{"id":"https://openalex.org/W2912976351","doi":"https://doi.org/10.1016/j.jaci.2018.12.959","title":"PVX108 Peptide Immunotherapy Significantly Reduces Markers of Peanut-Induced Anaphylaxis in a Dose-Dependent Manner","display_name":"PVX108 Peptide Immunotherapy Significantly Reduces Markers of Peanut-Induced Anaphylaxis in a Dose-Dependent Manner","publication_year":2019,"publication_date":"2019-02-01","ids":{"openalex":"https://openalex.org/W2912976351","doi":"https://doi.org/10.1016/j.jaci.2018.12.959","mag":"2912976351"},"language":"en","primary_location":{"id":"doi:10.1016/j.jaci.2018.12.959","doi":"https://doi.org/10.1016/j.jaci.2018.12.959","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2018.12.959","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"},"volume":null,"type":"conference-abstract","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049871340","display_name":"Sudeshna Dhar","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I59293822","display_name":"St. Joseph\u2019s Healthcare Hamilton","ror":"https://ror.org/009z39p97","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I59293822"]},{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Sudeshna Dhar","raw_affiliation_strings":["McMaster University, Hamilton, ON, Canada; St. Joseph's Healthcare, Hamilton, ON, Canada","McMaster University, Hamilton, ON, Canada","St. Joseph's Healthcare, Hamilton, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McMaster University, Hamilton, ON, Canada; St. Joseph's Healthcare, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I59293822","https://openalex.org/I98251732"]},{"raw_affiliation_string":"McMaster University, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I98251732"]},{"raw_affiliation_string":"St. Joseph's Healthcare, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I59293822"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5077280281","display_name":"Mark Larch\u00e9","orcid":"https://orcid.org/0000-0002-1439-7593","observed_orcids":["https://orcid.org/0000-0002-1439-7593"]},"institutions":[{"id":"https://openalex.org/I59293822","display_name":"St. Joseph\u2019s Healthcare Hamilton","ror":"https://ror.org/009z39p97","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I59293822"]},{"id":"https://openalex.org/I98251732","display_name":"McMaster University","ror":"https://ror.org/02fa3aq29","country_code":"CA","type":"education","lineage":["https://openalex.org/I98251732"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Mark Larch\u00e9","raw_affiliation_strings":["McMaster University/St. Joseph's Healthcare, Hamilton, ON, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"McMaster University/St. Joseph's Healthcare, Hamilton, ON, Canada","institution_ids":["https://openalex.org/I59293822","https://openalex.org/I98251732"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3550,"currency":"USD","value_usd":3550},"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"143","issue":"2","first_page":"AB426","last_page":"AB426"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10634","display_name":"Food Allergy and Anaphylaxis Research","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10877","display_name":"Allergic Rhinitis and Sensitization","score":0.0034000000450760126,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/peptide-immunotherapy","display_name":"peptide immunotherapy","score":0.9509999752044678},{"id":"https://openalex.org/keywords/peanut-allergy","display_name":"peanut allergy","score":0.9900000095367432},{"id":"https://openalex.org/keywords/anaphylaxis","display_name":"anaphylaxis","score":0.8159999847412109},{"id":"https://openalex.org/keywords/t-cell-epitopes","display_name":"T cell epitopes","score":0.9390000104904175},{"id":"https://openalex.org/keywords/dose-dependent-efficacy","display_name":"dose-dependent efficacy","score":0.48399999737739563},{"id":"https://openalex.org/keywords/vaccine-safety","display_name":"vaccine safety","score":0.7070000171661377}],"concepts":[{"id":"https://openalex.org/C2775933838","wikidata":"https://www.wikidata.org/wiki/Q168800","display_name":"Anaphylaxis","level":3,"score":0.838299036026001},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7613352537155151},{"id":"https://openalex.org/C27081682","wikidata":"https://www.wikidata.org/wiki/Q269829","display_name":"Placebo","level":3,"score":0.686702311038971},{"id":"https://openalex.org/C2778012357","wikidata":"https://www.wikidata.org/wiki/Q7157933","display_name":"Peanut allergy","level":4,"score":0.5395466685295105},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.5274648666381836},{"id":"https://openalex.org/C207480886","wikidata":"https://www.wikidata.org/wiki/Q42982","display_name":"Allergy","level":2,"score":0.5239558219909668},{"id":"https://openalex.org/C2780510475","wikidata":"https://www.wikidata.org/wiki/Q186752","display_name":"Allergen","level":3,"score":0.4845384955406189},{"id":"https://openalex.org/C197934379","wikidata":"https://www.wikidata.org/wiki/Q2047938","display_name":"Adverse effect","level":2,"score":0.466548889875412},{"id":"https://openalex.org/C2780959883","wikidata":"https://www.wikidata.org/wiki/Q111146","display_name":"Hematocrit","level":2,"score":0.4339660108089447},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4218232333660126},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.41432344913482666},{"id":"https://openalex.org/C2776027960","wikidata":"https://www.wikidata.org/wiki/Q769815","display_name":"Food allergy","level":3,"score":0.35153865814208984},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.10315093398094177},{"id":"https://openalex.org/C204787440","wikidata":"https://www.wikidata.org/wiki/Q188504","display_name":"Alternative medicine","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/j.jaci.2018.12.959","doi":"https://doi.org/10.1016/j.jaci.2018.12.959","is_oa":false,"landing_page_url":"https://doi.org/10.1016/j.jaci.2018.12.959","pdf_url":null,"source":{"id":"https://openalex.org/S108525051","display_name":"Journal of Allergy and Clinical Immunology","issn_l":"0091-6749","issn":["0091-6749","1085-8725","1097-6825"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Allergy and Clinical Immunology","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2013384545","https://openalex.org/W4389949429","https://openalex.org/W2914611256","https://openalex.org/W2265332461","https://openalex.org/W7036095936","https://openalex.org/W1997665131","https://openalex.org/W4323533483","https://openalex.org/W2496156608","https://openalex.org/W2902001080","https://openalex.org/W4414619451"],"abstract_inverted_index":null,"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1}],"updated_date":"2026-09-27T08:07:27.782135","created_date":"2019-02-21T00:00:00"}