{"id":"https://openalex.org/W2913146435","doi":"https://doi.org/10.3390/bios9010028","title":"Toward Highly Efficient Cancer Imaging and Therapy Using the Environment-Friendly Chitosan Nanoparticles and NIR Laser","display_name":"Toward Highly Efficient Cancer Imaging and Therapy Using the Environment-Friendly Chitosan Nanoparticles and NIR Laser","publication_year":2019,"publication_date":"2019-02-18","ids":{"openalex":"https://openalex.org/W2913146435","doi":"https://doi.org/10.3390/bios9010028","mag":"2913146435","pmid":"https://pubmed.ncbi.nlm.nih.gov/30781627","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6469023"},"language":"en","primary_location":{"id":"doi:10.3390/bios9010028","doi":"https://doi.org/10.3390/bios9010028","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/bios9010028","pdf_url":"https://www.mdpi.com/2079-6374/9/1/28/pdf?version=1550473832","source":{"id":"https://openalex.org/S150925516","display_name":"Biosensors","issn_l":"2079-6374","issn":["2079-6374"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.mdpi.com/2079-6374/9/1/28/pdf?version=1550473832","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012198335","display_name":"Hala S. Abuelmakarem","orcid":"https://orcid.org/0000-0003-0663-5624","observed_orcids":["https://orcid.org/0000-0003-0663-5624"]},"institutions":[{"id":"https://openalex.org/I4210120363","display_name":"Higher Institute of Engineering","ror":"https://ror.org/02pyw9g57","country_code":"EG","type":"education","lineage":["https://openalex.org/I4210120363"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Hala S. Abuelmakarem","raw_affiliation_strings":["System and Biomedical Engineering Department, The Higher Institute of Engineering, El Shorouk City, Cairo 11837, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"System and Biomedical Engineering Department, The Higher Institute of Engineering, El Shorouk City, Cairo 11837, Egypt","institution_ids":["https://openalex.org/I4210120363"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016150655","display_name":"Mahmoud A. Sliem","orcid":"https://orcid.org/0000-0001-9749-6281","observed_orcids":["https://orcid.org/0000-0001-9749-6281"]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Mahmoud A. Sliem","raw_affiliation_strings":["Department of Laser Applications in Metrology, Photochemistry and Agriculture (LAMPA), National Institute of Laser Enhanced Sciences (NILE), Cairo University, Giza 12613, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Laser Applications in Metrology, Photochemistry and Agriculture (LAMPA), National Institute of Laser Enhanced Sciences (NILE), Cairo University, Giza 12613, Egypt","institution_ids":["https://openalex.org/I145487455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040404708","display_name":"Jala M. El-Azab","orcid":"https://orcid.org/0000-0003-3583-0955","observed_orcids":["https://orcid.org/0000-0003-3583-0955"]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Jala El-Azab","raw_affiliation_strings":["Department of Engineering Applications of Laser, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza 12613, Egypt"],"raw_orcid":"https://orcid.org/0000-0003-3583-0955","affiliations":[{"raw_affiliation_string":"Department of Engineering Applications of Laser, National Institute of Laser Enhanced Sciences (NILES), Cairo University, Giza 12613, Egypt","institution_ids":["https://openalex.org/I145487455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5028960551","display_name":"Moustafa M. A. Farghaly","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120363","display_name":"Higher Institute of Engineering","ror":"https://ror.org/02pyw9g57","country_code":"EG","type":"education","lineage":["https://openalex.org/I4210120363"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Moustafa M. A. Farghaly","raw_affiliation_strings":["System and Biomedical Engineering Department, The Higher Institute of Engineering, El Shorouk City, Cairo 11837, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"System and Biomedical Engineering Department, The Higher Institute of Engineering, El Shorouk City, Cairo 11837, Egypt","institution_ids":["https://openalex.org/I4210120363"]}]},{"author_position":"last","author":{"id":null,"display_name":"Wafaa A. Ahmed","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Wafaa A. Ahmed","raw_affiliation_strings":["Cancer Biology Department, Biochemistry and Molecular Biology Unit, National Cancer Institute, Cairo University, Giza 11796, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cancer Biology Department, Biochemistry and Molecular Biology Unit, National Cancer Institute, Cairo University, Giza 11796, Egypt","institution_ids":["https://openalex.org/I145487455"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5012198335"],"corresponding_institution_ids":["https://openalex.org/I4210120363"],"apc_list":{"value":1000,"currency":"CHF","value_usd":1013},"apc_paid":{"value":1000,"currency":"CHF","value_usd":1013},"fwci":0.8603,"has_fulltext":true,"cited_by_count":22,"citation_normalized_percentile":{"value":0.6731525,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"9","issue":"1","first_page":"28","last_page":"28"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.9688000082969666,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10957","display_name":"Photodynamic Therapy Research Studies","score":0.02070000022649765,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10063","display_name":"Nanoparticle-Based Drug Delivery","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/2502","display_name":"Biomaterials"},"field":{"id":"https://openalex.org/fields/25","display_name":"Materials Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/chitosan-tripolyphosphate-nanoparticles","display_name":"chitosan-tripolyphosphate nanoparticles","score":0.9860000014305115},{"id":"https://openalex.org/keywords/chitosan-nanoparticles","display_name":"chitosan nanoparticles","score":0.9070000052452087},{"id":"https://openalex.org/keywords/near-infrared-laser","display_name":"near-infrared laser","score":0.9520000219345093},{"id":"https://openalex.org/keywords/photothermal-therapy","display_name":"photothermal therapy","score":0.7609999775886536},{"id":"https://openalex.org/keywords/colon-cancer","display_name":"colon cancer","score":0.796999990940094},{"id":"https://openalex.org/keywords/caco-2-cells","display_name":"Caco-2 cells","score":0.9750000238418579},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.9729999899864197},{"id":"https://openalex.org/keywords/tumor-imaging","display_name":"tumor imaging","score":0.7900000214576721},{"id":"https://openalex.org/keywords/photodynamic-therapy","display_name":"photodynamic therapy","score":0.46299999952316284},{"id":"https://openalex.org/keywords/cell-viability","display_name":"cell viability","score":0.4339999854564667}],"concepts":[{"id":"https://openalex.org/C2780070996","wikidata":"https://www.wikidata.org/wiki/Q61482373","display_name":"Trypan blue","level":3,"score":0.8810305595397949},{"id":"https://openalex.org/C86181022","wikidata":"https://www.wikidata.org/wiki/Q196823","display_name":"Zeta potential","level":3,"score":0.8050186038017273},{"id":"https://openalex.org/C109316439","wikidata":"https://www.wikidata.org/wiki/Q246181","display_name":"Cytotoxicity","level":3,"score":0.7515714168548584},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.7318887710571289},{"id":"https://openalex.org/C2779732960","wikidata":"https://www.wikidata.org/wiki/Q408510","display_name":"Chitosan","level":2,"score":0.72516930103302},{"id":"https://openalex.org/C155672457","wikidata":"https://www.wikidata.org/wiki/Q61231","display_name":"Nanoparticle","level":2,"score":0.5590505003929138},{"id":"https://openalex.org/C2780783641","wikidata":"https://www.wikidata.org/wiki/Q738686","display_name":"MTT assay","level":3,"score":0.5491374731063843},{"id":"https://openalex.org/C520434653","wikidata":"https://www.wikidata.org/wiki/Q38867","display_name":"Laser","level":2,"score":0.5036126971244812},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.4632296562194824},{"id":"https://openalex.org/C96232424","wikidata":"https://www.wikidata.org/wiki/Q4118072","display_name":"Cancer cell","level":3,"score":0.4568544030189514},{"id":"https://openalex.org/C160892712","wikidata":"https://www.wikidata.org/wiki/Q901559","display_name":"Fourier transform infrared spectroscopy","level":2,"score":0.45328572392463684},{"id":"https://openalex.org/C14631669","wikidata":"https://www.wikidata.org/wiki/Q896108","display_name":"Dynamic light scattering","level":3,"score":0.42776039242744446},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4130331575870514},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.39418068528175354},{"id":"https://openalex.org/C13965031","wikidata":"https://www.wikidata.org/wiki/Q243545","display_name":"Nuclear chemistry","level":1,"score":0.3743267059326172},{"id":"https://openalex.org/C12554922","wikidata":"https://www.wikidata.org/wiki/Q7100","display_name":"Biophysics","level":1,"score":0.3580487370491028},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.22703692317008972},{"id":"https://openalex.org/C42360764","wikidata":"https://www.wikidata.org/wiki/Q83588","display_name":"Chemical engineering","level":1,"score":0.2153272032737732},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.1719609498977661},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.14937016367912292},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.11541131138801575},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.0972256064414978},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.09158802032470703},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.08844605088233948},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.05272287130355835},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.0},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C127413603","wikidata":"https://www.wikidata.org/wiki/Q11023","display_name":"Engineering","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007834","descriptor_name":"Lasers","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D010316","descriptor_name":"Particle Size","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017550","descriptor_name":"Spectroscopy, Fourier Transform Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018938","descriptor_name":"Caco-2 Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019265","descriptor_name":"Spectroscopy, Near-Infrared","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D020128","descriptor_name":"Inhibitory Concentration 50","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D048271","descriptor_name":"Chitosan","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D053758","descriptor_name":"Nanoparticles","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D053758","descriptor_name":"Nanoparticles","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D055672","descriptor_name":"Static Electricity","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055772","descriptor_name":"Green Chemistry Technology","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.3390/bios9010028","doi":"https://doi.org/10.3390/bios9010028","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/bios9010028","pdf_url":"https://www.mdpi.com/2079-6374/9/1/28/pdf?version=1550473832","source":{"id":"https://openalex.org/S150925516","display_name":"Biosensors","issn_l":"2079-6374","issn":["2079-6374"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5459771","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6469023","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:30781627","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30781627","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:6469023","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC6469023/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors (Basel)","raw_type":"Text"},{"id":"pmh:oai:doaj.org/article:9ee0c774e4a34ffb9691ac5767b70876","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/9ee0c774e4a34ffb9691ac5767b70876","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Biosensors, Vol 9, Iss 1, p 28 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3390/bios9010028","doi":"https://doi.org/10.3390/bios9010028","is_oa":true,"landing_page_url":"http://dx.doi.org/10.3390/bios9010028","pdf_url":"https://www.mdpi.com/2079-6374/9/1/28/pdf?version=1550473832","source":{"id":"https://openalex.org/S150925516","display_name":"Biosensors","issn_l":"2079-6374","issn":["2079-6374"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","medline","norway-1","poland-70","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310310987","host_organization_name":"Multidisciplinary Digital Publishing Institute","host_organization_lineage":["https://openalex.org/P4310310987"],"host_organization_lineage_names":["Multidisciplinary Digital Publishing Institute"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Biosensors","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.979200005531311,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2913146435.pdf","grobid_xml":"https://content.openalex.org/works/W2913146435.grobid-xml"},"referenced_works_count":24,"referenced_works":["https://openalex.org/W1809627704","https://openalex.org/W1983483898","https://openalex.org/W1985613151","https://openalex.org/W1986738467","https://openalex.org/W1995618518","https://openalex.org/W2024100029","https://openalex.org/W2028593763","https://openalex.org/W2044486914","https://openalex.org/W2047568538","https://openalex.org/W2094788147","https://openalex.org/W2125439185","https://openalex.org/W2146595615","https://openalex.org/W2155142470","https://openalex.org/W2253117736","https://openalex.org/W2323081352","https://openalex.org/W2492965413","https://openalex.org/W2496095656","https://openalex.org/W2606270564","https://openalex.org/W2755519984","https://openalex.org/W2769504005","https://openalex.org/W2807727844","https://openalex.org/W4234509136","https://openalex.org/W4285719527","https://openalex.org/W6682768855"],"related_works":["https://openalex.org/W2891598745","https://openalex.org/W4411972643","https://openalex.org/W4315465194","https://openalex.org/W4383812752","https://openalex.org/W4212925265","https://openalex.org/W7066833684","https://openalex.org/W2554177731","https://openalex.org/W3198448263","https://openalex.org/W2922260195","https://openalex.org/W4281741432"],"abstract_inverted_index":{"Chitosan-tripolyphosphate":[0],"nanoparticles":[1],"(C-TPP":[2],"NPs)":[3],"were":[4,50,123],"synthesized":[5,48],"to":[6,27,39,113],"investigate":[7],"their":[8,29],"cytotoxicity":[9,71,93],"against":[10,98],"colon":[11],"cancer":[12,32,45],"cells":[13,121],"(Caco2":[14],"cells)":[15],"in":[16,31],"the":[17,20,35,41,75,79,85,105,119,126],"absence":[18],"and":[19,38,65,78,94],"presence":[21],"of":[22],"a":[23,115],"near-infrared":[24],"(NIR)":[25],"laser":[26,37,43,102],"evaluate":[28,40],"influence":[30],"detection":[33],"using":[34,84],"NIR":[36,42],"on":[44,118],"treatment.":[46],"The":[47,70,109],"NPs":[49,90,111],"characterized":[51],"by":[52,74],"Fourier":[53],"transform":[54],"infrared":[55],"(FT-IR)":[56],"spectroscopy,":[57],"dynamic":[58],"light":[59,117],"scattering":[60],"(DLS),":[61],"zeta":[62],"potential":[63],"(ZP),":[64],"transmission":[66],"electronic":[67],"microscope":[68],"(TEM).":[69],"was":[72,82],"analyzed":[73],"MTT":[76],"test":[77],"cell":[80,96,106],"viability":[81,97,107],"assessed":[83],"Trypan":[86],"blue":[87],"method.":[88],"C-TPP":[89,110],"showed":[91],"increased":[92],"decreased":[95],"Caco2":[99],"cells.":[100],"Upon":[101],"exposure":[103],"only,":[104],"decreased.":[108],"appeared":[112],"have":[114],"shining":[116],"cancerous":[120],"which":[122],"photographed":[124],"under":[125],"inverted":[127],"microscope.":[128]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2019-02-21T00:00:00"}