_ids":["https://openalex.org/I151075929"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5104728972"],"corresponding_institution_ids":["https://openalex.org/I151075929"],"apc_list":null,"apc_paid":null,"fwci":2.1657,"has_fulltext":false,"cited_by_count":22,"citation_normalized_percentile":{"value":0.86108247,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":98},"biblio":{"volume":"27","issue":"19","first_page":"3151","last_page":"3167"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10009","display_name":"Dementia and Cognitive Impairment Research","score":0.9634000062942505,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T14144","display_name":"Neurological Disease Mechanisms and Treatments","score":0.023800000548362732,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13077","display_name":"Cancer-related cognitive impairment studies","score":0.0026000000070780516,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetic-cognitive-dysfunction","display_name":"diabetic cognitive dysfunction","score":0.9200000166893005},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9990000128746033},{"id":"https://openalex.org/keywords/short-term-memory-impairment","display_name":"short-term memory impairment","score":0.718999981880188},{"id":"https://openalex.org/keywords/executive-function","display_name":"executive function","score":0.9440000057220459},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.6629999876022339},{"id":"https://openalex.org/keywords/insulin-resistance","display_name":"insulin resistance","score":0.5690000057220459},{"id":"https://openalex.org/keywords/hyperglycemia","display_name":"hyperglycemia","score":0.8500000238418579},{"id":"https://openalex.org/keywords/brain-atrophy","display_name":"brain atrophy","score":0.7429999709129333},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.921999990940094},{"id":"https://openalex.org/keywords/amygdala","display_name":"amygdala","score":0.9150000214576721},{"id":"https://openalex.org/keywords/white-matter","display_name":"white matter","score":0.7080000042915344},{"id":"https://openalex.org/keywords/cerebral-blood-flow","display_name":"cerebral blood flow","score":0.8629999756813049},{"id":"https://openalex.org/keywords/amplitude-of-low-frequency-fluctuation","display_name":"amplitude of low-frequency fluctuation","score":0.8159999847412109},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.8100000023841858},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.7170000076293945},{"id":"https://openalex.org/keywords/neurotransmitter-disorders","display_name":"neurotransmitter disorders","score":0.8429999947547913},{"id":"https://openalex.org/keywords/vascular-disease","display_name":"vascular disease","score":0.6700000166893005},{"id":"https://openalex.org/keywords/hypoglycemia","display_name":"hypoglycemia","score":0.8080000281333923},{"id":"https://openalex.org/keywords/hyperlipidemia","display_name":"hyperlipidemia","score":0.9539999961853027},{"id":"https://openalex.org/keywords/adiposity","display_name":"adiposity","score":0.921999990940094},{"id":"https://openalex.org/keywords/risk-factors","display_name":"risk factors","score":0.6700000166893005},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.7400000095367432},{"id":"https://openalex.org/keywords/animal-models-of-diabetes","display_name":"animal models of diabetes","score":0.6740000247955322},{"id":"https://openalex.org/keywords/neuronal-imaging","display_name":"neuronal imaging","score":0.5680000185966492}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6049230098724365},{"id":"https://openalex.org/C2777391703","wikidata":"https://www.wikidata.org/wiki/Q1053470","display_name":"Insulin resistance","level":3,"score":0.5813785195350647},{"id":"https://openalex.org/C2779632907","wikidata":"https://www.wikidata.org/wiki/Q13444883","display_name":"Brain Structure and Function","level":3,"score":0.5394246578216553},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5372779965400696},{"id":"https://openalex.org/C2779985164","wikidata":"https://www.wikidata.org/wiki/Q5419936","display_name":"Executive dysfunction","level":4,"score":0.4736329913139343},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.4692518711090088},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4284304976463318},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.4201722741127014},{"id":"https://openalex.org/C2781172350","wikidata":"https://www.wikidata.org/wiki/Q194520","display_name":"Atrophy","level":2,"score":0.4163368046283722},{"id":"https://openalex.org/C60644358","wikidata":"https://www.wikidata.org/wiki/Q128570","display_name":"Bioinformatics","level":1,"score":0.4098134934902191},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.39398008584976196},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.38690415024757385},{"id":"https://openalex.org/C14216870","wikidata":"https://www.wikidata.org/wiki/Q3872","display_name":"Neuropsychology","level":3,"score":0.3024524748325348},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.287075400352478},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.22888821363449097},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.12528008222579956},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.09194120764732361}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001921","descriptor_name":"Brain","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003924","descriptor_name":"Diabetes Mellitus, Type 2","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008279","descriptor_name":"Magnetic Resonance Imaging","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D060825","descriptor_name":"Cognitive Dysfunction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.2174/1871530319666190206225635","doi":"https://doi.org/10.2174/1871530319666190206225635","is_oa":false,"landing_page_url":"https://doi.org/10.2174/1871530319666190206225635","pdf_url":null,"source":{"id":"https://openalex.org/S33159018","display_name":"Current Medicinal Chemistry","issn_l":"0929-8673","issn":["0929-8673","1875-533X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320079","host_organization_name":"Bentham Science Publishers","host_organization_lineage":["https://openalex.org/P4310320079"],"host_organization_lineage_names":["Bentham Science Publishers"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current Medicinal Chemistry","raw_type":"journal-article"},{"id":"pmid:30727866","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30727866","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Current medicinal chemistry","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2018616944","display_name":null,"funder_award_id":"81471040","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G2713568621","display_name":null,"funder_award_id":"2015YLC32","funder_id":"https://openalex.org/F4320327581","funder_display_name":"Army Medical University"},{"id":"https://openalex.org/G3066550918","display_name":null,"funder_award_id":"CSTC2016shmszx130006","funder_id":"https://openalex.org/F4320323172","funder_display_name":"Natural Science Foundation of Chongqing"},{"id":"https://openalex.org/G6698239864","display_name":null,"funder_award_id":"81770806","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"},{"id":"https://openalex.org/G8225930547","display_name":null,"funder_award_id":"CSTC2015jcyjB0147","funder_id":"https://openalex.org/F4320323172","funder_display_name":"Natural Science Foundation of Chongqing"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320323172","display_name":"Natural Science Foundation of Chongqing","ror":"https://ror.org/01h0zpd94"},{"id":"https://openalex.org/F4320327581","display_name":"Army Medical University","ror":null}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":158,"referenced_works":["https://openalex.org/W114449514","https://openalex.org/W149971845","https://openalex.org/W203377342","https://openalex.org/W406517605","https://openalex.org/W979768471","https://openalex.org/W1122627960","https://openalex.org/W1451511165","https://openalex.org/W1453012560","https://openalex.org/W1484736336","https://openalex.org/W1527171303","https://openalex.org/W1546858076","https://openalex.org/W1552601391","https://openalex.org/W1577335269","https://openalex.org/W1601933227","https://openalex.org/W1605572142","https://openalex.org/W1649495788","https://openalex.org/W1650293197","https://openalex.org/W1705001022","https://openalex.org/W1718410121","https://openalex.org/W1738493004","https://openalex.org/W1742477308","https://openalex.org/W1749888188","https://openalex.org/W1812387122","https://openalex.org/W1862556966","https://openalex.org/W1911161994","https://openalex.org/W1950655908","https://openalex.org/W1960268562","https://openalex.org/W1964884387","https://openalex.org/W1969034413","https://openalex.org/W1970665848","https://openalex.org/W1971310460","https://openalex.org/W1973162109","https://openalex.org/W1974588388","https://openalex.org/W1980054867","https://openalex.org/W1982795519","https://openalex.org/W1984099286","https://openalex.org/W1985007039","https://openalex.org/W1985693042","https://openalex.org/W1986611187","https://openalex.org/W1988761237","https://openalex.org/W1989104104","https://openalex.org/W1992934050","https://openalex.org/W1994735836","https://openalex.org/W1997366085","https://openalex.org/W1998471569","https://openalex.org/W2002774484","https://openalex.org/W2004349651","https://openalex.org/W2004942012","https://openalex.org/W2006932083","https://openalex.org/W2019724009","https://openalex.org/W2020571042","https://openalex.org/W2021446295","https://openalex.org/W2023210185","https://openalex.org/W2023863507","https://openalex.org/W2024809897","https://openalex.org/W2026283383","https://openalex.org/W2026418993","https://openalex.org/W2027987672","https://openalex.org/W2028600947","https://openalex.org/W2028802753","https://openalex.org/W2028805513","https://openalex.org/W2030265072","https://openalex.org/W2030609731","https://openalex.org/W2033186294","https://openalex.org/W2034932339","https://openalex.org/W2037642562","https://openalex.org/W2037904566","https://openalex.org/W2044733885","https://openalex.org/W2044837319","https://openalex.org/W2046949772","https://openalex.org/W2047662727","https://openalex.org/W2048288736","https://openalex.org/W2059405549","https://openalex.org/W2063206310","https://openalex.org/W2064342657","https://openalex.org/W2066170650","https://openalex.org/W2074153243","https://openalex.org/W2074454567","https://openalex.org/W2078437085","https://openalex.org/W2078850955","https://openalex.org/W2079222945","https://openalex.org/W2082465271","https://openalex.org/W2083880873","https://openalex.org/W2092765147","https://openalex.org/W2094766256","https://openalex.org/W2095738201","https://openalex.org/W2098047743","https://openalex.org/W2099589415","https://openalex.org/W2100605785","https://openalex.org/W2101868057","https://openalex.org/W2103885907","https://openalex.org/W2104901197","https://openalex.org/W2104909085","https://openalex.org/W2106639039","https://openalex.org/W2110350685","https://openalex.org/W2112256576","https://openalex.org/W2113086193","https://openalex.org/W2113736465","https://openalex.org/W2114301383","https://openalex.org/W2115309909","https://openalex.org/W2120568610","https://openalex.org/W2121483283","https://openalex.org/W2122035159","https://openalex.org/W2124138136","https://openalex.org/W2124967984","https://openalex.org/W2126801397","https://openalex.org/W2127951644","https://openalex.org/W2129625339","https://openalex.org/W2130950132","https://openalex.org/W2131565364","https://openalex.org/W2131760568","https://openalex.org/W2132933127","https://openalex.org/W2134243884","https://openalex.org/W2135092775","https://openalex.org/W2135490238","https://openalex.org/W2136520115","https://openalex.org/W2136800398","https://openalex.org/W2137566817","https://openalex.org/W2139377504","https://openalex.org/W2141866284","https://openalex.org/W2143821259","https://openalex.org/W2143907712","https://openalex.org/W2146343703","https://openalex.org/W2147483910","https://openalex.org/W2147945386","https://openalex.org/W2148585875","https://openalex.org/W2150191386","https://openalex.org/W2150472993","https://openalex.org/W2151295407","https://openalex.org/W2151431366","https://openalex.org/W2152409603","https://openalex.org/W2152471765","https://openalex.org/W2152795120","https://openalex.org/W2153022901","https://openalex.org/W2153841141","https://openalex.org/W2154164650","https://openalex.org/W2158742097","https://openalex.org/W2159899308","https://openalex.org/W2160157473","https://openalex.org/W2164581509","https://openalex.org/W2166449272","https://openalex.org/W2169715537","https://openalex.org/W2170736107","https://openalex.org/W2221038835","https://openalex.org/W2229565311","https://openalex.org/W2238329432","https://openalex.org/W2273904707","https://openalex.org/W2275825473","https://openalex.org/W2319272574","https://openalex.org/W2330728276","https://openalex.org/W2402446982","https://openalex.org/W2565243994","https://openalex.org/W2566533773","https://openalex.org/W2572009580","https://openalex.org/W2604150159","https://openalex.org/W2805690900","https://openalex.org/W2810882781","https://openalex.org/W2896139746"],"related_works":["https://openalex.org/W2358046737","https://openalex.org/W2026463240","https://openalex.org/W168169107","https://openalex.org/W2964165734","https://openalex.org/W2473572751","https://openalex.org/W2153444597","https://openalex.org/W2188465516","https://openalex.org/W7197659360","https://openalex.org/W262848366","https://openalex.org/W2165030750"],"abstract_inverted_index":{"Type":[0],"2":[1,29,115],"diabetes":[2,30,116],"increases":[3],"the":[4,11,14,76,80,89,163],"risk":[5,45,144],"of":[6,16,27,75,88,108,113,132,141],"developing":[7],"cognitive":[8,49,71,118,148],"dysfunction":[9,50,72,119],"in":[10,13,37,161],"elderly":[12],"form":[15],"short-term":[17],"memory":[18,42],"and":[19,24,41,61,84,91,101,106,123,130,143,154,166,172],"executive":[20],"function":[21],"impairment.":[22],"Genetic":[23],"diet-induced":[25],"models":[26,158],"type":[28,114],"further":[31,139],"support":[32],"this":[33],"link,":[34],"displaying":[35],"deficits":[36],"working":[38],"memory,":[39],"learning,":[40],"performance.":[43],"The":[44,111],"factors":[46,145],"for":[47,146],"diabetic":[48,68,147],"include":[51],"vascular":[52],"disease,":[53],"hypoglycaemia,":[54],"hyperlipidaemia,":[55],"adiposity,":[56],"insulin":[57,126],"resistance,":[58,127],"lifestyle":[59],"factors,":[60],"genetic":[62],"factors.":[63],"Using":[64],"neuronal":[65,151],"imaging":[66,152],"technologies,":[67],"patients":[69],"with":[70,117],"show":[73],"atrophy":[74],"whole":[77],"brain,":[78],"particularly":[79],"grey":[81],"matter,":[82],"hippocampus":[83],"amygdala;":[85],"increased":[86],"volume":[87],"ventricular":[90],"white":[92],"matter;":[93],"brain":[94],"infarcts;":[95],"impaired":[96],"network":[97],"integrity;":[98],"abnormal":[99],"microstructure;":[100],"reduced":[102],"cerebral":[103],"blood":[104],"flow":[105],"amplitude":[107],"low-frequency":[109],"fluctuations.":[110],"pathogenesis":[112,165],"involves":[120],"hyperglycaemia,":[121],"macrovascular":[122],"microvascular":[124],"diseases,":[125],"inflammation,":[128],"apoptosis,":[129],"disorders":[131],"neurotransmitters.":[133],"Large":[134],"clinical":[135],"trials":[136],"may":[137],"offer":[138],"proof":[140],"biomarkers":[142],"dysfunction.":[149],"Advanced":[150],"technologies":[153],"novel":[155],"disease":[156],"animal":[157],"will":[159],"assist":[160],"elucidating":[162],"precise":[164],"to":[167],"provide":[168],"better":[169],"therapeutic":[170],"interventions":[171],"treatment.":[173]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":6},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-02-21T00:00:00"}
