{"id":"https://openalex.org/W2912969401","doi":"https://doi.org/10.1016/j.pedneo.2019.01.010","title":"Effect of packed red blood cell transfusion on IL-8 and sICAM-1 in premature neonates at different postnatal ages","display_name":"Effect of packed red blood cell transfusion on IL-8 and sICAM-1 in premature neonates at different postnatal ages","publication_year":2019,"publication_date":"2019-01-30","ids":{"openalex":"https://openalex.org/W2912969401","doi":"https://doi.org/10.1016/j.pedneo.2019.01.010","mag":"2912969401","pmid":"https://pubmed.ncbi.nlm.nih.gov/30824363"},"language":"en","primary_location":{"id":"doi:10.1016/j.pedneo.2019.01.010","doi":"https://doi.org/10.1016/j.pedneo.2019.01.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.pedneo.2019.01.010","pdf_url":null,"source":{"id":"https://openalex.org/S183831342","display_name":"Pediatrics & Neonatology","issn_l":"1875-9572","issn":["1875-9572","2212-1692"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","medline","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics & Neonatology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://doi.org/10.1016/j.pedneo.2019.01.010","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110793538","display_name":"Lamiaa Mohsen","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210164576","display_name":"Cairo University hospitals","ror":"https://ror.org/058djb788","country_code":"EG","type":"healthcare","lineage":["https://openalex.org/I4210164576"]},{"id":"https://openalex.org/I4405261678","display_name":"New Giza University","ror":"https://ror.org/05p2jc137","country_code":"EG","type":"education","lineage":["https://openalex.org/I4405261678"]}],"countries":["EG"],"is_corresponding":false,"raw_author_name":"Lamiaa Mohsen","raw_affiliation_strings":["Department of Neonatology, Faculty of Medicine, Cairo University Hospitals, Egypt; Faculty of Medicine, New Giza University, Cairo, Egypt. Electronic address: Lamiaa7777@yahoo.com","Department of Neonatology, Faculty of Medicine, Cairo University Hospitals, Egypt","Faculty of Medicine, New Giza University, Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Faculty of Medicine, Cairo University Hospitals, Egypt; Faculty of Medicine, New Giza University, Cairo, Egypt. Electronic address: Lamiaa7777@yahoo.com","institution_ids":["https://openalex.org/I4210164576","https://openalex.org/I4405261678"]},{"raw_affiliation_string":"Department of Neonatology, Faculty of Medicine, Cairo University Hospitals, Egypt","institution_ids":["https://openalex.org/I4210164576"]},{"raw_affiliation_string":"Faculty of Medicine, New Giza University, Cairo, Egypt","institution_ids":["https://openalex.org/I4405261678"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108087719","display_name":"Hala Youssef","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131959","display_name":"National Research Centre","ror":"https://ror.org/02n85j827","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210131959"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Hala Youssef","raw_affiliation_strings":["Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt. Electronic address: dr.hala_youssef@hotmail.com","Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt. Electronic address: dr.hala_youssef@hotmail.com","institution_ids":["https://openalex.org/I4210131959"]},{"raw_affiliation_string":"Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt","institution_ids":["https://openalex.org/I4210131959"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Hala Abdelrahman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Hala Abdelrahman","raw_affiliation_strings":["Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt. Electronic address: halahelmi@hotmail.com","Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt. Electronic address: halahelmi@hotmail.com","institution_ids":["https://openalex.org/I145487455"]},{"raw_affiliation_string":"Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt","institution_ids":["https://openalex.org/I145487455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011605245","display_name":"Rabab El Hawary","orcid":"https://orcid.org/0000-0001-6244-0288","observed_orcids":["https://orcid.org/0000-0001-6244-0288"]},"institutions":[{"id":"https://openalex.org/I145487455","display_name":"Cairo University","ror":"https://ror.org/03q21mh05","country_code":"EG","type":"education","lineage":["https://openalex.org/I145487455"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Rabab El Hawary","raw_affiliation_strings":["Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt. Electronic address: rabab_elhawary@hotmail.com","Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt. Electronic address: rabab_elhawary@hotmail.com","institution_ids":["https://openalex.org/I145487455"]},{"raw_affiliation_string":"Clinical and Chemical Pathology Department, Faculty of Medicine, Cairo University, Egypt","institution_ids":["https://openalex.org/I145487455"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027826397","display_name":"Abeer Selim","orcid":"https://orcid.org/0000-0003-1952-4341","observed_orcids":["https://orcid.org/0000-0003-1952-4341"]},"institutions":[{"id":"https://openalex.org/I4210131959","display_name":"National Research Centre","ror":"https://ror.org/02n85j827","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210131959"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Abeer Selim","raw_affiliation_strings":["Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt. Electronic address: abeerselim2004@yahoo.com","Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt"],"raw_orcid":"https://orcid.org/0000-0003-1952-4341","affiliations":[{"raw_affiliation_string":"Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt. Electronic address: abeerselim2004@yahoo.com","institution_ids":["https://openalex.org/I4210131959"]},{"raw_affiliation_string":"Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt","institution_ids":["https://openalex.org/I4210131959"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029611018","display_name":"Safwat A. Aly","orcid":"https://orcid.org/0000-0002-1823-453X","observed_orcids":["https://orcid.org/0000-0002-1823-453X"]},"institutions":[{"id":"https://openalex.org/I2801317318","display_name":"Hospital for Sick Children","ror":"https://ror.org/057q4rt57","country_code":"CA","type":"healthcare","lineage":["https://openalex.org/I2801317318"]}],"countries":["CA"],"is_corresponding":true,"raw_author_name":"Safwat Aly","raw_affiliation_strings":["Department of Pediatric Cardiology, Hospital for Sick Children, Toronto, Canada. Electronic address: safwataly36@gmail.com","Department of Pediatric Cardiology, Hospital for Sick Children, Toronto, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Cardiology, Hospital for Sick Children, Toronto, Canada. Electronic address: safwataly36@gmail.com","institution_ids":["https://openalex.org/I2801317318"]},{"raw_affiliation_string":"Department of Pediatric Cardiology, Hospital for Sick Children, Toronto, Canada","institution_ids":["https://openalex.org/I2801317318"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039222030","display_name":"Mustafa Nada","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210131959","display_name":"National Research Centre","ror":"https://ror.org/02n85j827","country_code":"EG","type":"facility","lineage":["https://openalex.org/I4210131959"]}],"countries":["EG"],"is_corresponding":true,"raw_author_name":"Mustafa Nada","raw_affiliation_strings":["Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt. Electronic address: dr.mostafa.abdelkader@hotmail.com","Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt. Electronic address: dr.mostafa.abdelkader@hotmail.com","institution_ids":["https://openalex.org/I4210131959"]},{"raw_affiliation_string":"Pediatrics Department, Medical Research Division and Medical Research Centre of Excellence (MRCE), National Research Centre, Cairo, Egypt","institution_ids":["https://openalex.org/I4210131959"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5081153018","display_name":"Hany Z. Aly","orcid":"https://orcid.org/0000-0001-7395-6394","observed_orcids":["https://orcid.org/0000-0001-7395-6394"]},"institutions":[{"id":"https://openalex.org/I1316902750","display_name":"Cleveland Clinic","ror":"https://ror.org/03xjacd83","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316902750"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Hany Aly","raw_affiliation_strings":["Department of Neonatology, Cleveland Clinic Children's Hospital, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neonatology, Cleveland Clinic Children's Hospital, USA","institution_ids":["https://openalex.org/I1316902750"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5011605245","https://openalex.org/A5027826397","https://openalex.org/A5029611018","https://openalex.org/A5039222030","https://openalex.org/A5108087719"],"corresponding_institution_ids":["https://openalex.org/I145487455","https://openalex.org/I2801317318","https://openalex.org/I4210131959"],"apc_list":{"value":0,"currency":"USD","value_usd":0},"apc_paid":null,"fwci":0.5478,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.66477456,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"60","issue":"5","first_page":"537","last_page":"542"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10693","display_name":"Blood transfusion and management","score":0.9951000213623047,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12068","display_name":"Neonatal Health and Biochemistry","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/packed-red-blood-cell-transfusion","display_name":"packed red blood cell transfusion","score":0.9409999847412109},{"id":"https://openalex.org/keywords/transfusion-related-immunomodulation","display_name":"transfusion-related immunomodulation","score":0.968999981880188},{"id":"https://openalex.org/keywords/interleukin-8","display_name":"interleukin-8","score":0.9520000219345093},{"id":"https://openalex.org/keywords/soluble-icam-1","display_name":"soluble ICAM-1","score":0.8859999775886536},{"id":"https://openalex.org/keywords/preterm-infants","display_name":"preterm infants","score":0.7789999842643738},{"id":"https://openalex.org/keywords/postnatal-age","display_name":"postnatal age","score":0.8560000061988831},{"id":"https://openalex.org/keywords/pro-inflammatory-cytokines","display_name":"inflammatory cytokines","score":0.7609999775886536}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8664913773536682},{"id":"https://openalex.org/C2778376644","wikidata":"https://www.wikidata.org/wiki/Q2253111","display_name":"Gestational age","level":3,"score":0.6426199674606323},{"id":"https://openalex.org/C2780920261","wikidata":"https://www.wikidata.org/wiki/Q1363810","display_name":"Packed red blood cells","level":3,"score":0.5787609219551086},{"id":"https://openalex.org/C2780014101","wikidata":"https://www.wikidata.org/wiki/Q183605","display_name":"Blood transfusion","level":2,"score":0.42499756813049316},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.40090397000312805},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.38554930686950684},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.33057036995887756},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.1305844783782959},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0713336169719696},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005865","descriptor_name":"Gestational Age","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007234","descriptor_name":"Infant, Premature","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016209","descriptor_name":"Interleukin-8","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D017707","descriptor_name":"Erythrocyte Transfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D018799","descriptor_name":"Intercellular Adhesion Molecule-1","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":true},{"descriptor_ui":"D056747","descriptor_name":"Immunomodulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1016/j.pedneo.2019.01.010","doi":"https://doi.org/10.1016/j.pedneo.2019.01.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.pedneo.2019.01.010","pdf_url":null,"source":{"id":"https://openalex.org/S183831342","display_name":"Pediatrics & Neonatology","issn_l":"1875-9572","issn":["1875-9572","2212-1692"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","medline","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics & Neonatology","raw_type":"journal-article"},{"id":"pmid:30824363","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30824363","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics and neonatology","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:f28e351bedf544b5b1760935d919926e","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/f28e351bedf544b5b1760935d919926e","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Pediatrics and Neonatology, Vol 60, Iss 5, Pp 537-542 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1016/j.pedneo.2019.01.010","doi":"https://doi.org/10.1016/j.pedneo.2019.01.010","is_oa":true,"landing_page_url":"https://doi.org/10.1016/j.pedneo.2019.01.010","pdf_url":null,"source":{"id":"https://openalex.org/S183831342","display_name":"Pediatrics & Neonatology","issn_l":"1875-9572","issn":["1875-9572","2212-1692"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-b","doyens","jufo-1","medline","poland-70","russia-white-list-2"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatrics & Neonatology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":1.0}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[{"id":"https://openalex.org/F4320321148","display_name":"Cairo University","ror":"https://ror.org/03q21mh05"},{"id":"https://openalex.org/F4320327825","display_name":"Jiangsu National Synergistic Innovation Center for Advanced Materials","ror":"https://ror.org/05nzc1r88"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":25,"referenced_works":["https://openalex.org/W1576188136","https://openalex.org/W1577680781","https://openalex.org/W1610045869","https://openalex.org/W1841040774","https://openalex.org/W1976592464","https://openalex.org/W1981897333","https://openalex.org/W1996802813","https://openalex.org/W2020345920","https://openalex.org/W2029853383","https://openalex.org/W2030399686","https://openalex.org/W2039306491","https://openalex.org/W2076488402","https://openalex.org/W2077421523","https://openalex.org/W2081151924","https://openalex.org/W2081281044","https://openalex.org/W2082133962","https://openalex.org/W2082157478","https://openalex.org/W2084456377","https://openalex.org/W2086770834","https://openalex.org/W2091977122","https://openalex.org/W2105475359","https://openalex.org/W2153450942","https://openalex.org/W2154141105","https://openalex.org/W2561840348","https://openalex.org/W4298285345"],"related_works":["https://openalex.org/W2020345920","https://openalex.org/W2132426724","https://openalex.org/W2918214093","https://openalex.org/W2025798168","https://openalex.org/W2592451124","https://openalex.org/W2079508191","https://openalex.org/W3045370953","https://openalex.org/W2474969557","https://openalex.org/W2912539217","https://openalex.org/W4226059648"],"abstract_inverted_index":{"BACKGROUND:":[0],"Transfusion-related":[1],"immunomodulation":[2],"(TRIM)":[3],"has":[4],"been":[5],"described":[6],"in":[7,12,39,46,79,130,144,152,163,174,180,253,258,270,277,303],"adults;":[8],"however,":[9],"its":[10],"existence":[11],"neonates":[13],"is":[14,21],"not":[15,162,195,225,294],"confirmed.":[16],"The":[17,107],"generation":[18],"of":[19,26,75,98,104,109,127,188,221],"TRIM":[20,45],"attributed":[22,284],"to":[23,36,89,285],"increased":[24],"concentrations":[25,108,187,199,220],"IL-8,":[27,40],"sICAM-1":[28,41,112,172],"and":[29,62,101,111,129,192,208,274],"other":[30,229],"pro-inflammatory":[31],"cytokines.":[32],"This":[33,262,291],"study":[34,263,292],"aimed":[35],"monitor":[37],"changes":[38],"as":[42,238,240],"markers":[43],"for":[44,300],"premature":[47],"infants":[48,55,280],"at":[49],"different":[50],"postnatal":[51,91,96],"ages.":[52],"METHODS:":[53],"Preterm":[54],"with":[56,95,149,178,227],"a":[57],"gestational":[58],"age":[59],"between":[60,267],"28":[61,73],"32":[63],"weeks":[64],"who":[65],"were":[66,77,83,113],"receiving":[67],"PRBC":[68],"transfusion":[69,128,257,272,276],"during":[70,230],"the":[71,80,125,131,139,145,175,219,271,289],"first":[72],"days":[74,100],"life":[76],"included":[78],"study.":[81],"Infants":[82],"stratified":[84],"into":[85,138],"two":[86],"groups":[87],"according":[88],"their":[90],"age:":[92],"Group":[93,102,153,164,184,217,278],"1":[94,165],"ages":[97],"(0-14)":[99],"2":[103,154,279],"(15-28)":[105],"days.":[106],"IL-8":[110,142,268],"measured":[114],"by":[115],"enzyme-linked":[116],"immunosorbent":[117],"assay":[118],"(ELISA)":[119],"before":[120,136],"transfusion,":[121],"6":[122],"h":[123],"after":[124,256],"end":[126],"donor's":[132],"PRBCs":[133,146],"bag":[134,176,273],"immediately":[135],"infusion":[137],"baby.":[140],"RESULTS:":[141],"concentration":[143,173,269],"bags":[147],"correlated":[148,177],"post-transfusion":[150,198,241],"level":[151],"(r":[155,166,202,232,242],"=":[156,159,167,170,203,206,210,213,233,236,243,246],"0.59,":[157],"p":[158,169,205,212,235,245],"0.002)":[160],"but":[161],"0.39,":[168],"0.06).":[171],"infants'concentrations":[179],"neither":[181],"group.":[182,260],"In":[183,216],"1,":[185],"pre-transfusion":[186,231],"both":[189,222],"cytokines":[190,223,255],"(IL-8":[191],"sICAM-1)":[193],"did":[194,200,224],"correlate":[196,201,226],"whereas":[197],"-0.09,":[204],"0.68":[207],"r":[209],"0.4,":[211],"0.05":[214],"respectively).":[215],"2,":[218],"each":[228,259],"0.11,":[234],"0.58)":[237],"well":[239],"0.12,":[244],"0.56).":[247],"There":[248],"was":[249],"no":[250],"significant":[251],"increase":[252],"either":[254],"CONCLUSION:":[261],"showed":[264],"positive":[265],"correlation":[266],"post":[275],"which":[281],"could":[282],"be":[283],"passive":[286],"transmission":[287],"from":[288],"bags.":[290],"does":[293],"support":[295],"an":[296],"immune":[297],"modulatory":[298],"effect":[299],"packed":[301],"RBC":[302],"preterm":[304],"infants.":[305]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2019-02-21T00:00:00"}