{"id":"https://openalex.org/W2912835554","doi":"https://doi.org/10.3389/fncel.2019.00031","title":"Suicide and Microglia: Recent Findings and Future Perspectives Based on Human Studies","display_name":"Suicide and Microglia: Recent Findings and Future Perspectives Based on Human Studies","publication_year":2019,"publication_date":"2019-02-13","ids":{"openalex":"https://openalex.org/W2912835554","doi":"https://doi.org/10.3389/fncel.2019.00031","mag":"2912835554","pmid":"https://pubmed.ncbi.nlm.nih.gov/30814929","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/6381042"},"language":"en","primary_location":{"id":"doi:10.3389/fncel.2019.00031","doi":"https://doi.org/10.3389/fncel.2019.00031","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncel.2019.00031","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncel.2019.00031/pdf","source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://www.frontiersin.org/articles/10.3389/fncel.2019.00031/pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5000844496","display_name":"Hisaomi Suzuki","orcid":"https://orcid.org/0009-0007-6193-1510","observed_orcids":["https://orcid.org/0009-0007-6193-1510"]},"institutions":[{"id":"https://openalex.org/I4405283135","display_name":"National Hospital Organization Shimofusa Psychiatric Medical Center","ror":"https://ror.org/012herh49","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4405283135"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Hisaomi Suzuki","raw_affiliation_strings":["National Hospital Organization Shimofusa Psychiatric Medical Center, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Hospital Organization Shimofusa Psychiatric Medical Center, Chiba, Japan","institution_ids":["https://openalex.org/I4405283135"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052182246","display_name":"Masahiro Ohgidani","orcid":"https://orcid.org/0009-0008-9352-7958","observed_orcids":["https://orcid.org/0009-0008-9352-7958","https://orcid.org/0000-0002-5358-5060"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masahiro Ohgidani","raw_affiliation_strings":["Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5053837114","display_name":"Nobuki Kuwano","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Nobuki Kuwano","raw_affiliation_strings":["Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113603598","display_name":"Fabrice Chr\u00e9tien","orcid":"https://orcid.org/0000-0002-2794-1383","observed_orcids":["https://orcid.org/0000-0002-2794-1383"]},"institutions":[{"id":"https://openalex.org/I157536573","display_name":"Institut Pasteur","ror":"https://ror.org/0495fxg12","country_code":"FR","type":"nonprofit","lineage":["https://openalex.org/I157536573"]},{"id":"https://openalex.org/I4210124863","display_name":"Centre Hospitalier Sainte-Anne","ror":"https://ror.org/02kxjxy06","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210124863"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Fabrice Chr\u00e9tien","raw_affiliation_strings":["Human Histopathology and Animal Models Laboratory, Institute Pasteur, Paris, France","Neuropathology Department, Sainte-Anne Hospital, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Human Histopathology and Animal Models Laboratory, Institute Pasteur, Paris, France","institution_ids":["https://openalex.org/I157536573"]},{"raw_affiliation_string":"Neuropathology Department, Sainte-Anne Hospital, Paris, France","institution_ids":["https://openalex.org/I4210124863"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5080651297","display_name":"Geoffroy Lorin de la Grandmaison","orcid":"https://orcid.org/0000-0002-1681-2746","observed_orcids":["https://orcid.org/0000-0002-1681-2746"]},"institutions":[{"id":"https://openalex.org/I4210134648","display_name":"H\u00f4pital Raymond-Poincar\u00e9","ror":"https://ror.org/03pef0w96","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210097159","https://openalex.org/I4210134648"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Geoffroy Lorin de la Grandmaison","raw_affiliation_strings":["Department of Pathology and Forensic Medicine, Raymond Poincar\u00e9 University Hospital, Garches, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology and Forensic Medicine, Raymond Poincar\u00e9 University Hospital, Garches, France","institution_ids":["https://openalex.org/I4210134648"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5006864791","display_name":"Mitsumoto Onaya","orcid":"https://orcid.org/0009-0000-4104-5035","observed_orcids":["https://orcid.org/0009-0000-4104-5035"]},"institutions":[{"id":"https://openalex.org/I4405283135","display_name":"National Hospital Organization Shimofusa Psychiatric Medical Center","ror":"https://ror.org/012herh49","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4405283135"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Mitsumoto Onaya","raw_affiliation_strings":["National Hospital Organization Shimofusa Psychiatric Medical Center, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Hospital Organization Shimofusa Psychiatric Medical Center, Chiba, Japan","institution_ids":["https://openalex.org/I4405283135"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062799763","display_name":"Itaru Tominaga","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405283135","display_name":"National Hospital Organization Shimofusa Psychiatric Medical Center","ror":"https://ror.org/012herh49","country_code":"JP","type":"healthcare","lineage":["https://openalex.org/I4210137409","https://openalex.org/I4405283135"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Itaru Tominaga","raw_affiliation_strings":["National Hospital Organization Shimofusa Psychiatric Medical Center, Chiba, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"National Hospital Organization Shimofusa Psychiatric Medical Center, Chiba, Japan","institution_ids":["https://openalex.org/I4405283135"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5052476480","display_name":"Daiki Setoyama","orcid":"https://orcid.org/0000-0002-4514-7546","observed_orcids":["https://orcid.org/0000-0002-4514-7546"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Daiki Setoyama","raw_affiliation_strings":["Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110716341","display_name":"Dongchon Kang","orcid":"https://orcid.org/0009-0009-4607-3380","observed_orcids":["https://orcid.org/0009-0009-4607-3380"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Dongchon Kang","raw_affiliation_strings":["Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Clinical Chemistry and Laboratory Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033519257","display_name":"Masaru Mimura","orcid":"https://orcid.org/0000-0002-3874-5273","observed_orcids":["https://orcid.org/0000-0002-3874-5273"]},"institutions":[{"id":"https://openalex.org/I203951103","display_name":"Keio University","ror":"https://ror.org/02kn6nx58","country_code":"JP","type":"education","lineage":["https://openalex.org/I203951103"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Masaru Mimura","raw_affiliation_strings":["Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan","institution_ids":["https://openalex.org/I203951103"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5091472205","display_name":"Shigenobu Kanba","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"Shigenobu Kanba","raw_affiliation_strings":["Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5035087249","display_name":"Takahiro A. Kato","orcid":"https://orcid.org/0000-0001-5169-2930","observed_orcids":["https://orcid.org/0000-0001-5169-2930","https://orcid.org/0000-0002-8343-8037"]},"institutions":[{"id":"https://openalex.org/I135598925","display_name":"Kyushu University","ror":"https://ror.org/00p4k0j84","country_code":"JP","type":"education","lineage":["https://openalex.org/I135598925"]}],"countries":["JP"],"is_corresponding":true,"raw_author_name":"Takahiro A. Kato","raw_affiliation_strings":["Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuropsychiatry, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan","institution_ids":["https://openalex.org/I135598925"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":6,"corresponding_author_ids":["https://openalex.org/A5035087249"],"corresponding_institution_ids":["https://openalex.org/I135598925"],"apc_list":{"value":2950,"currency":"USD","value_usd":2950},"apc_paid":{"value":2950,"currency":"USD","value_usd":2950},"fwci":13.0516,"has_fulltext":true,"cited_by_count":201,"citation_normalized_percentile":{"value":0.99703264,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":96,"max":100},"biblio":{"volume":"13","issue":null,"first_page":"31","last_page":"31"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.7925000190734863,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11337","display_name":"Tryptophan and brain disorders","score":0.7925000190734863,"subfield":{"id":"https://openalex.org/subfields/2803","display_name":"Biological Psychiatry"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10376","display_name":"Suicide and Self-Harm Studies","score":0.19449999928474426,"subfield":{"id":"https://openalex.org/subfields/3203","display_name":"Clinical Psychology"},"field":{"id":"https://openalex.org/fields/32","display_name":"Psychology"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11266","display_name":"Neuroinflammation and Neurodegeneration Mechanisms","score":0.008100000210106373,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/suicide","display_name":"suicide","score":0.9990000128746033},{"id":"https://openalex.org/keywords/microglia","display_name":"microglia","score":0.9919999837875366},{"id":"https://openalex.org/keywords/neuroinflammation","display_name":"neuroinflammation","score":0.7919999957084656},{"id":"https://openalex.org/keywords/kynurenine-pathway","display_name":"kynurenine pathway","score":0.9890000224113464},{"id":"https://openalex.org/keywords/suicidal-ideation","display_name":"suicidal ideation","score":0.9539999961853027},{"id":"https://openalex.org/keywords/suicide-related-behaviors","display_name":"suicide-related behaviors","score":0.8050000071525574},{"id":"https://openalex.org/keywords/positron-emission-tomography","display_name":"positron emission tomography","score":0.8080000281333923},{"id":"https://openalex.org/keywords/blood-biomarkers","display_name":"blood biomarkers","score":0.8399999737739563},{"id":"https://openalex.org/keywords/mental-disorders","display_name":"mental illness","score":0.5529999732971191},{"id":"https://openalex.org/keywords/depression","display_name":"depression","score":0.6439999938011169},{"id":"https://openalex.org/keywords/schizophrenia","display_name":"schizophrenia","score":0.9909999966621399}],"concepts":[{"id":"https://openalex.org/C2779830541","wikidata":"https://www.wikidata.org/wiki/Q1622829","display_name":"Microglia","level":3,"score":0.6951701045036316},{"id":"https://openalex.org/C2776641880","wikidata":"https://www.wikidata.org/wiki/Q944142","display_name":"Suicidal ideation","level":4,"score":0.6862343549728394},{"id":"https://openalex.org/C2776412080","wikidata":"https://www.wikidata.org/wiki/Q7431605","display_name":"Schizophrenia (object-oriented programming)","level":2,"score":0.5956946611404419},{"id":"https://openalex.org/C2776710720","wikidata":"https://www.wikidata.org/wiki/Q80417","display_name":"Kynurenine pathway","level":5,"score":0.5841683149337769},{"id":"https://openalex.org/C118552586","wikidata":"https://www.wikidata.org/wiki/Q7867","display_name":"Psychiatry","level":1,"score":0.5697446465492249},{"id":"https://openalex.org/C2781197716","wikidata":"https://www.wikidata.org/wiki/Q864574","display_name":"Biomarker","level":2,"score":0.5177525877952576},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.4577424228191376},{"id":"https://openalex.org/C2776867660","wikidata":"https://www.wikidata.org/wiki/Q1814941","display_name":"Depression (economics)","level":2,"score":0.4545549154281616},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.4498995840549469},{"id":"https://openalex.org/C2777670902","wikidata":"https://www.wikidata.org/wiki/Q492038","display_name":"Human brain","level":2,"score":0.4405202865600586},{"id":"https://openalex.org/C2780051608","wikidata":"https://www.wikidata.org/wiki/Q42844","display_name":"Major depressive disorder","level":3,"score":0.432588130235672},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.40725696086883545},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.3705403208732605},{"id":"https://openalex.org/C70410870","wikidata":"https://www.wikidata.org/wiki/Q199906","display_name":"Clinical psychology","level":1,"score":0.34435003995895386},{"id":"https://openalex.org/C526869908","wikidata":"https://www.wikidata.org/wiki/Q3298118","display_name":"Suicide prevention","level":3,"score":0.3367488384246826},{"id":"https://openalex.org/C2777503454","wikidata":"https://www.wikidata.org/wiki/Q415768","display_name":"Kynurenine","level":4,"score":0.31335166096687317},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.29256927967071533},{"id":"https://openalex.org/C169900460","wikidata":"https://www.wikidata.org/wiki/Q2200417","display_name":"Cognition","level":2,"score":0.2026178538799286},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.13198068737983704},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.11383888125419617},{"id":"https://openalex.org/C545542383","wikidata":"https://www.wikidata.org/wiki/Q2751242","display_name":"Medical emergency","level":1,"score":0.11242210865020752},{"id":"https://openalex.org/C2776706248","wikidata":"https://www.wikidata.org/wiki/Q181003","display_name":"Tryptophan","level":3,"score":0.09770730137825012},{"id":"https://openalex.org/C162324750","wikidata":"https://www.wikidata.org/wiki/Q8134","display_name":"Economics","level":0,"score":0.0},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C139719470","wikidata":"https://www.wikidata.org/wiki/Q39680","display_name":"Macroeconomics","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"doi:10.3389/fncel.2019.00031","doi":"https://doi.org/10.3389/fncel.2019.00031","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncel.2019.00031","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncel.2019.00031/pdf","source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:5381970","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC6381042","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:6381042","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/6381042","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Front Cell Neurosci","raw_type":"Text"},{"id":"pmid:30814929","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/30814929","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in cellular neuroscience","raw_type":"Journal Article"},{"id":"pmh:oai:doaj.org/article:5895fc90502945c7965e9dfd1abd49e7","doi":null,"is_oa":true,"landing_page_url":"https://doaj.org/article/5895fc90502945c7965e9dfd1abd49e7","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by-sa","license_id":"https://openalex.org/licenses/cc-by-sa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Frontiers in Cellular Neuroscience, Vol 13 (2019)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.3389/fncel.2019.00031","doi":"https://doi.org/10.3389/fncel.2019.00031","is_oa":true,"landing_page_url":"https://doi.org/10.3389/fncel.2019.00031","pdf_url":"https://www.frontiersin.org/articles/10.3389/fncel.2019.00031/pdf","source":{"id":"https://openalex.org/S36653316","display_name":"Frontiers in Cellular Neuroscience","issn_l":"1662-5102","issn":["1662-5102"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320527","host_organization_name":"Frontiers Media","host_organization_lineage":["https://openalex.org/P4310320527"],"host_organization_lineage_names":["Frontiers Media"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Frontiers in Cellular Neuroscience","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9922999739646912}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2383281604","display_name":"Development of the multidimensional assessment system for modern-type depression","funder_award_id":"15K15431","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G2542275816","display_name":"Translational research of psychiatric disorders focusing on neuron-glia interaction using regenerative medicine techniques","funder_award_id":"26713039","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G2602110344","display_name":"\u7cbe\u795e\u75be\u60a3\u306e\u75c5\u614b\u3092\u53cd\u6620\u3057\u305f\u9451\u5225\u8a3a\u65ad\u3001\u91cd\u75c7\u5ea6\u4e88\u6e2c\u304c\u53ef\u80fd\u306a\u8840\u4e2d\u30d0\u30a4\u30aa\u30de\u30fc\u30ab\u30fc\u306e\u5b9f\u7528\u5316\u7814\u7a76","funder_award_id":"17dk0307047h0003","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G3940536523","display_name":null,"funder_award_id":"JP18dk0307075","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G4208407426","display_name":null,"funder_award_id":"JP18dm0107095","funder_id":"https://openalex.org/F4320311405","funder_display_name":"Japan Agency for Medical Research and Development"},{"id":"https://openalex.org/G4960475182","display_name":"Clarifying the underlying pathophysiology of neuropsychiatric disorders using human-tissues-directly-derived neuronal/glial cells: Reverse-Translational Study.","funder_award_id":"18H04042","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G560452496","display_name":"metabomic analysis of mitochondria-ralted diseases","funder_award_id":"17H01550","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6077633771","display_name":"Psychological and psychiatric studies about the prevention and treatment of \"modern-type depression\"","funder_award_id":"16H03741","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6459711399","display_name":null,"funder_award_id":"JP16H06403","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G6809762567","display_name":null,"funder_award_id":"JP25117011","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7078834147","display_name":null,"funder_award_id":"16H06403","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G7263373431","display_name":"Development of clinical tests to predict the severity of depression or suicidal ideation.","funder_award_id":"18K07417","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8696244765","display_name":"Establishment of objective evaluation system for chronic fatigue syndrome using human peripheral blood induced microglia-like cells","funder_award_id":"17K19915","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"},{"id":"https://openalex.org/G8976421679","display_name":"Clarifying the underlying mechanisms of schizophrenia focusing on the abnormalities of neuronal activities and immune responses.","funder_award_id":"16H02666","funder_id":"https://openalex.org/F4320334764","funder_display_name":"Japan Society for the Promotion of Science"}],"funders":[{"id":"https://openalex.org/F4320311405","display_name":"Japan Agency for Medical Research and Development","ror":"https://ror.org/004rtk039"},{"id":"https://openalex.org/F4320325287","display_name":"SENSHIN Medical Research Foundation","ror":"https://ror.org/021tj4g88"},{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","ror":"https://ror.org/00hhkn466"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W2912835554.pdf","grobid_xml":"https://content.openalex.org/works/W2912835554.grobid-xml"},"referenced_works_count":105,"referenced_works":["https://openalex.org/W1512272053","https://openalex.org/W1530111369","https://openalex.org/W1576427485","https://openalex.org/W1903007678","https://openalex.org/W1913910481","https://openalex.org/W1927796084","https://openalex.org/W1970022478","https://openalex.org/W1972578501","https://openalex.org/W1975952150","https://openalex.org/W1976293588","https://openalex.org/W1976899564","https://openalex.org/W1978238793","https://openalex.org/W1978830885","https://openalex.org/W1982896592","https://openalex.org/W1984103995","https://openalex.org/W1985001669","https://openalex.org/W1989148964","https://openalex.org/W1989457118","https://openalex.org/W1989580462","https://openalex.org/W1990151307","https://openalex.org/W1996791907","https://openalex.org/W1997132311","https://openalex.org/W1998248914","https://openalex.org/W2003048056","https://openalex.org/W2003316287","https://openalex.org/W2007076376","https://openalex.org/W2012520574","https://openalex.org/W2018049815","https://openalex.org/W2018838561","https://openalex.org/W2019203176","https://openalex.org/W2021260035","https://openalex.org/W2027018469","https://openalex.org/W2028249314","https://openalex.org/W2030400690","https://openalex.org/W2030457183","https://openalex.org/W2031648971","https://openalex.org/W2038927970","https://openalex.org/W2040268226","https://openalex.org/W2044390612","https://openalex.org/W2051359369","https://openalex.org/W2055909204","https://openalex.org/W2059032097","https://openalex.org/W2061657865","https://openalex.org/W2063682731","https://openalex.org/W2067267561","https://openalex.org/W2079882622","https://openalex.org/W2082633183","https://openalex.org/W2087146795","https://openalex.org/W2093493917","https://openalex.org/W2108598556","https://openalex.org/W2110558605","https://openalex.org/W2112726857","https://openalex.org/W2112951712","https://openalex.org/W2115585096","https://openalex.org/W2117769093","https://openalex.org/W2120306544","https://openalex.org/W2127064468","https://openalex.org/W2127897405","https://openalex.org/W2131908174","https://openalex.org/W2132867079","https://openalex.org/W2138517367","https://openalex.org/W2141677575","https://openalex.org/W2141701219","https://openalex.org/W2146758523","https://openalex.org/W2151283331","https://openalex.org/W2152674565","https://openalex.org/W2159816974","https://openalex.org/W2161548283","https://openalex.org/W2162460585","https://openalex.org/W2163622987","https://openalex.org/W2170490236","https://openalex.org/W2252494449","https://openalex.org/W2284323937","https://openalex.org/W2320665292","https://openalex.org/W2338925098","https://openalex.org/W2343003799","https://openalex.org/W2346546064","https://openalex.org/W2394936631","https://openalex.org/W2479496252","https://openalex.org/W2504229998","https://openalex.org/W2508885228","https://openalex.org/W2522122785","https://openalex.org/W2556540841","https://openalex.org/W2563838741","https://openalex.org/W2585717798","https://openalex.org/W2587374695","https://openalex.org/W2591521134","https://openalex.org/W2606077861","https://openalex.org/W2611406986","https://openalex.org/W2733689132","https://openalex.org/W2743887053","https://openalex.org/W2752390206","https://openalex.org/W2752766390","https://openalex.org/W2754547625","https://openalex.org/W2787897432","https://openalex.org/W2793738947","https://openalex.org/W2794645689","https://openalex.org/W2798127117","https://openalex.org/W2808718833","https://openalex.org/W2809640039","https://openalex.org/W2884380633","https://openalex.org/W2890191325","https://openalex.org/W2900469473","https://openalex.org/W2905317594","https://openalex.org/W4211120965"],"related_works":["https://openalex.org/W6960906805","https://openalex.org/W3048903427","https://openalex.org/W3202080572","https://openalex.org/W4280532627","https://openalex.org/W2120306544","https://openalex.org/W4399055099","https://openalex.org/W4391761834","https://openalex.org/W2591521134","https://openalex.org/W1999709108","https://openalex.org/W4322615335"],"abstract_inverted_index":{"Suicide":[0,138],"is":[1,139],"one":[2,80],"of":[3,81,130,153,184,230],"the":[4,43,82,96,151,180,216,228],"most":[5],"disastrous":[6],"outcomes":[7],"for":[8],"psychiatric":[9,30,65,104,121],"disorders.":[10],"Recent":[11],"advances":[12],"in":[13,29,42,51,232],"biological":[14,167],"psychiatry":[15],"have":[16,75,134],"suggested":[17,60,77],"a":[18,107],"positive":[19],"relationship":[20],"between":[21],"some":[22],"specific":[23,27],"brain":[24,52,183],"abnormalities":[25],"and":[26,58,70,88,158,172,199,224,247],"symptoms":[28],"disorders":[31,66,105],"whose":[32],"organic":[33],"bases":[34],"were":[35],"previously":[36],"completely":[37],"unknown.":[38],"Microglia,":[39],"immune":[40],"cells":[41,85],"brain,":[44],"are":[45,59,112],"regarded":[46],"to":[47,61,63,78,86,125,141,144,226],"play":[48],"crucial":[49],"roles":[50],"inflammation":[53],"by":[54],"releasing":[55],"inflammatory":[56],"mediators":[57],"contribute":[62],"various":[64,92,156],"such":[67],"as":[68],"depression":[69],"schizophrenia.":[71],"Recently,":[72],"activated":[73],"microglia":[74,231],"been":[76,136],"be":[79,142,150],"possible":[83],"contributing":[84],"suicide":[87,171,185,233,248],"suicidal":[89,132,208,243],"behaviors":[90,133,212,246],"via":[91],"mechanisms":[93],"especially":[94,213],"including":[95],"tryptophan-kynurenine":[97,217],"pathway.":[98,218],"Animal":[99],"model":[100],"research":[101,154],"focusing":[102,169,214,238],"on":[103,170,193,204,215,239],"has":[106],"long":[108],"history,":[109],"however,":[110],"there":[111],"only":[113],"limited":[114,143],"animal":[115,128],"models":[116,129],"that":[117],"can":[118],"properly":[119],"express":[120],"symptoms.":[122],"In":[123],"particular,":[124],"our":[126],"knowledge,":[127],"human":[131,147,166,181,240],"not":[135],"established.":[137],"believed":[140],"humans,":[145],"therefore":[146],"subjects":[148,206,241],"should":[149],"targets":[152],"despite":[155],"ethical":[157],"technical":[159],"limitations.":[160],"From":[161],"this":[162],"perspective,":[163],"we":[164,188,220],"introduce":[165],"studies":[168,178],"microglia.":[173],"We":[174],"first":[175],"present":[176],"neuropathological":[177],"using":[179,234],"postmortem":[182],"victims.":[186,249],"Second,":[187],"show":[189],"recent":[190],"findings":[191],"based":[192],"positron":[194],"emission":[195],"tomography":[196],"(PET)":[197],"imaging":[198],"peripheral":[200],"blood":[201],"biomarker":[202],"analysis":[203],"living":[205],"with":[207,242],"ideation":[209],"and/or":[210],"suicide-related":[211,245],"Finally,":[219],"propose":[221],"future":[222],"perspectives":[223],"tasks":[225],"clarify":[227],"role":[229],"multi-dimensional":[235],"analytical":[236],"methods":[237],"ideation,":[244]},"counts_by_year":[{"year":2026,"cited_by_count":3},{"year":2025,"cited_by_count":12},{"year":2024,"cited_by_count":15},{"year":2023,"cited_by_count":8},{"year":2022,"cited_by_count":12},{"year":2021,"cited_by_count":93},{"year":2020,"cited_by_count":46},{"year":2019,"cited_by_count":12}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2019-02-21T00:00:00"}