{"id":"https://openalex.org/W2912769711","doi":"https://doi.org/10.1002/047001153x.g409218","title":"RNA secondary structure prediction","display_name":"RNA secondary structure prediction","publication_year":2005,"publication_date":"2005-04-15","ids":{"openalex":"https://openalex.org/W2912769711","doi":"https://doi.org/10.1002/047001153x.g409218","mag":"2912769711"},"language":"en","primary_location":{"id":"doi:10.1002/047001153x.g409218","doi":"https://doi.org/10.1002/047001153x.g409218","is_oa":false,"landing_page_url":"https://doi.org/10.1002/047001153x.g409218","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics","raw_type":"other"},"volume":{"id":"https://openalex.org/W2740163983","display_name":"Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics"},"type":"reference-entry","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5002272329","display_name":"David H. Mathews","orcid":"https://orcid.org/0000-0002-2907-6557","observed_orcids":["https://orcid.org/0000-0002-2907-6557","https://orcid.org/0000-0002-4695-0269"]},"institutions":[{"id":"https://openalex.org/I28792581","display_name":"University of Rochester Medicine","ror":"https://ror.org/00trqv719","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I28792581","https://openalex.org/I5388228"]},{"id":"https://openalex.org/I5388228","display_name":"University of Rochester","ror":"https://ror.org/022kthw22","country_code":"US","type":"education","lineage":["https://openalex.org/I5388228"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"David H. Mathews","raw_affiliation_strings":["University of Rochester Medical Center, Rochester, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Rochester Medical Center, Rochester, NY, USA","institution_ids":["https://openalex.org/I28792581","https://openalex.org/I5388228"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5085603729","display_name":"Michael Zuker","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I165799507","display_name":"Rensselaer Polytechnic Institute","ror":"https://ror.org/01rtyzb94","country_code":"US","type":"education","lineage":["https://openalex.org/I165799507"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Michael Zuker","raw_affiliation_strings":["Rensselaer Polytechnic Institute, Troy, NY, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Rensselaer Polytechnic Institute, Troy, NY, USA","institution_ids":["https://openalex.org/I165799507"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":17,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies","score":0.0005000000237487257,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rna-secondary-structure-prediction","display_name":"RNA secondary structure prediction","score":0.9860000014305115},{"id":"https://openalex.org/keywords/thermodynamic-parameters","display_name":"thermodynamic parameters","score":0.7979999780654907},{"id":"https://openalex.org/keywords/free-energy","display_name":"free energy","score":0.8550000190734863},{"id":"https://openalex.org/keywords/multiple-sequence-alignment","display_name":"multiple sequence alignment","score":0.6809999942779541},{"id":"https://openalex.org/keywords/rna-folding","display_name":"RNA folding","score":0.5699999928474426},{"id":"https://openalex.org/keywords/prediction-algorithm","display_name":"prediction algorithm","score":0.6970000267028809}],"concepts":[{"id":"https://openalex.org/C62614982","wikidata":"https://www.wikidata.org/wiki/Q904984","display_name":"Protein secondary structure","level":2,"score":0.6905604600906372},{"id":"https://openalex.org/C85468374","wikidata":"https://www.wikidata.org/wiki/Q6589957","display_name":"Nucleic acid secondary structure","level":4,"score":0.6223362684249878},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.6067333221435547},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.5158423781394958},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.46778735518455505},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4267778992652893},{"id":"https://openalex.org/C2777904410","wikidata":"https://www.wikidata.org/wiki/Q7397","display_name":"Software","level":2,"score":0.4265480935573578},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3313356637954712},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.26139724254608154},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.13842719793319702},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/047001153x.g409218","doi":"https://doi.org/10.1002/047001153x.g409218","is_oa":false,"landing_page_url":"https://doi.org/10.1002/047001153x.g409218","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":56,"referenced_works":["https://openalex.org/W1519185585","https://openalex.org/W1543796220","https://openalex.org/W1910105722","https://openalex.org/W1964180701","https://openalex.org/W1968245790","https://openalex.org/W1978288629","https://openalex.org/W1978388370","https://openalex.org/W1980410097","https://openalex.org/W1980816809","https://openalex.org/W1984675364","https://openalex.org/W1995403172","https://openalex.org/W2000191287","https://openalex.org/W2004116872","https://openalex.org/W2004945910","https://openalex.org/W2009215595","https://openalex.org/W2009265617","https://openalex.org/W2009736453","https://openalex.org/W2009818318","https://openalex.org/W2010855589","https://openalex.org/W2017313617","https://openalex.org/W2018216725","https://openalex.org/W2020195960","https://openalex.org/W2020865862","https://openalex.org/W2024799598","https://openalex.org/W2025763720","https://openalex.org/W2039383512","https://openalex.org/W2039951296","https://openalex.org/W2040015982","https://openalex.org/W2045895660","https://openalex.org/W2049446075","https://openalex.org/W2051713039","https://openalex.org/W2059367569","https://openalex.org/W2074466923","https://openalex.org/W2076756368","https://openalex.org/W2080368679","https://openalex.org/W2090030959","https://openalex.org/W2095145214","https://openalex.org/W2101176469","https://openalex.org/W2102107103","https://openalex.org/W2103250001","https://openalex.org/W2104141342","https://openalex.org/W2114110579","https://openalex.org/W2117431427","https://openalex.org/W2123241418","https://openalex.org/W2136654689","https://openalex.org/W2140651796","https://openalex.org/W2141157874","https://openalex.org/W2151922790","https://openalex.org/W2153140501","https://openalex.org/W2155544170","https://openalex.org/W2159123055","https://openalex.org/W2159548583","https://openalex.org/W2167557255","https://openalex.org/W2169239541","https://openalex.org/W3146204257","https://openalex.org/W4237573105"],"related_works":["https://openalex.org/W2009818318","https://openalex.org/W1979988863","https://openalex.org/W4415615477","https://openalex.org/W2480569476","https://openalex.org/W2523592638","https://openalex.org/W2061158331","https://openalex.org/W2098571862","https://openalex.org/W7096257368","https://openalex.org/W2098553089","https://openalex.org/W2143622792"],"abstract_inverted_index":{"Abstract":[0],"The":[1,23],"field":[2],"of":[3,17,31,44],"RNA":[4,33],"secondary":[5,34,52],"structure":[6,35,53],"prediction":[7,54],"matured":[8],"in":[9],"the":[10,15,28,42,50],"last":[11],"10":[12],"years":[13],"with":[14],"development":[16],"many":[18],"readily":[19],"available":[20,51],"software":[21],"packages.":[22],"thermodynamic":[24],"parameters":[25],"for":[26,56],"predicting":[27],"free":[29],"energy":[30],"an":[32],"are":[36],"continuing":[37],"to":[38],"be":[39],"revised":[40],"on":[41],"basis":[43],"new":[45],"experiments.":[46],"This":[47],"article":[48],"reviews":[49],"algorithms":[55],"both":[57],"a":[58],"single":[59],"sequence":[60],"and":[61],"multiple":[62],"sequences.":[63]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-05T12:25:35.769452","created_date":"2019-02-21T00:00:00"}