{"id":"https://openalex.org/W2913266458","doi":"https://doi.org/10.4103/2347-6486.240240","title":"Electrocardiographic changes in organophosphate poisoning - A prospective study of 50 cases at a tertiary care center in Gujarat","display_name":"Electrocardiographic changes in organophosphate poisoning - A prospective study of 50 cases at a tertiary care center in Gujarat","publication_year":2017,"publication_date":"2017-01-01","ids":{"openalex":"https://openalex.org/W2913266458","doi":"https://doi.org/10.4103/2347-6486.240240","mag":"2913266458"},"language":"en","primary_location":{"id":"doi:10.4103/2347-6486.240240","doi":"https://doi.org/10.4103/2347-6486.240240","is_oa":true,"landing_page_url":"https://doi.org/10.4103/2347-6486.240240","pdf_url":null,"source":{"id":"https://openalex.org/S4210196724","display_name":"Journal of Integrated Health Sciences","issn_l":"2347-6486","issn":["2347-6486","2347-6494"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Integrated Health Sciences","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.4103/2347-6486.240240","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5108760910","display_name":"Sanket G. Makwana","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210115408","display_name":"CU Shah Medical College and Hospital","ror":"https://ror.org/029x1vn55","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210115408"]}],"countries":["IN"],"is_corresponding":true,"raw_author_name":"Sanket Makwana","raw_affiliation_strings":["Assistant Professor, Department of Medicine, C U Shah Medical College, Surendranagar, Gujarat, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Professor, Department of Medicine, C U Shah Medical College, Surendranagar, Gujarat, India","institution_ids":["https://openalex.org/I4210115408"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054420775","display_name":"MN Saiyad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"MN Saiyad","raw_affiliation_strings":["Professor, Department of Medicine, Smt. S C L Municipal General, Ahmedabad, Gujarat, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Professor, Department of Medicine, Smt. S C L Municipal General, Ahmedabad, Gujarat, India","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5061723969","display_name":"Vaishali S Makwana","orcid":"https://orcid.org/0009-0002-4487-6832","observed_orcids":["https://orcid.org/0009-0002-4487-6832"]},"institutions":[{"id":"https://openalex.org/I4210115408","display_name":"CU Shah Medical College and Hospital","ror":"https://ror.org/029x1vn55","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210115408"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Vaishali Makwana","raw_affiliation_strings":["Assistant Professor, Department of Skin &V.D, C U Shah Medical College, Surendranagar, Gujarat, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Assistant Professor, Department of Skin &V.D, C U Shah Medical College, Surendranagar, Gujarat, India","institution_ids":["https://openalex.org/I4210115408"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5108760910"],"corresponding_institution_ids":["https://openalex.org/I4210115408"],"apc_list":null,"apc_paid":null,"fwci":0.4051,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.56823544,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":91,"max":95},"biblio":{"volume":"5","issue":"2","first_page":"18","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.8984000086784363,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.8984000086784363,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.08919999748468399,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13639","display_name":"Paraquat toxicity studies and treatments","score":0.0012000000569969416,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/organophosphate-poisoning","display_name":"organophosphate poisoning","score":1.0},{"id":"https://openalex.org/keywords/electrocardiographic-abnormalities","display_name":"electrocardiographic abnormalities","score":0.9169999957084656},{"id":"https://openalex.org/keywords/cardiac-arrhythmia","display_name":"cardiac arrhythmias","score":0.7519999742507935},{"id":"https://openalex.org/keywords/sinus-tachycardia","display_name":"sinus tachycardia","score":0.953000009059906},{"id":"https://openalex.org/keywords/st-t-wave-changes","display_name":"ST-T changes","score":0.9179999828338623},{"id":"https://openalex.org/keywords/qtc-prolongation","display_name":"QTc prolongation","score":0.996999979019165},{"id":"https://openalex.org/keywords/cholinesterase-inhibitors","display_name":"cholinesterase inhibitors","score":0.8569999933242798},{"id":"https://openalex.org/keywords/suicide-poisoning","display_name":"suicide poisoning","score":0.5099999904632568},{"id":"https://openalex.org/keywords/butyrylcholinesterase","display_name":"butyrylcholinesterase","score":0.7429999709129333},{"id":"https://openalex.org/keywords/cardiac-conduction-disorders","display_name":"cardiac conduction disorders","score":0.460999995470047}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.84136962890625},{"id":"https://openalex.org/C2778736120","wikidata":"https://www.wikidata.org/wiki/Q3153685","display_name":"Organophosphate poisoning","level":4,"score":0.767231822013855},{"id":"https://openalex.org/C2780144208","wikidata":"https://www.wikidata.org/wiki/Q522229","display_name":"Sinus tachycardia","level":2,"score":0.7104393839836121},{"id":"https://openalex.org/C2781235965","wikidata":"https://www.wikidata.org/wiki/Q2995544","display_name":"Sinus bradycardia","level":5,"score":0.660197377204895},{"id":"https://openalex.org/C2780283014","wikidata":"https://www.wikidata.org/wiki/Q209583","display_name":"Tachycardia","level":2,"score":0.5697430372238159},{"id":"https://openalex.org/C2777495988","wikidata":"https://www.wikidata.org/wiki/Q217111","display_name":"Bradycardia","level":4,"score":0.5371094346046448},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.5016400814056396},{"id":"https://openalex.org/C118441451","wikidata":"https://www.wikidata.org/wiki/Q12074763","display_name":"QT interval","level":2,"score":0.5006024837493896},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.49000659584999084},{"id":"https://openalex.org/C2778361543","wikidata":"https://www.wikidata.org/wiki/Q6516941","display_name":"Left axis deviation","level":3,"score":0.4894336760044098},{"id":"https://openalex.org/C2775914520","wikidata":"https://www.wikidata.org/wiki/Q12335414","display_name":"Sinus rhythm","level":3,"score":0.46052345633506775},{"id":"https://openalex.org/C2780040984","wikidata":"https://www.wikidata.org/wiki/Q79785","display_name":"Electrocardiography","level":2,"score":0.42748284339904785},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.41363537311553955},{"id":"https://openalex.org/C2777953023","wikidata":"https://www.wikidata.org/wiki/Q1073121","display_name":"Heart rate","level":3,"score":0.3736954629421234},{"id":"https://openalex.org/C2776588719","wikidata":"https://www.wikidata.org/wiki/Q411097","display_name":"Organophosphate","level":3,"score":0.19511377811431885},{"id":"https://openalex.org/C84393581","wikidata":"https://www.wikidata.org/wiki/Q82642","display_name":"Blood pressure","level":2,"score":0.10591751337051392},{"id":"https://openalex.org/C2779161974","wikidata":"https://www.wikidata.org/wiki/Q815819","display_name":"Atrial fibrillation","level":2,"score":0.0730823278427124},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.0},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.4103/2347-6486.240240","doi":"https://doi.org/10.4103/2347-6486.240240","is_oa":true,"landing_page_url":"https://doi.org/10.4103/2347-6486.240240","pdf_url":null,"source":{"id":"https://openalex.org/S4210196724","display_name":"Journal of Integrated Health Sciences","issn_l":"2347-6486","issn":["2347-6486","2347-6494"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Integrated Health Sciences","raw_type":"journal-article"},{"id":"pmh:oai:doaj.org/article:f9e9b09a49ff43a0a92da1aa13eac276","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/f9e9b09a49ff43a0a92da1aa13eac276","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal of Integrated Health Sciences, Vol 5, Iss 2, Pp 18-24 (2017)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.4103/2347-6486.240240","doi":"https://doi.org/10.4103/2347-6486.240240","is_oa":true,"landing_page_url":"https://doi.org/10.4103/2347-6486.240240","pdf_url":null,"source":{"id":"https://openalex.org/S4210196724","display_name":"Journal of Integrated Health Sciences","issn_l":"2347-6486","issn":["2347-6486","2347-6494"],"is_oa":true,"is_in_doaj":true,"is_core":false,"listed_in":["doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-sa","license_id":"https://openalex.org/licenses/cc-by-nc-sa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Integrated Health Sciences","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3206313458","https://openalex.org/W7015461726","https://openalex.org/W2073641872","https://openalex.org/W2763845719","https://openalex.org/W4232190075","https://openalex.org/W2766270791","https://openalex.org/W2094249923","https://openalex.org/W3128282693","https://openalex.org/W169339293","https://openalex.org/W4414216173"],"abstract_inverted_index":{"Introduction:":[0],"Organophosphates":[1],"(OP)":[2],"are":[3,17],"irreversible":[4],"cholinesterase":[5,115],"inhibitors,":[6],"producing":[7],"nicotinic":[8],"and":[9,62,111,130,133,157,199,218,229],"muscarinic":[10],"effects.":[11],"Cardiac":[12],"complications":[13],"with":[14,44,83,95,203],"these":[15,223],"compounds":[16,205],"often":[18],"fatal.":[19],"Early":[20],"recognition":[21],"of":[22,68,85,119,164,234,237],"abnormal":[23],"rhythm":[24],"protects":[25],"the":[26,39,51,140,235,238,248],"patients":[27,43,239],"against":[28],"acquiring":[29],"life-threatening":[30],"arrhythmias.":[31],"Hence,":[32],"this":[33],"study":[34,67,141],"was":[35,71,105,122,143,149,166,175],"done":[36,123],"to":[37,241,247],"determine":[38,50],"ECG":[40,117,173,209],"findings":[41],"in":[42,58,76,139,178,187],"OP":[45,86,204,242],"poisoning.Aims":[46],"&":[47,55],"Objectives:":[48],"To":[49],"various":[52],"electrocardiographic":[53],"changes":[54,183,217],"its":[56],"importance":[57],"acute":[59],"Organophosphate":[60],"poisoning.Materials":[61],"methods:":[63],"This":[64],"prospective":[65],"observational":[66],"50":[69],"cases":[70,159,169],"conducted":[72],"for":[73,124],"2":[74],"years":[75],"a":[77],"tertiary":[78],"care":[79],"institute.":[80],"All":[81],"adults":[82],"history":[84],"poisoning,":[87],"admitted":[88],"within":[89],"12":[90],"hours":[91],"were":[92,102,152,155],"enrolled.":[93],"Patients":[94],"cardiac":[96,230],"disease":[97],"or":[98],"treated":[99],"from":[100],"outside":[101],"excluded.":[103],"Diagnosis":[104],"made":[106],"by":[107,113,181],"history,":[108],"clinical":[109],"features":[110],"confirmed":[112],"serum":[114],"level.":[116],"analysis":[118],"each":[120],"case":[121],"rate,":[125],"rhythm,":[126],"ST-T":[127,182,216],"changes,":[128],"PR":[129,194],"QTc":[131,185,219],"intervals,":[132],"conduction":[134],"defects":[135],"etc.Results:":[136],"Mean":[137],"age":[138],"group":[142],"30.66":[144],"\u00b1":[145],"11.70(SD).":[146],"Male:Female":[147],"ratio":[148],"1.94:1.":[150],"78%":[151],"suicidal,":[153],"22%":[154],"accidental":[156],"6(12%)":[158],"expired.":[160],"Most":[161,171],"common":[162,172],"mode":[163],"poisoning":[165],"ingestion":[167],"45":[168],"(90%).":[170],"abnormality":[174],"Sinus":[176,189],"Tachycardia":[177],"12(24%)":[179],"followed":[180],"8(16%),":[184],"prolongation":[186],"6(12%),":[188],"Bradycardia":[190],"4(8%),":[191],"Extrasystole":[192],"2(4%),":[193],"Prolongation":[195],"1(2%),":[196],"AF":[197],"1(2%)":[198],"VT":[200],"1(2%).Conclusion:":[201],"Poisoning":[202],"can":[206,225],"produce":[207],"significant":[208],"abnormalities":[210,224],"especially":[211],"sinus":[212],"tachycardia,":[213],"non":[214],"specific":[215],"interval":[220],"prolongation.":[221],"Since":[222],"cause":[226],"lethal":[227],"arrhythmia":[228],"damage,":[231],"careful":[232],"observation":[233],"electrocardiogram":[236],"exposed":[240],"compound":[243],"is":[244],"necessary,":[245],"parallel":[246],"appropriate":[249],"medical":[250],"management.":[251]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2020,"cited_by_count":2}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2019-02-21T00:00:00"}