{"id":"https://openalex.org/W2912990339","doi":"https://doi.org/10.1200/po.18.00235","title":"Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease","display_name":"Detection of Circulating Tumor DNA in Patients With Leiomyosarcoma With Progressive Disease","publication_year":2019,"publication_date":"2019-01-24","ids":{"openalex":"https://openalex.org/W2912990339","doi":"https://doi.org/10.1200/po.18.00235","mag":"2912990339","pmid":"https://pubmed.ncbi.nlm.nih.gov/30793095","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6380497"},"language":"en","primary_location":{"id":"doi:10.1200/po.18.00235","doi":"https://doi.org/10.1200/po.18.00235","is_oa":false,"landing_page_url":"https://doi.org/10.1200/po.18.00235","pdf_url":null,"source":{"id":"https://openalex.org/S4210227748","display_name":"JCO Precision Oncology","issn_l":"2473-4284","issn":["2473-4284"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCO Precision Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6380497","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5011165297","display_name":"Matthew L. Hemming","orcid":"https://orcid.org/0000-0003-4674-7778","observed_orcids":["https://orcid.org/0000-0003-4674-7778"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Matthew L. Hemming","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065388955","display_name":"Kelly S. Klega","orcid":"https://orcid.org/0000-0002-3424-2003","observed_orcids":["https://orcid.org/0000-0002-3424-2003"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kelly Klega","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5082843187","display_name":"Justin Rhoades","orcid":"https://orcid.org/0000-0002-0630-908X","observed_orcids":["https://orcid.org/0000-0002-0630-908X"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Justin Rhoades","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039343639","display_name":"Gavin Ha","orcid":"https://orcid.org/0000-0001-7578-7272","observed_orcids":["https://orcid.org/0000-0001-7578-7272"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gavin Ha","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5059269135","display_name":"Kate E. Acker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kate E. Acker","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110596174","display_name":"Jessica L. Andersen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jessica L. Andersen","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080358469","display_name":"Edwin Thai","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Edwin Thai","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033316770","display_name":"Anwesha Nag","orcid":"https://orcid.org/0000-0002-1947-7429","observed_orcids":["https://orcid.org/0000-0002-1947-7429"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Anwesha Nag","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050754309","display_name":"Aaron R. Thorner","orcid":"https://orcid.org/0000-0002-9160-7881","observed_orcids":["https://orcid.org/0000-0002-9160-7881"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Aaron R. Thorner","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5056266239","display_name":"Chandrajit P. Raut","orcid":"https://orcid.org/0000-0001-7297-3221","observed_orcids":["https://orcid.org/0000-0001-7297-3221"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Chandrajit P. Raut","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5078289621","display_name":"Suzanne George","orcid":"https://orcid.org/0000-0002-1284-8493","observed_orcids":["https://orcid.org/0000-0002-1284-8493","https://orcid.org/0000-0002-8777-8530"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Suzanne George","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5009997118","display_name":"Brian D. Crompton","orcid":"https://orcid.org/0000-0001-9404-6621","observed_orcids":["https://orcid.org/0000-0001-9404-6621"]},"institutions":[{"id":"https://openalex.org/I107606265","display_name":"Broad Institute","ror":"https://ror.org/05a0ya142","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I107606265"]},{"id":"https://openalex.org/I1283280774","display_name":"Brigham and Women's Hospital","ror":"https://ror.org/04b6nzv94","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I121934306","https://openalex.org/I1283280774","https://openalex.org/I48633490"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]},{"id":"https://openalex.org/I4210166317","display_name":"Dana-Farber/Boston Children's Cancer and Blood Disorders Center","ror":"https://ror.org/05k11pb55","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113","https://openalex.org/I4210117453","https://openalex.org/I4210166317"]},{"id":"https://openalex.org/I63966007","display_name":"Massachusetts Institute of Technology","ror":"https://ror.org/042nb2s44","country_code":"US","type":"education","lineage":["https://openalex.org/I63966007"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Brian D. Crompton","raw_affiliation_strings":["Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Matthew L. Hemming, Edwin Thai, Anwesha Nag, and Aaron R. Thorner, Dana-Farber Cancer Institute; Matthew L. Hemming, Kate E. Acker, Jessica L. Andersen, and Suzanne George, Dana-Farber Cancer Institute, Harvard Medical School; Kelly Klega and Brian D. Crompton, Dana-Farber/Boston Children's Cancer and Blood Disorders Center; Chandrajit P. Raut, Brigham and Women\u2019s Hospital, Harvard Medical School, Boston; Justin Rhoades and Brian D. Crompton, Broad Institute of Massachusetts Institute of Technology and","institution_ids":["https://openalex.org/I107606265","https://openalex.org/I1283280774","https://openalex.org/I136199984","https://openalex.org/I4210117453","https://openalex.org/I4210166317","https://openalex.org/I63966007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.5033,"has_fulltext":false,"cited_by_count":59,"citation_normalized_percentile":{"value":0.90635277,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"2019","issue":"3","first_page":"1","last_page":"11"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.8647000193595886,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","score":0.8647000193595886,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10253","display_name":"Sarcoma Diagnosis and Treatment","score":0.12630000710487366,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12820","display_name":"Chromatin Remodeling and Cancer","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/leiomyosarcoma","display_name":"leiomyosarcoma","score":0.9810000061988831},{"id":"https://openalex.org/keywords/circulating-tumor-dna","display_name":"circulating tumor DNA","score":0.9929999709129333},{"id":"https://openalex.org/keywords/cell-free-dna","display_name":"cell-free DNA","score":0.8669999837875366},{"id":"https://openalex.org/keywords/liquid-biopsy","display_name":"liquid biopsy","score":0.9049999713897705},{"id":"https://openalex.org/keywords/copy-number-alterations","display_name":"copy number alterations","score":0.921999990940094},{"id":"https://openalex.org/keywords/tumor-burden","display_name":"tumor burden","score":0.4580000042915344},{"id":"https://openalex.org/keywords/disease-progression","display_name":"disease progression","score":0.8899999856948853},{"id":"https://openalex.org/keywords/uterine-leiomyosarcoma","display_name":"uterine leiomyosarcoma","score":0.8970000147819519},{"id":"https://openalex.org/keywords/tumor-size","display_name":"tumor size","score":0.5},{"id":"https://openalex.org/keywords/recurrence","display_name":"recurrence","score":0.6480000019073486},{"id":"https://openalex.org/keywords/smooth-muscle-tumor","display_name":"smooth muscle tumor","score":0.5830000042915344},{"id":"https://openalex.org/keywords/biomarkers","display_name":"biomarkers","score":0.34299999475479126}],"concepts":[{"id":"https://openalex.org/C2777532014","wikidata":"https://www.wikidata.org/wiki/Q1504713","display_name":"Leiomyosarcoma","level":2,"score":0.637901782989502},{"id":"https://openalex.org/C48126324","wikidata":"https://www.wikidata.org/wiki/Q5276136","display_name":"Digital polymerase chain reaction","level":4,"score":0.585728645324707},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5628146529197693},{"id":"https://openalex.org/C152110520","wikidata":"https://www.wikidata.org/wiki/Q14225730","display_name":"Cell-free fetal DNA","level":5,"score":0.5610290169715881},{"id":"https://openalex.org/C51679486","wikidata":"https://www.wikidata.org/wiki/Q380546","display_name":"DNA sequencing","level":3,"score":0.5560886263847351},{"id":"https://openalex.org/C2778822529","wikidata":"https://www.wikidata.org/wiki/Q1951525","display_name":"Progressive disease","level":3,"score":0.5289872884750366},{"id":"https://openalex.org/C2781335228","wikidata":"https://www.wikidata.org/wiki/Q19596321","display_name":"Circulating tumor DNA","level":3,"score":0.5243233442306519},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.491210401058197},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.46048247814178467},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.4581031799316406},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.4409765303134918},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4346466660499573},{"id":"https://openalex.org/C120821319","wikidata":"https://www.wikidata.org/wiki/Q1501491","display_name":"Copy-number variation","level":4,"score":0.42205560207366943},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4135768413543701},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4076758027076721},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.40121346712112427},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3850209712982178},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.31839823722839355},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.2954097390174866},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.24593418836593628},{"id":"https://openalex.org/C49105822","wikidata":"https://www.wikidata.org/wiki/Q176996","display_name":"Polymerase chain reaction","level":3,"score":0.19444379210472107},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.17199835181236267},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.0},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.0},{"id":"https://openalex.org/C2778258057","wikidata":"https://www.wikidata.org/wiki/Q1136569","display_name":"Prenatal diagnosis","level":4,"score":0.0}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.1200/po.18.00235","doi":"https://doi.org/10.1200/po.18.00235","is_oa":false,"landing_page_url":"https://doi.org/10.1200/po.18.00235","pdf_url":null,"source":{"id":"https://openalex.org/S4210227748","display_name":"JCO Precision Oncology","issn_l":"2473-4284","issn":["2473-4284"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-20","russia-white-list-2"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCO Precision Oncology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5367437","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6380497","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6380497","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6380497","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCO Precis Oncol","raw_type":"Text"},{"id":"pmid:30793095","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30793095","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"JCO precision oncology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:5367437","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6380497","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[{"id":"https://openalex.org/G5316474424","display_name":"Targeting FAK and integrin signaling in preclinical models of Ewing sarcoma","funder_award_id":"K08CA188073","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":35,"referenced_works":["https://openalex.org/W1965054867","https://openalex.org/W1971876346","https://openalex.org/W2004001144","https://openalex.org/W2016796510","https://openalex.org/W2020953583","https://openalex.org/W2029535019","https://openalex.org/W2048513224","https://openalex.org/W2082063053","https://openalex.org/W2103441770","https://openalex.org/W2104793343","https://openalex.org/W2119180969","https://openalex.org/W2119679072","https://openalex.org/W2121110176","https://openalex.org/W2129429170","https://openalex.org/W2131256900","https://openalex.org/W2150962472","https://openalex.org/W2157852151","https://openalex.org/W2167432016","https://openalex.org/W2168133698","https://openalex.org/W2171237493","https://openalex.org/W2256401105","https://openalex.org/W2468983064","https://openalex.org/W2547843406","https://openalex.org/W2590954301","https://openalex.org/W2734691271","https://openalex.org/W2765435739","https://openalex.org/W2765468373","https://openalex.org/W2766493195","https://openalex.org/W2771572701","https://openalex.org/W2775816941","https://openalex.org/W2782274603","https://openalex.org/W2782477516","https://openalex.org/W2791859308","https://openalex.org/W2832813378","https://openalex.org/W2888384864"],"related_works":["https://openalex.org/W2890552559","https://openalex.org/W4410812789","https://openalex.org/W4312226753","https://openalex.org/W2980725675","https://openalex.org/W4280604565","https://openalex.org/W4282978996","https://openalex.org/W2907068181","https://openalex.org/W4409624278","https://openalex.org/W3182346472","https://openalex.org/W2972224380"],"abstract_inverted_index":{"PURPOSE:":[0],"Leiomyosarcoma":[1],"(LMS)":[2],"is":[3],"a":[4,36,228,237,240],"soft":[5],"tissue":[6],"sarcoma":[7],"characterized":[8],"by":[9,76,100,227],"multiple":[10],"copy":[11],"number":[12],"alterations":[13],"(CNAs)":[14],"and":[15,63,91,97,117,134,176,186,191,210,244,255,275,278],"without":[16],"common":[17],"recurrent":[18,192],"single":[19],"nucleotide":[20],"variants.":[21],"We":[22,121],"evaluated":[23,71],"the":[24,88,105,151],"feasibility":[25],"of":[26,38,49,107,127,153,166,204,242,249],"detecting":[27],"circulating":[28],"tumor":[29,43,98,136,174,253],"DNA":[30,59,66,96,99,169],"(ctDNA)":[31],"with":[32,40,74,131,143,172,252],"next-generation":[33],"sequencing":[34,81,231],"in":[35,60,94,125,188,207,216,262],"cohort":[37],"patients":[39,73,129,142],"LMS":[41,75,123,197],"whose":[42],"burden":[44,116,137,149],"ranged":[45],"from":[46,67,72],"no":[47,160],"evidence":[48],"disease":[50,115,132,145,148,177,206,214,256,273],"to":[51,87,103,113,158,268],"metastatic":[52],"progressive":[53,205],"disease.":[54],"PATIENTS":[55],"AND":[56],"METHODS:":[57],"Cell-free":[58],"plasma":[61],"samples":[62],"paired":[64],"genomic":[65],"resected":[68],"tumors":[69,185],"were":[70,85,111,156,181,194],"ultra-low":[77],"passage":[78],"whole":[79],"genome":[80,90],"(ULP-WGS).":[82],"Sequencing":[83],"reads":[84],"aligned":[86],"human":[89],"CNAs":[92,180,193],"identified":[93,122],"cell-free":[95,168],"ichorCNA":[101],"software":[102],"determine":[104],"presence":[106],"ctDNA.":[108,162],"Clinical":[109],"data":[110],"reviewed":[112],"assess":[114],"clinicopathologic":[118],"features.":[119],"RESULTS:":[120],"ctDNA":[124,164,187,199,250],"eleven":[126],"sixteen":[128],"(69%)":[130],"progression":[133],"total":[135,167],"over":[138],"5":[139],"cm.":[140],"Sixteen":[141],"stable":[144],"or":[146],"low":[147],"at":[150],"time":[152],"blood":[154],"draw":[155],"found":[157,182,195],"have":[159],"detectable":[161,212],"Higher":[163,247],"fraction":[165],"was":[170],"associated":[171],"increasing":[173],"size":[175,254],"progression.":[178,257],"Conserved":[179],"between":[183],"primary":[184],"each":[189],"case,":[190],"across":[196],"samples.":[198],"levels":[200,248],"declined":[201],"following":[202],"resection":[203],"one":[208],"case":[209],"became":[211],"upon":[213],"relapse":[215],"another":[217],"individual":[218],"patient.":[219],"CONCLUSION:":[220],"These":[221],"results":[222],"suggest":[223],"that":[224],"ctDNA,":[225],"assayed":[226],"widely":[229],"available":[230],"approach,":[232],"may":[233,260],"be":[234],"useful":[235],"as":[236],"biomarker":[238],"for":[239,272],"subset":[241],"uterine":[243],"extrauterine":[245],"LMS.":[246],"correlate":[251],"Liquid":[258],"biopsies":[259],"assist":[261],"guiding":[263],"treatment":[264],"decisions,":[265],"monitoring":[266],"response":[267],"systemic":[269],"therapy,":[270],"surveying":[271],"recurrence":[274],"differentiating":[276],"benign":[277],"malignant":[279],"smooth":[280],"muscle":[281],"tumors.":[282]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":9},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":11},{"year":2022,"cited_by_count":11},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":5},{"year":2017,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-02-21T00:00:00"}
