{"id":"https://openalex.org/W2913278138","doi":"https://doi.org/10.1016/j.eurpsy.2019.01.015","title":"The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors","display_name":"The efficacy of cariprazine in negative symptoms of schizophrenia: Post hoc analyses of PANSS individual items and PANSS-derived factors","publication_year":2019,"publication_date":"2019-02-07","ids":{"openalex":"https://openalex.org/W2913278138","doi":"https://doi.org/10.1016/j.eurpsy.2019.01.015","mag":"2913278138","pmid":"https://pubmed.ncbi.nlm.nih.gov/30738380"},"language":"en","primary_location":{"id":"doi:10.1016/j.eurpsy.2019.01.015","doi":"https://doi.org/10.1016/j.eurpsy.2019.01.015","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.eurpsy.2019.01.015","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/88750B579FEFCD315AEE64425457C9F6/S0924933800009330a.pdf/div-class-title-the-efficacy-of-cariprazine-in-negative-symptoms-of-schizophrenia-post-hoc-analyses-of-panss-individual-items-and-panss-derived-factors-div.pdf","source":{"id":"https://openalex.org/S87202501","display_name":"European Psychiatry","issn_l":"0924-9338","issn":["0924-9338","1778-3585"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Psychiatry","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"hybrid","oa_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/88750B579FEFCD315AEE64425457C9F6/S0924933800009330a.pdf/div-class-title-the-efficacy-of-cariprazine-in-negative-symptoms-of-schizophrenia-post-hoc-analyses-of-panss-individual-items-and-panss-derived-factors-div.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5112081052","display_name":"Wolfgang Fleischhacker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I143397708","display_name":"Innsbruck Medical University","ror":"https://ror.org/03pt86f80","country_code":"AT","type":"education","lineage":["https://openalex.org/I143397708"]},{"id":"https://openalex.org/I190249584","display_name":"Universit\u00e4t Innsbruck","ror":"https://ror.org/054pv6659","country_code":"AT","type":"education","lineage":["https://openalex.org/I190249584"]}],"countries":["AT"],"is_corresponding":false,"raw_author_name":"Wolfgang Fleischhacker","raw_affiliation_strings":["Department of Psychiatry, Psychotherapy and Psychosomatics, Medical University Innsbruck, Innsbruck, Austria","aDepartment of Psychiatry, Psychotherapy and PsychosomaticsMedical University Innsbruck, Innsbruck, Austria"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, Psychotherapy and Psychosomatics, Medical University Innsbruck, Innsbruck, Austria","institution_ids":["https://openalex.org/I143397708","https://openalex.org/I190249584"]},{"raw_affiliation_string":"aDepartment of Psychiatry, Psychotherapy and PsychosomaticsMedical University Innsbruck, Innsbruck, Austria","institution_ids":["https://openalex.org/I143397708","https://openalex.org/I190249584"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032931781","display_name":"Silvana Galderisi","orcid":"https://orcid.org/0000-0002-1592-7656","observed_orcids":["https://orcid.org/0000-0002-1592-7656"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Silvana Galderisi","raw_affiliation_strings":["Department of Psychiatry, University of Naples (SUN), Naples, Italy","bDepartment of Psychiatry, University of Naples (SUN), Naples, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Psychiatry, University of Naples (SUN), Naples, Italy","institution_ids":[]},{"raw_affiliation_string":"bDepartment of Psychiatry, University of Naples (SUN), Naples, Italy","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060763145","display_name":"I. Laszlovszky","orcid":"https://orcid.org/0000-0002-2437-0714","observed_orcids":["https://orcid.org/0000-0002-2437-0714"]},"institutions":[{"id":"https://openalex.org/I2808169635","display_name":"Gedeon Richter (Hungary)","ror":"https://ror.org/0033rtn64","country_code":"HU","type":"company","lineage":["https://openalex.org/I2808169635"]}],"countries":["HU"],"is_corresponding":true,"raw_author_name":"Istv\u00e1n Laszlovszky","raw_affiliation_strings":["Medical Division, Gedeon Richter Plc, Budapest, Hungary. Electronic address: i.laszlovszky@richter.hu","cMedical Division, Gedeon Richter Plc, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Gedeon Richter Plc, Budapest, Hungary. Electronic address: i.laszlovszky@richter.hu","institution_ids":["https://openalex.org/I2808169635"]},{"raw_affiliation_string":"cMedical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102320512","display_name":"B. Szatm\u00e1ri","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2808169635","display_name":"Gedeon Richter (Hungary)","ror":"https://ror.org/0033rtn64","country_code":"HU","type":"company","lineage":["https://openalex.org/I2808169635"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Bal\u00e1zs Szatm\u00e1ri","raw_affiliation_strings":["Medical Division, Gedeon Richter Plc, Budapest, Hungary","cMedical Division, Gedeon Richter Plc, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]},{"raw_affiliation_string":"cMedical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5114214871","display_name":"\u00c1gota Barab\u00e1ssy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2808169635","display_name":"Gedeon Richter (Hungary)","ror":"https://ror.org/0033rtn64","country_code":"HU","type":"company","lineage":["https://openalex.org/I2808169635"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"\u00c1gota Barab\u00e1ssy","raw_affiliation_strings":["Medical Division, Gedeon Richter Plc, Budapest, Hungary","cMedical Division, Gedeon Richter Plc, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]},{"raw_affiliation_string":"cMedical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5034031214","display_name":"K\u00e1roly Acsai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2808169635","display_name":"Gedeon Richter (Hungary)","ror":"https://ror.org/0033rtn64","country_code":"HU","type":"company","lineage":["https://openalex.org/I2808169635"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"K\u00e1roly Acsai","raw_affiliation_strings":["Medical Division, Gedeon Richter Plc, Budapest, Hungary","cMedical Division, Gedeon Richter Plc, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]},{"raw_affiliation_string":"cMedical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013448187","display_name":"Erzs\u00e9bet Szalai","orcid":"https://orcid.org/0009-0006-4322-3433","observed_orcids":["https://orcid.org/0009-0006-4322-3433"]},"institutions":[{"id":"https://openalex.org/I2808169635","display_name":"Gedeon Richter (Hungary)","ror":"https://ror.org/0033rtn64","country_code":"HU","type":"company","lineage":["https://openalex.org/I2808169635"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Erzs\u00e9bet Szalai","raw_affiliation_strings":["Medical Division, Gedeon Richter Plc, Budapest, Hungary","cMedical Division, Gedeon Richter Plc, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]},{"raw_affiliation_string":"cMedical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058881972","display_name":"Judit Hars\u00e1nyi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2808169635","display_name":"Gedeon Richter (Hungary)","ror":"https://ror.org/0033rtn64","country_code":"HU","type":"company","lineage":["https://openalex.org/I2808169635"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Judit Hars\u00e1nyi","raw_affiliation_strings":["Medical Division, Gedeon Richter Plc, Budapest, Hungary","cMedical Division, Gedeon Richter Plc, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]},{"raw_affiliation_string":"cMedical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081268307","display_name":"Willie R. Earley","orcid":"https://orcid.org/0009-0002-3138-0467","observed_orcids":["https://orcid.org/0009-0002-3138-0467"]},"institutions":[{"id":"https://openalex.org/I4210139498","display_name":"Allergan (United States)","ror":"https://ror.org/03pfqk412","country_code":"US","type":"company","lineage":["https://openalex.org/I2948728702","https://openalex.org/I4210139498"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Willie Earley","raw_affiliation_strings":["Allergan, Madison, NJ, USA","dAllergan, Madison, NJ, USA Allergan, MadisonNJUSA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allergan, Madison, NJ, USA","institution_ids":["https://openalex.org/I4210139498"]},{"raw_affiliation_string":"dAllergan, Madison, NJ, USA Allergan, MadisonNJUSA","institution_ids":["https://openalex.org/I4210139498"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072496167","display_name":"Mehul Patel","orcid":"https://orcid.org/0000-0002-5681-5888","observed_orcids":["https://orcid.org/0000-0002-5681-5888","https://orcid.org/0000-0002-1281-3207"]},"institutions":[{"id":"https://openalex.org/I4210139498","display_name":"Allergan (United States)","ror":"https://ror.org/03pfqk412","country_code":"US","type":"company","lineage":["https://openalex.org/I2948728702","https://openalex.org/I4210139498"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mehul Patel","raw_affiliation_strings":["Allergan, Madison, NJ, USA","dAllergan, Madison, NJ, USA Allergan, MadisonNJUSA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Allergan, Madison, NJ, USA","institution_ids":["https://openalex.org/I4210139498"]},{"raw_affiliation_string":"dAllergan, Madison, NJ, USA Allergan, MadisonNJUSA","institution_ids":["https://openalex.org/I4210139498"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5007300327","display_name":"Gy\u00f6rgy N\u00e9meth","orcid":"https://orcid.org/0000-0002-9779-9618","observed_orcids":["https://orcid.org/0000-0002-9779-9618"]},"institutions":[{"id":"https://openalex.org/I2808169635","display_name":"Gedeon Richter (Hungary)","ror":"https://ror.org/0033rtn64","country_code":"HU","type":"company","lineage":["https://openalex.org/I2808169635"]}],"countries":["HU"],"is_corresponding":false,"raw_author_name":"Gy\u00f6rgy N\u00e9meth","raw_affiliation_strings":["Medical Division, Gedeon Richter Plc, Budapest, Hungary","cMedical Division, Gedeon Richter Plc, Budapest, Hungary"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Medical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]},{"raw_affiliation_string":"cMedical Division, Gedeon Richter Plc, Budapest, Hungary","institution_ids":["https://openalex.org/I2808169635"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5060763145"],"corresponding_institution_ids":["https://openalex.org/I2808169635"],"apc_list":{"value":3000,"currency":"USD","value_usd":3000},"apc_paid":{"value":3000,"currency":"USD","value_usd":3000},"fwci":11.8947,"has_fulltext":true,"cited_by_count":115,"citation_normalized_percentile":{"value":0.9920966,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":98,"max":100},"biblio":{"volume":"58","issue":null,"first_page":"1","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology (medical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12308","display_name":"Mental Health and Psychiatry","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1211","display_name":"Philosophy"},"field":{"id":"https://openalex.org/fields/12","display_name":"Arts and Humanities"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cariprazine","display_name":"cariprazine","score":1.0},{"id":"https://openalex.org/keywords/risperidone","display_name":"risperidone","score":0.9319999814033508},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.7770000100135803},{"id":"https://openalex.org/keywords/negative-symptoms","display_name":"negative symptoms","score":0.9829999804496765},{"id":"https://openalex.org/keywords/positive-and-negative-syndrome-scale","display_name":"PANSS","score":0.5550000071525574},{"id":"https://openalex.org/keywords/blunted-affect","display_name":"blunted affect","score":0.7789999842643738},{"id":"https://openalex.org/keywords/emotional-withdrawal","display_name":"emotional withdrawal","score":0.7680000066757202},{"id":"https://openalex.org/keywords/social-withdrawal","display_name":"social withdrawal","score":0.8870000243186951},{"id":"https://openalex.org/keywords/antipsychotic-efficacy","display_name":"antipsychotic efficacy","score":0.746999979019165},{"id":"https://openalex.org/keywords/disorganized-thinking","display_name":"disorganized thinking","score":0.6399999856948853},{"id":"https://openalex.org/keywords/cognition","display_name":"cognition","score":0.4950000047683716}],"concepts":[{"id":"https://openalex.org/C2780057945","wikidata":"https://www.wikidata.org/wiki/Q412443","display_name":"Risperidone","level":3,"score":0.8411020040512085},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.7467046976089478},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.6762767434120178},{"id":"https://openalex.org/C2780135775","wikidata":"https://www.wikidata.org/wiki/Q7233251","display_name":"Positive and Negative Syndrome Scale","level":3,"score":0.587061882019043},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.4917958080768585},{"id":"https://openalex.org/C58732023","wikidata":"https://www.wikidata.org/wiki/Q770260","display_name":"Partial agonist","level":4,"score":0.47834131121635437},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.46798181533813477},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.44458431005477905},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.43308213353157043},{"id":"https://openalex.org/C67761136","wikidata":"https://www.wikidata.org/wiki/Q2105849","display_name":"Post-hoc analysis","level":2,"score":0.4330371618270874},{"id":"https://openalex.org/C2779727114","wikidata":"https://www.wikidata.org/wiki/Q170082","display_name":"Psychosis","level":2,"score":0.3094788193702698},{"id":"https://openalex.org/C2778938600","wikidata":"https://www.wikidata.org/wiki/Q389934","display_name":"Agonist","level":3,"score":0.30073297023773193},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.2137020230293274},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.09885576367378235},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001526","descriptor_name":"Behavioral Symptoms","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D001526","descriptor_name":"Behavioral Symptoms","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010879","descriptor_name":"Piperazines","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000175","qualifier_name":"diagnosis","is_major_topic":false},{"descriptor_ui":"D012559","descriptor_name":"Schizophrenia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D012565","descriptor_name":"Schizophrenic Psychology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014150","descriptor_name":"Antipsychotic Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018967","descriptor_name":"Risperidone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true}],"locations_count":4,"locations":[{"id":"doi:10.1016/j.eurpsy.2019.01.015","doi":"https://doi.org/10.1016/j.eurpsy.2019.01.015","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.eurpsy.2019.01.015","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/88750B579FEFCD315AEE64425457C9F6/S0924933800009330a.pdf/div-class-title-the-efficacy-of-cariprazine-in-negative-symptoms-of-schizophrenia-post-hoc-analyses-of-panss-individual-items-and-panss-derived-factors-div.pdf","source":{"id":"https://openalex.org/S87202501","display_name":"European Psychiatry","issn_l":"0924-9338","issn":["0924-9338","1778-3585"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Psychiatry","raw_type":"journal-article"},{"id":"pmid:30738380","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30738380","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European psychiatry : the journal of the Association of European Psychiatrists","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unicampania.it:11591/408346","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11591/408346","pdf_url":null,"source":{"id":"https://openalex.org/S7407055255","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 degli Studi della Campania \"Luigi Vanvitelli\"","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:zenodo.org:35814","doi":null,"is_oa":true,"landing_page_url":"https://www.openaccessrepository.it/record/35814","pdf_url":null,"source":{"id":"https://openalex.org/S4306402478","display_name":"INFM-OAR (INFN Catania)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210116497","host_organization_name":"Istituto Nazionale di Fisica Nucleare, Sezione di Catania","host_organization_lineage":["https://openalex.org/I4210116497"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":{"id":"doi:10.1016/j.eurpsy.2019.01.015","doi":"https://doi.org/10.1016/j.eurpsy.2019.01.015","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.eurpsy.2019.01.015","pdf_url":"https://www.cambridge.org/core/services/aop-cambridge-core/content/view/88750B579FEFCD315AEE64425457C9F6/S0924933800009330a.pdf/div-class-title-the-efficacy-of-cariprazine-in-negative-symptoms-of-schizophrenia-post-hoc-analyses-of-panss-individual-items-and-panss-derived-factors-div.pdf","source":{"id":"https://openalex.org/S87202501","display_name":"European Psychiatry","issn_l":"0924-9338","issn":["0924-9338","1778-3585"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","oarl","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310311721","host_organization_name":"Cambridge University Press","host_organization_lineage":["https://openalex.org/P4310311721","https://openalex.org/P4310311702"],"host_organization_lineage_names":["Cambridge University Press","University of Cambridge"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"European Psychiatry","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307105","display_name":"Amgen","ror":"https://ror.org/03g03ge92"},{"id":"https://openalex.org/F4320308970","display_name":"Teva Pharmaceutical Industries","ror":"https://ror.org/01wfv3m53"},{"id":"https://openalex.org/F4320321863","display_name":"Gedeon Richter","ror":"https://ror.org/0033rtn64"},{"id":"https://openalex.org/F4320327918","display_name":"H. Lundbeck A/S","ror":"https://ror.org/0564cd633"},{"id":"https://openalex.org/F4320337601","display_name":"Janssen Pharmaceuticals","ror":"https://ror.org/03qd7mz70"},{"id":"https://openalex.org/F4320338413","display_name":"Cilag","ror":"https://ror.org/02fe4h741"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2913278138.pdf","grobid_xml":"https://content.openalex.org/works/W2913278138.grobid-xml"},"referenced_works_count":56,"referenced_works":["https://openalex.org/W18482851","https://openalex.org/W33021784","https://openalex.org/W138237410","https://openalex.org/W1981747359","https://openalex.org/W1993523975","https://openalex.org/W2001166226","https://openalex.org/W2001390449","https://openalex.org/W2001515160","https://openalex.org/W2032292594","https://openalex.org/W2034674874","https://openalex.org/W2050259895","https://openalex.org/W2051869406","https://openalex.org/W2062522511","https://openalex.org/W2065091744","https://openalex.org/W2068363909","https://openalex.org/W2070023870","https://openalex.org/W2073579715","https://openalex.org/W2074914062","https://openalex.org/W2077138902","https://openalex.org/W2088811387","https://openalex.org/W2089011671","https://openalex.org/W2095891895","https://openalex.org/W2096192353","https://openalex.org/W2097757149","https://openalex.org/W2098447482","https://openalex.org/W2100441519","https://openalex.org/W2100557888","https://openalex.org/W2102149537","https://openalex.org/W2110240978","https://openalex.org/W2121313171","https://openalex.org/W2122716896","https://openalex.org/W2125445289","https://openalex.org/W2129951232","https://openalex.org/W2130145042","https://openalex.org/W2131925003","https://openalex.org/W2140606211","https://openalex.org/W2144453507","https://openalex.org/W2147333389","https://openalex.org/W2156601000","https://openalex.org/W2156770514","https://openalex.org/W2159011576","https://openalex.org/W2165379748","https://openalex.org/W2167223183","https://openalex.org/W2171111401","https://openalex.org/W2399624761","https://openalex.org/W2464365852","https://openalex.org/W2514999534","https://openalex.org/W2580975499","https://openalex.org/W2587606972","https://openalex.org/W2588121205","https://openalex.org/W2619718464","https://openalex.org/W2788513991","https://openalex.org/W2795320269","https://openalex.org/W2921520099","https://openalex.org/W3196369884","https://openalex.org/W4248856529"],"related_works":["https://openalex.org/W2349031901","https://openalex.org/W2889080334","https://openalex.org/W2475190820","https://openalex.org/W2617727871","https://openalex.org/W4251413444","https://openalex.org/W4200232543","https://openalex.org/W2724939259","https://openalex.org/W2587606972","https://openalex.org/W4210323406","https://openalex.org/W2728416399"],"abstract_inverted_index":{"BACKGROUND:":[0],"receptor":[1],"partial":[2],"agonist,":[3],"was":[4,79,147,168,174],"significantly":[5,80,175],"more":[6],"effective":[7],"than":[8],"risperidone":[9,72,87,152,180,214],"in":[10,14,19,41,64,82,102,160,231],"treating":[11,232],"negative":[12,26,124,165,202,233],"symptoms":[13,162,234],"a":[15,57],"prospectively":[16],"designed":[17],"trial":[18],"patients":[20],"with":[21],"schizophrenia":[22],"and":[23,47,52,157,221],"persistent,":[24],"predominant":[25],"symptoms.":[27],"METHODS:":[28],"Using":[29],"post":[30],"hoc":[31],"analyses,":[32],"we":[33],"evaluated":[34,128],"change":[35],"from":[36,77,172],"baseline":[37,78,173],"at":[38],"week":[39],"26":[40],"individual":[42],"items":[43,90,199,220],"of":[44,84,113,115,235],"the":[45,65],"Positive":[46],"Negative":[48,132,141,218],"Syndrome":[49],"Scale":[50],"(PANSS)":[51],"PANSS-derived":[53,123,224],"factor":[54,126],"models":[55,127],"using":[56],"mixed-effects":[58],"model":[59],"for":[60,131,149,177,229],"repeated":[61],"measures":[62],"(MMRM)":[63],"intent-to-treat":[66],"(ITT)":[67],"population":[68],"(cariprazine":[69],"=":[70,73],"227;":[71],"227).":[74],"RESULTS:":[75],"Change":[76,171],"different":[81,176,201,207],"favor":[83],"cariprazine":[85,150,178,230],"versus":[86,151,179,213],"on":[88,110,181,215],"PANSS":[89,217],"N1-N5":[91],"(blunted":[92],"affect,":[93],"emotional":[94],"withdrawal,":[95,100],"poor":[96],"rapport,":[97],"passive/apathetic":[98],"social":[99],"difficulty":[101],"abstract":[103],"thinking)":[104],"(P":[105,153],"<":[106,154,195],".05),":[107],"but":[108],"not":[109,169],"N6":[111],"(lack":[112],"spontaneity/flow":[114],"conversation)":[116],"or":[117],"N7":[118],"(stereotyped":[119],"thinking).":[120],"On":[121],"all":[122,223],"symptom":[125,166,187,203],"(PANSS-Factor":[129],"Score":[130],"Symptoms,":[133],"Liemburg":[134],"factors,":[135,137],"Khan":[136],"Pentagonal":[138],"Structure":[139],"Model":[140],"Symptom":[142],"factor),":[143],"statistically":[144],"significant":[145,211],"improvement":[146,167,212],"demonstrated":[148],".01).":[155],"Small":[156],"similar":[158],"changes":[159],"positive/depressive/EPS":[161],"suggested":[163],"that":[164],"pseudospecific.":[170],"PANSS-based":[182],"factors":[183,225],"evaluating":[184],"other":[185],"relevant":[186],"domains":[188],"(disorganized":[189],"thoughts,":[190],"prosocial":[191],"function,":[192],"cognition;":[193],"P":[194],".05).":[196],"CONCLUSIONS:":[197],"Since":[198],"representing":[200],"dimensions":[204],"may":[205],"represent":[206],"fundamental":[208],"pathophysiological":[209],"mechanisms,":[210],"most":[216],"Subscale":[219],"across":[222],"suggests":[226],"broad-spectrum":[227],"efficacy":[228],"schizophrenia.":[236]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":15},{"year":2024,"cited_by_count":24},{"year":2023,"cited_by_count":10},{"year":2022,"cited_by_count":26},{"year":2021,"cited_by_count":19},{"year":2020,"cited_by_count":16}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-02-21T00:00:00"}