{"id":"https://openalex.org/W2913003077","doi":"https://doi.org/10.1002/9781118512074.ch50","title":"Eosinophilic Esophagitis","display_name":"Eosinophilic Esophagitis","publication_year":2015,"publication_date":"2015-11-27","ids":{"openalex":"https://openalex.org/W2913003077","doi":"https://doi.org/10.1002/9781118512074.ch50","mag":"2913003077"},"language":"en","primary_location":{"id":"doi:10.1002/9781118512074.ch50","doi":"https://doi.org/10.1002/9781118512074.ch50","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781118512074.ch50","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yamada' s Textbook of Gastroenterology","raw_type":"other"},"volume":{"id":"https://openalex.org/W2315731380","display_name":"Yamada' s Textbook of Gastroenterology"},"type":"other","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Yael Haberman Ziv","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yael Haberman Ziv","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058290389","display_name":"Margaret H. Collins","orcid":"https://orcid.org/0000-0002-0756-5974","observed_orcids":["https://orcid.org/0000-0002-0756-5974"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Margaret H. Collins","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I1285204247"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5100715040","display_name":"Marc E. Rothenberg","orcid":"https://orcid.org/0000-0001-9790-6332","observed_orcids":["https://orcid.org/0000-0001-9790-6332"]},"institutions":[{"id":"https://openalex.org/I1285204247","display_name":"Cincinnati Children's Hospital Medical Center","ror":"https://ror.org/01hcyya48","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1285204247"]},{"id":"https://openalex.org/I63135867","display_name":"University of Cincinnati","ror":"https://ror.org/01e3m7079","country_code":"US","type":"education","lineage":["https://openalex.org/I63135867"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Marc E. Rothenberg","raw_affiliation_strings":["Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA","University of Cincinnati College of Medicine, Cincinnati, OH, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I1285204247"]},{"raw_affiliation_string":"University of Cincinnati College of Medicine, Cincinnati, OH, USA","institution_ids":["https://openalex.org/I63135867"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"929","last_page":"936"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12538","display_name":"Eosinophilic Esophagitis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12538","display_name":"Eosinophilic Esophagitis","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2715","display_name":"Gastroenterology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/eosinophilic-esophagitis","display_name":"eosinophilic esophagitis","score":1.0},{"id":"https://openalex.org/keywords/eosinophilic-inflammation","display_name":"eosinophilic inflammation","score":0.6869999766349792},{"id":"https://openalex.org/keywords/ige-mediated-food-allergy","display_name":"IgE-mediated food allergy","score":0.8889999985694885},{"id":"https://openalex.org/keywords/esophageal-biopsy","display_name":"esophageal biopsy","score":0.8059999942779541},{"id":"https://openalex.org/keywords/endoscopic-dilation","display_name":"endoscopic dilation","score":0.6359999775886536},{"id":"https://openalex.org/keywords/drug-therapy","display_name":"pharmacotherapy","score":0.5239999890327454},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.8309999704360962},{"id":"https://openalex.org/keywords/etiology","display_name":"etiology","score":0.5180000066757202}],"concepts":[{"id":"https://openalex.org/C2781065132","wikidata":"https://www.wikidata.org/wiki/Q2057356","display_name":"Eosinophilic esophagitis","level":3,"score":0.965368926525116},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.5710388422012329},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.4933444559574127},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3889305293560028},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3589497208595276},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.08127665519714355}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9781118512074.ch50","doi":"https://doi.org/10.1002/9781118512074.ch50","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781118512074.ch50","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Yamada' s Textbook of Gastroenterology","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":136,"referenced_works":["https://openalex.org/W40765902","https://openalex.org/W1482383475","https://openalex.org/W1512168554","https://openalex.org/W1512442169","https://openalex.org/W1515144800","https://openalex.org/W1606940682","https://openalex.org/W1827033120","https://openalex.org/W1874552489","https://openalex.org/W1964917813","https://openalex.org/W1966625631","https://openalex.org/W1967595860","https://openalex.org/W1967712610","https://openalex.org/W1967926844","https://openalex.org/W1968335934","https://openalex.org/W1969154910","https://openalex.org/W1972578247","https://openalex.org/W1973716304","https://openalex.org/W1975480455","https://openalex.org/W1985242752","https://openalex.org/W1985871702","https://openalex.org/W1987251700","https://openalex.org/W1990648330","https://openalex.org/W1990686783","https://openalex.org/W1995481725","https://openalex.org/W2000093261","https://openalex.org/W2004216239","https://openalex.org/W2005895346","https://openalex.org/W2007253398","https://openalex.org/W2008514990","https://openalex.org/W2009016013","https://openalex.org/W2012891487","https://openalex.org/W2013765121","https://openalex.org/W2013785184","https://openalex.org/W2016423387","https://openalex.org/W2016474236","https://openalex.org/W2016919782","https://openalex.org/W2016952830","https://openalex.org/W2018058053","https://openalex.org/W2019205829","https://openalex.org/W2019870550","https://openalex.org/W2019910323","https://openalex.org/W2021881000","https://openalex.org/W2025232239","https://openalex.org/W2025605750","https://openalex.org/W2027664223","https://openalex.org/W2028134353","https://openalex.org/W2028343710","https://openalex.org/W2028843964","https://openalex.org/W2031806278","https://openalex.org/W2032419156","https://openalex.org/W2033306128","https://openalex.org/W2033559734","https://openalex.org/W2033805821","https://openalex.org/W2034453465","https://openalex.org/W2036399312","https://openalex.org/W2037823168","https://openalex.org/W2037836883","https://openalex.org/W2039350065","https://openalex.org/W2040288515","https://openalex.org/W2040605890","https://openalex.org/W2042800126","https://openalex.org/W2044562596","https://openalex.org/W2045156833","https://openalex.org/W2046529338","https://openalex.org/W2050056753","https://openalex.org/W2051107234","https://openalex.org/W2053292331","https://openalex.org/W2054929272","https://openalex.org/W2056122337","https://openalex.org/W2057085451","https://openalex.org/W2059837927","https://openalex.org/W2063222469","https://openalex.org/W2063910688","https://openalex.org/W2066819964","https://openalex.org/W2069157452","https://openalex.org/W2070330822","https://openalex.org/W2072174334","https://openalex.org/W2072314285","https://openalex.org/W2072705074","https://openalex.org/W2076394214","https://openalex.org/W2077275658","https://openalex.org/W2077290680","https://openalex.org/W2079587357","https://openalex.org/W2083838472","https://openalex.org/W2085080095","https://openalex.org/W2085909033","https://openalex.org/W2087770516","https://openalex.org/W2088661593","https://openalex.org/W2089217846","https://openalex.org/W2090616685","https://openalex.org/W2091168975","https://openalex.org/W2094798162","https://openalex.org/W2097346494","https://openalex.org/W2098145607","https://openalex.org/W2098392838","https://openalex.org/W2099865106","https://openalex.org/W2101870314","https://openalex.org/W2106068114","https://openalex.org/W2114111732","https://openalex.org/W2114578979","https://openalex.org/W2114726031","https://openalex.org/W2116575182","https://openalex.org/W2117153870","https://openalex.org/W2117673476","https://openalex.org/W2124164203","https://openalex.org/W2127288475","https://openalex.org/W2127435005","https://openalex.org/W2127482775","https://openalex.org/W2131870779","https://openalex.org/W2132665714","https://openalex.org/W2139142626","https://openalex.org/W2139719760","https://openalex.org/W2141701917","https://openalex.org/W2142379908","https://openalex.org/W2142760199","https://openalex.org/W2143133632","https://openalex.org/W2144846148","https://openalex.org/W2154263136","https://openalex.org/W2156797817","https://openalex.org/W2159553688","https://openalex.org/W2161107181","https://openalex.org/W2161447951","https://openalex.org/W2165557514","https://openalex.org/W2166893697","https://openalex.org/W2168900215","https://openalex.org/W2323763104","https://openalex.org/W2326465921","https://openalex.org/W2330980996","https://openalex.org/W2911614448","https://openalex.org/W2978498167","https://openalex.org/W4230976467","https://openalex.org/W4232067156","https://openalex.org/W4245181308","https://openalex.org/W4246100030","https://openalex.org/W4253225200","https://openalex.org/W4313309880"],"related_works":["https://openalex.org/W4387606603","https://openalex.org/W2022360765","https://openalex.org/W2966425905","https://openalex.org/W2991348204","https://openalex.org/W2016736983","https://openalex.org/W2319928747","https://openalex.org/W2118992216","https://openalex.org/W4302615698","https://openalex.org/W1995481725","https://openalex.org/W1912264194"],"abstract_inverted_index":{"Eosinophilic":[0],"esophagitis":[1],"(EoE)":[2],"is":[3,8,30,35,115,133],"a":[4,73,87,106],"clinicopathological":[5],"condition":[6],"that":[7,37,41,55,90],"commonly":[9],"recognized":[10],"among":[11],"both":[12],"pediatric":[13],"and":[14,20,61,65,77,96,112,125,128,136,144],"adult":[15],"patients":[16,82,102],"presenting":[17],"to":[18,45],"allergy":[19,60,94],"gastroenterology":[21],"clinics":[22],"throughout":[23],"the":[24,39,46],"world.":[25],"The":[26],"etiology":[27],"of":[28,48,75,81,108,120],"EoE":[29,42,68,85,121],"poorly":[31],"understood,":[32],"but":[33],"evidence":[34],"accumulating":[36],"supports":[38],"concept":[40],"arises":[43],"secondarily":[44],"interplay":[47],"genetic":[49],"features,":[50],"host":[51],"immune":[52],"system":[53],"responses":[54],"include":[56],"pure":[57],"IgE-mediated":[58],"food":[59,110],"cellular-mediated":[62],"hypersensitivity":[63],"disorders,":[64],"environmental":[66],"factors.":[67],"should":[69],"be":[70],"diagnosed":[71],"through":[72],"combination":[74],"clinical":[76],"pathological":[78],"findings.":[79],"Assessment":[80],"with":[83,98,103],"suspected":[84],"requires":[86],"multicomponent":[88],"process":[89],"includes":[91,122],"an":[92],"extensive":[93],"evaluation":[95],"endoscopy":[97],"esophageal":[99],"biopsy.":[100],"For":[101],"atopic":[104],"EoE,":[105],"trial":[107],"specific":[109],"allergen":[111],"aeroallergen":[113],"avoidance":[114],"often":[116],"indicated.":[117],"Current":[118],"management":[119],"endoscopic":[123,129],"evaluations":[124],"dietary,":[126],"pharmacological,":[127],"interventions;":[130],"ongoing":[131],"research":[132],"investigating":[134],"known":[135],"newly":[137],"identified":[138],"factors":[139],"as":[140],"potential":[141],"future":[142],"biomarkers":[143],"therapeutic":[145],"targets":[146],"for":[147],"EoE.":[148]},"counts_by_year":[],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2019-02-21T00:00:00"}
